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WO2003043564A1 - Dispositif de transfert - Google Patents

Dispositif de transfert Download PDF

Info

Publication number
WO2003043564A1
WO2003043564A1 PCT/IB2002/004837 IB0204837W WO03043564A1 WO 2003043564 A1 WO2003043564 A1 WO 2003043564A1 IB 0204837 W IB0204837 W IB 0204837W WO 03043564 A1 WO03043564 A1 WO 03043564A1
Authority
WO
WIPO (PCT)
Prior art keywords
passage
casing
transit
liquid
gas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2002/004837
Other languages
English (en)
Inventor
Mauro Mantovani
Massimo Soffritti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aries Srl
Original Assignee
Aries Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aries Srl filed Critical Aries Srl
Priority to AU2002366012A priority Critical patent/AU2002366012A1/en
Priority to EP20020803490 priority patent/EP1455729A1/fr
Publication of WO2003043564A1 publication Critical patent/WO2003043564A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/162—Needle sets, i.e. connections by puncture between reservoir and tube ; Connections between reservoir and tube
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D29/00—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor
    • B01D29/01—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with flat filtering elements
    • B01D29/05—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with flat filtering elements supported
    • B01D29/055—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with flat filtering elements supported ring shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D29/00—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor
    • B01D29/88—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor having feed or discharge devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D46/00—Filters or filtering processes specially modified for separating dispersed particles from gases or vapours
    • B01D46/0002—Casings; Housings; Frame constructions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D46/00—Filters or filtering processes specially modified for separating dispersed particles from gases or vapours
    • B01D46/10—Particle separators, e.g. dust precipitators, using filter plates, sheets or pads having plane surfaces
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/201—Piercing means having one piercing end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2068—Venting means
    • A61J1/2075—Venting means for external venting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2079—Filtering means
    • A61J1/2082—Filtering means for gas filtration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2079—Filtering means
    • A61J1/2086—Filtering means for fluid filtration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/162—Needle sets, i.e. connections by puncture between reservoir and tube ; Connections between reservoir and tube
    • A61M2005/1623—Details of air intake
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/165—Filtering accessories, e.g. blood filters, filters for infusion liquids

