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WO2003105561A3 - Method and devices for diagnosing and treating choroid plexus failure - Google Patents

Method and devices for diagnosing and treating choroid plexus failure Download PDF

Info

Publication number
WO2003105561A3
WO2003105561A3 PCT/US2003/018885 US0318885W WO03105561A3 WO 2003105561 A3 WO2003105561 A3 WO 2003105561A3 US 0318885 W US0318885 W US 0318885W WO 03105561 A3 WO03105561 A3 WO 03105561A3
Authority
WO
WIPO (PCT)
Prior art keywords
failure
diagnosing
devices
choroid plexus
level
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2003/018885
Other languages
French (fr)
Other versions
WO2003105561A2 (en
Inventor
Edward Rubenstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alavita Pharmaceuticals Inc
Original Assignee
Surromed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Surromed Inc filed Critical Surromed Inc
Publication of WO2003105561A2 publication Critical patent/WO2003105561A2/en
Publication of WO2003105561A3 publication Critical patent/WO2003105561A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pathology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Choroid plexus failure in a subject is diagnosed and treated by measuring the level of one or more components of cerebrospinal fluid, comparing the level to a desired level, and adjusting the level toward the desired level. Treatment can occur using an implantable device.
PCT/US2003/018885 2002-06-12 2003-06-12 Method and devices for diagnosing and treating choroid plexus failure Ceased WO2003105561A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US38832902P 2002-06-12 2002-06-12
US60/388,329 2002-06-12
US39086602P 2002-06-20 2002-06-20
US60/390,866 2002-06-20

Publications (2)

Publication Number Publication Date
WO2003105561A2 WO2003105561A2 (en) 2003-12-24
WO2003105561A3 true WO2003105561A3 (en) 2004-09-23

Family

ID=29740011

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/018885 Ceased WO2003105561A2 (en) 2002-06-12 2003-06-12 Method and devices for diagnosing and treating choroid plexus failure

Country Status (2)

Country Link
US (1) US20030233035A1 (en)
WO (1) WO2003105561A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9335331B2 (en) * 2005-04-11 2016-05-10 Cornell Research Foundation, Inc. Multiplexed biomarkers for monitoring the Alzheimer's disease state of a subject
EA201270160A1 (en) 2009-07-10 2012-07-30 Линзи О. Скотт Iii METHODS AND COMPOSITIONS FOR THE TREATMENT OF MEDICAL CONDITIONS ASSOCIATED WITH THE THYROID GLAND USING RESTORED FOLATES
CN103235115B (en) * 2013-04-01 2015-04-01 上海师范大学 Novel electrochemiluminescence immunosensor for rapid and high sensitive detection of retinol binding protein and its preparation method
HUE049036T2 (en) * 2015-04-17 2020-09-28 P&X Medical Nv Compositions and tools for treating glaucoma

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4761158A (en) * 1984-03-16 1988-08-02 Pudenz-Schulte Medical Research Corp. Subcutaneous infusion reservoir and pump system
US5545566A (en) * 1992-10-09 1996-08-13 Massachusetts Institute Of Technology Antemortem diagnostic test for alzheimer's disease
US5866547A (en) * 1998-01-20 1999-02-02 Beth Israel Deaconess Medical Center Methods of neuroendocrine regulation of affective disorders
US6114133A (en) * 1994-11-14 2000-09-05 Elan Pharmaceuticals, Inc. Methods for aiding in the diagnosis of Alzheimer's disease by measuring amyloid-β peptide (x-≧41)
WO2000066188A2 (en) * 1999-04-30 2000-11-09 Diatranz Limited Xenotransplant for cns therapy

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4761158A (en) * 1984-03-16 1988-08-02 Pudenz-Schulte Medical Research Corp. Subcutaneous infusion reservoir and pump system
US5545566A (en) * 1992-10-09 1996-08-13 Massachusetts Institute Of Technology Antemortem diagnostic test for alzheimer's disease
US6114133A (en) * 1994-11-14 2000-09-05 Elan Pharmaceuticals, Inc. Methods for aiding in the diagnosis of Alzheimer's disease by measuring amyloid-β peptide (x-≧41)
US5866547A (en) * 1998-01-20 1999-02-02 Beth Israel Deaconess Medical Center Methods of neuroendocrine regulation of affective disorders
WO2000066188A2 (en) * 1999-04-30 2000-11-09 Diatranz Limited Xenotransplant for cns therapy

Also Published As

Publication number Publication date
WO2003105561A2 (en) 2003-12-24
US20030233035A1 (en) 2003-12-18

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