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WO2004043401A3 - Method of preparing anti-angiogenic drug from cartillage and chondrocytes and methods of use - Google Patents

Method of preparing anti-angiogenic drug from cartillage and chondrocytes and methods of use Download PDF

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Publication number
WO2004043401A3
WO2004043401A3 PCT/US2003/036132 US0336132W WO2004043401A3 WO 2004043401 A3 WO2004043401 A3 WO 2004043401A3 US 0336132 W US0336132 W US 0336132W WO 2004043401 A3 WO2004043401 A3 WO 2004043401A3
Authority
WO
WIPO (PCT)
Prior art keywords
chondrocytes
extract
cartillage
methods
preparing anti
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2003/036132
Other languages
French (fr)
Other versions
WO2004043401A2 (en
Inventor
Kin-Ping Wong
Ming-Chung Wong
Anna Wong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wackvom Ltd
Original Assignee
Wackvom Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wackvom Ltd filed Critical Wackvom Ltd
Priority to AU2003295473A priority Critical patent/AU2003295473A1/en
Publication of WO2004043401A2 publication Critical patent/WO2004043401A2/en
Publication of WO2004043401A3 publication Critical patent/WO2004043401A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5064—Endothelial cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders
    • G01N2800/101—Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
    • G01N2800/102—Arthritis; Rheumatoid arthritis, i.e. inflammation of peripheral joints
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders
    • G01N2800/105—Osteoarthritis, e.g. cartilage alteration, hypertrophy of bone

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

A new anti-angiogenic and anti-inflammatory extract derived from the cartilage of embryonic cartilaginous fish, and a method for producing the extract has been developed. The extract is derived by culturing the chondrocytes from shark or shark embryo. Additionally, a specialized growth media containing serum from the blood of a cartilaginous fish has been developed for culturing the chondrocytes to produce the extract.
PCT/US2003/036132 2002-11-13 2003-11-13 Method of preparing anti-angiogenic drug from cartillage and chondrocytes and methods of use Ceased WO2004043401A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003295473A AU2003295473A1 (en) 2002-11-13 2003-11-13 Method of preparing anti-angiogenic drug from cartillage and chondrocytes and methods of use

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42625802P 2002-11-13 2002-11-13
US60/426,258 2002-11-13

Publications (2)

Publication Number Publication Date
WO2004043401A2 WO2004043401A2 (en) 2004-05-27
WO2004043401A3 true WO2004043401A3 (en) 2004-09-30

Family

ID=32313127

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/036132 Ceased WO2004043401A2 (en) 2002-11-13 2003-11-13 Method of preparing anti-angiogenic drug from cartillage and chondrocytes and methods of use

Country Status (3)

Country Link
AU (1) AU2003295473A1 (en)
TW (1) TW200423951A (en)
WO (1) WO2004043401A2 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20051572A1 (en) * 2005-08-12 2007-02-13 Alberto Astaldi PHARMACEUTICAL COMPOSITION CONTAINING AS AN ACTIVE SUBSTANCE A PROTEIN FRACTION EXTRACTED FROM EMBRYOS OF OVIPARIANS IN THE PERIOD OF CELLULAR DIFFERENTIATION AND RELATIVE PREPARATION PROCESS
US20100111910A1 (en) * 2006-07-12 2010-05-06 Angioblast Systems, Inc. Treatment of excessive neovascularization
AU2007201520A1 (en) * 2006-11-29 2008-06-12 Neville Trevor Wittenbaker Comosition for the treatment of patients with kidney stones, gout - and arthritis
US9321993B2 (en) 2010-06-17 2016-04-26 The Trustees Of Columbia University In The City Of New York Tissue culture method for producing cartilage using trimethylamine N-oxide and chondroitinase
WO2014038864A1 (en) * 2012-09-05 2014-03-13 아주대학교산학협력단 Composition for preventing and treating immune disease using human fetal cartilage-derived cells
JP7654240B2 (en) 2017-09-19 2025-04-01 マサチューセッツ インスティテュート オブ テクノロジー Compositions and uses thereof for chimeric antigen receptor t cell therapy
CN108939043A (en) * 2018-08-27 2018-12-07 车路平 A kind of Shark cartilage glycoprotein and its anticancer purpose
AU2019346335B2 (en) 2018-09-28 2024-07-25 Massachusetts Institute Of Technology Collagen-localized immunomodulatory molecules and methods thereof
EP3990491A1 (en) 2019-06-26 2022-05-04 Massachusetts Institute of Technology Immunomodulatory fusion protein-metal hydroxide complexes and methods thereof
WO2021061648A1 (en) 2019-09-23 2021-04-01 Massachusetts Institute Of Technology Methods and compositions for stimulation of endogenous t cell responses
JP2023517889A (en) 2020-03-10 2023-04-27 マサチューセッツ インスティテュート オブ テクノロジー Compositions and methods for immunotherapy of NPM1c-positive cancers
CA3173527A1 (en) 2020-03-10 2021-09-16 Massachusetts Institute Of Technology Methods for generating engineered memory-like nk cells and compositions thereof
US12433954B2 (en) 2020-05-01 2025-10-07 Massachusetts Institute Of Technology Methods of activating anti-CD19 chimeric antigen receptor (CAR) T cells using amphiphilic ligand conjugates comprising CAR-targeting protein sequence motifs
WO2023081715A1 (en) 2021-11-03 2023-05-11 Viracta Therapeutics, Inc. Combination of car t-cell therapy with btk inhibitors and methods of use thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5401653A (en) * 1994-02-23 1995-03-28 Sea Run Holdings, Inc. Method for culturing insect cells in a medium containing fish serum
WO2001078674A1 (en) * 2000-04-18 2001-10-25 Ceteris Holding B.V. -Amsterdam (Olanda)- Succursale Di Lugano A composition based on natural extracts useful in the prevention and treatment of cutaneous wrinkles

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5401653A (en) * 1994-02-23 1995-03-28 Sea Run Holdings, Inc. Method for culturing insect cells in a medium containing fish serum
WO2001078674A1 (en) * 2000-04-18 2001-10-25 Ceteris Holding B.V. -Amsterdam (Olanda)- Succursale Di Lugano A composition based on natural extracts useful in the prevention and treatment of cutaneous wrinkles

Also Published As

Publication number Publication date
TW200423951A (en) 2004-11-16
WO2004043401A2 (en) 2004-05-27
AU2003295473A1 (en) 2004-06-03
AU2003295473A8 (en) 2004-06-03

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