[go: up one dir, main page]

WO2002022210A1 - Procede et dispositif de verification d'irradiation therapeutique - Google Patents

Procede et dispositif de verification d'irradiation therapeutique Download PDF

Info

Publication number
WO2002022210A1
WO2002022210A1 PCT/EP2001/009483 EP0109483W WO0222210A1 WO 2002022210 A1 WO2002022210 A1 WO 2002022210A1 EP 0109483 W EP0109483 W EP 0109483W WO 0222210 A1 WO0222210 A1 WO 0222210A1
Authority
WO
WIPO (PCT)
Prior art keywords
modulation
target volume
verification
energy beam
designed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2001/009483
Other languages
German (de)
English (en)
Inventor
Bernd-Michael Hesse
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Deutsches Krebsforschungszentrum DKFZ
Original Assignee
Deutsches Krebsforschungszentrum DKFZ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Deutsches Krebsforschungszentrum DKFZ filed Critical Deutsches Krebsforschungszentrum DKFZ
Priority to AU2002210443A priority Critical patent/AU2002210443A1/en
Publication of WO2002022210A1 publication Critical patent/WO2002022210A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
    • A61N2005/1061—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam using an x-ray imaging system having a separate imaging source

Definitions

  • the invention relates to a method for verifying therapeutic radiation by means of a high-energy modulated beam, the shape of the beam being detected between a device for radiation modulation and the target volume to be irradiated for the verification.
  • the invention further relates to a device for verifying therapeutic radiation by means of a high-energy modulated beam, this being detected for verification by means of a medium which is arranged between a device for radiation modulation and the target volume to be irradiated
  • the most frequently proposed method for verifying therapeutic radiation is based on the detection of the high-energy beam by means of transit dosimetry.
  • the medium for recording the high-energy modulated beam is arranged below the patient table, so that the beam is only recorded when it has passed through the patient's body.
  • the following proposals of the prior art are based on transit dosimetry: US Pat. No. 4,726,046 A; US 5,825,845 A; US 5,471,516 A; US 5, 278, 886 A and TR Mackie et al ("Tomotherapy: A new concept for the delivery of dynamic conformal radiotherapy", Med.Phy.20 (1993) 1709-1719) and by David A. Jaffray et al.
  • the therapy beam only reaches this position after a further rotation of 90 °.
  • the location and shape of the target volume e.g. B. changed by breathing, heartbeat, muscle tension, etc. This leads to an inaccuracy and thus to an inadequate correction, so that even with this method an optimal error-free irradiation is not guaranteed.
  • the aforementioned problem of time offset also exists in the subject of DE 197 81 999 Tl.
  • a field light is arranged at the radiation source and a reference structure is placed around the patient and fixed to the patient.
  • the collimator opening prepared for the irradiation is then imaged on the reference structure by means of the field light. This image is compared with the treatment plan for verification and, if there is agreement, the irradiation is carried out.
  • the high-energy modulated beam is not detected at all, but the field light that is sent through the same collimator opening.
  • the resulting large time offset excludes short-term changes, such as those B. caused by heartbeat, breathing or sudden muscle tension, completely out.
  • WO 99 32 189 AI deals with verification, but with a magnetic resonance tomography device that differs significantly from the above. Verification procedure differs because the patient lies in the magnetic resonance imaging device.
  • a prompt verification by a magnetic resonance tomography device is in any case questionable because irradiation with accelerated particles - and this is the rule with an energy-rich therapy beam - is deflected by the magnetic fields of the magnetic resonance tomography device and the latter cannot be switched on and off for a short time.
  • the object of the invention is therefore to improve the verification of the radiation to be applied, in particular to enable an exact check of the conformity of the radiation applied with the radiation predetermined by the treatment plan, in order to be able to correct the therapy beam better and even with slight deviations ,
  • An additional task consists in designing the verification in such a way that it is possible to check as soon as possible in order to optimally adapt the therapy beam to the actual state.
  • the object is achieved in that an X-ray beam is designed to detect the target volume, which is directed in the opposite direction to that of the high-energy beam to the target volume and that the direction of the X-ray beam is detected behind the target volume, the detection of the Target volume is used by the X-ray beam to verify and correct the modulation of the high-energy beam.
  • the object is achieved in that in order to verify the correspondence of the shape of the high-energy modulated beam with the shape and position of the target volume, a radiation source for an X-ray beam is arranged opposite to the target volume of the radiation source for the high-energy beam in such a way that the directions of the rays are opposite and that a medium for detecting the X-ray beam is arranged behind the target volume with respect to the direction thereof.
