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WO2003068301A1 - Canule nasale a double fonction - Google Patents

Canule nasale a double fonction Download PDF

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Publication number
WO2003068301A1
WO2003068301A1 PCT/IL2003/000117 IL0300117W WO03068301A1 WO 2003068301 A1 WO2003068301 A1 WO 2003068301A1 IL 0300117 W IL0300117 W IL 0300117W WO 03068301 A1 WO03068301 A1 WO 03068301A1
Authority
WO
WIPO (PCT)
Prior art keywords
lumen
cannula
gas
subject
lumens
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IL2003/000117
Other languages
English (en)
Inventor
Ron Porat
Joshua Coleman
Leonard F. Czuba
Jason Billig
Steven R. Remy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oridion Medical 1987 Ltd
Original Assignee
Oridion Medical 1987 Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oridion Medical 1987 Ltd filed Critical Oridion Medical 1987 Ltd
Priority to AU2003207984A priority Critical patent/AU2003207984A1/en
Publication of WO2003068301A1 publication Critical patent/WO2003068301A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/06—Respiratory or anaesthetic masks
    • A61M16/0666—Nasal cannulas or tubing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/06—Head
    • A61M2210/0625—Mouth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/40—Respiratory characteristics
    • A61M2230/43—Composition of exhalation

Definitions

  • the present invention relates to nasal and oral/nasal cannulae, especially those having the dual function of collecting exhaled breath for analysis and supplying oxygen to a subject.
  • nasal and oral/nasal cannula provides exhaled breath collection, generally to enable the subject's breath to be analyzed for carbon dioxide content, and also simultaneously supplies oxygen to the subject.
  • the breath collection can be performed at the nose or at the nose and the mouth.
  • Such cannulae are known as dual function cannulae, and are characterized in that they are of dual lumen design, one lumen for collection and the other for supply.
  • a number of prior art examples are described in US Patent No. 6,422,240 for "Oral/Nasal Cannula" to G. Levitsky et al., hereby incorporated by reference in its entirety.
  • the morphologies of the collection and supply lumens in such dual parameter cannulae are generally very dissimilar.
  • the oxygen supply lumen should be capable of providing flow rates of 5 liters per minute, or even more, with typically used levels being 2-3 1/min, while breath collection flow rates as low as 50 ml/min are required.
  • the breath collection lines should have small diameters in order to provide small dead space in the line and fast response times, as further described in the above mentioned U.S. Patent No. 6,422,240. This difference is one of the constraints that influence the way in which such cannulae may be constructed.
  • Prior art dual parameter cannulae are generally manufactured by one of three methods, as follows:
  • Cannulae produced by this method are available from Salter Laboratories, Inc., of Arvin, CA, and are called the Salter Sampling Cannula with Simultaneous O 2 Delivery, model 4002 being a nasal cannula, and 4003 being an oral nasal cannula.
  • Such cannulae are comparatively large and cumbersome, since it is difficult to fit separate lumens with different morphology together in a small, compact package, without compromising their individual structural requirements based on their respective functional needs. Furthermore, the gluing process adds an additional manufacturing step, thereby probably increasing the manufacturing costs of the device which, like medical disposables in general, is very cost sensitive.
  • An injection molding process is used. Such a process is generally limited by the capabilities of injection molding, such as the need to have almost straight geometric designs, and the difficulty of manufacturing reentrant parts, namely, those parts having a section distant from the opening with a diameter larger than the diameter at the neck of the opening itself. This is generally a requirement of cannula lumens, whose neck connections are generally significantly smaller than the dimensions at the inner sections. Furthermore, it is very difficult with generally used injection molding processes and mold design, to embed one lumen within the external contours of another.
  • the body of the cannula should preferably have a profile which curves to match the profile of the face of a user, and the nasal prongs should also be curved to match the angle of entry of a user's nostrils.
  • This combination is not easy to execute by injection molding.
  • Examples of cannulae produced, to the best of the applicant's understanding, by this method, are available from Hudson Respiratory Care Incorporated of Temecula, CA, under the trade name "Softech Bi-Flo (TM) Cannula", models 1843, 1844 and 1845. These cannulae, however, have generally simple geometric forms, possibly because of the above- mentioned difficulties. 3.
