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WO2003093247A3 - Nouveaux agents antibacteriens - Google Patents

Nouveaux agents antibacteriens Download PDF

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Publication number
WO2003093247A3
WO2003093247A3 PCT/IB2003/001571 IB0301571W WO03093247A3 WO 2003093247 A3 WO2003093247 A3 WO 2003093247A3 IB 0301571 W IB0301571 W IB 0301571W WO 03093247 A3 WO03093247 A3 WO 03093247A3
Authority
WO
WIPO (PCT)
Prior art keywords
antibacterial agents
derivatives
pharmaceutically acceptable
present
provides novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2003/001571
Other languages
English (en)
Other versions
WO2003093247A2 (fr
Inventor
Shiv Kumar Agarwal
Surendrakumar Satyanara Pandey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orchid Pharma Ltd
Original Assignee
Orchid Chemicals and Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orchid Chemicals and Pharmaceuticals Ltd filed Critical Orchid Chemicals and Pharmaceuticals Ltd
Priority to AU2003224345A priority Critical patent/AU2003224345A1/en
Publication of WO2003093247A2 publication Critical patent/WO2003093247A2/fr
Publication of WO2003093247A3 publication Critical patent/WO2003093247A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne de nouveaux dérivés de l'oxazolidinone de la formule (1), leurs dérivés, leurs analogues, leurs formes tautomères, leurs stéréoisomères, leurs polymorphes, leurs hydrates, leurs solvates, leurs sels pharmaceutiquement acceptables et des compositions pharmaceutiquement acceptables les contenant. L'invention se rapporte en particulier à de nouveaux dérivés de l'oxazolidinone de la formule générale (1).
PCT/IB2003/001571 2002-04-30 2003-04-25 Nouveaux agents antibacteriens Ceased WO2003093247A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003224345A AU2003224345A1 (en) 2002-04-30 2003-04-25 Antibacterial agents

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN329/MAS/2002 2002-04-30
IN329CH2002 2002-04-30

Publications (2)

Publication Number Publication Date
WO2003093247A2 WO2003093247A2 (fr) 2003-11-13
WO2003093247A3 true WO2003093247A3 (fr) 2003-12-24

Family

ID=29287797

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2003/001571 Ceased WO2003093247A2 (fr) 2002-04-30 2003-04-25 Nouveaux agents antibacteriens

Country Status (2)

Country Link
AU (1) AU2003224345A1 (fr)
WO (1) WO2003093247A2 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003253141A1 (en) * 2002-08-22 2004-03-11 Orchid Chemicals And Pharmaceuticals Ltd Novel antibacterial agents
CA2602073A1 (fr) * 2005-02-24 2006-08-31 Teva Pharmaceutical Industries Ltd. Procedes de preparation d'intermediaire linezolid
JP2008544979A (ja) 2005-06-29 2008-12-11 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー 抗菌剤としてのホモモルホリンオキサゾリジノン
WO2008090570A1 (fr) * 2007-01-25 2008-07-31 Panacea Biotec Ltd Nouveaux antimicrobiens
CL2008001003A1 (es) * 2007-04-11 2008-10-17 Actelion Pharmaceuticals Ltd Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana.
CN108348507B (zh) * 2015-07-17 2021-10-08 结核病药物开发全球联盟公司 用于抗微生物治疗的经取代苯基噁唑烷酮
WO2017156519A1 (fr) * 2016-03-11 2017-09-14 The Board Of Trustees Of The University Of Illinois Petites molécules actives contre les bactéries à gram négatif
WO2018237140A1 (fr) 2017-06-23 2018-12-27 The Board Of Trustees Of The University Of Illinois Inhibiteurs de la topoisomérase ayant une activité antibactérienne et une activité anti-cancéreuse
CN107382893B (zh) * 2017-07-18 2020-04-28 郑州大学 具有抗菌活性的利奈唑胺碱阳离子两亲性化合物及其制备方法
WO2021184339A1 (fr) 2020-03-20 2021-09-23 Merck Sharp & Dohme Corp. Composé d'oxazolidinone et procédés d'utilisation de celui-ci comme agent antibactérien

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995007271A1 (fr) * 1993-09-09 1995-03-16 The Upjohn Company Agents antimicrobiens oxazolidinone a substitution oxazine et thiazine
US5688792A (en) * 1994-08-16 1997-11-18 Pharmacia & Upjohn Company Substituted oxazine and thiazine oxazolidinone antimicrobials
WO1998001446A1 (fr) * 1996-07-06 1998-01-15 Zeneca Limited Derives substitues de piperazinyle-phenyle-oxazolidinone et leur utilisation en tant qu'agents antibacteriens
WO2001042242A1 (fr) * 1999-08-12 2001-06-14 Ortho-Mcneil Pharmaceutical, Inc. Phenyl-oxazolidinones substitutees heterobicycliques antibacteriennes
WO2001098297A2 (fr) * 2000-06-16 2001-12-27 Pharmacia & Up John Company Thiazine oxazolidinone
WO2002002095A2 (fr) * 2000-06-30 2002-01-10 Pharmacia & Upjohn Company Composition et techniques de traitement d'infections bacteriennes
WO2002006278A1 (fr) * 2000-07-17 2002-01-24 Ranbaxy Laboratories Limited Derives d'oxazolidinone utilises en tant qu'antimicrobiens
WO2002064574A2 (fr) * 2001-02-07 2002-08-22 Ortho-Mcneil Pharmaceutical, Inc. Antibactériens à base de pyridoarylphényle oxazolidinone, compositions et procédés associés

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995007271A1 (fr) * 1993-09-09 1995-03-16 The Upjohn Company Agents antimicrobiens oxazolidinone a substitution oxazine et thiazine
US5688792A (en) * 1994-08-16 1997-11-18 Pharmacia & Upjohn Company Substituted oxazine and thiazine oxazolidinone antimicrobials
WO1998001446A1 (fr) * 1996-07-06 1998-01-15 Zeneca Limited Derives substitues de piperazinyle-phenyle-oxazolidinone et leur utilisation en tant qu'agents antibacteriens
WO2001042242A1 (fr) * 1999-08-12 2001-06-14 Ortho-Mcneil Pharmaceutical, Inc. Phenyl-oxazolidinones substitutees heterobicycliques antibacteriennes
WO2001098297A2 (fr) * 2000-06-16 2001-12-27 Pharmacia & Up John Company Thiazine oxazolidinone
WO2002002095A2 (fr) * 2000-06-30 2002-01-10 Pharmacia & Upjohn Company Composition et techniques de traitement d'infections bacteriennes
WO2002006278A1 (fr) * 2000-07-17 2002-01-24 Ranbaxy Laboratories Limited Derives d'oxazolidinone utilises en tant qu'antimicrobiens
WO2002064574A2 (fr) * 2001-02-07 2002-08-22 Ortho-Mcneil Pharmaceutical, Inc. Antibactériens à base de pyridoarylphényle oxazolidinone, compositions et procédés associés

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PAE A N ET AL: "Synthesis and in vitro activity of new oxazolidinone antibacterial agents having substituted isoxazoles", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, OXFORD, GB, vol. 9, no. 18, 20 September 1999 (1999-09-20), pages 2679 - 2684, XP004179951, ISSN: 0960-894X *

Also Published As

Publication number Publication date
AU2003224345A8 (en) 2003-11-17
WO2003093247A2 (fr) 2003-11-13
AU2003224345A1 (en) 2003-11-17

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