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WO2003037263A2 - Sunspot skin cream - Google Patents

Sunspot skin cream Download PDF

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Publication number
WO2003037263A2
WO2003037263A2 PCT/US2002/034661 US0234661W WO03037263A2 WO 2003037263 A2 WO2003037263 A2 WO 2003037263A2 US 0234661 W US0234661 W US 0234661W WO 03037263 A2 WO03037263 A2 WO 03037263A2
Authority
WO
WIPO (PCT)
Prior art keywords
composition
sulfur
topical composition
carrier vehicle
weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2002/034661
Other languages
French (fr)
Other versions
WO2003037263A3 (en
Inventor
Brian Penick
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to AU2002342190A priority Critical patent/AU2002342190A1/en
Publication of WO2003037263A2 publication Critical patent/WO2003037263A2/en
Publication of WO2003037263A3 publication Critical patent/WO2003037263A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/925Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/23Sulfur; Selenium; Tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31Hydrocarbons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin

Definitions

  • Tinea versicolor is a very common skin condition, especially in sub tropical regions.
  • Tinea versicolor is caused by the yeast pityrosporon orbiculare. People who have tinea versicolor are genetically predisposed to developing a rash when this germ is present on the skin. When the yeast grows on untanned shin, the rash is pink to brown. When the yeast grows on tanned skin, the rash looks white because the yeast blocks out the sunlight and the skin where the yeast is growing does not tan. When growing on Asian or African-American skin, the rash can look darker or lighter than the surrounding skin depending on the patient. Conventional treatments of tinea versicolor are commonly ineffective. Oral ketaconazole may be prescribed in doses of 200 g daily for 2 to 4 weeks.
  • Selsun Shampoo sodium sulfide
  • Selsun Shampoo is applied to the affected areas before bed and washed off the next morning. This procedure is repeated for several days.
  • Some treatments make use of Lamasil (terbinafine hydrochloride) as a pill or as a topical solution. As a topical solution, Lamasil must be applied several times per day for several weeks and even then may be an ineffective treatment.
  • the use of oral medication is undesired as well, because the oral medications conventionally prescribed for these skin disorders have side effects and do not offer a permanent solution to the problem. Needs exist for a safe and efficient treatment of skin irritations such as tinea versicolor and sebhorrheic keratosis.
  • the present invention is an effective alternative to conventional treatments of tinea versicolor.
  • the present skin cream may be used to treat skin conditions including, but not limited to, tinea versicolor and sebhorrheic keratosis.
  • the skin cream preferably requires one application, unless the condition is severe, to cure the condition.
  • conventional treatments require daily and multi-daily regimens for days or months making them expensive and ineffective if a strict regimen is not followed.
  • the present invention uses sublimed sulfur in a greater percentage than is currently used in any conventional treatment.
  • Conventional treatments expressly avoid excessive sulfur content and advocate minimal amounts of sulfur to be used in the creams and lotions.
  • the skin cream mixture or composition is topically applied to the irritated skin and is generally effective in treating the skin disorder after one application.
  • the cream may generally be applied after the subject showers and before bedtime. The cream is applied to all affected areas. Upon waking, the subject showers to remove any excess residual cream.
  • the present invention when applied topically, is effective in treating many different skin disorders, but in particular is significantly effective in treating tinea versicolor (sunspots) and seborrheic keratoses.
  • the present invention includes a composition having a vehicle or carrier and sulfur.
  • the mixture or composition comprises approximately equal parts of the carrier vehicle and sulfur in the absence of water.
  • the carrier vehicle includes, but is not limited to, Vaseline, petroleum jelly, or lard or any similar component or combinations thereof, with the same overall end effect.
  • the important component is the sulfur in the composition.
  • the sulfur is combined with the carrier, such as Vaseline, in a ratio in which the sulfur is greater than the carrier.
  • the preferred skin cream is applied directly to the skin to cure skin irritations, dermatitis, and diseases such as, but not limited to, tinea versicolor (sunspots) and seborrheic keratoses.
  • the skin cream may be in any form suitable for topical application such as, but not limited to, gels, creams, lotions, ointments, powders, pastes, sprays or the like.
  • a preferred method of treating skin conditions includes preparing the composition, preferably as a non-aqueous topical application composition by mixing sulfur and a carrier vehicle, and applying the topical composition to areas of interest on the skin for treating skin conditions.
  • the sulfur and the carrier vehicle are mixed together, such that the percent by weight of sulfur is greater than the percent by weight of the carrier vehicle.
  • the sulfur may be in the form of sublimed sulfur and the carrier vehicle may include, but is not limited to, Vaseline, lard, petroleum jelly, etc.
  • the composition may be prepared for use as a topical application and may be in any suitable form such as, but not limited to, lotions, creams, ointments, powders, gels, pastes, sprays, and combinations thereof.
  • lotions, creams, ointments, powders, gels, pastes, sprays, and combinations thereof The following exemplify various compositions of the inventive skin cream:

