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WO2004056991A3 - Nouvelle cible moleculaire de l'angiogenese et utilisations - Google Patents

Nouvelle cible moleculaire de l'angiogenese et utilisations Download PDF

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Publication number
WO2004056991A3
WO2004056991A3 PCT/FR2003/003776 FR0303776W WO2004056991A3 WO 2004056991 A3 WO2004056991 A3 WO 2004056991A3 FR 0303776 W FR0303776 W FR 0303776W WO 2004056991 A3 WO2004056991 A3 WO 2004056991A3
Authority
WO
WIPO (PCT)
Prior art keywords
concerns
angiogenesis
diagnostic
therapeutic
molecular target
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/FR2003/003776
Other languages
English (en)
Other versions
WO2004056991A2 (fr
Inventor
Fabien Schweighoffer
Silvere Petit
Emmanuel Valentin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ExonHit Therapeutics SA
Original Assignee
ExonHit Therapeutics SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ExonHit Therapeutics SA filed Critical ExonHit Therapeutics SA
Priority to AU2003300656A priority Critical patent/AU2003300656A1/en
Publication of WO2004056991A2 publication Critical patent/WO2004056991A2/fr
Publication of WO2004056991A3 publication Critical patent/WO2004056991A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La présente demande concerne le domaine de la biologie et de la santé. Elle concerne plus particulièrement l'identification et la caractérisation fonctionnelle d'une nouvelle protéine impliquée dans les mécanismes de l'angiogénèse, ainsi que l'utilisation de cette protéine comme cible thérapeutique, diagnostique ou de criblage. Elle porte également sur des outils utilisables pour la mise en oeuvre de méthodes thérapeutiques, diagnostiques ou de criblage, comme notamment des sondes, anticorps, vecteurs, cellules recombinantes, etc. L'invention est particulièrement utile pour la préparation de composés pharmaceutiques dans le domaine des cancers, de l'angiogenèse, des maladies inflammatoires ou des altérations tissulaires.
PCT/FR2003/003776 2002-12-18 2003-12-17 Nouvelle cible moleculaire de l'angiogenese et utilisations Ceased WO2004056991A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003300656A AU2003300656A1 (en) 2002-12-18 2003-12-17 Novel angiogenic molecular target and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR02/16123 2002-12-18
FR0216123A FR2849055A1 (fr) 2002-12-18 2002-12-18 Nouvelle cible moleculaire de l'angiogenese et utilisations

Publications (2)

Publication Number Publication Date
WO2004056991A2 WO2004056991A2 (fr) 2004-07-08
WO2004056991A3 true WO2004056991A3 (fr) 2004-08-26

Family

ID=32406174

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2003/003776 Ceased WO2004056991A2 (fr) 2002-12-18 2003-12-17 Nouvelle cible moleculaire de l'angiogenese et utilisations

Country Status (3)

Country Link
AU (1) AU2003300656A1 (fr)
FR (1) FR2849055A1 (fr)
WO (1) WO2004056991A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005092923A2 (fr) * 2004-03-18 2005-10-06 THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICEOffice of the Technology Transfer, NIH 6011 Executive Boulevard Cytonectine, gene de la cytonectine et inhibiteurs de la cytonectine et ligand de liaison, leur utilisation dans le diagnostic et le traitement de maladies
CN100493609C (zh) * 2005-01-19 2009-06-03 中国医学科学院基础医学研究所 抗恶性肿瘤的药物组合物及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH686761A5 (de) * 1993-05-27 1996-06-28 Sandoz Ag Galenische Formulierungen.
US5989860A (en) * 1997-12-12 1999-11-23 Incyte Pharmaceuticals, Inc. Human isomerase homologs
AU2103399A (en) * 1998-01-09 1999-07-26 Human Genome Sciences, Inc. Human fk506 binding proteins
WO2000029448A2 (fr) * 1998-11-17 2000-05-25 Sagami Chemical Research Center Proteines humaines a domaines hydrophobes et adn codant pour ces proteines
WO2001073024A1 (fr) * 2000-03-31 2001-10-04 Helix Research Institute Agent induisant l'expression du facteur neurotrophique
US6687428B2 (en) * 2000-09-21 2004-02-03 Tera Op (Usa) Inc. Optical switch

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
COSS M C ET AL: "MOLECULAR CLONING, DNA SEQUENCE ANALYSIS, AND BIOCHEMICAL CHARACTERIZATION OF A NOVEL 65-KDA FK506-BINDING PROTEIN (FKBP65)", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, US, vol. 270, no. 49, 8 December 1995 (1995-12-08), pages 2933 - 2941, XP002917765, ISSN: 0021-9258 *
DATABASE EMBL [online] 12 February 2001 (2001-02-12), GENOSCOPE: "3 prime end of clone CS0DK003YI01 of library LTI_NFL006_PL2 from placenta of male Homo sapiens (human)", XP002286120, Database accession no. AL578100 *
DATABASE EMBL [online] 29 September 2000 (2000-09-29), SUGANO S ET AL: "Homo sapiens CDNA, FLJ22221 fis, clone HRC01651", XP002286119, Database accession no. AK025874 *
DATABASE UNIPROT [online] 1 March 2001 (2001-03-01), WATANABE ET AL: "Hypothetical protein FLJ22221", XP002286118, Database accession no. Q9H6J3 *
DAVIS E C ET AL: "IDENTIFICATION OF TROPOELASTIN AS A LIGAND FOR THE 65-KD FK 506-BINDING PROTEIN, FKBP65, IN THE SECRETORY PATHWAY", THE JOURNAL OF CELL BIOLOGY, ROCKEFELLER UNIVERSITY PRESS, US, vol. 140, no. 2, 26 January 1998 (1998-01-26), pages 295 - 303, XP000978504, ISSN: 0021-9525 *
PATTERSON CHARLES E ET AL: "Genomic organization of mouse and human 65 kDa FK506-binding protein genes and evolution of the FKBP multigene family", GENOMICS, vol. 79, no. 6, June 2002 (2002-06-01), pages 881 - 889, XP002286117, ISSN: 0888-7543 *

Also Published As

Publication number Publication date
WO2004056991A2 (fr) 2004-07-08
AU2003300656A1 (en) 2004-07-14
AU2003300656A8 (en) 2004-07-14
FR2849055A1 (fr) 2004-06-25

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