Definitions

  • This invention concerns an apparatus for transferring pharmaceuticals the preparation of which requires the dilution of a powder preparation.
  • pharmaceuticals in particular antibiotic and chemotherapeutic pharmaceuticals
  • lyophilised pharmaceuticals or pharmaceuticals in powder form are diluted in the prior art by means of a diluting liquid and the preparation thereby obtained is subsequently transferred into suitable containers, for example bags, from which said preparation is drawn during administration .
  • Said preparation is made up by injecting the diluting liquid by means of a syringe into a bottle containing the lyophilised pharmaceutical or pharmaceutical in powder form, gently shaking the bottle to enable perfect dilution and subsequently drawing by means of the syringe the preparation thereby obtained to transfer it into one of the aforementioned containers .
  • the pharmaceuticals must be handled in secure conditions to prevent accidental contact with the operator's skin or eyes.
  • Said body furthermore comprises an intermediate portion that connects the top portion and the bottom portion, provided with a central opening that constitutes a passage for the transfer of the fluid between the syringe and the bottle.
  • the intermediate portion furthermore comprises a tip that is internally provided with a hollow conduit that extends downwards from the bottom of the central opening for a distance that is sufficient to enable the bottom end of the tip to perforate a closing seal, which shuts the bottle that is associated with the bottom portion of the device and to penetrate inside the latter.
  • the hollow conduit enables air to enter inside the bottle in such a way that the pressure inside the bottle is the same as the atmospheric pressure outside the bottle.
  • the device may furthermore comprise a filtering element associated with the opening that connects the bottle and the syringe, said filtering element being suitable for retaining pharmaceutical particles with a large diameter, which may obstruct the syringe.
  • DE 3820204 discloses a device for filtering and transferring a fluid, in particular for medical use, into or from a container.
  • the device comprises a support plate, formed through the juxtaposition of two portions, between which a first filter for liquid substances and a second filter for gaseous substances are placed.
  • the two portions are made in such a way as to delimit two filter chambers, which do not communicate with each other, one for the first filter, the other for the second filter.
  • One of the two opposite faces of the plate is provided with a perforating tip that is arranged axially, in the thickness of which a first conduit runs that communicates with the chamber provided with the first filter and a second conduit runs communicating with the chamber accommodating the second filter.
  • a fitting conduit is inserted to receive an aspirating instrument, for example a syringe, and a vent conduit is inserted for the passage of gas, both conduits being eccentrically arranged in relation to a longitudinal axis of the device that passes through the tip.
  • the fitting conduit communicates with the filtering chamber of the liquids
  • the vent conduit communicates with the filtering chamber of the gases.
  • the latter are provided with channels radially arranged. In the portion of the plate comprising the perforating tip the radially arranged channels converge towards the internal discharge orifices of the first or of the second conduit. In the opposite portion of the plate, the radially arranged channels converge towards the internal discharge orifices of the fitting conduit or of the vent conduit .
  • any toxic gaseous substances rising from the reconstituted pharmaceutical pass into the channel for the gases of the tip and then into the gas- filtering chamber. In this way, the harmful components of the gases are retained by the filter.
  • the latter is aspirated by the bottle, always by means of a syringe, and passing through the filtering-liquid chamber it is deprived of any residual solid particles.
  • the vent conduit enables the atmospheric air to enter the bottle, thereby enabling the latter to be emptied.
  • DE 3820204 provides a substantially voluminous vent conduit that is therefore cumbersome during handling of the device by the operator.
  • the fitting conduit is positioned in a position that is shifted in relation to a longitudinal axis of the tip, which is located in a central position. This causes precarious balance when in use, for example when a syringe is connected to the device after the tip of the latter has been inserted into a stopper of the container, or during aspiration and/or delivery of the liquid by the syringe. This precarious equilibrium may cause accidental overturning of the device and consequent spreading of harmful substances in the environment .
  • Fig. 9 is an enlarged and interrupted detail of a central zone of Fig. 4;
  • Fig. 10 is an enlarged and interrupted detail of an end zone of Fig. 7;
  • Fig. 11 is an enlarged and interrupted detail of a central zone of Fig. 7;
  • Fig. 12 is a longitudinal section of a further version of the apparatus disclosed in the invention.
  • Fig. 13 and Fig. 14 are enlarged and interrupted details of
  • Fig. 1 shows an apparatus 1 for diluting pharmaceuticals comprising a first portion 2 provided with a fitting 5, such as a LUER-LOCK, arranged for being coupled with a syringe (not shown) and a further portion 3 provided with a tip 4 suitable for being inserted inside a container (not shown) wherein a pharmaceutical that is to be diluted is contained.
  • the apparatus 1 furthermore comprises an intermediate body 8, with a circular section, inside which a filtering means 6 is housed that is arranged to filter the preparation obtained by dilution of the pharmaceutical before this is transferred, by means of said syringe, to inside a collection container that is not shown.
  • the apparatus 1 furthermore comprises a gas-filtering means 7, which is also suitable for being positioned inside the intermediate body 8, arranged to filter any gases generated inside the container by chemical reactions that occur during dilution of the pharmaceutical before said gases are delivered into the surrounding environment.
  • a gas-filtering means 7 which is also suitable for being positioned inside the intermediate body 8, arranged to filter any gases generated inside the container by chemical reactions that occur during dilution of the pharmaceutical before said gases are delivered into the surrounding environment.
  • the first portion 2 and the further portion 3 may be made out of plastic that resists diluting solutions and is also compatible with pharmaceuticals, particularly with pharmaceuticals containing lipids.
  • said plastic is a transparent plastic.
  • Said plastic is preferably polycarbonate.
  • the gas-filtering means 7 can be made from a membrane in polyethersulphone.
  • gas-filtering means 7 is suitable for being subjected to sterilisation treatment using ethylene oxide.