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

A composition for treating skin conditions includes sulfur combined with a carrier vehicle such as, Vaseline, petroleum jelly, lard or the like. At least fifty % by weight of the sulfur is used in combination with the Vaseline, petroleum jelly or lard to create an effective skin cream for curing skin conditions such as, tinea versicolor, sebhorrheic keratosis and other kind of dermatitis. The skin cream generally requires one application, unless the condition is severe, thereby avoiding daily and multi-daily expensive regimens.

Description

SUNSPOT SKIN CREAM BACKGROUND OF THE INVENTION
Tinea versicolor is a very common skin condition, especially in sub tropical regions.
It appears as a patch or patches of white, brown or light pink, finely flaking skin. This condition can get worse enough to cover the entire upper body including the face, sometimes causing itching and burning.
Tinea versicolor is caused by the yeast pityrosporon orbiculare. People who have tinea versicolor are genetically predisposed to developing a rash when this germ is present on the skin. When the yeast grows on untanned shin, the rash is pink to brown. When the yeast grows on tanned skin, the rash looks white because the yeast blocks out the sunlight and the skin where the yeast is growing does not tan. When growing on Asian or African-American skin, the rash can look darker or lighter than the surrounding skin depending on the patient. Conventional treatments of tinea versicolor are commonly ineffective. Oral ketaconazole may be prescribed in doses of 200 g daily for 2 to 4 weeks. Various treatment regimes utilizing oral ketaconazole have been reported to be effective in preventing relapse, but such regimens may not be as effective as reported. This oral prescription has many side effects and past history of liver disease and abnormal liver function test are relative contraindications. Fulminating hepatitis has been reported to be associated with oral ketaconazole and it thus should not be used to treat the skin infection tinea versicolor.
Another conventional treatment is through the use of Selsun Shampoo (selenium sulfide). Selsun Shampoo is applied to the affected areas before bed and washed off the next morning. This procedure is repeated for several days. Some treatments make use of Lamasil (terbinafine hydrochloride) as a pill or as a topical solution. As a topical solution, Lamasil must be applied several times per day for several weeks and even then may be an ineffective treatment. The use of oral medication is undesired as well, because the oral medications conventionally prescribed for these skin disorders have side effects and do not offer a permanent solution to the problem. Needs exist for a safe and efficient treatment of skin irritations such as tinea versicolor and sebhorrheic keratosis. SUMMARY OF THE INVENTION
The present invention is an effective alternative to conventional treatments of tinea versicolor. The present skin cream may be used to treat skin conditions including, but not limited to, tinea versicolor and sebhorrheic keratosis. The skin cream preferably requires one application, unless the condition is severe, to cure the condition. In contrast, conventional treatments require daily and multi-daily regimens for days or months making them expensive and ineffective if a strict regimen is not followed.
