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WO2004065939A3 - Methods for diagnosing osteoporosis or a susceptibility to osteoporosis based on haplotype association - Google Patents

Methods for diagnosing osteoporosis or a susceptibility to osteoporosis based on haplotype association Download PDF

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Publication number
WO2004065939A3
WO2004065939A3 PCT/US2004/000991 US2004000991W WO2004065939A3 WO 2004065939 A3 WO2004065939 A3 WO 2004065939A3 US 2004000991 W US2004000991 W US 2004000991W WO 2004065939 A3 WO2004065939 A3 WO 2004065939A3
Authority
WO
WIPO (PCT)
Prior art keywords
osteoporosis
susceptibility
methods
diagnosing
haplotype association
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2004/000991
Other languages
French (fr)
Other versions
WO2004065939A2 (en
Inventor
Unnur Styrkarsdottir
Jean-Baptiste Cazier
Jeffrey R Gulcher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Decode Genetics ehf
Original Assignee
Decode Genetics ehf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Decode Genetics ehf filed Critical Decode Genetics ehf
Priority to CA002512549A priority Critical patent/CA2512549A1/en
Priority to EP04702516A priority patent/EP1585838A2/en
Priority to JP2006500966A priority patent/JP2006516196A/en
Publication of WO2004065939A2 publication Critical patent/WO2004065939A2/en
Publication of WO2004065939A3 publication Critical patent/WO2004065939A3/en
Anticipated expiration legal-status Critical
Priority to US11/185,033 priority patent/US20060057612A1/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Methods for diagnosis of osteoporosis or a susceptibility to osteoporosis based on detection of at risk haplotypes associated with BMP2 are disclosed.
PCT/US2004/000991 2000-09-14 2004-01-15 Methods for diagnosing osteoporosis or a susceptibility to osteoporosis based on haplotype association Ceased WO2004065939A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002512549A CA2512549A1 (en) 2003-01-16 2004-01-15 Methods for diagnosing osteoporosis or a susceptibility to osteoporosis based on haplotype association
EP04702516A EP1585838A2 (en) 2003-01-16 2004-01-15 Methods for diagnosing osteoporosis or a susceptibility to osteoporosis based on haplotype association
JP2006500966A JP2006516196A (en) 2003-01-16 2004-01-15 Diagnosis method of susceptibility to osteoporosis or osteoporosis based on haplotype association
US11/185,033 US20060057612A1 (en) 2000-09-14 2005-07-18 Methods for diagnosing osteoporosis or a susceptibility to osteoporosis based on haplotype association

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US44089903P 2003-01-16 2003-01-16
US60/440,899 2003-01-16
US45065203P 2003-02-27 2003-02-27
US60/450,652 2003-02-27

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US11/185,033 Continuation-In-Part US20060057612A1 (en) 2000-09-14 2005-07-18 Methods for diagnosing osteoporosis or a susceptibility to osteoporosis based on haplotype association

Publications (2)

Publication Number Publication Date
WO2004065939A2 WO2004065939A2 (en) 2004-08-05
WO2004065939A3 true WO2004065939A3 (en) 2004-09-02

Family

ID=32776037

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/000991 Ceased WO2004065939A2 (en) 2000-09-14 2004-01-15 Methods for diagnosing osteoporosis or a susceptibility to osteoporosis based on haplotype association

Country Status (4)

Country Link
EP (1) EP1585838A2 (en)
JP (1) JP2006516196A (en)
CA (1) CA2512549A1 (en)
WO (1) WO2004065939A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2641315A1 (en) * 2006-02-06 2007-08-16 Tethys Bioscience, Inc. Osteoporosis associated markers and methods of use thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001016377A2 (en) * 1999-08-30 2001-03-08 Interleukin Genetics, Inc. Diagnostics and therapeutics for osteoporosis
WO2002022871A2 (en) * 2000-09-14 2002-03-21 Decode Genetics Ehf Polymorphic bone morphogenetic protein 2

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004065938A2 (en) * 2000-09-14 2004-08-05 Decode Genetics Ehf. Human osteoporosis gene

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001016377A2 (en) * 1999-08-30 2001-03-08 Interleukin Genetics, Inc. Diagnostics and therapeutics for osteoporosis
WO2002022871A2 (en) * 2000-09-14 2002-03-21 Decode Genetics Ehf Polymorphic bone morphogenetic protein 2

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
See also references of EP1585838A2 *
STYRKARSDOTTIR UNNUR ET AL: "Linkage of Osteoporosis to Chromosome 20p12 and Association to BMP2.", December 2003, PLOS BIOLOGY. DEC 2003, VOL. 1, NR. 3, PAGE(S) E69, ISSN: 1544-9173, XP002286775 *

Also Published As

Publication number Publication date
WO2004065939A2 (en) 2004-08-05
JP2006516196A (en) 2006-06-29
EP1585838A2 (en) 2005-10-19
CA2512549A1 (en) 2004-08-05

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