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WO2003101462A3 - Utilisation de derives d'acide biphosphonique pour le traitement de maladies associees au depot de diphosphate de calcium et traitement dentaire - Google Patents

Utilisation de derives d'acide biphosphonique pour le traitement de maladies associees au depot de diphosphate de calcium et traitement dentaire Download PDF

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Publication number
WO2003101462A3
WO2003101462A3 PCT/DK2003/000361 DK0300361W WO03101462A3 WO 2003101462 A3 WO2003101462 A3 WO 2003101462A3 DK 0300361 W DK0300361 W DK 0300361W WO 03101462 A3 WO03101462 A3 WO 03101462A3
Authority
WO
WIPO (PCT)
Prior art keywords
treatment
acid derivatives
bisphosphonic acid
calcium
phrophosphated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/DK2003/000361
Other languages
English (en)
Other versions
WO2003101462A2 (fr
Inventor
Joergen Christoffersen
Margaret Ruth Christoffersen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Københavns Universitet
Original Assignee
Københavns Universitet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Københavns Universitet filed Critical Københavns Universitet
Priority to EP03724904A priority Critical patent/EP1536803A2/fr
Priority to AU2003227524A priority patent/AU2003227524A1/en
Publication of WO2003101462A2 publication Critical patent/WO2003101462A2/fr
Publication of WO2003101462A3 publication Critical patent/WO2003101462A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des dérivés d'acide bisphosphonique, ainsi que leurs sels et leurs hydrates, pour la préparation d'un médicament pour le traitement de maladies associées au dépôt de diphosphate de calcium, telle que la pseudo-goutte et la chondrocalcinose. L'invention concerne de plus l'utilisation desdits dérivés de bisphosphonate pour la fabrication d'une obturation dentaire ou d'un médicament de prévention ou de traitement des caries dentaires. L'invention concerne également des compositions utilisées pour retarder le dépôt de disphosphate de calcium, par exemple dans les interstices, et pour traiter ou empêcher l'apparition de cavités dans la dent.
PCT/DK2003/000361 2002-05-31 2003-06-02 Utilisation de derives d'acide biphosphonique pour le traitement de maladies associees au depot de diphosphate de calcium et traitement dentaire Ceased WO2003101462A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP03724904A EP1536803A2 (fr) 2002-05-31 2003-06-02 Utilisation de derives d'acide biphosphonique pour le traitement de maladies associees au depot de diphosphate de calcium et traitement dentaire
AU2003227524A AU2003227524A1 (en) 2002-05-31 2003-06-02 Use of bisphosphonic acid derivatives for the treatment of calcium phrophosphated deposition disease and dental treatment

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DKPA200200842 2002-05-31
DKPA200200842 2002-05-31
DKPA200201325 2002-09-09
DKPA200201325 2002-09-09

Publications (2)

Publication Number Publication Date
WO2003101462A2 WO2003101462A2 (fr) 2003-12-11
WO2003101462A3 true WO2003101462A3 (fr) 2004-01-29

Family

ID=29713302

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DK2003/000361 Ceased WO2003101462A2 (fr) 2002-05-31 2003-06-02 Utilisation de derives d'acide biphosphonique pour le traitement de maladies associees au depot de diphosphate de calcium et traitement dentaire

Country Status (3)

Country Link
EP (1) EP1536803A2 (fr)
AU (1) AU2003227524A1 (fr)
WO (1) WO2003101462A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1958649A1 (fr) * 2007-02-14 2008-08-20 Graftys Ciment calcium-phosphate injectable libérant un inhibiteur de la résorption osseuse
EP3284456B1 (fr) * 2016-08-15 2024-06-05 smartodont GmbH Sels de phosphonate solide comme module d'extension pour l'endodontie
DE102016013737A1 (de) 2016-11-17 2018-05-17 WindplusSonne GmbH Hexahydroxycyclohexanhexaphosphorsäureestersalze zur Behandlung von Kalzinose sowie diätische Lebensmittel mit Hexahydroxycyclohexanhexaphosphorsäureestersalzen als Zusatzstoffe

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3959458A (en) * 1973-02-09 1976-05-25 The Procter & Gamble Company Oral compositions for calculus retardation
US4814326A (en) * 1985-05-24 1989-03-21 Istituto Gentili S.P.A. Pharmaceutical compositions based on diphosphonates for the treatment of arthrosis and osteoarthritis
US4973576A (en) * 1987-03-10 1990-11-27 Yamanouchi Pharmaceutical Co., Ltd. Bisphophonic acid derivatives and pharmaceutical compositions containing the same
US5220021A (en) * 1989-04-03 1993-06-15 The Upjohn Company Geminal bisphosphonic acids and derivatives as anti-arthritic agents

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3959458A (en) * 1973-02-09 1976-05-25 The Procter & Gamble Company Oral compositions for calculus retardation
US4814326A (en) * 1985-05-24 1989-03-21 Istituto Gentili S.P.A. Pharmaceutical compositions based on diphosphonates for the treatment of arthrosis and osteoarthritis
US4973576A (en) * 1987-03-10 1990-11-27 Yamanouchi Pharmaceutical Co., Ltd. Bisphophonic acid derivatives and pharmaceutical compositions containing the same
US5220021A (en) * 1989-04-03 1993-06-15 The Upjohn Company Geminal bisphosphonic acids and derivatives as anti-arthritic agents

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
OFELIA MUNIZ ET AL: "NTP Pyrophosphohydrolase in human chondrocalcinotic and osteoarthritic cartilage", ARTHRITIS AND RHEUMATISM, vol. 27, no. 2, February 1984 (1984-02-01), pages 186 - 192, XP002252854 *

Also Published As

Publication number Publication date
AU2003227524A1 (en) 2003-12-19
WO2003101462A2 (fr) 2003-12-11
EP1536803A2 (fr) 2005-06-08

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