The present invention uses sublimed sulfur in a greater percentage than is currently used in any conventional treatment. Conventional treatments expressly avoid excessive sulfur content and advocate minimal amounts of sulfur to be used in the creams and lotions.
In a preferred embodiment, the skin cream mixture or composition is topically applied to the irritated skin and is generally effective in treating the skin disorder after one application. The cream may generally be applied after the subject showers and before bedtime. The cream is applied to all affected areas. Upon waking, the subject showers to remove any excess residual cream.
The present invention, when applied topically, is effective in treating many different skin disorders, but in particular is significantly effective in treating tinea versicolor (sunspots) and seborrheic keratoses. These and further and other objects and features of the invention are apparent in the disclosure, which includes the above and ongoing written specification, with the claims and the drawings.
DETAILED DESCRIPTION OF PREFERRED EMBODIMENTS
In a preferred embodiment the present invention includes a composition having a vehicle or carrier and sulfur. Preferably, the mixture or composition comprises approximately equal parts of the carrier vehicle and sulfur in the absence of water.
Preferably, equal parts of sublimed sulfur and the carrier vehicle, i.e. in ratios of I 1, are used to form the cream. The carrier vehicle includes, but is not limited to, Vaseline, petroleum jelly, or lard or any similar component or combinations thereof, with the same overall end effect. The important component is the sulfur in the composition.
In another preferred embodiment, the sulfur is combined with the carrier, such as Vaseline, in a ratio in which the sulfur is greater than the carrier.
The preferred skin cream is applied directly to the skin to cure skin irritations, dermatitis, and diseases such as, but not limited to, tinea versicolor (sunspots) and seborrheic keratoses. The skin cream may be in any form suitable for topical application such as, but not limited to, gels, creams, lotions, ointments, powders, pastes, sprays or the like.
A preferred method of treating skin conditions includes preparing the composition, preferably as a non-aqueous topical application composition by mixing sulfur and a carrier vehicle, and applying the topical composition to areas of interest on the skin for treating skin conditions. Preferably, equal percents by weight of the sulfur and the carrier vehicle are mixed together, such that the percent by weight of sulfur is greater than the percent by weight of the carrier vehicle.
The sulfur may be in the form of sublimed sulfur and the carrier vehicle may include, but is not limited to, Vaseline, lard, petroleum jelly, etc. The composition may be prepared for use as a topical application and may be in any suitable form such as, but not limited to, lotions, creams, ointments, powders, gels, pastes, sprays, and combinations thereof. The following exemplify various compositions of the inventive skin cream:
EXAMPLE 1:
Sulfur 50-100 % wt. or % vol.
Carrier 50-greater than 0% wt. or % vol
EXAMPLE 2:
Sulfur 50-100 % wt. or % vol.
Vaseline 50-greater than 0% wt. or % vol
EXAMPLE 3:
Sulfur 50-100 % wt.
Petroleum Jelly 50-greater than 0% wt. or % vol EXAMPLE 4: Sulfur 50-100 % wt. or % vol.
Lard 50-greater than 0% wt. or % vol.
While the invention has been described with reference to specific embodiments, modifications and variations of the invention may be constructed without departing from the scope of the invention, which is defined in the following claims.