  • the polyethersulphone membrane is not damaged by ultrasonic sealing by means of which the first part 2 is fixed to the further part 3.
  • the gas-filtering means comprising a polyethersulphone membrane is furthermore compatible with USP class VI.
  • Figs. 2 to 11 show the first portion 2 and the further portion 3 of the apparatus 1, wherein a casing means 9 are identified that is suitable for receiving the filtering means 6 and the gas-filtering means 7.
  • the first casing means 9a furthermore comprises a second wall means 15 and a third wall means 16, which also protrude from the first surface 13, arranged so as to peripherally delimit the first transit means 10a and the first passage means 11a, respectively.
  • the filtering means 6 and the gas-filtering means 7 are located inside the second casing means 9b, respectively in the second transit means 10b and in the second passage means lib. Subsequently, the first portion 2 is associated with the further portion 3 in such a way that the first surface 13 and the further surface 14 face one another.
  • the first wall means 12 is received inside the annular groove 21 and the first jutting element 19 engages the first groove 17 in such a way that, following the junction of the first casing means 9a and of the second casing means 9b, the casing means 9 are defined.
  • the second jutting element 20 is received in the second groove 18 in such a way as to identify in the casing means 9 the transit means 10 and the passage means 11.
  • the second casing means 9b is provided with a support means 22 arranged to support the filtering means 6 and the gas-filtering means 7, so as to maintain them at a set distance from a face that delimits the second casing means 9b at the bottom.
  • the support means 22 comprises a step 23 extending along the first jutting element 19 and arranged to receive end zones of the filtering means 6 and of the gas-filtering means 7, which rest on said first jutting element 19.
  • third transit means 24 are made out that are provided with a first orifice 25 arranged to put into a container a liquid arranged to dilute a pharmaceutical, or to draw the diluted pharmaceutical from the above-mentioned container.
  • the first orifice 25 is configured in such a way as to longitudinally occupy a set extension of the cone-shaped end 4a of the tip 4. In this way, in one work configuration wherein the tip 4 is arranged vertically in such a way that the cone-shaped end 4a is positioned higher than the body 8, it is possible to substantially draw the entire contents of the container associated with it thereby minimising in this way consumption of the pharmaceutical.
  • the third transit means 24 furthermore comprises a second orifice 26 opening inside the transit means 10.
  • a third passage means 27 is furthermore made out that is provided with a further first orifice 28, arranged at the cone-shaped end 4a, and a further second orifice 29 opening inside the passage means 11.
  • the second transit means 10a is provided with a rib means 30 that collaborates with the step 23 to support the gas-filtering means 6.
  • the rib means 30 furthermore defines the channels 31 that direct the liquid towards the second orifice 26. As Figs, from 2 to 4 show, the first portion 2 is crossed by a hole 32 arranged to make the fitting 5 communicate with the transit means 10.
  • a diluting liquid can be placed inside a container containing a pharmaceutical in powder form, or a diluted pharmaceutical can be drawn from the container, said diluting liquid and diluted pharmaceuticals being made to pass through the filtering means 6.
  • the first passage means 11a is provided with a plurality of opening means 34, made in the form of orifices and arranged to allow any gases containing toxic substances, produced after the dilution of the pharmaceutical, to be released into the outside environment after passing through the gas-filtering means 7.
  • the opening means 34 furthermore enables appropriately filtered atmospheric air to penetrate the container containing the diluted pharmaceutical when the latter is drawn by a syringe, thereby enabling the container to be emptied.
  • the opening means 34 is made in the entire extension of the first passage means 11a, to exploit the entire active surface of the gas-filtering means 7.
  • Figs. 12 and 13 show a possible embodiment of the invention wherein the tip 4 is replaced by a support body 40 made into a roughly trunk-conical shape that is elongated and hollow inside.
  • the support body 40 is fixed to the further portion 3 near a central region of the latter, and is arranged to accommodate a perforating cannula 41, for example made of steel, provided internally with a conduit 57 and kept in their seat by gluing with a suitable adhesive means.
  • the perforating cannula 41 accommodated for about two thirds of its own length inside the support body 40, comprises in its external third a terminal orifice 42.
  • the terminal orifice 42 is arranged in a noticeably oblique manner in relation to a longitudinal axis X of the cannula 41. It is thus possible to efficiently draw from a container even small residual quantities of pharmaceutical.
  • the cannula 41 may be of the so-called teaspoon' type, i.e. it may be curved near the terminal orifice 42. During use of the device this significantly reduces phenomena of 'coring', i.e. removal of fragments of stopper when said stopper is bored to access a container, which is not shown.
  • the end of the perforating cannula 41 opposite the end bearing the terminal orifice 42 comprises a joint portion 44.
  • the support body 40 accommodates a jacket 45 internally, having an open end to receive the perforating cannula 41 and the opposite end closed by a second jutting element 46 arranged to engage in the second channel 18 of the first portion 2.
  • the jacket 45 is provided internally with an abutting edge 47, arranged as a ring at a certain distance from the second jutting element 46, and such as to accommodate the joint portion 44. Between the joint portion 44 and the further jutting element 46 there is thus comprised a bottom portion 49 of the jacket 45.
  • the part of the bottom portion 49 pointing towards the transit means 10 defines a transit orifice 48, communicating by means of a transit conduit 52 having an arched longitudinal section, with the transit means 10.
  • the conduit 57, the bottom portion 49 and the transit conduit 52 constitute a structure that is functionally analogous with the third transit means 24.
  • the support body 40 for a tract that is the same as about half its length, accommodates four ribs 50, roughly shaped in the form of a rectangular trapezium and arranged in such a way that any two are at right angles to each other.
  • One of the ribs 50 i.e. the one nearest to the passage means 11, is hollow and delimits a passage chamber 54, provided with two lateral walls that are not shown, fixed to an intermediate wall 58.
  • the jacket 45 partially separates the passage chamber 54 from the adjacent conduit 57, inasmuch as it is interrupted before reaching the zone near which the intermediate wall 58 fits onto the support body 40.

