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WO2002100378A3 - Process for the preparation of a particulate material - Google Patents

Process for the preparation of a particulate material Download PDF

Info

Publication number
WO2002100378A3
WO2002100378A3 PCT/GB2002/002423 GB0202423W WO02100378A3 WO 2002100378 A3 WO2002100378 A3 WO 2002100378A3 GB 0202423 W GB0202423 W GB 0202423W WO 02100378 A3 WO02100378 A3 WO 02100378A3
Authority
WO
WIPO (PCT)
Prior art keywords
particulate material
preparation
drying
volatilising
laser
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB2002/002423
Other languages
French (fr)
Other versions
WO2002100378A2 (en
Inventor
Philip Braithwaite
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Innovata Ltd
Original Assignee
ML Laboratories PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ML Laboratories PLC filed Critical ML Laboratories PLC
Priority to AU2002302767A priority Critical patent/AU2002302767A1/en
Publication of WO2002100378A2 publication Critical patent/WO2002100378A2/en
Publication of WO2002100378A3 publication Critical patent/WO2002100378A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D1/00—Evaporating
    • B01D1/0011—Heating features
    • B01D1/0029—Use of radiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D1/00—Evaporating
    • B01D1/16—Evaporating by spraying
    • B01D1/18—Evaporating by spraying to obtain dry solids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Preparation (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

There is described a process for the preparation of a particulate material which comprises atomising and drying a solution of the material characterised in that the drying is achieved by volatilising the solvent with a laser. There is also described a particulate material produced by a method of the invention and a method of treatment related thereto.
PCT/GB2002/002423 2001-06-09 2002-06-10 Process for the preparation of a particulate material Ceased WO2002100378A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002302767A AU2002302767A1 (en) 2001-06-09 2002-06-10 Process for the preparation of a particulate material

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0114033A GB0114033D0 (en) 2001-06-09 2001-06-09 Process
GB0114033.4 2001-06-09

Publications (2)

Publication Number Publication Date
WO2002100378A2 WO2002100378A2 (en) 2002-12-19
WO2002100378A3 true WO2002100378A3 (en) 2003-04-10

Family

ID=9916229

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2002/002423 Ceased WO2002100378A2 (en) 2001-06-09 2002-06-10 Process for the preparation of a particulate material

Country Status (3)

Country Link
AU (1) AU2002302767A1 (en)
GB (1) GB0114033D0 (en)
WO (1) WO2002100378A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070023035A1 (en) * 2005-07-29 2007-02-01 Kane Kevin M Method for processing drugs
DK1957539T3 (en) 2005-12-08 2013-05-06 Medarex Inc HUMAN MONOCLONAL ANTIBODIES FOR PROTEINTYROSINKINASE 7 (PTK7) AND THEIR USE
EP2001796A2 (en) * 2006-03-03 2008-12-17 Battelle Memorial Institute Method and apparatus for high mass concentration nano particle generation
WO2012047620A1 (en) * 2010-09-28 2012-04-12 Goji Ltd. Systems and methods for solution concentration using electromagnetic energy

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0360340A1 (en) * 1988-09-19 1990-03-28 Akzo N.V. Composition for nasal administration containing a peptide
FR2677558A1 (en) * 1991-06-14 1992-12-18 Commissariat Energie Atomique Process and device for the manufacture of ultrafine inorganic powders by aerosol-laser coupling
US5458135A (en) * 1991-07-02 1995-10-17 Inhale Therapeutic Systems Method and device for delivering aerosolized medicaments
WO1996019197A1 (en) * 1994-12-22 1996-06-27 Astra Aktiebolag Aerosol formulations of peptides and proteins
US5658878A (en) * 1993-06-24 1997-08-19 Ab Astra Therapeutic preparation for inhalation
US5738087A (en) * 1995-09-21 1998-04-14 King; Russell W. Aerosol medication delivery system
WO2000061178A1 (en) * 1999-04-13 2000-10-19 Inhale Therapeutics Systems, Inc. Pulmonary administration of dry powder formulations for treating infertility
WO2000062819A1 (en) * 1999-04-21 2000-10-26 1355540 Ontario Inc. Formulations for detecting asthma
US6138673A (en) * 1995-06-29 2000-10-31 Fisons Limited Inhalation device and method
WO2001054742A1 (en) * 2000-01-25 2001-08-02 Aeropharm Technology, Inc. A medicinal aerosol formulation

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0360340A1 (en) * 1988-09-19 1990-03-28 Akzo N.V. Composition for nasal administration containing a peptide
FR2677558A1 (en) * 1991-06-14 1992-12-18 Commissariat Energie Atomique Process and device for the manufacture of ultrafine inorganic powders by aerosol-laser coupling
US5458135A (en) * 1991-07-02 1995-10-17 Inhale Therapeutic Systems Method and device for delivering aerosolized medicaments
US5658878A (en) * 1993-06-24 1997-08-19 Ab Astra Therapeutic preparation for inhalation
WO1996019197A1 (en) * 1994-12-22 1996-06-27 Astra Aktiebolag Aerosol formulations of peptides and proteins
US6138673A (en) * 1995-06-29 2000-10-31 Fisons Limited Inhalation device and method
US5738087A (en) * 1995-09-21 1998-04-14 King; Russell W. Aerosol medication delivery system
WO2000061178A1 (en) * 1999-04-13 2000-10-19 Inhale Therapeutics Systems, Inc. Pulmonary administration of dry powder formulations for treating infertility
WO2000062819A1 (en) * 1999-04-21 2000-10-26 1355540 Ontario Inc. Formulations for detecting asthma
WO2001054742A1 (en) * 2000-01-25 2001-08-02 Aeropharm Technology, Inc. A medicinal aerosol formulation

Also Published As

Publication number Publication date
AU2002302767A1 (en) 2002-12-23
WO2002100378A2 (en) 2002-12-19
GB0114033D0 (en) 2001-08-01

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