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WO2003035844A3 - Novel histone methyltransferase and methods of its use - Google Patents

Novel histone methyltransferase and methods of its use Download PDF

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Publication number
WO2003035844A3
WO2003035844A3 PCT/US2002/034321 US0234321W WO03035844A3 WO 2003035844 A3 WO2003035844 A3 WO 2003035844A3 US 0234321 W US0234321 W US 0234321W WO 03035844 A3 WO03035844 A3 WO 03035844A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
histone methyltransferase
novel histone
histone
molecules
Prior art date
Application number
PCT/US2002/034321
Other languages
French (fr)
Other versions
WO2003035844A9 (en
WO2003035844A2 (en
Inventor
Eric U Selker
Hisashi Tamaru
Original Assignee
Oregon State
Eric U Selker
Hisashi Tamaru
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oregon State, Eric U Selker, Hisashi Tamaru filed Critical Oregon State
Priority to AU2002360303A priority Critical patent/AU2002360303A1/en
Publication of WO2003035844A2 publication Critical patent/WO2003035844A2/en
Publication of WO2003035844A3 publication Critical patent/WO2003035844A3/en
Publication of WO2003035844A9 publication Critical patent/WO2003035844A9/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
    • C12N9/1007—Methyltransferases (general) (2.1.1.)

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Disclosed herein is a novel histone methyltransferase and nucleic acid molecules encoding it, as well as variants of these molecules. Also provided are methods of using these molecules to influence histone methylation and/or DNA methylation, as well as methods of screening for compounds that influence histone and/or DNA methylation. This disclosure also provides various kits.
PCT/US2002/034321 2001-10-25 2002-10-25 Novel histone methyltransferase and methods of its use WO2003035844A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002360303A AU2002360303A1 (en) 2001-10-25 2002-10-25 Novel histone methyltransferase and methods of its use

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34750601P 2001-10-25 2001-10-25
US60/347,506 2001-10-25

Publications (3)

Publication Number Publication Date
WO2003035844A2 WO2003035844A2 (en) 2003-05-01
WO2003035844A3 true WO2003035844A3 (en) 2003-12-31
WO2003035844A9 WO2003035844A9 (en) 2004-05-13

Family

ID=23363974

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/034321 WO2003035844A2 (en) 2001-10-25 2002-10-25 Novel histone methyltransferase and methods of its use

Country Status (2)

Country Link
AU (1) AU2002360303A1 (en)
WO (1) WO2003035844A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0301450D0 (en) * 2003-01-22 2003-02-19 Medical Res Council Protein crystal structure
CN100577800C (en) * 2007-01-29 2010-01-06 中国科学院遗传与发育生物学研究所 A kind of histone methyltransferase and its coding gene and application
FR3128470A1 (en) * 2021-10-22 2023-04-28 IFP Energies Nouvelles HIGH PROTEIN MUSHROOM STRAINS

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020039776A1 (en) * 2000-06-09 2002-04-04 Thomas Jenuwein Mammalian SUV39H2 proteins and isolated DNA molecules encoding them

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020039776A1 (en) * 2000-06-09 2002-04-04 Thomas Jenuwein Mammalian SUV39H2 proteins and isolated DNA molecules encoding them

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BLOOD, vol. 96, no. 11, PART 1, 16 November 2000 (2000-11-16), pages 159A *
CORY ET AL.: "Inhibitors of histone methylation", CHEMICO-BIOLOGICAL INTERACTIONS, vol. 9, no. 4, 1974, pages 253 - 259, XP002970725 *
DATABASE BIOSIS [online] LEVESQUE ET AL.: "Cytokine regulation of inducible nitric oxide synthase (NOS2) and NOS2 inhibitor-induced apoptosis and death in chronic lymphocytic leukemia cells", XP002970726, accession no. STN Database accession no. 2001:311668 *

Also Published As

Publication number Publication date
WO2003035844A9 (en) 2004-05-13
AU2002360303A1 (en) 2003-05-06
WO2003035844A2 (en) 2003-05-01

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