  • the therapy beam is detected before it passes through the patient and thus without being falsified by scattering, whereby an exact detection of the contour of the beams which are generally to be applied successively from different directions is possible.
  • the verification is carried out using an x-ray beam that is exactly opposite to the therapy beam, so that there is no difference in angle between the therapy beam and the x-ray beam used for verification.
  • the therapy beam and the X-ray beam can be sent and recorded almost simultaneously.
  • the invention is further developed in such a way that the intensity of the beam is also detected, in that the medium that detects the beam is also designed to detect the intensity of the beam, then this too can be exactly verified, since no absorption of parts of the rays can occur before it is detected ,
  • the additional object is achieved in that the verification and correction of the modulation of the high-energy beam is carried out on the basis of an X-ray beam recorded almost simultaneously.
  • the method and the device are designed in such a way that, in the case of a pulsed high-energy beam, the X-ray beam is detected in the transmission pauses of the high-energy beam. This enables an exact detection of the X-ray radiation without scattered rays of the high-energy beam. In order to keep the radiation exposure as low as possible, it is furthermore expedient if the X-ray beam is only emitted in the transmission pauses of the high-energy beam. '
  • the detection of the target volume by the X-ray beam is expediently used to verify and correct the modulation of the high-energy beam.
  • This can be done, for example, by the data from the detection by the X-rays being used immediately to correct the setting of a collimator, for example a multileaf coimulator.
  • the corrections are the more precise the sooner they are implemented. Since the pulses of the energy rich beam in the microsecond range and the pauses in the millisecond range, this is the lower limit for the simultaneousness of the time when the transmission of the high-energy beam is detected. With a high computing speed of the computer used, it is possible to achieve such a proximity in time that no relevant changes take place during these periods. This enables optimal accuracy to be achieved.
  • the invention not only limits the verification to checking whether the applied beam corresponds to the planned one, the method and device are expediently designed in such a way that the anatomy and position of the patient can also be detected by the X-ray beam and that it can also be verified. whether the patient's anatomy and its position at the time of irradiation correspond to the anatomy and position on which the treatment plan was based.
  • An almost time-identical verification of the anatomy and position and thus compliance with the treatment plan for example its timely adaptation to the anatomy and position of the patient, is made possible so that changes can be taken into account without delay. It is possible to include the changes in the correction of the therapy beam or to switch off the therapy beam.
  • the target volume - even if it changes its position and / or shape - receives the predetermined radiation dose with high accuracy and the dose falls exactly at the edge of the target volume - usually the tumor edge - so steeply that surrounding tissue is not damaged if possible.
  • the invention increases the success of therapy and at the same time reduces the side effects.
  • tumors that directly border on risk organs can be treated better and at a significantly reduced risk.
  • the invention also makes it possible to dispense with a strict fixation of the patient, since changes in the patient's position can also be detected and included in the correction. It is then no longer necessary to store a patient in tightly fitting rigid trays, which do Take the opportunity, but ultimately can not give a complete guarantee of an unchanged anatomy, since breathing movements, muscle tension and the displacement of organs are always present. All of this can be detected and taken into account by using the above-mentioned further development of the verification according to the invention.
  • the treatment can be continued or even interrupted if there are deviations, the latter if a sufficiently rapid correction is not possible.
  • the method and device be designed such that the shape of the target volume is detected from different directions by means of an X-ray beam before the irradiation with the high-energy beam, and that this information is included in the verification and correction of the modulation of the high energy beam.
  • treatment plans usually provide for different areas to be treated with a different radiation dose, these areas are expediently included in the verification and correction of the modulation of the high-energy beam.
  • risk organs In order to optimally protect risk organs, it is further proposed to also record them in one of the aforementioned ways and to take them into account when verifying and correcting the modulation of the high-energy beam. It is expedient if the position and shape of risk organs are determined almost simultaneously with the verification and modulation of the high-energy beam by the X-ray beam and taken into account for a correction of the modulation.
