|
US4522811A
(en)
|
1982-07-08 |
1985-06-11 |
Syntex (U.S.A.) Inc. |
Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
|
|
FR2562421B1
(fr)
|
1984-04-09 |
1989-02-17 |
Sandoz Sa |
Perfectionnements a la therapie par l'interleukine
|
|
EP0169146A3
(fr)
|
1984-07-20 |
1988-07-20 |
Merck & Co. Inc. |
Anticoprs monoclonaux dirigés contre le récepteur cellulaire du rhinovirus humain
|
|
US4698420A
(en)
*
|
1985-02-25 |
1987-10-06 |
Xoma Corporation |
Antibody hybrid molecules and process for their preparation
|
|
US5077195A
(en)
*
|
1985-03-01 |
1991-12-31 |
Board Of Reagents, The University Of Texas System |
Polypeptides complementary to peptides or proteins having an amino acid sequence or nucleotide coding sequence at least partially known and methods of design therefor
|
|
US4975282A
(en)
|
1985-06-26 |
1990-12-04 |
The Liposome Company, Inc. |
Multilamellar liposomes having improved trapping efficiencies
|
|
ES2039203T3
(es)
|
1985-11-22 |
1993-09-16 |
Takeda Chemical Industries, Ltd. |
Composicion de liposomas.
|
|
GB8607679D0
(en)
|
1986-03-27 |
1986-04-30 |
Winter G P |
Recombinant dna product
|
|
US5225539A
(en)
|
1986-03-27 |
1993-07-06 |
Medical Research Council |
Recombinant altered antibodies and methods of making altered antibodies
|
|
US5869620A
(en)
|
1986-09-02 |
1999-02-09 |
Enzon, Inc. |
Multivalent antigen-binding proteins
|
|
DE3785186T2
(de)
|
1986-09-02 |
1993-07-15 |
Enzon Lab Inc |
Bindungsmolekuele mit einzelpolypeptidkette.
|
|
US5260203A
(en)
|
1986-09-02 |
1993-11-09 |
Enzon, Inc. |
Single polypeptide chain binding molecules
|
|
US4946778A
(en)
*
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
|
JP2666345B2
(ja)
|
1987-04-16 |
1997-10-22 |
武田薬品工業株式会社 |
リポソーム製剤およびその製造法
|
|
US5284931A
(en)
|
1987-05-04 |
1994-02-08 |
Dana Farber Cancer Institute |
Intercellular adhesion molecules, and their binding ligands
|
|
US5565550A
(en)
|
1987-05-04 |
1996-10-15 |
Dana Farber Cancer Institute |
Antibodies to ICAM-2, and fragments thereof
|
|
ATE128727T1
(de)
|
1987-05-04 |
1995-10-15 |
Dana Farber Cancer Inst Inc |
Interzellulare adhäsions-moleküle und deren bindungsliganden.
|
|
US5273876A
(en)
|
1987-06-26 |
1993-12-28 |
Syntro Corporation |
Recombinant human cytomegalovirus containing foreign gene
|
|
US5223409A
(en)
*
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
|
WO1990002569A1
(fr)
|
1988-09-06 |
1990-03-22 |
International Genetic Engineering, Inc. |
Production d'anticorps chimeriques murins-humains a specificite pour des antigenes de tumeurs humains
|
|
ATE125708T1
(de)
|
1988-09-28 |
1995-08-15 |
Dana Farber Cancer Inst Inc |
Interzellulare adhäsions-moleküle und deren bindungsliganden.
