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WO2003091419A3 - Kinases and phosphatases - Google Patents

Kinases and phosphatases Download PDF

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Publication number
WO2003091419A3
WO2003091419A3 PCT/US2003/013124 US0313124W WO03091419A3 WO 2003091419 A3 WO2003091419 A3 WO 2003091419A3 US 0313124 W US0313124 W US 0313124W WO 03091419 A3 WO03091419 A3 WO 03091419A3
Authority
WO
WIPO (PCT)
Prior art keywords
kpp
phosphatases
kinases
polynucleotides
agonists
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2003/013124
Other languages
French (fr)
Other versions
WO2003091419A2 (en
Inventor
Patricia M Mason
Hsin-Ru Chang
Laura Y Kamigaki
Anne L Curtis
Vicki S Elliott
Reena Khare
Thomas W Richardson
Amy E Kable
Anita Swarnakar
Joseph P Marquis
Jayalaxmi Ramkumar
April J A Hafalia
Uyen K Tran
Amy D Wilson
Pei Jin
Erika A Lindquist
Xin Jiang
Alan A Jackson
Kimberly J Gietzen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Incyte Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Corp filed Critical Incyte Corp
Priority to AU2003231531A priority Critical patent/AU2003231531A1/en
Publication of WO2003091419A2 publication Critical patent/WO2003091419A2/en
Publication of WO2003091419A3 publication Critical patent/WO2003091419A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Various embodiments of the invention provide human kinases and phosphatases (KPP) and polynucleotides which identify and encode KPP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of KPP.
PCT/US2003/013124 2002-04-24 2003-04-24 Kinases and phosphatases Ceased WO2003091419A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003231531A AU2003231531A1 (en) 2002-04-24 2003-04-24 Kinases and phosphatases

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US37553902P 2002-04-24 2002-04-24
US60/375,539 2002-04-24
US37818102P 2002-05-02 2002-05-02
US60/378,181 2002-05-02
US38318202P 2002-05-24 2002-05-24
US60/383,182 2002-05-24

Publications (2)

Publication Number Publication Date
WO2003091419A2 WO2003091419A2 (en) 2003-11-06
WO2003091419A3 true WO2003091419A3 (en) 2004-08-19

Family

ID=29273640

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/013124 Ceased WO2003091419A2 (en) 2002-04-24 2003-04-24 Kinases and phosphatases

Country Status (2)

Country Link
AU (1) AU2003231531A1 (en)
WO (1) WO2003091419A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050227228A1 (en) 2001-06-05 2005-10-13 Lori Friedman Map3ks as modifiers of the p53 pathway and methods of use
JP2004532638A (en) * 2001-06-05 2004-10-28 エクセリクシス・インコーポレイテッド MAP3Ks as Modifiers of the p53 Pathway and Methods of Use
WO2005085466A2 (en) * 2004-03-09 2005-09-15 Bayer Healtcare Ag Diagnostic and therapeutics for diseases associated with rho-associated protein kinase 2 (rock2)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001066594A2 (en) * 2000-03-06 2001-09-13 Sugen, Inc. Human protein kinases and protein kinase-like enzymes

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001066594A2 (en) * 2000-03-06 2001-09-13 Sugen, Inc. Human protein kinases and protein kinase-like enzymes

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
LEE A.M. ET AL: "Cloning of m-ehk2 from the murine inner ear, an eph family receptor tyrosine kinase expressed in the developing and adult cochlea", DNA AND CELL BIOLOGY, vol. 15, no. 10, 1996, pages 817 - 825, XP001122012 *

Also Published As

Publication number Publication date
AU2003231531A1 (en) 2003-11-10
WO2003091419A2 (en) 2003-11-06
AU2003231531A8 (en) 2003-11-10

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