  • both media that for recording the high-energy beam and that for recording the X-ray beam, are designed as one medium.
  • the individual detection elements can also be used for the detection of both beams, in that the X-rays are detected, for example, directly on the surface and the therapy beam when the medium is transmitted through.
  • the medium must consist of a material that is not damaged by the hard therapy beam.
  • the medium can be an array of photodiodes, the latter consisting of amorphous silicon. These cannot destroy a lattice structure. If these photodiodes are arranged in a plastic housing, there is no significant weakening or scattering of the rays to be detected.
  • the device according to the invention is preferably designed in such a way that the radiation sources, the device for radiation modulation and the medium or the media for detecting the beams are arranged on a gantry, as a result of which they can jointly take different directions to the target volume.
  • the most expedient is the arrangement of a medium for recording both rays, which leads to the above. Advantages leads. If the radiation source for the X-ray beam and a medium for recording both beams are attached to a conventional radiation device, the device according to the invention can be produced in a simple manner and it is possible to roast existing devices.
  • the device can furthermore have a computer which is designed and set up for the verification and correction of the modulation of the high-energy beam on the basis of the data recorded by the medium or the media.
  • a computer which is designed and set up for the verification and correction of the modulation of the high-energy beam on the basis of the data recorded by the medium or the media.
  • the computer is preferably designed or set up for almost simultaneous verification and correction. Also for the inclusion of previously determined anatomical data in the almost simultaneous verification and correction.
  • FIG. 1 is a schematic diagram of an exemplary embodiment of the invention
  • Fig. 2 shows a device according to the invention in use
  • An energy-rich beam 1 is generated by a radiation source 11 and modulated by a device for radiation modulation 2, for example a multileaf collimator, in accordance with the treatment plan and directed onto a target volume 3.
  • a device for radiation modulation 2 for example a multileaf collimator
  • this is a tumor of a patient 21 who is treated lying on a patient table 19.
  • a medium 8 for detecting the high-energy modulated beam 1 is arranged in the beam path 9 between the device 2 for beam modulation and the patient 21, so that the shape and intensity modifications can be detected and monitored by the device 2 for beam modulation. If the modulation of the beam 1 deviates from its target value, it can be switched off or corrected.
  • a radiation source 10 for an X-ray beam 4 is arranged opposite the radiation source 11 for the high-energy beam 1.
  • the arrangement is such that a beam path 9 is formed in which the direction 5 of the X-ray beam 4 is exactly opposite to the direction 6 of the high-energy beam 1.
  • the x-ray beam 4 is used to record the target volume 3 and the anatomy and position of the patient 21 in the manner already described above.
  • a medium 12 is arranged to record the X-ray beam 4 after it has passed through the patient 21.
  • the media 8 and 12 are expediently designed as a medium 13 for detecting the high-energy beam 1 and the X-ray beam 4.
  • the radiation sources 11 and 10 are arranged in such a way that the target volume 3 is detected by the therapy beam 1 and the target volume 3 and its surroundings by the X-ray beam 4, which should also be taken into account when modulating the therapy beam 1. For this reason, the x-ray beam 4 is drawn further apart than the therapy beam 1, although it can of course also be made narrower than drawn, that is, it does not have to cover the entire patient 21.
  • a detection medium 13 If a detection medium 13 is provided, its area must be dimensioned such that it detects the conically diverging beams 1 and 4 in the position of the arrangement of the detection medium 13.
  • a treatment is expediently carried out in the following steps:
  • a current computer tomography data record is obtained from the patient 21 in the therapy situation using the computer tomography system, ie the X-ray beam 4 and a medium 12 or 13, immediately before the start of the radiation therapy.
  • the computer tomography system ie the X-ray beam 4 and a medium 12 or 13, immediately before the start of the radiation therapy.
  • the field shape and the intensity distribution of the therapy beam 1 are measured and logged during the application of the therapy beam fields 24 (see FIG. 3).
  • the radiation dose distribution 16, 16 ', 16 "(see FIG. 3) applied to the patient 21 can be reconstructed and verified online.
  • the radiation application can be interrupted in the event of any deviations or with corresponding ones