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
IL162181A
(en)
|
1988-12-28 |
2006-04-10 |
Pdl Biopharma Inc |
A method of producing humanized immunoglubulin, and polynucleotides encoding the same
|
|
JPH04503306A
(ja)
|
1989-02-01 |
1992-06-18 |
ザ・ジェネラル・ホスピタル・コーポレーション |
単純ヘルペスウイルス1型発現ベクター
|
|
US5665577A
(en)
|
1989-02-06 |
1997-09-09 |
Dana-Farber Cancer Institute |
Vectors containing HIV packaging sequences, packaging defective HIV vectors, and uses thereof
|
|
DK0387701T3
(da)
|
1989-03-09 |
1992-12-07 |
Boehringer Ingelheim Pharma |
Anvendelse af intercellulære adhæsionsmolekyler samt deres bindende ligander ved behandling af astma
|
|
US5081584A
(en)
*
|
1989-03-13 |
1992-01-14 |
United States Of America |
Computer-assisted design of anti-peptides based on the amino acid sequence of a target peptide
|
|
AU627591B2
(en)
|
1989-06-19 |
1992-08-27 |
Xoma Corporation |
Chimeric mouse-human km10 antibody with specificity to a human tumor cell antigen
|
|
US5324510A
(en)
|
1989-09-01 |
1994-06-28 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Use of antibodies to intercellular adhesion molecule-1 (ICAM-1) in the treatment of asthma
|
|
WO1991007418A1
(fr)
|
1989-11-13 |
1991-05-30 |
Xoma Corporation |
Anticorps a10 chimerique souris-humain avec specificite envers un antigene de cellule tumorale humaine
|
|
WO1991007493A1
(fr)
|
1989-11-13 |
1991-05-30 |
Xoma Corporation |
Anticorps murins humains chimeriques a specificite aux antigenes du vih
|
|
AU6663990A
(en)
|
1989-11-13 |
1991-05-16 |
Green Cross Corporation, The |
Chimeric mouse-human antibodies with specificity to hiv antigens
|
|
US5264618A
(en)
|
1990-04-19 |
1993-11-23 |
Vical, Inc. |
Cationic lipids for intracellular delivery of biologically active molecules
|
|
GB9009548D0
(en)
|
1990-04-27 |
1990-06-20 |
Celltech Ltd |
Chimeric antibody and method
|
|
EP0459577A3
(en)
|
1990-06-01 |
1992-08-05 |
Merck & Co. Inc. |
Microbially expressed portions of a monoclonal antibody block rhinovirus attachment to cell receptors
|
|
US5723286A
(en)
*
|
1990-06-20 |
1998-03-03 |
Affymax Technologies N.V. |
Peptide library and screening systems
|
|
US5582996A
(en)
|
1990-12-04 |
1996-12-10 |
The Wistar Institute Of Anatomy & Biology |
Bifunctional antibodies and method of preparing same
|
|
GB9105383D0
(en)
|
1991-03-14 |
1991-05-01 |
Immunology Ltd |
An immunotherapeutic for cervical cancer
|
|
US5223396A
(en)
|
1991-05-03 |
1993-06-29 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Method for detecting organ transplant rejection
|
|
CA2103059C
(fr)
|
1991-06-14 |
2005-03-22 |
Paul J. Carter |
Methode de production d'anticorps humanises
|
|
JP3540315B2
(ja)
|
1991-09-23 |
2004-07-07 |
メディカル リサーチ カウンシル |
キメラ抗体の製造−組合せアプローチ
|
|
US5716805A
(en)
|
1991-10-25 |
1998-02-10 |
Immunex Corporation |
Methods of preparing soluble, oligomeric proteins
|
|
US6027725A
(en)
|
1991-11-25 |
2000-02-22 |
Enzon, Inc. |
Multivalent antigen-binding proteins
|
|
US5932448A
(en)
|
1991-11-29 |
1999-08-03 |
Protein Design Labs., Inc. |
Bispecific antibody heterodimers
|
|
EP0571613B1
(fr)
*
|
1991-12-13 |
2003-09-17 |
Xoma Corporation |
Materiels et methodes pour preparer des domaines variables d'anticorps modifies et leurs utilisations therapeutiques
|
|
KR100254759B1
(ko)
|
1992-01-23 |
2000-05-01 |
플레믹 크리스티안 |
단량체 및 이량체 항체-단편 융합 단백질
|
|
US5330101A
(en)
|
1992-02-06 |
1994-07-19 |
Nordson Corporation |
Material changeover and anti-skin over system
|
|
US6129914A
(en)
*
|
1992-03-27 |
2000-10-10 |
Protein Design Labs, Inc. |
Bispecific antibody effective to treat B-cell lymphoma and cell line
|
|
WO1993019660A1
(fr)
|
1992-04-03 |
1993-10-14 |
Baylor College Of Medicine |
Therapie genique utilisant l'intestin
|
|
US6329507B1
(en)
|
1992-08-21 |
2001-12-11 |
The Dow Chemical Company |
Dimer and multimer forms of single chain polypeptides
|
|
US5639641A
(en)
*
|
1992-09-09 |
1997-06-17 |
Immunogen Inc. |
Resurfacing of rodent antibodies
|
|
AU5670194A
(en)
|
1992-11-20 |
1994-06-22 |
Enzon, Inc. |
