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WO2002030966A3 - Alzheimer's disease-associated proteins - Google Patents

Alzheimer's disease-associated proteins Download PDF

Info

Publication number
WO2002030966A3
WO2002030966A3 PCT/US2001/031076 US0131076W WO0230966A3 WO 2002030966 A3 WO2002030966 A3 WO 2002030966A3 US 0131076 W US0131076 W US 0131076W WO 0230966 A3 WO0230966 A3 WO 0230966A3
Authority
WO
WIPO (PCT)
Prior art keywords
disease
adp
associated proteins
alzheimer
provides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/031076
Other languages
French (fr)
Other versions
WO2002030966A2 (en
Inventor
Yuming Xu
Kavitha Thangavelu
Vicki S Elliott
Y Tom Tang
Henry Yue
Narinder K Walia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Incyte Genomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc filed Critical Incyte Genomics Inc
Priority to US10/398,694 priority Critical patent/US20040102612A1/en
Priority to AU2001296584A priority patent/AU2001296584A1/en
Publication of WO2002030966A2 publication Critical patent/WO2002030966A2/en
Publication of WO2002030966A3 publication Critical patent/WO2002030966A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711Alzheimer's disease; Amyloid plaque core protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention provides human Alzheimer's disease-associated proteins (ADP) and polynucleotides which identify and encode ADP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of ADP.
PCT/US2001/031076 2000-10-06 2001-10-03 Alzheimer's disease-associated proteins Ceased WO2002030966A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US10/398,694 US20040102612A1 (en) 2001-10-03 2001-10-03 Alzheimer's disease-associated proteins
AU2001296584A AU2001296584A1 (en) 2000-10-06 2001-10-03 Alzheimer's disease-associated proteins

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23839100P 2000-10-06 2000-10-06
US60/238,391 2000-10-06

Publications (2)

Publication Number Publication Date
WO2002030966A2 WO2002030966A2 (en) 2002-04-18
WO2002030966A3 true WO2002030966A3 (en) 2003-01-03

Family

ID=22897681

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/031076 Ceased WO2002030966A2 (en) 2000-10-06 2001-10-03 Alzheimer's disease-associated proteins

Country Status (2)

Country Link
AU (1) AU2001296584A1 (en)
WO (1) WO2002030966A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8314221B2 (en) * 2006-09-07 2012-11-20 Laurence Claude Faure Pharmacodiagnostic test targeting oncology and neurodegeneration

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE EM_HUM [online] E.B.I., Hinxton, UK; 2 October 2001 (2001-10-02), HADANO S AND IKEDA J: "Homo sapiens ALS2 mRNA, complete cds, short form", XP002199244, Database accession no. AB053306 *
DATABASE EM-HUM [online] E.B.I., Hinxton, U.K.; 29 September 2000 (2000-09-29), ISOGAI T ET AL.: "Homo sapiens cDNA FLJ12962 fis, clone NT2RP2005694, weakly similar to X-linked retinitis pigmentosa GTPase regulator", XP002199912, Database accession no. AK023024 *
DE LA MONTE SUZANNE M ET AL: "Characterization of the AD7C-NTP cDNA expression in Alzheimer's disease and measurement of a 41-kD protein in cerebrospinal fluid.", JOURNAL OF CLINICAL INVESTIGATION, vol. 100, no. 12, 15 December 1997 (1997-12-15), pages 3093 - 3104, XP002199243, ISSN: 0021-9738 *
HADANO SHINJI ET AL: "A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2.", NATURE GENETICS, vol. 29, no. 2, October 2001 (2001-10-01), pages 166 - 173, XP002199242, ISSN: 1061-4036 *

Also Published As

Publication number Publication date
WO2002030966A2 (en) 2002-04-18
AU2001296584A1 (en) 2002-04-22

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