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WO2003097008A3 - Transdermal delivery device for the administration of fentanyl - Google Patents

Transdermal delivery device for the administration of fentanyl Download PDF

Info

Publication number
WO2003097008A3
WO2003097008A3 PCT/GB2003/002120 GB0302120W WO03097008A3 WO 2003097008 A3 WO2003097008 A3 WO 2003097008A3 GB 0302120 W GB0302120 W GB 0302120W WO 03097008 A3 WO03097008 A3 WO 03097008A3
Authority
WO
WIPO (PCT)
Prior art keywords
fentanyl
administration
delivery device
transdermal delivery
irritant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB2003/002120
Other languages
French (fr)
Other versions
WO2003097008A2 (en
Inventor
Francisco Jose Evarist Stefano
Alejandro Fabio Scasso
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
THALAS GROUP Inc
PAGET HUGH CHARLES EDWARD
Original Assignee
THALAS GROUP Inc
PAGET HUGH CHARLES EDWARD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ARP020101791A external-priority patent/AR033748A1/en
Priority claimed from GB0229836A external-priority patent/GB0229836D0/en
Application filed by THALAS GROUP Inc, PAGET HUGH CHARLES EDWARD filed Critical THALAS GROUP Inc
Priority to AU2003230034A priority Critical patent/AU2003230034A1/en
Publication of WO2003097008A2 publication Critical patent/WO2003097008A2/en
Publication of WO2003097008A3 publication Critical patent/WO2003097008A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061Polyacrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4468Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A simple, non-irritant and chemically stable transdermal delivery device for the administration of fentanyl comprises a pressure sensitive acrylic adhesive matrix formed by a non-functional copolymer containing 2-5 % by weight of fentanyl, and lauryl alcohol as a permeation enhancer.
PCT/GB2003/002120 2002-05-15 2003-05-15 Transdermal delivery device for the administration of fentanyl Ceased WO2003097008A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003230034A AU2003230034A1 (en) 2002-05-15 2003-05-15 Transdermal delivery device for the administration of fentanyl

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AR020101791 2002-05-15
ARP020101791A AR033748A1 (en) 2002-05-15 2002-05-15 A DEVICE FOR THE TRANSDERMAL ADMINISTRATION OF PHARMACOLOGICALLY ACTIVE SUBSTANCES THAT INCLUDES TWO SUPERPOSED ADHESIVE LAYERS AND A PROCEDURE TO PREPARE IT
GB0229836A GB0229836D0 (en) 2002-12-20 2002-12-20 Transdermal delivery device for the administration of fentanyl
GB0229836.2 2002-12-20

Publications (2)

Publication Number Publication Date
WO2003097008A2 WO2003097008A2 (en) 2003-11-27
WO2003097008A3 true WO2003097008A3 (en) 2004-03-18

Family

ID=29550643

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2003/002120 Ceased WO2003097008A2 (en) 2002-05-15 2003-05-15 Transdermal delivery device for the administration of fentanyl

Country Status (2)

Country Link
AU (1) AU2003230034A1 (en)
WO (1) WO2003097008A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180263920A1 (en) * 2014-12-19 2018-09-20 3M Innovative Properties Company Transdermal drug delivery device including fentanyl
WO2022107182A1 (en) * 2020-11-18 2022-05-27 University Of Petra A composition of fentanyl and fatty acids, and a method of preparation thereof
CN112656778A (en) * 2020-12-28 2021-04-16 广东红珊瑚药业有限公司 Pressure-sensitive adhesive matrix and patch

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0842662A1 (en) * 1996-05-13 1998-05-20 Hisamitsu Pharmaceutical Co., Inc. Percutaneous tape preparation containing fentanyl
WO2001026705A2 (en) * 1999-10-11 2001-04-19 Samyang Corporation A dual adhesive transdermal drug delivery system

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0842662A1 (en) * 1996-05-13 1998-05-20 Hisamitsu Pharmaceutical Co., Inc. Percutaneous tape preparation containing fentanyl
WO2001026705A2 (en) * 1999-10-11 2001-04-19 Samyang Corporation A dual adhesive transdermal drug delivery system

Also Published As

Publication number Publication date
WO2003097008A2 (en) 2003-11-27
AU2003230034A1 (en) 2003-12-02
AU2003230034A8 (en) 2003-12-02

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