  • the type of arrangement of the X-ray source 10 and the medium 13 for detecting the beams 1 and 4 also makes it possible to determine the relative position of structures (target volume 3, areas 16, 16 'to be irradiated with different doses , 16 "of target volume 3 and risk organs 17) with to monitor low contrast (soft tissue contrast) in the therapy radiation field 24 and its surroundings (see FIG. 3) with the aid of the X-ray beam 4 during the application of the individual therapy radiation fields 24 and, if possible, to carry out an immediate, as nearly as possible, correction.
  • FIG. 2 shows a device according to the invention in use.
  • This is a customary design of a radiation device 18 with a radiation source 11 for the therapy beam 1, a patient table 19 and a device 2 for radiation modulation in order to direct the medically indicated radiation onto a target volume 3, for example on the head 20 of a patient 21 aim that a tumor is maximally damaged and the surrounding tissue is maximally protected.
  • a frame (gantry) 14 is provided which can encircle the patient 21 on all sides.
  • the gantry 14 contains the radiation source 11 for the therapy beam 1, the high-energy radiation 1 being generated, for example, by a linear accelerator 22.
  • Opposite the radiation source 11, the radiation source 10 for the X-ray beam 4 is arranged on the gantry 14 in the manner already described for FIG. 1.
  • the gantry 14 can be rotated about a horizontal axis of rotation 23, the beams 1 and 4 being aimed at the target volume 3 or its surroundings.
  • the target volume 3 is located in the isocenter of the rays 1 and 4, the radiation sources 11 and 10 and a device 2 for radiation modulation orbiting the patient 21 by rotating the gantry 14 about the axis 23.
  • the treatment table 19 can be shifted or rotated in order to make an exact adjustment of the irradiation of the therapy beam 1 to the target volume 3 of the patient 21.
  • a gantry The purpose of such a gantry is that the different irradiation directions 7 (see FIG. 3) give the target volume 3 maximum irradiation, but the surrounding tissue is protected as much as possible, since it is only ever briefly is exposed to high-energy radiation 1 at an early stage.
  • the position and the profile of the target volume 3 as well as the position of risk organs 17 or of areas 16, 16 ', 16 "which are intended for different radiation doses is detected by the medium 13 with the aid of the X-ray beam 4.
  • the actual state is also recorded of the modeled therapy beam 1.
  • These data are converted in such a way that the collimator 2 forms a corresponding collimator opening, the exact shape of the target volume 3 with the desired radiation dose distribution 16, 16 ', 16 "being obtained by the detection and verification according to the invention (see FIG. 3 ) can be irradiated.
  • the radiation dose distribution 16, 16 ', 16 " is achieved in that one or more therapy radiation fields 24 of different duration are also applied from several directions 7.
  • a computer 15 is provided, which is set up on the basis of radiation planning and ongoing verification in such a way that it controls the gantry 14, the device 2 for radiation modulation and possibly also the patient table 21.
  • the device 2 can be both a collimator and a scanner.
  • the therapy beam fields 24 to be treated in each case are limited by the collimator or generated by scanning a therapy beam 1.
  • FIG. 3 shows an explanation of the principle of tumor radiation, with the application of medically indicated high-energy radiation 1 from different directions 7.
  • a target volume 3 to be irradiated for example a tumor
  • the device 2 for radiation modulation serves this purpose, which can be designed as a collimator or as a scanner.
  • the therapy radiation fields 24 are formed as matrices 25 from individual fields 26 with a different radiation dose.
  • Such matrices 25 can be reproduced in almost any conceivable form by means of the leaf adjustments of a multileaf co-simulator, the thinest possible replication of the therapy radiation fields 24 to be irradiated being achieved.
  • several different therapy radiation fields 24 with different periods of time can be applied from one direction 7 in order to optimally achieve areas 16, 16 ', 16 "with a different radiation dose. In this process, the almost time-identical verification and correction takes place in FIG already described above instead.
  • the representation of the figures is only an exemplary representation of the invention. It would also be conceivable that the therapy radiation fields 24 are generated by a scanner instead of by a collimator. Then this serves as a device 2 for radiation modulation and the medium 8 or 13 must record the scanned therapy radiation fields 24 so that the verification according to the invention and a correction, and possibly also a termination of the treatment, can take place in a corresponding manner. Of course, further configurations are also conceivable which make use of the basic idea of the invention.
  • High-energy modulated beam (therapy beam) Device for modulating the beam
  • Target volume X-ray beam Direction of the X-ray beam Direction of the high-energy beam
  • Different directions of detection and irradiation of the target volume Medium for recording the high-energy modulated beam Beam path 0
  • Radiation source for high-energy beam 2 Medium for recording the X-ray beam 3

