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WO2003080617A8 - Pyrazolopyrimidine derivatives - Google Patents

Pyrazolopyrimidine derivatives

Info

Publication number
WO2003080617A8
WO2003080617A8 PCT/EP2003/003196 EP0303196W WO03080617A8 WO 2003080617 A8 WO2003080617 A8 WO 2003080617A8 EP 0303196 W EP0303196 W EP 0303196W WO 03080617 A8 WO03080617 A8 WO 03080617A8
Authority
WO
WIPO (PCT)
Prior art keywords
compounds
pyrazolopyrimidine derivatives
pyrazolopyrimidine
derivatives
gsk
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2003/003196
Other languages
French (fr)
Other versions
WO2003080617A1 (en
Inventor
Jason Witherington
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Priority to AU2003226725A priority Critical patent/AU2003226725A1/en
Publication of WO2003080617A1 publication Critical patent/WO2003080617A1/en
Publication of WO2003080617A8 publication Critical patent/WO2003080617A8/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

A compound of formula (I),or a salt thereof, or a solvate thereof, wherein, R1, R2 and R3 are as defined in the specification, a process for preparing such compounds, a pharmaceutical composition comprising such compounds and the use of such compounds or the manufacture of a medicament for the treatment of conditions associated with a need for the inhibition of GSK-3. .
PCT/EP2003/003196 2002-03-27 2003-03-25 Pyrazolopyrimidine derivatives Ceased WO2003080617A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003226725A AU2003226725A1 (en) 2002-03-27 2003-03-25 Pyrazolopyrimidine derivatives

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0207246.0A GB0207246D0 (en) 2002-03-27 2002-03-27 Novel compounds
GB0207246.0 2002-03-27

Publications (2)

Publication Number Publication Date
WO2003080617A1 WO2003080617A1 (en) 2003-10-02
WO2003080617A8 true WO2003080617A8 (en) 2003-11-13

Family

ID=9933830

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2003/003196 Ceased WO2003080617A1 (en) 2002-03-27 2003-03-25 Pyrazolopyrimidine derivatives

Country Status (3)

Country Link
AU (1) AU2003226725A1 (en)
GB (1) GB0207246D0 (en)
WO (1) WO2003080617A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2620333A1 (en) 2005-08-26 2007-03-01 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
EP2258357A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis with acetylcholinesterase inhibitor
JP2009512711A (en) 2005-10-21 2009-03-26 ブレインセルス，インコーポレイティド Regulation of neurogenesis by PDE inhibition
US20070112017A1 (en) 2005-10-31 2007-05-17 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
AU2007219509A1 (en) * 2006-01-18 2007-09-07 Siena Biotech S.P.A Modulators of alpha7 nicotinic acetylcholine receptors and therapeutic uses thereof
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
EP2382975A3 (en) 2006-05-09 2012-02-29 Braincells, Inc. Neurogenesis by modulating angiotensin
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5593997A (en) * 1995-05-23 1997-01-14 Pfizer Inc. 4-aminopyrazolo(3-,4-D)pyrimidine and 4-aminopyrazolo-(3,4-D)pyridine tyrosine kinase inhibitors
WO2001081345A1 (en) * 2000-04-20 2001-11-01 Mitsubishi Pharma Corporation Aromatic amide compounds
WO2002024694A1 (en) * 2000-09-22 2002-03-28 Smithkline Beecham, P.L.C. Pyrazolopyridines and pyrazolopyridazines as antidiabetics
WO2002050073A1 (en) * 2000-12-19 2002-06-27 Smithkline Beecham P.L.C. Pyrazolo[3,4-c]pyridines as gsk-3 inhibitors
GB0100621D0 (en) * 2001-01-10 2001-02-21 Vernalis Res Ltd Chemical compounds VI

Also Published As

Publication number Publication date
GB0207246D0 (en) 2002-05-08
AU2003226725A8 (en) 2003-10-08
AU2003226725A1 (en) 2003-10-08
WO2003080617A1 (en) 2003-10-02

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