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WO2003025150A3 - Lipid-associated molecules - Google Patents

Lipid-associated molecules Download PDF

Info

Publication number
WO2003025150A3
WO2003025150A3 PCT/US2002/029980 US0229980W WO03025150A3 WO 2003025150 A3 WO2003025150 A3 WO 2003025150A3 US 0229980 W US0229980 W US 0229980W WO 03025150 A3 WO03025150 A3 WO 03025150A3
Authority
WO
WIPO (PCT)
Prior art keywords
lipam
lipid
associated molecules
associatedmolecules
polynucleotides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2002/029980
Other languages
French (fr)
Other versions
WO2003025150A2 (en
Inventor
Bridget A Warren
Brooke M Emerling
Ernestine A Lee
Hsin-Ru Chang
Ian J Forsythe
Jennifer A Griffin
Mariah R Baughn
Narinder K Chawla
Reena Khare
Roopa Reddy
Sally Lee
Sean A Bulloch
Soo Yeun Lee
Uyen K Tran
Vicki S Elliott
Y Tom Tang
Umesh Bhatia
John D Burrill
Julie J Blake
Anne Ho
Wenjin Zheng
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Incyte Genomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc filed Critical Incyte Genomics Inc
Priority to CA002460812A priority Critical patent/CA2460812A1/en
Priority to JP2003529924A priority patent/JP2005514007A/en
Priority to EP02799014A priority patent/EP1461446A2/en
Priority to AU2002334632A priority patent/AU2002334632A1/en
Publication of WO2003025150A2 publication Critical patent/WO2003025150A2/en
Anticipated expiration legal-status Critical
Publication of WO2003025150A3 publication Critical patent/WO2003025150A3/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Various embodiments of the invention provide human lipid-associatedmolecules (LIPAM) and polynucleotides which identify and encode LIPAM. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of LIPAM.
PCT/US2002/029980 2001-09-21 2002-09-19 Lipid-associated molecules Ceased WO2003025150A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002460812A CA2460812A1 (en) 2001-09-21 2002-09-19 Lipid-associated molecules
JP2003529924A JP2005514007A (en) 2001-09-21 2002-09-19 Lipid related molecules
EP02799014A EP1461446A2 (en) 2001-09-21 2002-09-19 Lipid-associated molecules
AU2002334632A AU2002334632A1 (en) 2001-09-21 2002-09-19 Lipid-associated molecules

Applications Claiming Priority (16)

Application Number Priority Date Filing Date Title
US32403901P 2001-09-21 2001-09-21
US60/324,039 2001-09-21
US34619701P 2001-10-26 2001-10-26
US60/346,197 2001-10-26
US34387601P 2001-11-02 2001-11-02
US60/343,876 2001-11-02
US33421101P 2001-11-30 2001-11-30
US60/334,211 2001-11-30
US34022301P 2001-12-14 2001-12-14
US60/340,223 2001-12-14
US34216601P 2001-12-18 2001-12-18
US60/342,166 2001-12-18
US35126202P 2002-01-22 2002-01-22
US60/351,262 2002-01-22
US37757602P 2002-05-03 2002-05-03
US60/377,576 2002-05-03

Publications (2)

Publication Number Publication Date
WO2003025150A2 WO2003025150A2 (en) 2003-03-27
WO2003025150A3 true WO2003025150A3 (en) 2004-07-29

Family

ID=27575387

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/029980 Ceased WO2003025150A2 (en) 2001-09-21 2002-09-19 Lipid-associated molecules

Country Status (5)

Country Link
EP (1) EP1461446A2 (en)
JP (1) JP2005514007A (en)
AU (1) AU2002334632A1 (en)
CA (1) CA2460812A1 (en)
WO (1) WO2003025150A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7972802B2 (en) 2005-10-31 2011-07-05 University Of Washington Lipoprotein-associated markers for cardiovascular disease
US8241861B1 (en) 2008-07-08 2012-08-14 Insilicos, Llc Methods and compositions for diagnosis or prognosis of cardiovascular disease
CA2991862A1 (en) * 2015-07-31 2017-02-09 Vascular Biogenics Ltd. Motile sperm domain containing protein 2 and inflammation
NZ738875A (en) * 2015-07-31 2023-06-30 Vascular Biogenics Ltd Motile sperm domain containing protein 2 and cancer

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE GENBANK [online] XP002979899, Database accession no. (AAA36628) *

Also Published As

Publication number Publication date
WO2003025150A2 (en) 2003-03-27
CA2460812A1 (en) 2003-03-27
JP2005514007A (en) 2005-05-19
EP1461446A2 (en) 2004-09-29
AU2002334632A1 (en) 2003-04-01

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