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

L'invention concerne un procédé et un dispositif permettant de vérifier une irradiation thérapeutique au moyen d'un faisceau (1) modulé à grande énergie. Selon ce procédé, la vérification implique de détecter la forme du faisceau (1) entre un dispositif de modulation du faisceau (2) et le volume cible à irradier. En ce qui concerne le dispositif approprié, un milieu (8,13) destiné à détecter le faisceau modulé à grande énergie est disposé entre un dispositif de modulation du faisceau (2) et le volume cible (3) à irradier. La vérification du rayonnement à appliquer se trouve améliorée du fait qu'un faisceau de rayons X est formé pour détecter le volume cible (3), qui est dirigé sur le volume cible (3), en sens inverse (5) au sens (6) du faisceau à grande énergie (1). Le faisceau de rayons X (4) est détecté derrière le volume cible (3), en ce qui concerne sa direction (5). La détection du volume cible (3) par le faisceau de rayons X (4) sert à vérifier et à corriger la modulation du faisceau à grande énergie (1).
PCT/EP2001/009483 2000-09-15 2001-08-17 Procede et dispositif de verification d'irradiation therapeutique Ceased WO2002022210A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002210443A AU2002210443A1 (en) 2000-09-15 2001-08-17 Method and device for verifying a therapeutic irradiation

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE10045797 2000-09-15
DE10045797.5 2000-09-15
DE10100958A DE10100958C2 (de) 2000-09-15 2001-01-11 Vorrichtung zur Verifikation einer therapeutischen Bestrahlung
DE10100958.5 2001-01-11

Publications (1)

Publication Number Publication Date
WO2002022210A1 true WO2002022210A1 (fr) 2002-03-21

Family

ID=26007069

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/009483 Ceased WO2002022210A1 (fr) 2000-09-15 2001-08-17 Procede et dispositif de verification d'irradiation therapeutique

Country Status (3)

Country Link
AU (1) AU2002210443A1 (fr)
DE (1) DE10100958C2 (fr)
WO (1) WO2002022210A1 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003076016A1 (fr) * 2002-03-12 2003-09-18 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Dispositif pour mettre en oeuvre et verifier un traitement therapeutique et programme informatique et procede de commande associes
WO2009072124A1 (fr) * 2007-12-05 2009-06-11 Navotek Medical Ltd. Détection de photons en présence d'un faisceau de rayonnement pulsé
US11135452B2 (en) 2018-05-02 2021-10-05 Shanghai United Imaging Healthcare Co., Ltd. Radiation systems for radiation treatment and imaging

