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WO2002026996A3 - Regulation d'enzyme humaine de type phospholipase c specifique du phosphatidylinositol - Google Patents

Regulation d'enzyme humaine de type phospholipase c specifique du phosphatidylinositol Download PDF

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Publication number
WO2002026996A3
WO2002026996A3 PCT/EP2001/011012 EP0111012W WO0226996A3 WO 2002026996 A3 WO2002026996 A3 WO 2002026996A3 EP 0111012 W EP0111012 W EP 0111012W WO 0226996 A3 WO0226996 A3 WO 0226996A3
Authority
WO
WIPO (PCT)
Prior art keywords
enzyme
specific phospholipase
human phosphatidylinositol
regulation
reagents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2001/011012
Other languages
English (en)
Other versions
WO2002026996A2 (fr
Inventor
Zhimin Zhu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Priority to AU2002210514A priority Critical patent/AU2002210514A1/en
Publication of WO2002026996A2 publication Critical patent/WO2002026996A2/fr
Publication of WO2002026996A3 publication Critical patent/WO2002026996A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne des réactifs qui permettent de réguler une enzyme humaine de type phospholipase C spécifique du phosphatidylinositol ainsi que des réactifs qui se lient aux produits géniques de cette enzyme, et qui peuvent jouer un rôle dans la prévention, l'amélioration ou la correction de dysfonctionnements ou de maladies comprenant, notamment, l'asthme, le cancer, des troubles du système nerveux central, et la broncho-pneumopathie chronique obstructive.
PCT/EP2001/011012 2000-09-27 2001-09-24 Regulation d'enzyme humaine de type phospholipase c specifique du phosphatidylinositol Ceased WO2002026996A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002210514A AU2002210514A1 (en) 2000-09-27 2001-09-24 Regulation of human phosphatidylinositol-specific phospholipase c-like enzyme

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23555200P 2000-09-27 2000-09-27
US60/235,552 2000-09-27

Publications (2)

Publication Number Publication Date
WO2002026996A2 WO2002026996A2 (fr) 2002-04-04
WO2002026996A3 true WO2002026996A3 (fr) 2002-09-26

Family

ID=22885960

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/011012 Ceased WO2002026996A2 (fr) 2000-09-27 2001-09-24 Regulation d'enzyme humaine de type phospholipase c specifique du phosphatidylinositol

Country Status (2)

Country Link
AU (1) AU2002210514A1 (fr)
WO (1) WO2002026996A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0127206D0 (en) * 2001-11-13 2002-01-02 Univ Liverpool Treatment of inflammatory conditions
WO2004003189A2 (fr) * 2002-06-26 2004-01-08 Bayer Healthcare Ag Regulation de phospholipase c humaine
US20100284992A1 (en) * 2006-10-02 2010-11-11 The Regents Of The University Of Colorado, A Body Corporate Phospholipase C and Method of Use

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001075067A2 (fr) * 2000-03-31 2001-10-11 Hyseq, Inc. Nouveaux acides nucleiques et polypeptides

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001075067A2 (fr) * 2000-03-31 2001-10-11 Hyseq, Inc. Nouveaux acides nucleiques et polypeptides

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE SWISSPROT [online] 1 July 1989 (1989-07-01), SUH ET AL.: "1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE DELTA 1 (EC 3.1.4.11) (PLC-DELTA-1) (PHOSPHOLIPASE C-DELTA-1) (PLC-III).", XP002199648, Database accession no. P10688 *
DATABASE SWISSPROT [online] 1 May 2000 (2000-05-01), KIKUNO ET AL.: "KIAA1069 Protein (Fragment)", XP002199647, Database accession no. Q9UPT3 *
KIKUNO ET AL.: "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.", DNA RESEARCH, vol. 6, 1999, pages 197 - 205, XP000852618 *

Also Published As

Publication number Publication date
WO2002026996A2 (fr) 2002-04-04
AU2002210514A1 (en) 2002-04-08

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