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WO2003084477A3 - Mammalian cdr mimetibodies, compositions, methods and uses - Google Patents

Mammalian cdr mimetibodies, compositions, methods and uses Download PDF

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Publication number
WO2003084477A3
WO2003084477A3 PCT/US2003/009139 US0309139W WO03084477A3 WO 2003084477 A3 WO2003084477 A3 WO 2003084477A3 US 0309139 W US0309139 W US 0309139W WO 03084477 A3 WO03084477 A3 WO 03084477A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
cdr
compositions
mimetibodies
mimetibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2003/009139
Other languages
French (fr)
Other versions
WO2003084477A2 (en
Inventor
George A Heavner
David M Knight
Bernard J Scallon
John Ghrayeb
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Biotech Inc
Original Assignee
Centocor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centocor Inc filed Critical Centocor Inc
Priority to EP03718053A priority Critical patent/EP1572079A4/en
Priority to AU2003222069A priority patent/AU2003222069A1/en
Publication of WO2003084477A2 publication Critical patent/WO2003084477A2/en
Anticipated expiration legal-status Critical
Publication of WO2003084477A3 publication Critical patent/WO2003084477A3/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/524—Thrombopoietin, i.e. C-MPL ligand
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2318/00—Antibody mimetics or scaffolds
    • C07K2318/10—Immunoglobulin or domain(s) thereof as scaffolds for inserted non-Ig peptide sequences, e.g. for vaccination purposes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention relates to at least one novel EPO human CDR mimetibody or specified portion or variant, including isolated nucleic acids that encode at least one CDR mimetibody or specified portion or variant, CDR mimetibody or specified portion or variants, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.
PCT/US2003/009139 2002-03-29 2003-03-24 Mammalian cdr mimetibodies, compositions, methods and uses Ceased WO2003084477A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP03718053A EP1572079A4 (en) 2002-03-29 2003-03-24 Mammalian cdr mimetibodies, compositions, methods and uses
AU2003222069A AU2003222069A1 (en) 2002-03-29 2003-03-24 Mammalian cdr mimetibodies, compositions, methods and uses

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36879102P 2002-03-29 2002-03-29
US60/368,791 2002-03-29

Publications (2)

Publication Number Publication Date
WO2003084477A2 WO2003084477A2 (en) 2003-10-16
WO2003084477A3 true WO2003084477A3 (en) 2005-09-09

Family

ID=28791903

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/009139 Ceased WO2003084477A2 (en) 2002-03-29 2003-03-24 Mammalian cdr mimetibodies, compositions, methods and uses

Country Status (3)

Country Link
EP (1) EP1572079A4 (en)
AU (1) AU2003222069A1 (en)
WO (1) WO2003084477A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108777951B (en) * 2016-01-13 2021-11-05 瑞泽恩制药公司 Non-human animals having immunoglobulin heavy chain variable regions comprising engineered diversity clusters and uses thereof

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US11752258B2 (en) 2017-02-17 2023-09-12 Amgen Inc. Drug delivery device with sterile fluid flowpath and related method of assembly
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Citations (1)

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WO1994018221A1 (en) * 1993-02-02 1994-08-18 The Scripps Research Institute Methods for producing polypeptide binding sites

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006504406A (en) * 2002-06-28 2006-02-09 セントカー・インコーポレーテツド Mammalian CH1-deficient mimetibodies, compositions, methods and uses

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
WO1994018221A1 (en) * 1993-02-02 1994-08-18 The Scripps Research Institute Methods for producing polypeptide binding sites

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1572079A4 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108777951B (en) * 2016-01-13 2021-11-05 瑞泽恩制药公司 Non-human animals having immunoglobulin heavy chain variable regions comprising engineered diversity clusters and uses thereof

Also Published As

Publication number Publication date
AU2003222069A1 (en) 2003-10-20
EP1572079A2 (en) 2005-09-14
WO2003084477A2 (en) 2003-10-16
AU2003222069A8 (en) 2003-10-20
EP1572079A4 (en) 2006-09-06

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