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WO2004062640A3 - Capsule pour recevoir un principe actif administrable par inhalation - Google Patents

Capsule pour recevoir un principe actif administrable par inhalation Download PDF

Info

Publication number
WO2004062640A3
WO2004062640A3 PCT/EP2003/014694 EP0314694W WO2004062640A3 WO 2004062640 A3 WO2004062640 A3 WO 2004062640A3 EP 0314694 W EP0314694 W EP 0314694W WO 2004062640 A3 WO2004062640 A3 WO 2004062640A3
Authority
WO
WIPO (PCT)
Prior art keywords
capsule
administrable
inhalation
receiving
active substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2003/014694
Other languages
German (de)
English (en)
Other versions
WO2004062640A2 (fr
Inventor
Dieter Hochrainer
Heinrich Kladders
Burkhard Metzger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim International GmbH
Original Assignee
Boehringer Ingelheim International GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International GmbH filed Critical Boehringer Ingelheim International GmbH
Priority to CA2513201A priority Critical patent/CA2513201C/fr
Priority to JP2004566013A priority patent/JP2006517421A/ja
Priority to EP03799497A priority patent/EP1587564A2/fr
Priority to AU2003300220A priority patent/AU2003300220A1/en
Publication of WO2004062640A2 publication Critical patent/WO2004062640A2/fr
Publication of WO2004062640A3 publication Critical patent/WO2004062640A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0035—Piercing means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0048—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)

Abstract

L'invention concerne une nouvelle capsule pour la réception d'un principe actif administrable par inhalation. La capsule selon l'invention est de préférence destinée à être utilisée dans un inhalateur de poudre fonctionnant selon le principe de Bernoulli.
PCT/EP2003/014694 2003-01-14 2003-12-20 Capsule pour recevoir un principe actif administrable par inhalation Ceased WO2004062640A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA2513201A CA2513201C (fr) 2003-01-14 2003-12-20 Capsule pour recevoir un principe actif administrable par inhalation
JP2004566013A JP2006517421A (ja) 2003-01-14 2003-12-20 吸入により投与される有効物質を受け入れるためのカプセル
EP03799497A EP1587564A2 (fr) 2003-01-14 2003-12-20 Capsule pour recevoir un principe actif administrable par inhalation
AU2003300220A AU2003300220A1 (en) 2003-01-14 2003-12-20 Capsule for receiving an active substance which is administrable by inhalation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2003100984 DE10300984A1 (de) 2003-01-14 2003-01-14 Kapsel zur Aufnahme eines inhalativ applizierbaren Wirkstoffs
DE10300984.1 2003-01-14

Publications (2)

Publication Number Publication Date
WO2004062640A2 WO2004062640A2 (fr) 2004-07-29
WO2004062640A3 true WO2004062640A3 (fr) 2004-10-21

Family

ID=32519907

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2003/014694 Ceased WO2004062640A2 (fr) 2003-01-14 2003-12-20 Capsule pour recevoir un principe actif administrable par inhalation

Country Status (6)

Country Link
EP (1) EP1587564A2 (fr)
JP (1) JP2006517421A (fr)
AU (1) AU2003300220A1 (fr)
CA (1) CA2513201C (fr)
DE (1) DE10300984A1 (fr)
WO (1) WO2004062640A2 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007036411A1 (de) 2007-07-20 2009-02-12 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverinhalator
TR200803525A2 (tr) * 2008-05-16 2009-12-21 Bi̇lgi̇ç Mahmut Toz ilaç soluma cihazı.
JP5415341B2 (ja) * 2010-03-31 2014-02-12 株式会社吉野工業所 粉体吸入デバイス
US10220165B2 (en) * 2011-05-27 2019-03-05 Boehringer Ingelheim International Gmbh Inhalator and capsule for an inhalator
PT107627B (pt) * 2014-04-29 2017-03-08 Hovione Farmaciência S A Inalador de cápsulas com dobradiça
EP3167867A1 (fr) * 2015-11-16 2017-05-17 Capsugel Belgium NV Forme posologique inviolable
EP3167868A1 (fr) * 2015-11-16 2017-05-17 Capsugel Belgium NV Forme posologique inviolable
CN111012671B (zh) * 2019-11-25 2022-07-05 上海强德食品科技有限公司 一种微胶囊的物理制备方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0143524A1 (fr) * 1983-09-23 1985-06-05 Lilly Industries Limited Capsule en deux parties
DE3927170A1 (de) * 1989-08-17 1991-02-21 Boehringer Ingelheim Kg Inhalator
EP0911047A1 (fr) * 1993-06-03 1999-04-28 Boehringer Ingelheim Pharma KG Porte-capsules
DE19835346A1 (de) * 1998-08-05 2000-02-10 Boehringer Ingelheim Pharma Zweiteilige Kapsel zur Aufnahme von pharmazeutischen Zubereitungen für Pulverinhalatoren
GB2356842A (en) * 1999-11-17 2001-06-06 Aquasol Ltd Injection-moulded capsules

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE395611B (sv) * 1975-12-12 1977-08-22 Draco Ab Aerosolinhalationsanordning avsedd for inhalering genom ett inhaleringsmunstycke av farmakologiskt aktiva substanser
DE3345722A1 (de) * 1983-12-17 1985-06-27 Boehringer Ingelheim KG, 6507 Ingelheim Inhalator
AU650953B2 (en) * 1991-03-21 1994-07-07 Novartis Ag Inhaler
JP3372105B2 (ja) * 1994-05-26 2003-01-27 株式会社日立ユニシアオートモティブ 吸入式投薬器

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0143524A1 (fr) * 1983-09-23 1985-06-05 Lilly Industries Limited Capsule en deux parties
DE3927170A1 (de) * 1989-08-17 1991-02-21 Boehringer Ingelheim Kg Inhalator
EP0911047A1 (fr) * 1993-06-03 1999-04-28 Boehringer Ingelheim Pharma KG Porte-capsules
DE19835346A1 (de) * 1998-08-05 2000-02-10 Boehringer Ingelheim Pharma Zweiteilige Kapsel zur Aufnahme von pharmazeutischen Zubereitungen für Pulverinhalatoren
WO2000007572A2 (fr) * 1998-08-05 2000-02-17 Boehringer Ingelheim Pharma Kg Capsule en deux parties pour preparations pharmaceutiques destinees aux inhalateurs de medicaments en poudre
GB2356842A (en) * 1999-11-17 2001-06-06 Aquasol Ltd Injection-moulded capsules

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1587564A2 *

Also Published As

Publication number Publication date
AU2003300220A1 (en) 2004-08-10
EP1587564A2 (fr) 2005-10-26
CA2513201A1 (fr) 2004-07-29
AU2003300220A8 (en) 2004-08-10
WO2004062640A2 (fr) 2004-07-29
JP2006517421A (ja) 2006-07-27
CA2513201C (fr) 2012-10-02
DE10300984A1 (de) 2004-07-22

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