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WO2003032917A3 - Hookworm vaccine - Google Patents

Hookworm vaccine Download PDF

Info

Publication number
WO2003032917A3
WO2003032917A3 PCT/US2002/033106 US0233106W WO03032917A3 WO 2003032917 A3 WO2003032917 A3 WO 2003032917A3 US 0233106 W US0233106 W US 0233106W WO 03032917 A3 WO03032917 A3 WO 03032917A3
Authority
WO
WIPO (PCT)
Prior art keywords
hookworm
vaccine
hookworm vaccine
uitilized
elicit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2002/033106
Other languages
French (fr)
Other versions
WO2003032917A2 (en
Inventor
Peter Hotez
James Ashcom
Mahnaz Bdamchian
Bin Zhan
Yan Wang
John Hawdon
Alexander Loukas
Angela Williamson
Brian Jones
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
George Washington University
Original Assignee
George Washington University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by George Washington University filed Critical George Washington University
Priority to AU2002335061A priority Critical patent/AU2002335061A1/en
Priority to BRPI0213656-2A priority patent/BR0213656A/en
Publication of WO2003032917A2 publication Critical patent/WO2003032917A2/en
Publication of WO2003032917A3 publication Critical patent/WO2003032917A3/en
Priority to US10/825,692 priority patent/US7303752B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0003—Invertebrate antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Preparations which elicit an immune response to hookworm antigens and which may be uitilized as hookworm vaccines are provided. In addition, a method of increasing the effectiveness of vaccinations against infectious diseases in patients infected with hookworm is provided. The method involves chemically treating the hookworm infestation prior to administering the vaccine.
PCT/US2002/033106 2001-10-17 2002-10-17 Hookworm vaccine Ceased WO2003032917A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2002335061A AU2002335061A1 (en) 2001-10-17 2002-10-17 Hookworm vaccine
BRPI0213656-2A BR0213656A (en) 2001-10-17 2002-10-17 composition, method for obtaining an immune response to tapeworm, method for vaccinating a mammal against tapeworm, vaccine, method for allowing vaccination, methods for reducing blood loss, reducing tapeworm size and reducing distress by tapeworm in a patient infected with tapeworm, synthetic recombinant antigen and antigen
US10/825,692 US7303752B2 (en) 2001-10-17 2004-04-16 Hookworm vaccine

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US32953301P 2001-10-17 2001-10-17
US60/329,533 2001-10-17
US33200701P 2001-11-23 2001-11-23
US60/332,007 2001-11-23
US37540402P 2002-04-26 2002-04-26
US60/375,404 2002-04-26

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US10/825,692 Continuation-In-Part US7303752B2 (en) 2001-10-17 2004-04-16 Hookworm vaccine

Publications (2)

Publication Number Publication Date
WO2003032917A2 WO2003032917A2 (en) 2003-04-24
WO2003032917A3 true WO2003032917A3 (en) 2003-10-23

Family

ID=27406669

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/033106 Ceased WO2003032917A2 (en) 2001-10-17 2002-10-17 Hookworm vaccine

Country Status (4)

Country Link
CN (1) CN1571677A (en)
AU (1) AU2002335061A1 (en)
BR (1) BR0213656A (en)
WO (1) WO2003032917A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9239326B2 (en) 2007-06-15 2016-01-19 Idexx Laboratories, Inc. Compositions, devices, kits and methods for detecting hookworm
US9063129B2 (en) 2007-06-15 2015-06-23 Idexx Laboratories, Inc. Device, kit and method for hookworm antigen capture and detection
CA2724717C (en) 2008-05-19 2018-06-19 Idexx Laboratories, Inc. Methods, devices, kits and compositions for detecting roundworm
WO2009143081A2 (en) 2008-05-19 2009-11-26 Idexx Laboratories, Inc. Methods, devices kits and compositions for detecting roundworm
US7993862B2 (en) 2008-05-19 2011-08-09 Idexx Laboratories, Inc. Methods, devices, kits and compositions for detecting roundworm
WO2009143067A2 (en) 2008-05-19 2009-11-26 Idexx Laboratories, Inc. Methods, devices, kits and compositions for detecting whipworm
ES2509894T3 (en) 2008-05-19 2014-10-20 Idexx Laboratories Inc Methods, devices, kits and compositions for detecting roundworm, whip worm and hookworm
CA2780807C (en) 2009-11-17 2020-01-21 Idexx Laboratories, Inc. Methods, devices, kits and compositions for detecting roundworm

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
BIN ET AL.: "Ancylostoma secreted protein 1 (ASP-1) homologues in human hookworms", MOLECULAR AND BIOCHEMICAL PARASITOLOGY, vol. 98, 1999, pages 143 - 149, XP002964543 *
HOTEZ ET AL.: "Experimental approaches to the development of a recombinant hookworm vaccine", IMMUNOLOGICAL REVIEWS, vol. 171, 1999, pages 163 - 172, XP001000926 *
SEN ET AL.: "Hookworm burden reductions in BALB/c mice vaccinated with recombinant ancylostoma secreted proteins (ASPs) from ancylostoma duodenale, ancylostoma caninum and necator americanus", VACCINE, vol. 18, 2000, pages 1096 - 1102, XP001005230 *

Also Published As

Publication number Publication date
AU2002335061A1 (en) 2003-04-28
WO2003032917A2 (en) 2003-04-24
CN1571677A (en) 2005-01-26
BR0213656A (en) 2006-05-23

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