Claims

CLAIMS I claim:
1. A topical composition for treatment of skin conditions comprising, sulfur and a carrier vehicle, wherein a weight percent of the sulfur is at least equal to or greater than a weight percent of the carrier vehicle.
2. The topical composition of claim 1, wherein the sulfur is sublimed sulfur.
3. The topical composition of claim 1, wherein the carrier vehicle is Vaseline.
4. The topical composition of claim 1 , wherein the carrier vehicle is petroleum jelly.
5. The topical composition of claim 1 , wherein the carrier vehicle is lard.
6. The topical composition of claim 1 , wherein the composition is a lotion.
7. The topical composition of claim 1 , wherein the composition is a cream.
8. The topical composition of claim 1, wherein the composition is an ointment.
9. The topical composition of claim 1, wherein the composition is a powder.
10. The topical composition of claim 1 , wherein the composition is a gel.
1 1. The topical composition of claim 1, wherein the composition is a paste.
12. The topical composition of claim 1, wherein the composition comprises at least about fifty percent by weight sulfur.
13. The topical composition of claim I, wherein the composition comprises at least about sixty percent by weight sulfur.
14. The topical composition of claim 1 , wherein the composition comprises at least about seventy percent by weight sulfur.
15. The topical composition of claim 1 , wherein the composition comprises at least about eighty percent by weight sulfur.
16. The topical composition of claim 1 , wherein the composition comprises at least ninety percent by weight sulfur.
17. The topical composition of claim 1 , wherein the composition comprises about 50- 100 percent by weight sulfur.
18. The topical composition of claim 1 , wherein the composition is non-aqueous.
19. A method of treating skin conditions comprising preparing a non-aqueous composition by mixing sulfur and a carrier vehicle, and applying the topical composition to areas of interest on the skin for treating skin conditions.
20. The method of claim 19, wherein the mixing comprises mixing equal percents by weight of the sulfur and the carrier vehicle.
21. The method of claim 19, wherein the mixing comprises mixing a percent by weight of sulfur greater than a percent by weight of the carrier vehicle.
22. The method of claim 19, wherein the treating comprises treating dermatitis.
23. The method of claim 19, wherein the treating comprises treating skin conditions selected from a group consisting of tinea versicolor or sunspots and seborrheic keratoses.
24. The method of claim 19, wherein the mixing comprises mixing sublimed sulfur with the carrier vehicle.
25. The method of claim 19, wherein the mixing comprises selecting the carrier vehicle from a group consisting of Vaseline, lard, petroleumjelly, and combinations thereof.
26. The method of claim 19, wherein preparing the composition comprises preparing a composition for topical application selected from the group consisting of lotions, creams, ointments, powders, gels, pastes, sprays, and combinations thereof.
PCT/US2002/034661 2001-10-29 2002-10-29 Sunspot skin cream Ceased WO2003037263A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002342190A AU2002342190A1 (en) 2001-10-29 2002-10-29 Sunspot skin cream

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3703301A 2001-10-29 2001-10-29
US10/037,033 2001-10-29

Publications (2)

Publication Number Publication Date
WO2003037263A2 true WO2003037263A2 (en) 2003-05-08
WO2003037263A3 WO2003037263A3 (en) 2003-07-24

Family

ID=21892082

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/034661 Ceased WO2003037263A2 (en) 2001-10-29 2002-10-29 Sunspot skin cream

Country Status (2)

Country Link
AU (1) AU2002342190A1 (en)
WO (1) WO2003037263A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1696938A1 (en) * 2003-12-23 2006-09-06 Abdalla Magd Ahmed Kotb Element sulfur as an oral or parental medical product

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1213050B (en) * 1986-03-14 1989-12-07 Schiena Ricerche TOPICAL PHARMACEUTICAL COMPOSITIONS IN ODONTOSTOMATOLOGY CONTAINING ALLANTOIN AND ELEMENTAL SULFUR
US5632975A (en) * 1995-03-09 1997-05-27 Earles; R. Martin Composition and method for treatment of dermatitis on the scalp
US5716606A (en) * 1995-08-24 1998-02-10 Boyce; Reginald D. Lotion-based sulfur preparation for skin treatment
US5997892A (en) * 1997-10-09 1999-12-07 Camp; Gary Don Topical therapeutic composition for and method of treating psoriasis

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1696938A1 (en) * 2003-12-23 2006-09-06 Abdalla Magd Ahmed Kotb Element sulfur as an oral or parental medical product

Also Published As

Publication number Publication date
AU2002342190A1 (en) 2003-05-12
WO2003037263A3 (en) 2003-07-24

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