  • the cannula is divided laterally and symmetrically down the center, and each side fulfils a separate one of the dual functions.
  • one nostril prong is used for breath collection, while the second nostril prong is used for oxygen supply.
  • Such a cannula because of its simple and open design, can be made in a single unit by dip molding with all of the advantages of this process, namely smooth outer contours of the part, and soft pliable materials, as is discussed hereinbelow.
  • Such cannulae are available from the Salter Laboratories, Inc., of Arvin, CA, and are called the "Salter Divided Cannula" 4700 series.
  • such a split function cannula suffers from disadvantages in use.
  • a further method known as rotational molding, is simpler than conventional injection molding, in that there are no internal cores, but is limited to use on the outer features only of the product. This technology would thus be limited to a single lumen or chamber design, a dual lumen product being virtually impossible to produce in one step by this method.
  • the present invention seeks to provide a new dual function cannula, which provides compactness, a low internal volume, ergonomic comfort and low production cost without detracting from the functional efficiency of the cannula by compromising the individual morphological requirements of each functional component.
  • the cannula of the present invention can be provided in nasal or nasal/oral preferred embodiments, and includes collection and supply functions, integrated into one cannula without compromising their operational functionality.
  • the cannula preferably incorporates the single junction construction as disclosed in the above-mentioned U.S. Patent No. 6,422,240, whereby all component parts of the breath collection lumen meet at a single junction.
  • the present invention is not limited to cannulae constructed with single junction construction, but is equally applicable to other dual function cannula designs.
  • a cannula which provides dual functionality of gas collection and supply, and wherein each of the two functionalities are applied essentially symmetrically to the user relative to the facial center line, such that gas is supplied and collected essentially equally to and from both nostrils.
  • the dual functions of the cannula are integrated into a single body shape while maintaining minimum possible external dimensions.
  • the cannula construction is such that the efficiency of each of the collection and supply functions is not compromised.
  • a rounded cross section, bi-lumen body the first lumen, preferably having a larger diameter, being preferably utilized for oxygen supply and essentially comprising the major part of the entire cannula body, and the second lumen, having a smaller diameter and preferably serving as the breath collection lumen, being embedded into one side of the first lumen in a manner that retains the external generally rounded shape of the cannula.
  • the gas supply lumen is in the provision of oxygen for the subject, and is so generally described in this specification, the gas delivered could equally well be an anaesthetic gas such as nitrous oxide, or any other gas which is to be supplied to the subject.
  • the dual function cannula of the present invention can be provided as a nasal cannula, in which case a pair of symmetrically located nasal prongs are preferably added to the collection lumen, or as an oral/nasal cannula, in which case, an oral prong is also preferably added to the collection lumen.
  • the oxygen supply and breath collection tubes are preferably connected to the cannula at its sides, and constitute the anchoring points for tying the cannula to the subject's face.
  • These requirements essentially mean that the lateral asymmetry of the supply and collection lines can be incorporated into the above-mentioned compact design by providing separate lumens that overlap in space. This means that no plane can be defined in the cannula morphology in which the supply lumen is entirely on one side of it and the collection lumen is on the other side
  • all of the above requirements of the cannula of the present invention can be provided by means of a dip-molding process, preferably performed in one dipping step.
  • the morphological asymmetry of the lumens is realized by using dipping mandrels that overlap relative to any axis chosen.
  • the use of such a dip molding process also easily enables the provision of lumens that are significantly larger at their inner sections, at the center of the cannula, than at the lumen ends, where the gas supply or collection tubes are attached. This requires the use of mandrels having dimensions at the inner parts of the cannula larger than those of the exit port dimension through which the mandrel is to be removed.