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Regulation And Control Of Combustion (AREA)

Abstract

L'invention concerne un appareil permettant de diluer et de transférer un dispositif liquide comprenant des dispositifs de transit (10, 24, 49, 52, 57) reliés audit dispositif liquide afin de distribuer au et/ou extraire du contenant ledit dispositif liquide, des dispositifs de passage (11, 27, 54, 56) disposés de manière à permettre le passage de gaz entre ledit contenant et un environnement extérieur, des dispositifs de logement (2, 3, 8, 9) contenant un dispositif de filtrage de gaz (7) conçu de manière à filtrer ledit gaz et doté d'un dispositif d'ouverture (34) destiné à ce gaz, et caractérisé par le fait que ledit dispositif d'ouverture (34) est adapté de manière à ne pas faire saillie depuis le dispositif de logement en question (2, 3, 8, 9).
PCT/IB2002/004837 2001-11-22 2002-11-20 Dispositif de transfert Ceased WO2003043564A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2002366012A AU2002366012A1 (en) 2001-11-22 2002-11-20 Transferring device
EP20020803490 EP1455729A1 (fr) 2001-11-22 2002-11-20 Dispositif de transfert

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMO2001A000226 2001-11-22
IT2001MO000226A ITMO20010226A1 (it) 2001-11-22 2001-11-22 Apparato

Publications (1)

Publication Number Publication Date
WO2003043564A1 true WO2003043564A1 (fr) 2003-05-30

Family

ID=11450912

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2002/004837 Ceased WO2003043564A1 (fr) 2001-11-22 2002-11-20 Dispositif de transfert

Country Status (4)

Country Link
EP (1) EP1455729A1 (fr)
AU (1) AU2002366012A1 (fr)
IT (1) ITMO20010226A1 (fr)
WO (1) WO2003043564A1 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1797919A1 (fr) * 2005-12-16 2007-06-20 Bracco Research S.A. Dispositif pour le transfert de liquides pour récipient de distribution de médicaments
CN102762182A (zh) * 2010-02-22 2012-10-31 弗雷泽纽斯卡比德国有限公司 用于将液体输送到容器中或从容器中提取出的装置
EP2811964A4 (fr) * 2012-02-07 2015-09-23 Yukon Medical Llc Dispositif de transvasement équipé d'un filtre pour fluide
WO2016120163A1 (fr) * 2015-01-26 2016-08-04 Bayer Pharma Aktiengesellschaft Module d'aiguille creuse

