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WO2003066086A3 - Proteins involved in the regulation of energy homeostatis - Google Patents

Proteins involved in the regulation of energy homeostatis Download PDF

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Publication number
WO2003066086A3
WO2003066086A3 PCT/EP2003/001094 EP0301094W WO03066086A3 WO 2003066086 A3 WO2003066086 A3 WO 2003066086A3 EP 0301094 W EP0301094 W EP 0301094W WO 03066086 A3 WO03066086 A3 WO 03066086A3
Authority
WO
WIPO (PCT)
Prior art keywords
regulation
proteins involved
energy
homeostatis
energy homeostatis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2003/001094
Other languages
French (fr)
Other versions
WO2003066086A2 (en
Inventor
Karsten Eulenberg
Guenter Broenner
Arndt Steuernagel
Martin Meise
Thomas Haeder
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Develogen AG
Original Assignee
Develogen AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Develogen AG filed Critical Develogen AG
Priority to AU2003226973A priority Critical patent/AU2003226973A1/en
Publication of WO2003066086A2 publication Critical patent/WO2003066086A2/en
Publication of WO2003066086A3 publication Critical patent/WO2003066086A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45—Transferases (2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The present invention discloses casein kinase 1 gamma, GABARAP, PA2G4, MOCS1, CDC10, PK, calreticulin, and/or homologous proteins regulating the energy homeostasis and the metabolism of triglycerides, and polynucleotides, which identify and encode the proteins disclosed in this invention. The invention also relates to the use of these sequences in the diagnosis, study, prevention, and treatment of metabolic diseases and disorders.
PCT/EP2003/001094 2002-02-04 2003-02-04 Proteins involved in the regulation of energy homeostatis Ceased WO2003066086A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003226973A AU2003226973A1 (en) 2002-02-04 2003-02-04 Proteins involved in the regulation of energy homeostatis

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
EP02002548 2002-02-04
EP02002548.2 2002-02-04
EP02002707.4 2002-02-06
EP02002707 2002-02-06
EP02002891.6 2002-02-08
EP02002891 2002-02-08
EP02003748 2002-02-19
EP02003748.7 2002-02-19
EP02004667 2002-02-28
EP02004667.8 2002-02-28
EP02022101 2002-10-02
EP02022101.6 2002-10-02

Publications (2)

Publication Number Publication Date
WO2003066086A2 WO2003066086A2 (en) 2003-08-14
WO2003066086A3 true WO2003066086A3 (en) 2004-01-22

Family

ID=27739472

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2003/001094 Ceased WO2003066086A2 (en) 2002-02-04 2003-02-04 Proteins involved in the regulation of energy homeostatis

Country Status (2)

Country Link
AU (1) AU2003226973A1 (en)
WO (1) WO2003066086A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11286501B2 (en) 2016-04-20 2022-03-29 Centro De Investigaciones Energeticas, Medioambientales Y Tecnologicas O.A, M.P. Methods of treating or preventing pyruvate kinase deficiency
US11642422B2 (en) 2017-10-16 2023-05-09 Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas, O.A, M.P. Lentiviral vectors for delivery of PKLR to treat pyruvate kinase deficiency

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004296108A1 (en) * 2003-12-12 2005-06-23 The University Of Manitoba Methods and compounds for modulating triglyceride and VLDL secretion
CA2924393A1 (en) * 2013-09-25 2015-04-02 Institute For Systems Biology Markers for amyotrophic lateral sclerosis (als) and presymptomatic alzheimer's desease (psad)
CN105063056A (en) * 2015-09-20 2015-11-18 查文娟 Aptamer capable of being specifically combined with cancer marker calreticulin and kit

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001096547A2 (en) * 2000-06-15 2001-12-20 Incyte Genomics, Inc. Human kinases
WO2002046384A2 (en) * 2000-12-06 2002-06-13 Incyte Genomics, Inc. Kinases and phosphatases sequences, and use thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001096547A2 (en) * 2000-06-15 2001-12-20 Incyte Genomics, Inc. Human kinases
WO2002046384A2 (en) * 2000-12-06 2002-06-13 Incyte Genomics, Inc. Kinases and phosphatases sequences, and use thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JEFFERSON L S ET AL: "Glycogen synthase kinase-3 is the predominant insulin-regulated eukaryotic initiation factor 2B kinase in skeletal muscle.", THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY. ENGLAND JAN 1999, vol. 31, no. 1, January 1999 (1999-01-01), pages 191 - 200, XP002250401, ISSN: 1357-2725 *
ROHER N ET AL: "Protein kinase CK2 is altered in insulin-resistant genetically obese (fa/fa) rats", FEBS LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 437, no. 3, 23 October 1998 (1998-10-23), pages 211 - 215, XP004258526, ISSN: 0014-5793 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11286501B2 (en) 2016-04-20 2022-03-29 Centro De Investigaciones Energeticas, Medioambientales Y Tecnologicas O.A, M.P. Methods of treating or preventing pyruvate kinase deficiency
US11642422B2 (en) 2017-10-16 2023-05-09 Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas, O.A, M.P. Lentiviral vectors for delivery of PKLR to treat pyruvate kinase deficiency

Also Published As

Publication number Publication date
WO2003066086A2 (en) 2003-08-14
AU2003226973A1 (en) 2003-09-02

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