  • Such a dip molding process allows the cannula to be made of a soft and pliable plastic material, such as plastisol, thus enabling such mandrels to be withdrawn from the dipped part without damaging or deforming the part.
  • a soft pliable material has the added required properties of wearing comfort for the patient, both to the facial skin and to the nasal septum.
  • dip molding In contrast to injection or rotational molding, dip molding, because of the nature of the material application method by dipping, is able to provide rounded and smooth external features without any sharp protrusions or corners. This is because tooling mandrels utilized in dip molding are of the positive form, forming only the internal features of the part, whereas in injection and rotational molding, a negative form is used, resulting in every imperfection of the tool being reproduced on the outside of the cannula or molded part. Thus, dip molding results in accurate intemal dimensions combined with the soft external features required in a cannula, as discussed above.
  • the cannulae of the present invention can also preferably be constructed by such injection molding techniques.
  • a nasal cannula comprising a first lumen adapted for supply of gas to the nostrils of a subject, and a second lumen adapted for collection of gas from the nostrils of the subject, the first and the second lumens having a common wall along at least part of their lengths, one of the lumens being contained at least partially within the cross section of the other, the first lumen having outlets disposed such that it supplies gas essentially equally to both nostrils of the subject, and the second lumen having inlets disposed such that it collects gas essentially equally from both nostrils of the subject.
  • an oral/nasal cannula comprising a first lumen adapted for supply of gas to a subject, and a second lumen adapted for collection of gas from the nostrils and mouth of the subject, the first and second lumens having a common wall along at least part of their lengths, one of the lumens being contained at least partially within the cross section of the other, the first lumen having outlets disposed such that it supplies gas essentially equally to both nostrils of the subject, and the second lumen having inlets disposed such that it collects gas essentially equally from both nostrils of the subject.
  • one of the lumens may preferably be of cross section generally smaller than that of the other.
  • either or both of the lumens may have a cross section which is smaller at its outer end than at its center.
  • the lumens may preferably be shaped such that the cannula conforms to the facial profile of the subject.
  • either of the above mentioned cannulae may preferably be dip molded.
  • a nasal cannula comprising a gas supply lumen having outlets for supply of gas to both nostrils of a subject, the supply lumen having its input on one lateral side of the cannula, and a gas collection lumen having inlets for collection of gas from both nostrils of the subject, the collection lumen having its output on the lateral side of the cannula opposite to that of the supply lumen, the lumens having a common wall, and the supply lumen having a cross section generally larger than that of the collection lumen.
  • an oral/nasal cannula comprising a gas supply lumen having outlets for supply of gas to a subject, the supply lumen having its input on one lateral side of the cannula, and a gas collection lumen having inlets for collection of gas from both nostrils and mouth of the subject, the collection lumen having its output on the lateral side of the cannula opposite to that of the supply lumen, the lumens having a common wall, and the supply lumen having a cross section generally larger than that of the collection lumen.
  • the lumens may preferably be such that the supply of gas is provided essentially equally to both nostrils of the subject and the collection of gas is performed essentially equally from both nostrils of the subject.
  • one of the lumens may preferably be contained at least partially within the cross section of the other.
  • either or both of the lumens may have a cross section which is smaller at its outer end than at its center.
  • the lumens may preferably be shaped such that the cannula conforms to the facial profile of the subject.
  • that part of the cannula comprising at least the gas supply lumen and the gas collection lumen may preferably be dip molded as one piece.
  • the outlets for supply of gas to both nostrils of a subject are preferably in the form of an array of holes uniformly disposed beneath the subject's nostrils.
  • the outlets, as described throughout this specification, and as claimed may be of any other form or shape that provides supply of gas essentially equally to both nostrils.
  • the inlets for collection of gas from both nostrils of the subject are preferably in the form of a pair of nasal prongs.
  • the inlets, as described throughout this specification, and as claimed may be of any other form or shape that provides collection of gas essentially equally from both nostrils.
  • the supply outlets could be nasal prongs and the collection inlets an array of holes, though such an arrangement is likely to be less efficient than the reverse arrangement.
  • Fig. 1 is a simplified pictorial illustration of a portion of a cannula constructed and operative in accordance with a preferred embodiment of the present invention
  • Figs. 2A, 2B, 2C and 2D are sectional illustrations taken along the lines VA - VA, VB - VB, VC - VC and VD - VD in Fig. 1;
  • FIG. 3 is another simplified pictorial illustration of the portion of the cannula shown in Figs. 1 - 2D taken from a different angle;
  • Figs. 4A, 4B, and 4C are sectional illustrations taken along the lines VTLA - VHA, VUB - Vim and VTC - V ⁇ C in Fig. 3;
  • Figs. 5 A and 5B are pictorial illustrations of the portions of the cannula shown in Figs. 1 - 4D;
  • FIGs. 6A and 6B are pictorial illustrations of portions of a cannula constructed and operative in accordance with another preferred embodiment of the present invention.
  • Fig. 7 is a simplified pictorial illustration of a portion of the cannula shown in Figs 6 A and 6B;
  • Figs. 8A and 8B are sectional illustrations taken along the lines XIA - XIA, and X 3 - XIB in Fig. 7;
  • Figs. 9A, 9B and 9C are simplified illustrations of mandrel examples as used in dip molding of a cannula in accordance with a preferred embodiment of the present invention.
  • Fig. 1 illustrates a nasal cannula, constructed and operative according to a preferred embodiment of the present invention.
  • the cannula preferably includes nasal prongs 160 and 162, which communicate with a breath collection lumen 164.
  • the cannula has a uni-junction construction, wherein nasal prongs 160 and 162 and breath collection lumen 164 all meet at a single junction, as will be shown in detail in Figs. 4B and 4C hereinbelow.
  • the single junction and its associated lumen and prongs are embedded in the side of an oxygen supply lumen 166.
  • the oxygen supply lumen 166 is suitable for providing a flow of oxygen to a subject preferably via a plurality of apertures 168, without unduly interfering with the waveform or concentration of the sampled breath. If the cannula is manufactured by a molding process, the apertures 168 may be generated as part of the molding process, but it may generally be simpler to drill them in an additional, post molding operation.
  • FIG. 2A to 5B schematically illustrate different isometric views and cut away cross-sectional views of nasal cannulae according to preferred embodiments of the present invention, the figures illustrating the internal and external structure and features of the cannulae of the present invention.
  • Figs. 2A, 2B, 2C and 2D are cross-sectional views of the cannula shown in Fig. 1, taken along the lines VA - VA, VB - VB, VC - VC and VD - VD.
  • Fig. 3 is another isometric view of the cannula shown in Fig. 1, viewed from above to show the array of apertures 168 supplying gas as uniformly as possible to both nostrils of a subject wearing the cannula.
  • Figs. 4A, 4B, and 4C are sectional views taken along the lines VHA - VILA, VTJB - Vim and V ⁇ C - VIIC of the cannula shown in Fig. 3.
  • Figs. 5 A and 5B are more isometric views of the cannula shown in Figs. 1 and 3, taken from different angles in order to more clearly illustrate the structure of the cannula.
  • the previous figures clearly illustrate the asymmetric morphology of the cannula around its lateral centerline, in addition to the symmetric nature of the operation of each functionality.
  • the functional symmetry of the oxygen supply providing essentially equal supply to both nostrils is maintained even though the shape of the lumen is asymmetric relative to the cannula, the supply being from one side.
  • the functional symmetry of the breath collection system collecting essentially equally from both nostrils, is maintained even though the shape of the lumen is asymmetric relative to the cannula, the collection being from one side.
  • the input oxygen supply line to the cannula, and the output breath collection line from the cannula are symmetrically disposed relative to the lateral center line of the cannula, and both are suitably angled to match the profile of the user's facial features.
  • oxygen supply lumen 166 is a generally larger diameter lumen, making up the major part of the diameter of the cannula body, while breath collection lumen 164 is generally smaller in diameter than oxygen supply lumen 166.
  • the breath collection lumen 164 does not have to be connected with both nasal prongs 160 and 162 at a single junction. It is evident from Figs. 1 to 5B that although the cannula is not symmetrical, the functionality of the collection system is symmetric, in that there are identical prongs in each nostril, and the collection point is symmetric to the two nasal prongs. Likewise, as is clearly seen in Fig. 3, the oxygen delivery to the nostrils takes place through holes 168, which are symmetrically drilled relative to the nostril positions of the subject, such that each nostril is provided with essentially equal quantities of gas.
  • the structure of the cannula has the advantage of providing added mechanical stability to the cannula, as compared to prior art cannulae for nasal collection only, wherein the small diameter collection lumen has little support.
  • Figs. 6A to 8B illustrate another cannula, constructed according to another preferred embodiment of the present invention, which includes nasal prongs 260 and 262 and oral prong 263 which communicate with a breath collection lumen 264.
  • the cannula preferably has a uni-junction construction, wherein nasal prongs 260 and 262 and oral prong 263 and breath collection lumen 264 all meet at a single junction, as shown in Fig. 8B.
  • the single junction and its associated lumen and prongs are embedded in the side of an oxygen supply lumen 266.
  • the oxygen supply lumen 266 is suitable for providing a flow of oxygen to a subject via a plurality of apertures 268, without unduly interfering with the waveform or concentration of the sampled breath.
  • Apertures 268 may be generated as part of the molding process, but are preferably drilled in an additional, post molding operation.
  • Figs. 6A to 8B illustrate the asymmetric morphology of the cannula around its lateral center line, in addition to the symmetric nature of the operation of each functionality.
  • the functional symmetry of the oxygen supply relative to the nostrils is maintained even though the shape of the lumen is asymmetric relative to the cannula, the supply being from one side.
  • the input oxygen supply line to the cannula, and the output breath collection line from the cannula are symmetrically disposed relative to the lateral center line of the cannula, and both are suitably angled to match the profile of the user's facial features.
  • oxygen supply lumen 266 is a large diameter lumen, making up the major part of the diameter of the cannula body, while breath collection lumen 264 is smaller in diameter than oxygen supply lumen 266.
  • the breath collection lumen 264 does not have to be connected with nasal prongs 260 and 262 and oral prong 263 at a single junction. It is evident from Figs. 6A to 8B that although the cannula is not symmetrical, the functionality of the collection system is symmetric, in that there are identical prongs in each nostril, and the collection point is symmetric to the two nasal prongs.
  • a first lumen defining mandrel 300 is preferably formed as a generally elongate element having an irregularly shaped recess 302 formed therein.
  • a second lumen forming mandrel 304 is preferably formed as a generally elongate element having a curved nasal prong joining lumen defining portion 306 attached thereto.
  • mandrels 300 and 304 are mutually positioned such that the mandrel 304 and, specifically, the curved nasal prong joining lumen defining portion 306 is located at least partially within recess 302, in non-touching relationship with mandrel 300.
  • a pair of nasal prong defining mandrels 308 and 310 are arranged in touching relationship with ends of the curved nasal prong joining lumen portion 306, as seen in both Figs. 9B and 9C. If an oral/nasal cannula is to be formed, an additional mandrel for the oral prong (not shown) is required.
  • Mandrels curved in all three axes are required in order to provide the appropriate shapes for the various lumens and prongs of the cannula, so that they function correctly and ergonomically match their intended sampling regions.
  • the mandrels preferably have small outer diameters, corresponding to the small dimensions of the cannulae, and also preferably have flared shapes, as required by the ergonomic feature design, since the end opening dimensions of the lumens are generally smaller than the inner dimensions thereof.
  • the nasal prongs 260 and 262 and oral prong 263 and the breath collection lumen 264 are not in fluid communication with the oxygen supply lumen 266, being separated by walls including an internal common wall.
  • a common wall is possibly realized, when the cannula is produced using dip molding technology, by non-touching relative spatial positioning of mandrels during the dip molding of the cannula, as depicted in Figs. 9A-9C hereinabove.
  • the wall structure is produced favorably by the dip molding method, as the material flows readily into the area between the mandrels which were located in the channels of the cannula.
  • oxygen supply lumen 166 and breath collection lumen 164 are formed by mandrels 300 and 304, respectively.

