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WO2003048766A3 - Colorimetric artemisinin and artemisinin derivatives assay and assay kit - Google Patents

Colorimetric artemisinin and artemisinin derivatives assay and assay kit Download PDF

Info

Publication number
WO2003048766A3
WO2003048766A3 PCT/US2002/037987 US0237987W WO03048766A3 WO 2003048766 A3 WO2003048766 A3 WO 2003048766A3 US 0237987 W US0237987 W US 0237987W WO 03048766 A3 WO03048766 A3 WO 03048766A3
Authority
WO
WIPO (PCT)
Prior art keywords
artemisinin
assay
colorimetric
derivatives
kit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2002/037987
Other languages
French (fr)
Other versions
WO2003048766A2 (en
Inventor
Michael D Green
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centers of Disease Control and Prevention CDC
US Department of Health and Human Services
Original Assignee
Centers of Disease Control and Prevention CDC
US Department of Health and Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centers of Disease Control and Prevention CDC, US Department of Health and Human Services filed Critical Centers of Disease Control and Prevention CDC
Priority to AU2002365753A priority Critical patent/AU2002365753A1/en
Publication of WO2003048766A2 publication Critical patent/WO2003048766A2/en
Publication of WO2003048766A3 publication Critical patent/WO2003048766A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)

Abstract

Disclosed are methods and kits that enable visual detection of the presence of atemisinin and/or an artemisinin derivative in a sample. The method involves a colorimetric assay that includes contacting the sample with a least one reagent to form an analyte and observing the analyte for a color change that occurs in the presence of artemisinin and/or artemisinin derivative, but not in the absence of artemisinin and/or an artemisinin derivative.
PCT/US2002/037987 2001-11-29 2002-11-26 Colorimetric artemisinin and artemisinin derivatives assay and assay kit Ceased WO2003048766A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002365753A AU2002365753A1 (en) 2001-11-29 2002-11-26 Colorimetric artemisinin and artemisinin derivatives assay and assay kit

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33438701P 2001-11-29 2001-11-29
US60/334,387 2001-11-29

Publications (2)

Publication Number Publication Date
WO2003048766A2 WO2003048766A2 (en) 2003-06-12
WO2003048766A3 true WO2003048766A3 (en) 2004-02-12

Family

ID=23306964

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/037987 Ceased WO2003048766A2 (en) 2001-11-29 2002-11-26 Colorimetric artemisinin and artemisinin derivatives assay and assay kit

Country Status (2)

Country Link
AU (1) AU2002365753A1 (en)
WO (1) WO2003048766A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0600031D0 (en) * 2006-01-03 2006-02-08 London School Hygiene & Tropical Medicine Assay
CN100445726C (en) * 2006-08-09 2008-12-24 重庆医科大学 A kind of determination method of artemisinin content in Artemisia annua
WO2009061808A2 (en) * 2007-11-05 2009-05-14 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, Colorimetric test for antimalarial artemesin derivatives
CN102053122A (en) * 2009-11-11 2011-05-11 重庆医药工业研究院有限责任公司 Method for measuring related substances of compound artesunate amodiaquine hydrochloride granules
CN102890087A (en) * 2012-11-13 2013-01-23 宁夏医科大学 Method for measuring artemisinin content in traditional Chinese medicinal materials such as Artemisia annua and samples containing artemisinin components
CN103808827A (en) * 2014-03-01 2014-05-21 张家港威胜生物医药有限公司 High performance liquid chromatography method for measuring content of artesunate
CN103884805A (en) * 2014-03-27 2014-06-25 张家港威胜生物医药有限公司 High performance liquid chromatography method for determining content of artesunate tablets
US10429400B2 (en) * 2014-05-08 2019-10-01 South Dakota Board Of Regents Chemical assay to verify the quantity and quality of sesquiterpene lactone derivatives
CN110007033A (en) * 2019-05-14 2019-07-12 重庆市畜牧科学院 Method for simultaneous detection of artemisinin, dihydroartemisinin and artesunate

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4771005A (en) * 1983-06-27 1988-09-13 Erez Forensic Technology Ltd. Reagents, test kits and methods for the detection of cannabinoids
US4892833A (en) * 1982-07-07 1990-01-09 Boehringer Mannheim Gmbh Process and a reagent kit for the determination of direct and total filirubin

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4892833A (en) * 1982-07-07 1990-01-09 Boehringer Mannheim Gmbh Process and a reagent kit for the determination of direct and total filirubin
US4771005A (en) * 1983-06-27 1988-09-13 Erez Forensic Technology Ltd. Reagents, test kits and methods for the detection of cannabinoids

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
DATABASE MEDLINE [online] US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US; 27 November 1992 (1992-11-27), THOMAS C G ET AL: "Selective determination, in plasma, of artemether and its major metabolite, dihydroartemisinin, by high-performance liquid chromatography with ultraviolet detection.", XP002249776, Database accession no. NLM1484087 *
DATABASE MEDLINE [online] US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US; October 1965 (1965-10-01), SHENG S G ET AL: "[Colorimetric determination of antimalarial drugs and their tablets by means of ammonium reineckate]", XP002249777, Database accession no. NLM5899052 *
GREEN M D ET AL: "A colorimetric field method to assess the authenticity of drugs sold as the antimalarial artesunate.", JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. ENGLAND DEC 2000, vol. 24, no. 1, December 2000 (2000-12-01), pages 65 - 70, XP002249775, ISSN: 0731-7085 *
GREEN M D ET AL: "Authentication of artemether, artesunate and dihydroartemisinin antimalarial tablets using a simple colorimetric method.", TROPICAL MEDICINE & INTERNATIONAL HEALTH: TM & IH. ENGLAND DEC 2001, vol. 6, no. 12, December 2001 (2001-12-01), pages 980 - 982, XP002249774, ISSN: 1360-2276 *
JOURNAL OF CHROMATOGRAPHY. NETHERLANDS 27 NOV 1992, vol. 583, no. 1, 27 November 1992 (1992-11-27), pages 131 - 136, ISSN: 0021-9673 *
YAO XUE XUE BAO = ACTA PHARMACEUTICA SINICA. CHINA OCT 1965, vol. 12, no. 10, October 1965 (1965-10-01), pages 662 - 666, ISSN: 0513-4870 *

Also Published As

Publication number Publication date
AU2002365753A1 (en) 2003-06-17
WO2003048766A2 (en) 2003-06-12
AU2002365753A8 (en) 2003-06-17

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