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4726046A (en) 1985-11-05 1988-02-16 Varian Associates, Inc. X-ray and electron radiotherapy clinical treatment machine
US5233990A (en) * 1992-01-13 1993-08-10 Gideon Barnea Method and apparatus for diagnostic imaging in radiation therapy
US5278886A (en) 1992-01-16 1994-01-11 Hitachi Medical Corporation Radiosurgery effecting position correction of collimator
US5471516A (en) 1994-10-06 1995-11-28 Varian Associates, Inc. Radiotherapy apparatus equipped with low dose localizing and portal imaging X-ray source
US5538494A (en) 1994-03-17 1996-07-23 Hitachi, Ltd. Radioactive beam irradiation method and apparatus taking movement of the irradiation area into consideration
EP0773042A2 (fr) * 1993-06-09 1997-05-14 Wisconsin Alumni Research Foundation Atténuateur de rayonnement multifeuille pour la radiothérapie doté d'un système de vérification
US5825845A (en) 1996-10-28 1998-10-20 Loma Linda University Medical Center Proton beam digital imaging system
WO1999032189A1 (fr) 1997-12-19 1999-07-01 Varian Associates, Inc. Equipement de radiotherapie comportant un systeme d'imagerie par resonance magnetique
DE19781999T1 (de) 1996-09-20 1999-08-12 Eric R Cosman Strahlungsbündel-Steuersystem
JP2000167072A (ja) * 1998-12-03 2000-06-20 Mitsubishi Electric Corp 動体追跡照射装置

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4726046A (en) 1985-11-05 1988-02-16 Varian Associates, Inc. X-ray and electron radiotherapy clinical treatment machine
US5233990A (en) * 1992-01-13 1993-08-10 Gideon Barnea Method and apparatus for diagnostic imaging in radiation therapy
US5278886A (en) 1992-01-16 1994-01-11 Hitachi Medical Corporation Radiosurgery effecting position correction of collimator
EP0773042A2 (fr) * 1993-06-09 1997-05-14 Wisconsin Alumni Research Foundation Atténuateur de rayonnement multifeuille pour la radiothérapie doté d'un système de vérification
US5538494A (en) 1994-03-17 1996-07-23 Hitachi, Ltd. Radioactive beam irradiation method and apparatus taking movement of the irradiation area into consideration
US5471516A (en) 1994-10-06 1995-11-28 Varian Associates, Inc. Radiotherapy apparatus equipped with low dose localizing and portal imaging X-ray source
DE19781999T1 (de) 1996-09-20 1999-08-12 Eric R Cosman Strahlungsbündel-Steuersystem
US5825845A (en) 1996-10-28 1998-10-20 Loma Linda University Medical Center Proton beam digital imaging system
WO1999032189A1 (fr) 1997-12-19 1999-07-01 Varian Associates, Inc. Equipement de radiotherapie comportant un systeme d'imagerie par resonance magnetique
US6307914B1 (en) * 1998-03-12 2001-10-23 Mitsubishi Denki Kabushiki Kaisha Moving body pursuit irradiating device and positioning method using this device
JP2000167072A (ja) * 1998-12-03 2000-06-20 Mitsubishi Electric Corp 動体追跡照射装置

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MACKIE T R ET AL: "TOMOTHERAPY: A NEW CONCEPT FOR THE DELIVERY OF DYNAMIC CONFORMAL RADIOTHERAPY", MEDICAL PHYSICS, AMERICAN INSTITUTE OF PHYSICS. NEW YORK, US, vol. 20, no. 6, 1 November 1993 (1993-11-01), pages 1709 - 1719, XP000422132, ISSN: 0094-2405 *