Linker for linked fusion polypeptides
|
|
US5674703A
(en)
|
1992-12-02 |
1997-10-07 |
Woo; Savio L. C. |
Episomal vector systems and related methods
|
|
JP3720353B2
(ja)
*
|
1992-12-04 |
2005-11-24 |
メディカル リサーチ カウンシル |
多価および多重特異性の結合タンパク質、それらの製造および使用
|
|
US6307026B1
(en)
*
|
1992-12-10 |
2001-10-23 |
Celltech Limited |
Humanized antibodies directed against A33 antigen
|
|
US5491074A
(en)
|
1993-04-01 |
1996-02-13 |
Affymax Technologies Nv |
Association peptides
|
|
JPH09510601A
(ja)
|
1993-11-12 |
1997-10-28 |
ケース・ウエスタン・リザーブ・ユニバーシティ |
ヒト遺伝子治療用のエピソーム発現ベクター
|
|
US5928944A
(en)
|
1994-02-04 |
1999-07-27 |
The United States Of America As Represented By The Department Of Health And Human Services |
Method of adenoviral-medicated cell transfection
|
|
CA2117668C
(fr)
|
1994-03-09 |
2005-08-09 |
Izumu Saito |
Adenovirus recombinant et son mode de production
|
|
JP3348204B2
(ja)
|
1994-04-20 |
2002-11-20 |
三菱アルミニウム株式会社 |
ろう粉末付長尺物の製造方法および装置
|
|
GB9409768D0
(en)
|
1994-05-16 |
1994-07-06 |
Medical Res Council |
Trimerising polypeptides
|
|
US5604090A
(en)
|
1994-06-06 |
1997-02-18 |
Fred Hutchinson Cancer Research Center |
Method for increasing transduction of cells by adeno-associated virus vectors
|
|
US5763733A
(en)
|
1994-10-13 |
1998-06-09 |
Enzon, Inc. |
Antigen-binding fusion proteins
|
|
US5693508A
(en)
|
1994-11-08 |
1997-12-02 |
Chang; Lung-Ji |
Retroviral expression vectors containing MoMLV/CMV-IE/HIV-TAR chimeric long terminal repeats
|
|
US5573925A
(en)
|
1994-11-28 |
1996-11-12 |
The Wistar Institute Of Anatomy And Biology |
P53 proteins with altered tetramerization domains
|
|
US5721340A
(en)
|
1994-11-28 |
1998-02-24 |
The Wistar Institute Of Anatomy & Biology |
p53 proteins with altered tetramerization domains
|
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
|
JP3770333B2
(ja)
|
1995-03-15 |
2006-04-26 |
大日本住友製薬株式会社 |
組換えdnaウイルスおよびその製造方法
|
|
US6110456A
(en)
|
1995-06-07 |
2000-08-29 |
Yale University |
Oral delivery or adeno-associated viral vectors
|
|
JPH11510389A
(ja)
|
1995-07-31 |
1999-09-14 |
アメリカ合衆国 |
細胞タンパク質の機能を不活性化するためのタンパク質−タンパク質相互作用表面の拡張
|
|
US6013516A
(en)
|
1995-10-06 |
2000-01-11 |
The Salk Institute For Biological Studies |
Vector and method of use for nucleic acid delivery to non-dividing cells
|
|
WO1997023631A2
(fr)
*
|
1995-12-22 |
1997-07-03 |
Somatogen, Inc. |
Globines incluant des domaines de liaison
|
|
CA2239303A1
(fr)
*
|
1995-12-22 |
1997-07-03 |
Somatogen, Inc. |
Globines incluant des domaines de liaison
|
|
US5861397A
(en)
|
1996-10-03 |
1999-01-19 |
Vical Incorporated |
Piperazine based cytofectins
|
|
US6096291A
(en)
|
1996-12-27 |
2000-08-01 |
Biovector Therapeutics, S.A. |
Mucosal administration of substances to mammals
|
|
EP1039931B1
(fr)
|
1997-12-01 |
2005-04-27 |
Fang Fang |
Anticorps de recombinaison multivalents destines au traitement d'infections dues au rhinovirus humain (hrv)
|
|
DE19815331A1
(de)
*
|
1998-04-06 |
1999-10-14 |
Karlsruhe Forschzent |
Transkriptionsfaktoren und deren Verwendung
|
|
US20020165153A1
(en)
|
1998-04-06 |
2002-11-07 |
Peter Angel |
Transcription factors and their use
|
|
US5965712A
(en)
|
1998-06-19 |
1999-10-12 |
Virginia Commonwealth University |
LZ-CD23 chimera for inhibition of IgE-mediated allergic disease
|
|
ES2265693T3
(es)
*
|
1998-10-16 |
2007-02-16 |
Biogen Idec Ma Inc. |
Proteinas de fusion con interferon-beta y usos.
|
|
US20030035798A1
(en)
|
2000-08-16 |
2003-02-20 |
Fang Fang |
Humanized antibodies
|
|
ATE477273T1
(de)
*
|
1998-12-01 |
2010-08-15 |
Facet Biotech Corp |
Humanisierte antikoerper gegen gamma-interferon
|
|
WO2001019842A1
(fr)
|
1999-09-17 |
2001-03-22 |
Genzyme Transgenics Corporation |
Proteine de fusion optimisee par des sous-unites
|
|
CN101643512A
(zh)
|
2000-04-28 |
2010-02-10 |
行星生物技术有限公司 |
预防鼻病毒感染的新型免疫粘附素
|
|
CA2454358A1
(fr)
|
2001-07-19 |
2003-07-31 |
Perlan Therapeutics, Inc. |
Proteines multimeres et methodes de production et d'utilisation de ces proteines
|
|
JP4236000B2
(ja)
|
2003-09-25 |
2009-03-11 |
元気株式会社 |
3次元画像処理装置、3次元画像処理方法及びプログラム
|