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WO2003004531A3 - Regulation of human somatostatin receptor-like protein - Google Patents

Regulation of human somatostatin receptor-like protein Download PDF

Info

Publication number
WO2003004531A3
WO2003004531A3 PCT/EP2002/007564 EP0207564W WO03004531A3 WO 2003004531 A3 WO2003004531 A3 WO 2003004531A3 EP 0207564 W EP0207564 W EP 0207564W WO 03004531 A3 WO03004531 A3 WO 03004531A3
Authority
WO
WIPO (PCT)
Prior art keywords
protein
somatostatin receptor
human somatostatin
regulation
reagents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2002/007564
Other languages
French (fr)
Other versions
WO2003004531A2 (en
Inventor
Shyam Ramakrishnan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer Healthcare AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare AG filed Critical Bayer Healthcare AG
Publication of WO2003004531A2 publication Critical patent/WO2003004531A2/en
Publication of WO2003004531A3 publication Critical patent/WO2003004531A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575—Hormones
    • G01N2333/655—Somatostatins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Reagents which regulate human somatostatin receptor-like protein and reagents which bind to human somatostatin receptor-like gene products can be used to regulate the effect of somatostatin. Peripheral and central nervous system diseases, cardiovascular diseases, hematological diseases, obesity, diabetes, asthma and cancers can be treated.
PCT/EP2002/007564 2001-07-06 2002-07-08 Regulation of human somatostatin receptor-like protein Ceased WO2003004531A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP2001/007737 WO2003004530A1 (en) 2001-07-06 2001-07-06 Regulation of human somatostatin receptor-like protein
EPPCT/EP01/07737 2001-07-06

Publications (2)

Publication Number Publication Date
WO2003004531A2 WO2003004531A2 (en) 2003-01-16
WO2003004531A3 true WO2003004531A3 (en) 2003-12-04

Family

ID=8164490

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/EP2001/007737 Ceased WO2003004530A1 (en) 2001-07-06 2001-07-06 Regulation of human somatostatin receptor-like protein
PCT/EP2002/007564 Ceased WO2003004531A2 (en) 2001-07-06 2002-07-08 Regulation of human somatostatin receptor-like protein

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/007737 Ceased WO2003004530A1 (en) 2001-07-06 2001-07-06 Regulation of human somatostatin receptor-like protein

Country Status (1)

Country Link
WO (2) WO2003004530A1 (en)

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999037679A1 (en) * 1998-01-26 1999-07-29 Millennium Pharmaceuticals, Inc. Ligand receptors and uses therefor
WO2000064942A1 (en) * 1999-04-27 2000-11-02 Smithkline Beecham Corporation Axor-27, a g-protein coupled receptor
WO2001012673A1 (en) * 1999-08-17 2001-02-22 Merck Patent Gmbh Pgpcr-3 polypeptides and dna sequences thereof
WO2001036471A2 (en) * 1999-11-17 2001-05-25 Arena Pharmaceuticals, Inc. Endogenous and non-endogenous versions of human g protein-coupled receptors
WO2001036473A2 (en) * 1999-11-16 2001-05-25 Pharmacia & Upjohn Company Human g protein-coupled receptors
WO2001042288A2 (en) * 1999-12-10 2001-06-14 Incyte Genomics, Inc. G-protein coupled receptors
WO2001048188A1 (en) * 1999-12-28 2001-07-05 Helix Research Institute Novel guanosine triphosphate-binding protein-coupled receptors, genes thereof and production and use of the same
WO2001068848A2 (en) * 2000-03-01 2001-09-20 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
WO2001090189A2 (en) * 2000-05-24 2001-11-29 Akzo Nobel N.V. G-protein coupled receptor org3.

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999037679A1 (en) * 1998-01-26 1999-07-29 Millennium Pharmaceuticals, Inc. Ligand receptors and uses therefor
WO2000064942A1 (en) * 1999-04-27 2000-11-02 Smithkline Beecham Corporation Axor-27, a g-protein coupled receptor
WO2001012673A1 (en) * 1999-08-17 2001-02-22 Merck Patent Gmbh Pgpcr-3 polypeptides and dna sequences thereof
WO2001036473A2 (en) * 1999-11-16 2001-05-25 Pharmacia & Upjohn Company Human g protein-coupled receptors
WO2001036471A2 (en) * 1999-11-17 2001-05-25 Arena Pharmaceuticals, Inc. Endogenous and non-endogenous versions of human g protein-coupled receptors
WO2001042288A2 (en) * 1999-12-10 2001-06-14 Incyte Genomics, Inc. G-protein coupled receptors
WO2001048188A1 (en) * 1999-12-28 2001-07-05 Helix Research Institute Novel guanosine triphosphate-binding protein-coupled receptors, genes thereof and production and use of the same
WO2001068848A2 (en) * 2000-03-01 2001-09-20 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
WO2001090189A2 (en) * 2000-05-24 2001-11-29 Akzo Nobel N.V. G-protein coupled receptor org3.

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Section Ch Week 200145, Derwent World Patents Index; Class B04, AN 2001-425662, XP002190613 *
LEE D K ET AL: "Discovery and mapping of ten novel G protein-coupled receptor genes", GENE: AN INTERNATIONAL JOURNAL ON GENES AND GENOMES, ELSEVIER SCIENCE PUBLISHERS, BARKING, GB, vol. 275, no. 1, 5 September 2001 (2001-09-05), pages 83 - 91, XP004307114, ISSN: 0378-1119 *

Also Published As

Publication number Publication date
WO2003004531A2 (en) 2003-01-16
WO2003004530A1 (en) 2003-01-16

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