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WO2003088997A3 - Reduction des reactions immunitaires indesirables - Google Patents

Reduction des reactions immunitaires indesirables Download PDF

Info

Publication number
WO2003088997A3
WO2003088997A3 PCT/NL2003/000297 NL0300297W WO03088997A3 WO 2003088997 A3 WO2003088997 A3 WO 2003088997A3 NL 0300297 W NL0300297 W NL 0300297W WO 03088997 A3 WO03088997 A3 WO 03088997A3
Authority
WO
WIPO (PCT)
Prior art keywords
reduction
induction
immune reactions
unwanted immune
adrenergic agonist
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/NL2003/000297
Other languages
English (en)
Other versions
WO2003088997A2 (fr
Inventor
Jacoba Johanna Heijnen
Anna Maria Agnes Ant Kavelaars
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universiteit Utrecht Holding BV
UMC Utrecht Holding BV
Original Assignee
Universiteit Utrecht Holding BV
UMC Utrecht Holding BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universiteit Utrecht Holding BV, UMC Utrecht Holding BV filed Critical Universiteit Utrecht Holding BV
Priority to AU2003228133A priority Critical patent/AU2003228133A1/en
Publication of WO2003088997A2 publication Critical patent/WO2003088997A2/fr
Publication of WO2003088997A3 publication Critical patent/WO2003088997A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Cette invention relève du domaine des produits pharmaceutiques et de la thérapie. Cette invention concerne des moyens et des méthodes permettant d'améliorer l'induction de la tolérance pour le traitement de maladies auto-immunes, de réactions d'hypersensibilité retardée et/ou de rejet de greffe et/ou de réactions du greffon contre l'hôte et/ou de réactions allergiques. Selon cette invention, l'administration par voie mucosale ou dermique d'un agoniste β2-adrénergique améliore considérablement l'induction de la tolérance envers l'administration d'antigènes. Cette invention concerne également des compositions pharmaceutiques renfermant un agoniste β2-adrénergique et un antigène, ainsi que l'utilisation de ces compositions.
PCT/NL2003/000297 2002-04-22 2003-04-22 Reduction des reactions immunitaires indesirables Ceased WO2003088997A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003228133A AU2003228133A1 (en) 2002-04-22 2003-04-22 Reduction of unwanted immune reactions

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02076600 2002-04-22
EP02076600.2 2002-04-22

Publications (2)

Publication Number Publication Date
WO2003088997A2 WO2003088997A2 (fr) 2003-10-30
WO2003088997A3 true WO2003088997A3 (fr) 2003-12-31

Family

ID=29225701

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/NL2003/000297 Ceased WO2003088997A2 (fr) 2002-04-22 2003-04-22 Reduction des reactions immunitaires indesirables

Country Status (2)

Country Link
AU (1) AU2003228133A1 (fr)
WO (1) WO2003088997A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY147864A (en) 2005-04-13 2013-01-31 Astion Dev As Beta-2 adrenoceptor agonists for treating connective tissue diseases of the skin
JP5705113B2 (ja) 2008-08-15 2015-04-22 サーカッシア リミテッド Ｉｌ−１０産生の刺激のためのアレルゲン由来のｔ細胞抗原
PL2153841T5 (pl) 2008-08-15 2016-09-30 Circassia Ltd Szczepionka zawierająca peptydy Amb a 1 do zastosowania w leczeniu alergii na ambrozję
BRPI1008802A2 (pt) 2009-02-05 2016-03-08 Circassia Ltd composição, vetor e formulação farmacêutica para o uso na prevenção ou tratamento de alergia a pólen de grama por tolerização, produto, e, método in vitro para determinar se as células t reconhecem uma composição
CN115645374B (zh) * 2022-12-25 2024-04-26 山东理工职业学院 一种硫酸沙丁胺醇片的制备方法

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
COBELENS PIETER M ET AL: "The beta2-adrenergic agonist salbutamol potentiates oral induction of tolerance, suppressing adjuvant arthritis and antigen-specific immunity.", JOURNAL OF IMMUNOLOGY, vol. 169, no. 9, 1 November 2002 (2002-11-01), pages 5028 - 5035, XP002259433, ISSN: 0022-1767 (ISSN print) *
FERMIN Z ET AL: "Salbutamol as an adjuvant for nasal vaccination", VACCINE, BUTTERWORTH SCIENTIFIC. GUILDFORD, GB, vol. 17, no. 15-16, 9 April 1999 (1999-04-09), pages 1936 - 1941, XP004165041, ISSN: 0264-410X *
KONDO NAOMI ET AL: "Inhibition of interferon-gamma production from lymphocytes stimulated with food antigens by a beta-2-agonist, procaterol, in patients with food-sensitive atopic dermatitis.", JOURNAL OF INVESTIGATIONAL ALLERGOLOGY & CLINICAL IMMUNOLOGY, vol. 7, no. 4, 1997, pages 225 - 228, XP008008273, ISSN: 1018-9068 *
OHUCHI K ET AL: "MECHANISM OF ANTIANAPHYLACTIC ACTION OF BETA-AGONISTS IN ALLERGIC INFLAMMATION OF AIR POUCH TYPE IN RATS", INTERNATIONAL ARCHIVES OF ALLERGY AND APPLIED IMMUNOLOGY, vol. 82, no. 1, 1987, pages 26 - 32, XP008008275, ISSN: 0020-5915 *

Also Published As

Publication number Publication date
AU2003228133A8 (en) 2003-11-03
AU2003228133A1 (en) 2003-11-03
WO2003088997A2 (fr) 2003-10-30

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