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4294594A (en) * 1979-10-02 1981-10-13 United States Surgical Corporation Self-contained filter assembly for removing air, particles and bacteria from a solution
US4743243A (en) * 1984-01-03 1988-05-10 Vaillancourt Vincent L Needle with vent filter assembly
DE3820204A1 (de) 1988-06-14 1989-12-21 Axel Von Brand Vorrichtung zum gefilterten zufuehren bzw. entnehmen von fluessigkeit in bzw. aus einem behaeltnis, insbesondere einer flasche
WO2000007539A1 (fr) 1998-08-06 2000-02-17 Baxter International Inc. Dispositif servant a reconstituer des medicaments afin de les injecter
US6139534A (en) * 2000-01-24 2000-10-31 Bracco Diagnostics, Inc. Vial access adapter
WO2001010486A1 (fr) * 1999-08-04 2001-02-15 Caremed Medical Produkte Ag Dispositif de prelevement destine au prelevement sterile d'un liquide dans un recipient
EP1192927A2 (fr) * 2000-09-30 2002-04-03 B. Braun Melsungen Ag Pointe pour prélèvement
WO2002032372A1 (fr) * 2000-10-17 2002-04-25 Biodome Dispositif de connexion entre un recipient et un contenant et ensemble pret a l'emploi comprenant un tel dispositif
WO2002076374A1 (fr) * 2001-03-27 2002-10-03 Eli Lilly And Company Trousse incluant une aiguille de seringue a injection laterale pour preparer un medicament dans une cartouche de stylo injecteur

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4294594A (en) * 1979-10-02 1981-10-13 United States Surgical Corporation Self-contained filter assembly for removing air, particles and bacteria from a solution
US4743243A (en) * 1984-01-03 1988-05-10 Vaillancourt Vincent L Needle with vent filter assembly
DE3820204A1 (de) 1988-06-14 1989-12-21 Axel Von Brand Vorrichtung zum gefilterten zufuehren bzw. entnehmen von fluessigkeit in bzw. aus einem behaeltnis, insbesondere einer flasche
WO2000007539A1 (fr) 1998-08-06 2000-02-17 Baxter International Inc. Dispositif servant a reconstituer des medicaments afin de les injecter
WO2001010486A1 (fr) * 1999-08-04 2001-02-15 Caremed Medical Produkte Ag Dispositif de prelevement destine au prelevement sterile d'un liquide dans un recipient
US6139534A (en) * 2000-01-24 2000-10-31 Bracco Diagnostics, Inc. Vial access adapter
EP1192927A2 (fr) * 2000-09-30 2002-04-03 B. Braun Melsungen Ag Pointe pour prélèvement
WO2002032372A1 (fr) * 2000-10-17 2002-04-25 Biodome Dispositif de connexion entre un recipient et un contenant et ensemble pret a l'emploi comprenant un tel dispositif
WO2002076374A1 (fr) * 2001-03-27 2002-10-03 Eli Lilly And Company Trousse incluant une aiguille de seringue a injection laterale pour preparer un medicament dans une cartouche de stylo injecteur

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1797919A1 (fr) * 2005-12-16 2007-06-20 Bracco Research S.A. Dispositif pour le transfert de liquides pour récipient de distribution de médicaments
WO2007068633A1 (fr) * 2005-12-16 2007-06-21 Bracco Research Sa Appareil de transfert de liquides pour contenants distributeurs médicaux
AU2006326148B2 (en) * 2005-12-16 2013-01-17 Bracco Suisse S.A. Liquid transfer device for medical dispensing containers
US9238103B2 (en) 2005-12-16 2016-01-19 Bracco Suisse S.A. Liquid transfer device for medical dispensing containers
CN102762182A (zh) * 2010-02-22 2012-10-31 弗雷泽纽斯卡比德国有限公司 用于将液体输送到容器中或从容器中提取出的装置
EP2811964A4 (fr) * 2012-02-07 2015-09-23 Yukon Medical Llc Dispositif de transvasement équipé d'un filtre pour fluide
US9585812B2 (en) 2012-02-07 2017-03-07 Yukon Medical, Llc Transfer device with fluid filter
WO2016120163A1 (fr) * 2015-01-26 2016-08-04 Bayer Pharma Aktiengesellschaft Module d'aiguille creuse

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AU2002366012A1 (en) 2003-06-10
EP1455729A1 (fr) 2004-09-15
ITMO20010226A1 (it) 2003-05-22
ITMO20010226A0 (it) 2001-11-22

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