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  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Otolaryngology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Respiratory Apparatuses And Protective Means (AREA)

Abstract

La présente invention concerne une canule compacte nasale ou nasale/orale comprenant des lumières d'alimentation en gaz (164) et de collecte de gaz (166) séparées, présentant une paroi commune. Cette canule assure une double fonction de collecte de gaz et d'alimentation en gaz, appliquées de manière égale dans les deux narines d'un sujet. Les lumières de collecte et d'alimentation de la canule présentent des dimensions différentes et peuvent être intégrées l'une partiellement à l'intérieur de l'autre.
PCT/IL2003/000117 2002-02-15 2003-02-13 Canule nasale a double fonction Ceased WO2003068301A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003207984A AU2003207984A1 (en) 2002-02-15 2003-02-13 Dual function nasal cannula

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35735902P 2002-02-15 2002-02-15
US60/357,359 2002-02-15

Publications (1)

Publication Number Publication Date
WO2003068301A1 true WO2003068301A1 (fr) 2003-08-21

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PCT/IL2003/000117 Ceased WO2003068301A1 (fr) 2002-02-15 2003-02-13 Canule nasale a double fonction

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WO (1) WO2003068301A1 (fr)

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1834660A1 (fr) * 2006-03-17 2007-09-19 Innosuisse Management AG Appareil pour introduire de l'air respiratoire directement dans le nez d'un utilisateur
EP1849491A1 (fr) * 2006-04-25 2007-10-31 Oridion Medical 1987 Ltd. Cannule orale et nasale
WO2011029073A1 (fr) 2009-09-03 2011-03-10 Breathe Technologies, Inc. Procédés, systèmes et dispositifs non effractifs de ventilation nasale comprenant une interface non fermée avec espace libre pour l’injecteur
EP1694193A4 (fr) * 2003-12-05 2011-09-07 Salter Labs Dispositif d'apport, d'echantillonnage et/ou de detection d'une canule nasale et orale
EP2374494A3 (fr) * 2005-01-07 2012-02-22 TNI medical AG Lunette à air, embout nasal, élément en Y et procédé associé
EP1845841A4 (fr) * 2004-12-28 2012-04-04 Oridion Medical 1987 Ltd Catheter d'echantillonnage capnographique
US9044565B2 (en) 2008-10-30 2015-06-02 Oridion Medical (1987) Ltd. Oral-nasal cannula system enabling CO2 and breath flow measurement
US9132250B2 (en) 2009-09-03 2015-09-15 Breathe Technologies, Inc. Methods, systems and devices for non-invasive ventilation including a non-sealing ventilation interface with an entrainment port and/or pressure feature
EP2928532A4 (fr) * 2012-12-07 2016-06-29 Parion Sciences Inc Canule nasale pour la distribution de médicaments en aérosol
WO2016157103A1 (fr) * 2015-03-31 2016-10-06 Fisher & Paykel Healthcare Limited Canule nasale
US20170232220A1 (en) * 2016-02-17 2017-08-17 Christine M. Huerta Septi-Cannula
US9962512B2 (en) 2009-04-02 2018-05-08 Breathe Technologies, Inc. Methods, systems and devices for non-invasive ventilation including a non-sealing ventilation interface with a free space nozzle feature
US9987443B2 (en) 2007-10-10 2018-06-05 Parion Sciences, Inc. Inhaled hypertonic saline delivered by a heated nasal cannula
US10335558B2 (en) 2011-06-07 2019-07-02 Parion Sciences, Inc. Methods of treatment
US10441196B2 (en) 2015-01-23 2019-10-15 Masimo Corporation Nasal/oral cannula system and manufacturing
US11154672B2 (en) 2009-09-03 2021-10-26 Breathe Technologies, Inc. Methods, systems and devices for non-invasive ventilation including a non-sealing ventilation interface with an entrainment port and/or pressure feature
US11565067B2 (en) 2013-08-09 2023-01-31 Fisher & Paykel Healthcare Limited Asymmetrical nasal delivery elements and fittings for nasal interfaces

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Publication number Priority date Publication date Assignee Title
US4106505A (en) * 1977-01-17 1978-08-15 Salter Labs., Inc. Nasal cannula assembly
US5099836A (en) * 1987-10-05 1992-03-31 Hudson Respiratory Care Inc. Intermittent oxygen delivery system and cannula
WO1992012751A1 (fr) * 1989-01-26 1992-08-06 Puritan-Bennett Corporation Canule a deux lumieres
WO2001095971A2 (fr) * 2000-06-13 2001-12-20 Scott Laboratories, Inc. Appareil et procede d'apport sans masque d'un melange gazeux a inspirer et de prelevement de gaz
US6422240B1 (en) * 1998-01-29 2002-07-23 Oridion Medical Ltd. Oral/nasal cannula

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4106505A (en) * 1977-01-17 1978-08-15 Salter Labs., Inc. Nasal cannula assembly
US5099836A (en) * 1987-10-05 1992-03-31 Hudson Respiratory Care Inc. Intermittent oxygen delivery system and cannula
WO1992012751A1 (fr) * 1989-01-26 1992-08-06 Puritan-Bennett Corporation Canule a deux lumieres
US6422240B1 (en) * 1998-01-29 2002-07-23 Oridion Medical Ltd. Oral/nasal cannula
WO2001095971A2 (fr) * 2000-06-13 2001-12-20 Scott Laboratories, Inc. Appareil et procede d'apport sans masque d'un melange gazeux a inspirer et de prelevement de gaz

Cited By (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1694193A4 (fr) * 2003-12-05 2011-09-07 Salter Labs Dispositif d'apport, d'echantillonnage et/ou de detection d'une canule nasale et orale
EP1845841A4 (fr) * 2004-12-28 2012-04-04 Oridion Medical 1987 Ltd Catheter d'echantillonnage capnographique
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