[go: up one dir, main page]

WO2002036781A3 - Regulation of human glutathione-s-transferase - Google Patents

Regulation of human glutathione-s-transferase Download PDF

Info

Publication number
WO2002036781A3
WO2002036781A3 PCT/EP2001/012475 EP0112475W WO0236781A3 WO 2002036781 A3 WO2002036781 A3 WO 2002036781A3 EP 0112475 W EP0112475 W EP 0112475W WO 0236781 A3 WO0236781 A3 WO 0236781A3
Authority
WO
WIPO (PCT)
Prior art keywords
transferase
human glutathione
regulation
reagents
glutathione
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2001/012475
Other languages
French (fr)
Other versions
WO2002036781A2 (en
Inventor
Rainer H Koehler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Priority to AU2002220668A priority Critical patent/AU2002220668A1/en
Publication of WO2002036781A2 publication Critical patent/WO2002036781A2/en
Publication of WO2002036781A3 publication Critical patent/WO2002036781A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
    • C12N9/1088—Glutathione transferase (2.5.1.18)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Reagents which regulate human glutathione-S-transferase and reagents which bind to human glutathione-S-transferase gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, cancer and CNS disorders.
PCT/EP2001/012475 2000-10-31 2001-10-29 Regulation of human glutathione-s-transferase Ceased WO2002036781A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002220668A AU2002220668A1 (en) 2000-10-31 2001-10-29 Regulation of human glutathione-s-transferase

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US24421800P 2000-10-31 2000-10-31
US60/244,218 2000-10-31
US32522001P 2001-09-28 2001-09-28
US60/325,220 2001-09-28

Publications (2)

Publication Number Publication Date
WO2002036781A2 WO2002036781A2 (en) 2002-05-10
WO2002036781A3 true WO2002036781A3 (en) 2003-02-06

Family

ID=26936399

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/012475 Ceased WO2002036781A2 (en) 2000-10-31 2001-10-29 Regulation of human glutathione-s-transferase

Country Status (2)

Country Link
AU (1) AU2002220668A1 (en)
WO (1) WO2002036781A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070154963A1 (en) * 2005-12-30 2007-07-05 Danying Cai Method to determine whether a compound is a cellular GSTpi inhibitor

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0328939A2 (en) * 1988-02-01 1989-08-23 Teijin Limited Method, reagent, kit and monoclonal antibody for diagnosing cancer in human digestive organs by determining acid glutathione S-transferase
WO1998023758A1 (en) * 1996-11-26 1998-06-04 Incyte Pharmaceuticals, Inc. Human glutathione s-transferase
WO2000058473A2 (en) * 1999-03-31 2000-10-05 Curagen Corporation Nucleic acids including open reading frames encoding polypeptides; 'orfx'
WO2001019860A2 (en) * 1999-09-15 2001-03-22 Incyte Genomics, Inc. Proteins associated with cell differentiation
WO2001042451A2 (en) * 1999-12-08 2001-06-14 Genset FULL-LENGTH HUMAN cDNAs ENCODING POTENTIALLY SECRETED PROTEINS
WO2001055301A2 (en) * 2000-01-31 2001-08-02 Human Genome Sciences, Inc. Nucleic acids, proteins, and antibodies

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0328939A2 (en) * 1988-02-01 1989-08-23 Teijin Limited Method, reagent, kit and monoclonal antibody for diagnosing cancer in human digestive organs by determining acid glutathione S-transferase
WO1998023758A1 (en) * 1996-11-26 1998-06-04 Incyte Pharmaceuticals, Inc. Human glutathione s-transferase
WO2000058473A2 (en) * 1999-03-31 2000-10-05 Curagen Corporation Nucleic acids including open reading frames encoding polypeptides; 'orfx'
WO2001019860A2 (en) * 1999-09-15 2001-03-22 Incyte Genomics, Inc. Proteins associated with cell differentiation
WO2001042451A2 (en) * 1999-12-08 2001-06-14 Genset FULL-LENGTH HUMAN cDNAs ENCODING POTENTIALLY SECRETED PROTEINS
WO2001055301A2 (en) * 2000-01-31 2001-08-02 Human Genome Sciences, Inc. Nucleic acids, proteins, and antibodies

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 17 December 2001 (2001-12-17), ROSEN CA ET AL.: "cDNA encoding novel human enzyme polypeptide #270", XP002212804, Database accession no. AAS41054 *
DATABASE EMBL [online] 18 December 2001 (2001-12-18), ROSEN CA ET AL.: "Novel human enzyme polypeptide #270", XP002212805, Database accession no. AAU23184 *
DATABASE EMBL [online] 30 June 1999 (1999-06-30), NCI-CGAP: "wg81e08.x1 Soares_NSF_F8_9W_OT_PA_P_S1 Homo sapiens cDNA clone IMAGE: 2371526 3' similar to TR:088741 Ganglioside-Induced Diff. assoc. prot.1", XP002212803, Database accession no. AI768135 *
SNYDER M.L. AND MADDISON D.R.: "Molecular Phylogeny of Glutathione-S-Transferases", DNA AND CELL BIOLOGY, MARY ANN LIEBERT INC., vol. 16, no. 11, November 1997 (1997-11-01), pages 1373 - 1384, XP008007988 *

Also Published As

Publication number Publication date
AU2002220668A1 (en) 2002-05-15
WO2002036781A2 (en) 2002-05-10

Similar Documents

Publication Publication Date Title
WO2002036783A3 (en) Regulation of human histone deacetylase
WO2002070675A3 (en) Regulation of human histone acetyltransferase
WO2002030970A3 (en) Human histone deacetylase gene
WO2002072824A3 (en) Human transient receptor potential channel protein.
WO2002002755A3 (en) Regulation of human thimet oligopeptidase-like enzyme
WO2002036781A3 (en) Regulation of human glutathione-s-transferase
WO2002033080A3 (en) Regulation of human netrin binding membrane receptor unc5h-1
WO2002088362A3 (en) Regulation of human prostaglandin-f synthase 1-like protein
WO2002062974A3 (en) Regulation of human elongase hselo1-like protein
WO2002018566A3 (en) Regulation of human l-asparaginase-like enzyme
WO2002057461A3 (en) Regulation of human adam-ts-like zinc metalloprotease
WO2002081705A3 (en) Regulation of human gnat acetyltransferase-like protein
WO2002052020A3 (en) Regulation of human carboxypeptidase a
WO2002062975A3 (en) Regulation of human elongase hselo1-like protein
WO2002022791A3 (en) Regulation of human pyridoxine 5'-phosphate oxidase
WO2002053756A3 (en) Regulation of human glucosamine-6-phosphate deaminase
WO2002033097A3 (en) Regulation of human sulfotransferase
WO2002032938A3 (en) Regulation of human pgc-1-like protein
WO2003052088A3 (en) Regulation of human sialyltransferase
WO2002048323A3 (en) Regulation of human uridine kinase
WO2002051996A3 (en) Regulation of human cyclophilin-like protein
WO2002030969A3 (en) Regulation of human carboxylesterase-like enzyme
WO2002072825A3 (en) Human mrp5-like protein
WO2002033056A3 (en) Regulation of human serine-threonine protein kinase
WO2002006454A3 (en) Regulation of human carboxylesterase-like enzyme

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application
REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP