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WO2004050896A8 - A method and therapeutic platelets - Google Patents

A method and therapeutic platelets

Info

Publication number
WO2004050896A8
WO2004050896A8 PCT/US2003/038133 US0338133W WO2004050896A8 WO 2004050896 A8 WO2004050896 A8 WO 2004050896A8 US 0338133 W US0338133 W US 0338133W WO 2004050896 A8 WO2004050896 A8 WO 2004050896A8
Authority
WO
WIPO (PCT)
Prior art keywords
preservative
biological sample
loaded
solution
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2003/038133
Other languages
French (fr)
Other versions
WO2004050896A2 (en
WO2004050896A9 (en
WO2004050896A3 (en
Inventor
John H Crowe
Fern Tablin
Willem Wolkers
Naomi J Walker
Sheri Looper
Nelly M Tsvetkova
Zsolt Torok
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California Berkeley
University of California San Diego UCSD
Original Assignee
University of California Berkeley
University of California San Diego UCSD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/635,333 external-priority patent/US20040136974A1/en
Priority claimed from US10/635,353 external-priority patent/US20050033185A1/en
Application filed by University of California Berkeley, University of California San Diego UCSD filed Critical University of California Berkeley
Priority to AU2003302323A priority Critical patent/AU2003302323A1/en
Publication of WO2004050896A2 publication Critical patent/WO2004050896A2/en
Publication of WO2004050896A8 publication Critical patent/WO2004050896A8/en
Publication of WO2004050896A9 publication Critical patent/WO2004050896A9/en
Anticipated expiration legal-status Critical
Publication of WO2004050896A3 publication Critical patent/WO2004050896A3/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

A method for loading a preservative into a biological sample comprising providing a preservation solution having a preservative, water and protein, and loading a biological sample with the preservative solution to produce a preservative-loaded biological sample having the preservative solution generally including higher glass transition temperature than glass transition temperatures for a preservative solution having the preservative, water and no protein. A process for processing biological samples comprising suspending biological samples in a preservative solution at a concentration greater than about 108 platelets per ml. of preservative solution to produce preservation-loaded biological samples, freeze-drying the perservative-loaded biological samples, and recovering at least 70 % of the freeze-dried biological samples. A biological sample composition comprising a biological sample loaded with a preservative solution having a perservative, water, and protein, and generally further having higher glass transition temperatures than glass transition temperature for the biological sample loaded with the preservative, water, but no protein.
PCT/US2003/038133 2002-11-29 2003-11-28 A method and therapeutic platelets Ceased WO2004050896A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003302323A AU2003302323A1 (en) 2002-11-29 2003-11-28 A method and therapeutic platelets

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US43004002P 2002-11-29 2002-11-29
US60/430,040 2002-11-29
US10/635,333 US20040136974A1 (en) 2002-01-16 2003-08-06 Therapeutic platelets and methods
US10/635,353 2003-08-06
US10/635,333 2003-08-06
US10/635,353 US20050033185A1 (en) 2003-08-06 2003-08-06 Method for correcting vessel and background light intensities used in beer's law for light scattering in tissue

Publications (4)

Publication Number Publication Date
WO2004050896A2 WO2004050896A2 (en) 2004-06-17
WO2004050896A8 true WO2004050896A8 (en) 2004-08-05
WO2004050896A9 WO2004050896A9 (en) 2004-11-25
WO2004050896A3 WO2004050896A3 (en) 2006-12-21

Family

ID=33458679

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/038133 Ceased WO2004050896A2 (en) 2002-11-29 2003-11-28 A method and therapeutic platelets

Country Status (2)

Country Link
AU (1) AU2003302323A1 (en)
WO (1) WO2004050896A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005272821B2 (en) 2004-08-12 2010-09-09 Cellphire, Inc Methods for preparing freeze-dried platelets, compositions comprising freeze-dried platelets, and methods of use
US7811558B2 (en) 2004-08-12 2010-10-12 Cellphire, Inc. Use of stabilized platelets as hemostatic agent
US8097403B2 (en) 2006-12-14 2012-01-17 Cellphire, Inc. Freeze-dried platelets, method of making and method of use as a diagnostic agent
US20200224164A1 (en) 2018-11-30 2020-07-16 Cellphire, Inc. Platelets as delivery agents
EP3886879A4 (en) 2018-11-30 2022-12-07 Cellphire Inc. Platelets as delivery agents
EP3962499A4 (en) 2019-05-03 2023-01-25 Cellphire Inc. MATERIALS AND PROCESSES FOR THE PRODUCTION OF BLOOD PRODUCTS
US11701388B2 (en) 2019-08-16 2023-07-18 Cellphire, Inc. Thrombosomes as an antiplatelet agent reversal agent
US20210308066A1 (en) 2020-02-04 2021-10-07 Cellphire, Inc. Anti-fibrinolytic loaded platelets
US20220273724A1 (en) 2021-02-17 2022-09-01 Cellphire Inc. Freeze-dried platelet derivative compositions for treating antiplatelet induced coagulopathy

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8500698D0 (en) * 1985-01-11 1985-02-13 Unilever Plc Preparation of reagents
GB9916790D0 (en) * 1999-07-16 1999-09-22 Health Lab Service Board Storage of microorganisms,cells and tissue

Also Published As

Publication number Publication date
WO2004050896A2 (en) 2004-06-17
AU2003302323A1 (en) 2004-06-23
WO2004050896A9 (en) 2004-11-25
AU2003302323A8 (en) 2004-06-23
WO2004050896A3 (en) 2006-12-21

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