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WO2003094731A1 - Procede de prelevement sanguin indolore - Google Patents

Procede de prelevement sanguin indolore Download PDF

Info

Publication number
WO2003094731A1
WO2003094731A1 PCT/JP2003/005578 JP0305578W WO03094731A1 WO 2003094731 A1 WO2003094731 A1 WO 2003094731A1 JP 0305578 W JP0305578 W JP 0305578W WO 03094731 A1 WO03094731 A1 WO 03094731A1
Authority
WO
WIPO (PCT)
Prior art keywords
puncture
skin
finger
joint
puncturing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2003/005578
Other languages
English (en)
Japanese (ja)
Inventor
Toru Nakayama
Mariko Nakayama
Masafumi Nakayama
Takayuki Nakayama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2002167855A external-priority patent/JP2003319925A/ja
Application filed by Individual filed Critical Individual
Priority to AU2003235830A priority Critical patent/AU2003235830A1/en
Publication of WO2003094731A1 publication Critical patent/WO2003094731A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/150022—Source of blood for capillary blood or interstitial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150053—Details for enhanced collection of blood or interstitial fluid at the sample site, e.g. by applying compression, heat, vibration, ultrasound, suction or vacuum to tissue; for reduction of pain or discomfort; Skin piercing elements, e.g. blades, needles, lancets or canulas, with adjustable piercing speed
    • A61B5/150106—Means for reducing pain or discomfort applied before puncturing; desensitising the skin at the location where body is to be pierced

Definitions

  • the present invention relates to a method for puncturing the skin with a puncture needle and bleeding the skin to reduce the pain associated with puncture. It is useful for measuring autoglycemia in patients with urine disease. It is suitable for testing that requires a small amount of blood sample. Disgusting background
  • skin puncture is performed at a depth of from 0.1 awake to 0.5 mm or less including an error so as to awaken the skin puncture force.
  • the thickness of the epidermis of the skin is 0.07 to 0.12 mm.
  • the epidermis of the palms and soles is even thicker, with the palm epidermis as thick as 0.8 mm and the sole epidermis as thick as 1.4 mm.
  • Below the epidermis is the dermis.
  • blood vessels such as the lower vascular network around the season. The nerve endings that control pain are distributed between the epidermis and the dermis.
  • the puncture depth is set to the minimum depth at which the puncture needle penetrates the epidermis and damages the vascular network just below the epidermis. If the puncture is shallow, the puncture will cause less damage to the skin fibers.
  • hand Fingers, forearms, abdomen and earlobes are easy to puncture.
  • fingertip age is recommended on the palm side or side of the fingertip. Puncturing the dorsal side of the finger is not recommended.
  • Figure 1 shows the puncture sound! ⁇ On the back of the finger.
  • the description of the reference numerals in the drawings is described below.
  • the puncture depth of a currently available self-fixating puncture device is 0.4 mm or more. Also, the puncture depth varies widely, ranging from ⁇ 0.2 to 0.3 ⁇ . In order to control the depth of puncture and perform painless puncture with good reversibility, the depth of puncture and the variation in the puncture of the commercially available puncture I intestine are too large.
  • the skin puncture at the depth of the thigh was performed with an accuracy of ( ⁇ 0.075 mm).
  • the depth of the puncture was shallower and the pain at the time of puncture was less.
  • skin puncture including errors, at a depth of at least 0.1 awake and under 0.5 mm.
  • the puncture force of the puncture device or puncture needle with a puncture error of ⁇ 0.2 mm is required to be punctured at 0.3 mm.
  • the body parts that can puncture the skin with the above-mentioned depth without pain and with slight pain are considered to be multiple, but the places that can be easily punctured are the shooting point, forearm, abdomen and earlobe.
  • the depth of the puncture was shallow, so bleeding was not recognized only by puncturing the skin.
  • compression around the puncture site or suction by negative pressure at the puncture site is necessary to obtain a blood sample: ⁇ .
  • the fingertip In finger puncture, the fingertip is often used for puncture. However, since the painful area is located on the palm side of the fingertip, the side and side of the fingertip are appropriate parts for puncture.
  • the back of the fingertip is not listed as a puncture site in the patient manual attached to self-sickle measurement. This time we found a site suitable for »
  • the puncture in the skin on the back side of the skin is the finger joint (IP joint of the thumb, DIP joint of the 2nd to 5th fingers), the part to the posterior nail fold, and the «tree from the nail fold to the side / ⁇ Department.
  • the puncture site is shown in (2) of the drawing. The area near the hairline of the nail causes abundant blood flow, causing bleeding.
  • the posterior nail fold and the tree part from the posterior nail fold to the lateral nail fold are the # 1 puncture site. This is shown in (2a) in the figure. Because the puncture is too shallow even in # 11, it is often not possible to obtain the required amount of blood only by puncturing the skin, such as the finger joint of the punctured finger (IP joint of the thumb, second to fifth Flexion of the DIP joint of the finger), puncture by pressing the central part of the finger rather than the puncture sound ⁇ , or puncturing the finger's palmar side of the pierced finger If the required amount of blood cannot be obtained by the above operation, the punctured finger should be stretched and then repeat the above operation.This 1 ⁇ 2fe does not require suction of ⁇ 3 ⁇ 4fc fluid by negative pressure. Industrial available
  • the painless method of the present invention not only reduces the pain of the patient, but also has medical economics advantages.
  • the present method requires expensive equipment, such as a blood squeezing pump, especially on the side and the side of ⁇ t, and can perform tmfc.
  • a blood squeezing pump especially on the side and the side of ⁇ t, and can perform tmfc.
  • a conventional blood glucose measuring device that is already widely used can be used as it is. Because of this many diabetes The patient can use the painless blood glucose measurement system.
  • the method can also be applied to other tests that can be performed on small blood samples in addition to self-blood glucose measurement.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

