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WO2002036596A3 - CYCLOALKYL[b][1,4]DIAZEPINO[6,7,1-hi]INDOLES AND DERIVATIVES - Google Patents

CYCLOALKYL[b][1,4]DIAZEPINO[6,7,1-hi]INDOLES AND DERIVATIVES Download PDF

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Publication number
WO2002036596A3
WO2002036596A3 PCT/US2001/046084 US0146084W WO0236596A3 WO 2002036596 A3 WO2002036596 A3 WO 2002036596A3 US 0146084 W US0146084 W US 0146084W WO 0236596 A3 WO0236596 A3 WO 0236596A3
Authority
WO
WIPO (PCT)
Prior art keywords
diazepino
cycloalkyl
disorders
indoles
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/046084
Other languages
French (fr)
Other versions
WO2002036596A2 (en
Inventor
Annmarie Louise Sabb
Robert Lewis Vogel
Gregory Scott Welmaker
Joan Eileen Sabalski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
Wyeth LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth LLC filed Critical Wyeth LLC
Priority to AU2002227170A priority Critical patent/AU2002227170A1/en
Publication of WO2002036596A2 publication Critical patent/WO2002036596A2/en
Publication of WO2002036596A3 publication Critical patent/WO2002036596A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

This invention provides cycloalkyl[1,4] diazepino[6,7,1-hi] indole compounds of the formula (I): or a pharmaceutically acceptable salt thereof, as well as methods and pharmaceutical compositions utilizing them for the treatment or prevention of disorders such as obsessive-compulsive disorder, depression, anxiety, schizophrenia, migraine, sleep disorders, eating disorders, obesity, epilepsy, and spinal cord injury.
PCT/US2001/046084 2000-11-03 2001-11-01 CYCLOALKYL[b][1,4]DIAZEPINO[6,7,1-hi]INDOLES AND DERIVATIVES Ceased WO2002036596A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002227170A AU2002227170A1 (en) 2000-11-03 2001-11-01 Cycloalkyl(b)(1,4)diazepino(6,7,1-hi)indoles and derivatives

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US24559900P 2000-11-03 2000-11-03
US24559800P 2000-11-03 2000-11-03
US24560200P 2000-11-03 2000-11-03
US60/245,598 2000-11-03
US60/245,599 2000-11-03
US60/245,602 2000-11-03

Publications (2)

Publication Number Publication Date
WO2002036596A2 WO2002036596A2 (en) 2002-05-10
WO2002036596A3 true WO2002036596A3 (en) 2002-10-24

Family

ID=27399866

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/046084 Ceased WO2002036596A2 (en) 2000-11-03 2001-11-01 CYCLOALKYL[b][1,4]DIAZEPINO[6,7,1-hi]INDOLES AND DERIVATIVES

Country Status (2)

Country Link
AU (1) AU2002227170A1 (en)
WO (1) WO2002036596A2 (en)

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Citations (1)

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US3914250A (en) * 1974-08-01 1975-10-21 American Home Prod 1,4-Diazepino{8 6,5,4-jk{9 carbazoles

Patent Citations (1)

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US3914250A (en) * 1974-08-01 1975-10-21 American Home Prod 1,4-Diazepino{8 6,5,4-jk{9 carbazoles

Non-Patent Citations (1)

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Title
HÄRTER, H.P. ET AL.: "Schmidt-Reaktion an Tetrahydro-chinolon-Derivaten", CHIMIA, vol. 30, no. 2, 1976, AARAU, CH, pages 50 - 52, XP008006029, ISSN: 0009-4293 *

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AU2002227170A1 (en) 2002-05-15

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