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WO2003009783A1 - Lamines pour traitement de la cornee et leur procede de production - Google Patents

Lamines pour traitement de la cornee et leur procede de production Download PDF

Info

Publication number
WO2003009783A1
WO2003009783A1 PCT/JP2002/007491 JP0207491W WO03009783A1 WO 2003009783 A1 WO2003009783 A1 WO 2003009783A1 JP 0207491 W JP0207491 W JP 0207491W WO 03009783 A1 WO03009783 A1 WO 03009783A1
Authority
WO
WIPO (PCT)
Prior art keywords
cornea
laminates
face
contact
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2002/007491
Other languages
English (en)
Japanese (ja)
Inventor
Minoru Ueda
Ken-Ichiro Hata
Koji Hirano
Kazuhiro Kito
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Japan Tissue Engineering Co Ltd
Original Assignee
Japan Tissue Engineering Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Tissue Engineering Co Ltd filed Critical Japan Tissue Engineering Co Ltd
Priority to JP2003515179A priority Critical patent/JPWO2003009783A1/ja
Priority to KR10-2003-7016445A priority patent/KR20040024859A/ko
Publication of WO2003009783A1 publication Critical patent/WO2003009783A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3813—Epithelial cells, e.g. keratinocytes, urothelial cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/16—Materials or treatment for tissue regeneration for reconstruction of eye parts, e.g. intraocular lens, cornea

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Botany (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Urology & Nephrology (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

L'invention concerne des laminés destinés au traitement de la cornée qui sont efficaces et extrêmement pratiques à utiliser, facilitant ainsi le traitement de la cornée. Ces laminés sont composés d'un matériau de base présentant une face incurvée, ce qui permet sa mise en place sur la cornée, et une couche cellulaire posée directement ou indirectement au moins sur la face du matériau de base à mettre en contact avec la cornée et/ou celle à ne pas mettre en contact avec la cornée. Ces laminés, qui ont une couche cellulaire sur la face à mettre en contact avec la cornée, sont préparés par inoculation de cellules épithéliales de la muqueuse buccale à l'intérieur d'une lentille en collagène, par culture des cellules pendant 14 jours, ce qui permet de former une couche cellulaire composée des cellules épithéliales de la muqueuse buccale sur la face à mettre en contact avec la cornée.
PCT/JP2002/007491 2001-07-25 2002-07-24 Lamines pour traitement de la cornee et leur procede de production Ceased WO2003009783A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2003515179A JPWO2003009783A1 (ja) 2001-07-25 2002-07-24 角膜治療用積層体及びその製造方法
KR10-2003-7016445A KR20040024859A (ko) 2001-07-25 2002-07-24 각막 치료용 적층체 및 그 제조방법

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001224699 2001-07-25
JP2001-224699 2001-07-25

Publications (1)

Publication Number Publication Date
WO2003009783A1 true WO2003009783A1 (fr) 2003-02-06

Family

ID=19057815

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2002/007491 Ceased WO2003009783A1 (fr) 2001-07-25 2002-07-24 Lamines pour traitement de la cornee et leur procede de production

Country Status (3)

Country Link
JP (1) JPWO2003009783A1 (fr)
KR (1) KR20040024859A (fr)
WO (1) WO2003009783A1 (fr)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006003818A1 (fr) * 2004-06-30 2006-01-12 Alblast Co., Ltd. Surface épithéliale cornéenne et processus de production
JPWO2005047496A1 (ja) * 2003-11-14 2007-05-31 学校法人慶應義塾 細胞培養法、細胞の三次元培養法、三次元組織、人工臓器、及び組織移植方法
CN100333702C (zh) * 2004-04-28 2007-08-29 浙江大学医学院附属邵逸夫医院 一种无细胞的异种角膜基质及制备方法和用途
WO2008105454A1 (fr) 2007-02-28 2008-09-04 Senju Pharmaceutical Co., Ltd. Cellule pouvant exprimer une grande quantité de lacritine
EP2417933A3 (fr) * 2010-08-11 2012-08-22 Body Organ Biomedical Corp. Feuille biologique pour réparation de tissu oculaire
US10457913B2 (en) 2015-01-13 2019-10-29 Osaka University Corneal epithelioid cells derived from surface ectodermal cells
JP2021518136A (ja) * 2018-03-22 2021-08-02 クイーン メアリー ユニバーシティ オブ ロンドン 疾患を治療するためのインプラント型セルドレッシング

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021152083A2 (fr) 2020-01-31 2021-08-05 Schott Ag Article de type carreau et son utilisation, et appareil électroménager comportant ce dernier

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5192316A (en) * 1988-02-16 1993-03-09 Allergan, Inc. Ocular device
US5374515A (en) * 1992-11-13 1994-12-20 Organogenesis, Inc. In vitro cornea equivalent model
US5827641A (en) * 1992-11-13 1998-10-27 Parenteau; Nancy L. In vitro cornea equivalent model
US5836313A (en) * 1993-02-08 1998-11-17 Massachusetts Institute Of Technology Methods for making composite hydrogels for corneal prostheses

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5192316A (en) * 1988-02-16 1993-03-09 Allergan, Inc. Ocular device
US5374515A (en) * 1992-11-13 1994-12-20 Organogenesis, Inc. In vitro cornea equivalent model
US5827641A (en) * 1992-11-13 1998-10-27 Parenteau; Nancy L. In vitro cornea equivalent model
US5836313A (en) * 1993-02-08 1998-11-17 Massachusetts Institute Of Technology Methods for making composite hydrogels for corneal prostheses

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2005047496A1 (ja) * 2003-11-14 2007-05-31 学校法人慶應義塾 細胞培養法、細胞の三次元培養法、三次元組織、人工臓器、及び組織移植方法
CN100333702C (zh) * 2004-04-28 2007-08-29 浙江大学医学院附属邵逸夫医院 一种无细胞的异种角膜基质及制备方法和用途
WO2006003818A1 (fr) * 2004-06-30 2006-01-12 Alblast Co., Ltd. Surface épithéliale cornéenne et processus de production
WO2008105454A1 (fr) 2007-02-28 2008-09-04 Senju Pharmaceutical Co., Ltd. Cellule pouvant exprimer une grande quantité de lacritine
EP2417933A3 (fr) * 2010-08-11 2012-08-22 Body Organ Biomedical Corp. Feuille biologique pour réparation de tissu oculaire
US10457913B2 (en) 2015-01-13 2019-10-29 Osaka University Corneal epithelioid cells derived from surface ectodermal cells
JP2021518136A (ja) * 2018-03-22 2021-08-02 クイーン メアリー ユニバーシティ オブ ロンドン 疾患を治療するためのインプラント型セルドレッシング
JP7519298B2 (ja) 2018-03-22 2024-07-19 クイーン メアリー ユニバーシティ オブ ロンドン 疾患を治療するためのインプラント型セルドレッシング
JP2024129142A (ja) * 2018-03-22 2024-09-26 クイーン メアリー ユニバーシティ オブ ロンドン 疾患を治療するためのインプラント型セルドレッシング
US12171911B2 (en) 2018-03-22 2024-12-24 Queen Mary University Of London Implantable cell dressing for treatment of disease

Also Published As

Publication number Publication date
JPWO2003009783A1 (ja) 2004-11-11
KR20040024859A (ko) 2004-03-22

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