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003076016A1 (fr) * 2002-03-12 2003-09-18 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Dispositif pour mettre en oeuvre et verifier un traitement therapeutique et programme informatique et procede de commande associes
US6993112B2 (en) 2002-03-12 2006-01-31 Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts Device for performing and verifying a therapeutic treatment and corresponding computer program and control method
WO2009072124A1 (fr) * 2007-12-05 2009-06-11 Navotek Medical Ltd. Détection de photons en présence d'un faisceau de rayonnement pulsé
WO2009076241A1 (fr) * 2007-12-05 2009-06-18 Navotek Medical Ltd. Procédures et dispositifs pour détecter des photons en présence d'un faisceau de linac
US8193508B2 (en) 2007-12-05 2012-06-05 Navotek Medical Ltd. Detecting photons in the presence of a pulsed radiation beam
US11135452B2 (en) 2018-05-02 2021-10-05 Shanghai United Imaging Healthcare Co., Ltd. Radiation systems for radiation treatment and imaging
US11612767B2 (en) 2018-05-02 2023-03-28 Shanghai United Imaging Healthcare Co., Ltd. Radiation systems for radiation treatment and imaging
US12246193B2 (en) 2018-05-02 2025-03-11 Shanghai United Imaging Healthcare Co., Ltd. Radiation systems for radition treatment and imaging

Also Published As

Publication number Publication date
DE10100958C2 (de) 2003-05-15
AU2002210443A1 (en) 2002-03-26
DE10100958A1 (de) 2002-04-04

Similar Documents

Publication Publication Date Title
EP1483022B1 (fr) Dispositif pour mettre en oeuvre et verifier un traitement therapeutique et programme informatique associes
EP1973606B1 (fr) Installation pour irradier un tissu tumoral chez un patient au moyen d'un faisceau de particules
DE69429566T2 (de) Verfahren und Vorrichtung zum Prüfen der Position einer Verletzung
DE69026406T2 (de) Gerät zur therapeutischen Bestrahlung einer vorgewählten Fläche unter Anwendung eines diagnose computer gestützten Tomography-Scanners
EP1238684B1 (fr) Procédé de création ou de mise à jour d'un plan de traitement d'irradiation
DE69130710T2 (de) Vorrichtung zur stereotaktischen chirurgie und verfahren zur steuerung der vorrichtung
DE69530423T2 (de) Mehrfach-fixierung bei einem rahmenlosen stereotaxieverfahren
EP2279776B1 (fr) Fantôme destiné à la validation in vitro expérimentale de rayonnements sous l'influence de mouvements en fonction de la dose biologique effective
EP2307096B1 (fr) Dispositif et procédé pour évaluer une répartition d'activité et installation d'irradiation
EP2482926B1 (fr) Procédé et dispositif pour vérifier un programme de traitement par rayonnement et installation de traitement par rayonnement
DE102014207906A1 (de) Bildgeführte Strahlentherapie
EP1380262A1 (fr) Système de positionnement d'un patient pour thérapie par radiation/radio chirurgie basé sur un dispositif de rayon x stéréoscopique
DE10051370A1 (de) Verfahren und Vorrichtung zur exakten Patientenpositionierung in der Strahlentherapie und Radiochirurgie
DE10033063A1 (de) Verfahren zur atmungskompensierten Strahlenbehandlung
EP1455898A2 (fr) Systeme de radiotherapie
DE102007011154A1 (de) Phantom und Verfahren für die Qualitätsüberprüfung einer medizintechnischen Anlage sowie Partikeltherapieanlage
DE10250655A1 (de) Patientenpositionierungssystem, das eine Oberflächenfotogrammetrie verwendet
DE102014210458B4 (de) Ermittlung einer Position einer zu bestrahlenden Zielregion eines Patienten in einer Bestrahlungseinrichtung
DE102009032429B4 (de) Strahlentherapiegerät mit rotierbarer Gantry
DE102008057145A1 (de) Patiententransporteinheit und Verfahren zum Transport eines Patienten
DE10313934A1 (de) Verifikation von Strahlungs- und Lichtfeldkongruenz
DE10100958C2 (de) Vorrichtung zur Verifikation einer therapeutischen Bestrahlung
EP1479411B1 (fr) Dispostif d'irradiation de tumeur controlée
DE102011081422B4 (de) Bildgestützte Strahlentherapie
DE102011080364B4 (de) Kontrastmittel-verstärkte Bildgebung bei der Strahlentherapie

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PH PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP