[go: up one dir, main page]

WO2004080382A3 - Nouvelles compositions - Google Patents

Nouvelles compositions Download PDF

Info

Publication number
WO2004080382A3
WO2004080382A3 PCT/GB2004/001037 GB2004001037W WO2004080382A3 WO 2004080382 A3 WO2004080382 A3 WO 2004080382A3 GB 2004001037 W GB2004001037 W GB 2004001037W WO 2004080382 A3 WO2004080382 A3 WO 2004080382A3
Authority
WO
WIPO (PCT)
Prior art keywords
compositions containing
novel compositions
containing fentanyl
fentanyl
formulations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB2004/001037
Other languages
English (en)
Other versions
WO2004080382A2 (fr
Inventor
Calvin Ross
Clive Booles
Alistair Campbell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SIRUS PHARMACEUTICALS Ltd
Original Assignee
SIRUS PHARMACEUTICALS Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0305579.5A external-priority patent/GB0305579D0/en
Priority to CA002516338A priority Critical patent/CA2516338A1/fr
Priority to BRPI0408209-5A priority patent/BRPI0408209A/pt
Priority to NZ541781A priority patent/NZ541781A/en
Priority to HK05112165.9A priority patent/HK1084012A1/zh
Priority to AU2004218876A priority patent/AU2004218876B2/en
Priority to EP04719527A priority patent/EP1608372A2/fr
Priority to JP2006500257A priority patent/JP2006519770A/ja
Priority to CN2004800051154A priority patent/CN1784228B/zh
Application filed by SIRUS PHARMACEUTICALS Ltd filed Critical SIRUS PHARMACEUTICALS Ltd
Priority to MXPA05009602A priority patent/MXPA05009602A/es
Publication of WO2004080382A2 publication Critical patent/WO2004080382A2/fr
Publication of WO2004080382A3 publication Critical patent/WO2004080382A3/fr
Priority to NO20054172A priority patent/NO20054172L/no
Anticipated expiration legal-status Critical
Priority to US11/224,383 priority patent/US20060062812A1/en
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4468Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Cette invention a trait à des préparations à base de fentanyl, notamment à des préparations pour atomiseurs, utilisables pour une administration par voie sublinguale.
PCT/GB2004/001037 2003-03-11 2004-03-11 Nouvelles compositions Ceased WO2004080382A2 (fr)

Priority Applications (11)

Application Number Priority Date Filing Date Title
MXPA05009602A MXPA05009602A (es) 2003-03-11 2004-03-11 Composiciones novedosas.
EP04719527A EP1608372A2 (fr) 2003-03-11 2004-03-11 Compositions contenant du fentanyle
BRPI0408209-5A BRPI0408209A (pt) 2003-03-11 2004-03-11 novas composições
NZ541781A NZ541781A (en) 2003-03-11 2004-03-11 Novel compositions containing fentanyl
HK05112165.9A HK1084012A1 (zh) 2003-03-11 2004-03-11 新颖成分
AU2004218876A AU2004218876B2 (en) 2003-03-11 2004-03-11 Novel compositions containing fentanyl
JP2006500257A JP2006519770A (ja) 2003-03-11 2004-03-11 新規組成物
CA002516338A CA2516338A1 (fr) 2003-03-11 2004-03-11 Nouvelles compositions
CN2004800051154A CN1784228B (zh) 2003-03-11 2004-03-11 新组合物
NO20054172A NO20054172L (no) 2003-03-11 2005-09-07 Nye blandinger
US11/224,383 US20060062812A1 (en) 2003-03-11 2005-09-12 Novel compositions

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0305579.5 2003-03-11
GBGB0305579.5A GB0305579D0 (en) 2003-03-11 2003-03-11 Pharmaceutical compositions
GB0328023.7 2003-12-03
GB0328023A GB2399286A (en) 2003-03-11 2003-12-03 Sub-lingual fentanyl formulation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US11/224,383 Continuation-In-Part US20060062812A1 (en) 2003-03-11 2005-09-12 Novel compositions

Publications (2)

Publication Number Publication Date
WO2004080382A2 WO2004080382A2 (fr) 2004-09-23
WO2004080382A3 true WO2004080382A3 (fr) 2005-03-24

Family

ID=32992592

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2004/001037 Ceased WO2004080382A2 (fr) 2003-03-11 2004-03-11 Nouvelles compositions

Country Status (10)

Country Link
EP (1) EP1608372A2 (fr)
JP (1) JP2006519770A (fr)
KR (1) KR20050115276A (fr)
AU (1) AU2004218876B2 (fr)
BR (1) BRPI0408209A (fr)
CA (1) CA2516338A1 (fr)
MX (1) MXPA05009602A (fr)
NO (1) NO20054172L (fr)
NZ (1) NZ541781A (fr)
WO (1) WO2004080382A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006089082A2 (fr) * 2005-02-17 2006-08-24 Velcera Pharmaceuticals Administration par voie transmuqueuse de compositions medicamenteuses pour le traitement et la prevention de troubles chez les animaux
GB0514043D0 (en) 2005-07-08 2005-08-17 Arakis Ltd Fentanyl formulation
JP5241514B2 (ja) 2006-01-25 2013-07-17 インシス セラピューティクス インコーポレイテッド 舌下フェンタニルスプレー
PL2180844T3 (pl) 2007-08-02 2018-07-31 Insys Development Company, Inc. Rozpylacz podjęzykowy z fentanylem
GB2476494A (en) * 2009-12-24 2011-06-29 Norwich Pharma Technologies Ltd Formulation for the sublingual delivery of sufentanil

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999016417A1 (fr) * 1997-10-01 1999-04-08 Flemington Pharmaceutical Corporation Pulverisation ou capsule buccale, polaire et non polaire
US5958379A (en) * 1994-09-30 1999-09-28 Mika Pharma Gesellschaft Fuer Die Entwicklung Und Vermarktung Pharmazeutischer Producte Mbh Pharmaceutical composition
WO2000016751A1 (fr) * 1998-09-24 2000-03-30 Diabact Ab Composition de fentanyl pour le traitement des douleurs aigues
WO2000047203A1 (fr) * 1999-02-12 2000-08-17 Mqs, Inc. Formulation et systeme pour administration intra-orale de principes actifs
WO2002011778A1 (fr) * 2000-05-10 2002-02-14 University Of Kentucky Research Foundation Systeme et procede d'administration intranasale d'opioides
WO2002051380A1 (fr) * 2000-12-22 2002-07-04 Audit Institute For Medical Services And Quality Assurance Gmbh Nouvelle composition pharmaceutique de principes actifs solubles dans l'eau ou peu solubles dans l'eau
US20030035831A1 (en) * 1998-12-21 2003-02-20 Pankaj Modi Pharmaceutical compositions for buccal delivery of pain relief medications
US20030185761A1 (en) * 1997-10-01 2003-10-02 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating pain

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5958379A (en) * 1994-09-30 1999-09-28 Mika Pharma Gesellschaft Fuer Die Entwicklung Und Vermarktung Pharmazeutischer Producte Mbh Pharmaceutical composition
WO1999016417A1 (fr) * 1997-10-01 1999-04-08 Flemington Pharmaceutical Corporation Pulverisation ou capsule buccale, polaire et non polaire
US20030185761A1 (en) * 1997-10-01 2003-10-02 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing drugs for treating pain
WO2000016751A1 (fr) * 1998-09-24 2000-03-30 Diabact Ab Composition de fentanyl pour le traitement des douleurs aigues
US20030035831A1 (en) * 1998-12-21 2003-02-20 Pankaj Modi Pharmaceutical compositions for buccal delivery of pain relief medications
WO2000047203A1 (fr) * 1999-02-12 2000-08-17 Mqs, Inc. Formulation et systeme pour administration intra-orale de principes actifs
WO2002011778A1 (fr) * 2000-05-10 2002-02-14 University Of Kentucky Research Foundation Systeme et procede d'administration intranasale d'opioides
WO2002051380A1 (fr) * 2000-12-22 2002-07-04 Audit Institute For Medical Services And Quality Assurance Gmbh Nouvelle composition pharmaceutique de principes actifs solubles dans l'eau ou peu solubles dans l'eau

Also Published As

Publication number Publication date
NO20054172D0 (no) 2005-09-07
AU2004218876B2 (en) 2007-08-02
JP2006519770A (ja) 2006-08-31
MXPA05009602A (es) 2005-11-08
EP1608372A2 (fr) 2005-12-28
CA2516338A1 (fr) 2004-09-23
NZ541781A (en) 2008-04-30
BRPI0408209A (pt) 2006-02-14
NO20054172L (no) 2005-10-06
KR20050115276A (ko) 2005-12-07
WO2004080382A2 (fr) 2004-09-23
AU2004218876A1 (en) 2004-09-23

Similar Documents

Publication Publication Date Title
MXPA05012025A (es) Imidazo y tiazolopiridinas como inhibidores de cinasa jak3.
UA86591C2 (ru) Пирролодигидроизохинолины как ингибиторы pde10, фармацевтическая композиция на их основе
MXPA05012026A (es) Compuestos de azaindol como inhibidores de cinasa.
WO2004074244A3 (fr) Composes de pyrimidine
WO2004082822A3 (fr) Procedes permettant d'isoler la forme i cristalline de la 5-azacytidine
WO2008064353A3 (fr) Analogues 4,5-époxy-morphinanium saturé en position 7 et 8
EP1615621A4 (fr) Compositions d'administration de combinaisons de medicaments
SE0101675D0 (sv) Novel composition
WO2008070462A3 (fr) N-oxydes d'analogues 4,5-époxy-morphinanium
WO2006021213A3 (fr) Antagonistes de récepteur v1a la vasopressine v1a
PH12013501567B1 (en) Anti-malarial pharmaceutical composition
WO2005030188A3 (fr) Derives de phenyl-piperazine en tant que modulateurs des recepteurs muscariniques
WO2003017924A3 (fr) Stereo-isomeres de lipopeptide, methodes de preparation afferentes et intermediaires utiles
WO2005085236A3 (fr) Inhibiteurs de la caspase et leurs utilisations
WO2004087652A3 (fr) Composes d'imidazotriazine
WO2004080382A3 (fr) Nouvelles compositions
GB0514043D0 (en) Fentanyl formulation
MY142076A (en) Emulsifying systems containing azetidine derivatives
WO2005060981A3 (fr) Compositions pharmaceutiques
WO2007087026A3 (fr) Forme solide de amg 706 et compositions pharmaceutiques contenant ledit composé
WO2004089281A3 (fr) Nouveaux corps polymorphes de tartrate de tolterodine
WO2003097593A3 (fr) Inhibiteurs de protease
WO2006055663A3 (fr) Nouvelle utilisation
WO2006059304A3 (fr) Nouveaux derives bicycliques
WO2004039352A3 (fr) Forme amorphe de losartan potassium

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 3409/DELNP/2005

Country of ref document: IN

WWE Wipo information: entry into national phase

Ref document number: 170058

Country of ref document: IL

WWE Wipo information: entry into national phase

Ref document number: 2005/06248

Country of ref document: ZA

Ref document number: 200506248

Country of ref document: ZA

WWE Wipo information: entry into national phase

Ref document number: 541781

Country of ref document: NZ

WWE Wipo information: entry into national phase

Ref document number: 2516338

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2004218876

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 20048051154

Country of ref document: CN

WWE Wipo information: entry into national phase

Ref document number: PA/a/2005/009602

Country of ref document: MX

WWE Wipo information: entry into national phase

Ref document number: 1020057016853

Country of ref document: KR

Ref document number: 2006500257

Country of ref document: JP

WWE Wipo information: entry into national phase

Ref document number: 11224383

Country of ref document: US

ENP Entry into the national phase

Ref document number: 2004218876

Country of ref document: AU

Date of ref document: 20040311

Kind code of ref document: A

WWP Wipo information: published in national office

Ref document number: 2004218876

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 2004719527

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 1020057016853

Country of ref document: KR

WWP Wipo information: published in national office

Ref document number: 2004719527

Country of ref document: EP

ENP Entry into the national phase

Ref document number: PI0408209

Country of ref document: BR

WWP Wipo information: published in national office

Ref document number: 11224383

Country of ref document: US

WWG Wipo information: grant in national office

Ref document number: 2004218876

Country of ref document: AU