L'invention concerne un procédé permettant de prélever une petite quantité de sang de manière indolore ou quasi-indolore par perforation de la peau au moyen d'une aiguille. La douleur entraînée par cette perforation peut être éliminée ou atténuée si l'aiguille est introduite de manière adéquate, à une profondeur comprise entre 0,1 et 0,5 mm. Ce procédé peut être utilisé pour différentes parties du corps, y compris les doigts, les avant-bras, l'abdomen et les lobes auriculaires. Parmi les nouveaux sites de perforation développés, figurent une zone située à l'arrière des doigts, entre une articulation (l'articulation interphalangienne (IP) du pouce ou l'articulation interphalangienne distale (DIP) de l'index, du majeur, de l'annulaire ou de l'auriculaire) et le sillon arrière de l'ongle, ainsi qu'une zone comprise entre le sillon arrière de l'ongle et le sillon latéral de l'ongle. Le procédé de prélèvement sanguin selon l'invention permet principalement à un patient diabétique de mesurer de manière autonome son taux de glycémie. En outre, ce procédé peut être utilisé pour d'autres examens effectués au moyen d'un petit échantillon sanguin.
PCT/JP2003/005578 2002-05-07 2003-05-01 Procede de prelevement sanguin indolore Ceased WO2003094731A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003235830A AU2003235830A1 (en) 2002-05-07 2003-05-01 Painless blood collection method

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2002-167855 2002-05-07
JP2002167855A JP2003319925A (ja) 2002-05-07 2002-05-07 無痛皮膚穿刺による採血法
JP2003-74592 2003-02-13
JP2003074592 2003-02-13

Publications (1)

Publication Number Publication Date
WO2003094731A1 true WO2003094731A1 (fr) 2003-11-20

Family

ID=29422479

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2003/005578 Ceased WO2003094731A1 (fr) 2002-05-07 2003-05-01 Procede de prelevement sanguin indolore

Country Status (2)

Country Link
AU (1) AU2003235830A1 (fr)
WO (1) WO2003094731A1 (fr)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07275223A (ja) * 1992-04-13 1995-10-24 Boehringer Mannheim Gmbh 採血用血液ランセット装置
JPH11253409A (ja) * 1998-03-11 1999-09-21 Nec Corp 角質層穿刺針及び角質層穿刺部材
JP2000116768A (ja) * 1998-10-19 2000-04-25 Terumo Corp 穿刺器具
JP2001524343A (ja) * 1997-12-02 2001-12-04 アボット・ラボラトリーズ 診断テスト用間質液を得るための方法及び装置

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07275223A (ja) * 1992-04-13 1995-10-24 Boehringer Mannheim Gmbh 採血用血液ランセット装置
JP2001524343A (ja) * 1997-12-02 2001-12-04 アボット・ラボラトリーズ 診断テスト用間質液を得るための方法及び装置
JPH11253409A (ja) * 1998-03-11 1999-09-21 Nec Corp 角質層穿刺針及び角質層穿刺部材
JP2000116768A (ja) * 1998-10-19 2000-04-25 Terumo Corp 穿刺器具

Also Published As

Publication number Publication date
AU2003235830A1 (en) 2003-11-11

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