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WO2002021074A3 - Optical amplification in coherence reflectometry - Google Patents

Optical amplification in coherence reflectometry Download PDF

Info

Publication number
WO2002021074A3
WO2002021074A3 PCT/DK2001/000573 DK0100573W WO0221074A3 WO 2002021074 A3 WO2002021074 A3 WO 2002021074A3 DK 0100573 W DK0100573 W DK 0100573W WO 0221074 A3 WO0221074 A3 WO 0221074A3
Authority
WO
WIPO (PCT)
Prior art keywords
light field
reflected light
sample arm
well
combining means
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/DK2001/000573
Other languages
French (fr)
Other versions
WO2002021074A2 (en
Inventor
Peter E Andersen
Anders Bjarklev
Andreas Tycho
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Riso National Laboratory
Original Assignee
Riso National Laboratory
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Riso National Laboratory filed Critical Riso National Laboratory
Priority to AU8571801A priority Critical patent/AU8571801A/en
Priority to US10/363,323 priority patent/US6853457B2/en
Priority to EP01964941A priority patent/EP1432960A2/en
Priority to AU2001285718A priority patent/AU2001285718B2/en
Priority to CA002421113A priority patent/CA2421113C/en
Publication of WO2002021074A2 publication Critical patent/WO2002021074A2/en
Anticipated expiration legal-status Critical
Publication of WO2002021074A3 publication Critical patent/WO2002021074A3/en
Ceased legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47Scattering, i.e. diffuse reflection
    • G01N21/4795Scattering, i.e. diffuse reflection spatially resolved investigating of object in scattering medium
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01BMEASURING LENGTH, THICKNESS OR SIMILAR LINEAR DIMENSIONS; MEASURING ANGLES; MEASURING AREAS; MEASURING IRREGULARITIES OF SURFACES OR CONTOURS
    • G01B9/00Measuring instruments characterised by the use of optical techniques
    • G01B9/02Interferometers
    • G01B9/0209Low-coherence interferometers
    • G01B9/02091Tomographic interferometers, e.g. based on optical coherence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062Arrangements for scanning
    • A61B5/0066Optical coherence imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • A61B5/0086Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters using infrared radiation

Landscapes

  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

The present invention relates to an apparatus and a method for optical coherence reflectometry, in particular for optical coherence tomography. The invention particularly relates to the route of the light field in the sample arm. The reflected light field in the sample arm is amplified before being received by a combining means, said combining means being capable of receiving the reflected light field from the sample arm as well as the second reflected light field from the reference arm. Thereby, it is possible to direct substantially all light energy in the sample arm to the combining means, and to obtain fully the utilisation of the amplification of the reflected light field since preferably only the reflected light field is amplified by the optical amplifier. This leads to an improved signal-to-noise ratio (SNR) whereby an increase of the maximal penetration depth is obtained. Thereby, the apparatus is useful for obtaining optical biopsies of transparent as well as non-transparent tissues as well as new technical fields wherein the increased SNR allows the use of the present apparatus.
PCT/DK2001/000573 2000-09-04 2001-09-04 Optical amplification in coherence reflectometry Ceased WO2002021074A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
AU8571801A AU8571801A (en) 2000-09-04 2001-09-04 Optical amplification in coherence reflectometry
US10/363,323 US6853457B2 (en) 2000-09-04 2001-09-04 Optical amplification in coherence reflectometry
EP01964941A EP1432960A2 (en) 2000-09-04 2001-09-04 Optical amplification in coherence reflectometry
AU2001285718A AU2001285718B2 (en) 2000-09-04 2001-09-04 Optical amplification in coherence reflectometry
CA002421113A CA2421113C (en) 2000-09-04 2001-09-04 Optical amplification in coherence reflectometry

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200001318 2000-09-04
DKPA200001318 2000-09-04

Publications (2)

Publication Number Publication Date
WO2002021074A2 WO2002021074A2 (en) 2002-03-14
WO2002021074A3 true WO2002021074A3 (en) 2004-04-15

Family

ID=8159694

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DK2001/000573 Ceased WO2002021074A2 (en) 2000-09-04 2001-09-04 Optical amplification in coherence reflectometry

Country Status (5)

Country Link
US (1) US6853457B2 (en)
EP (1) EP1432960A2 (en)
AU (2) AU2001285718B2 (en)
CA (1) CA2421113C (en)
WO (1) WO2002021074A2 (en)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003307458A (en) * 2002-04-15 2003-10-31 Akifumi Ito Method and apparatus for measuring temperature of substrate
US7102758B2 (en) 2003-05-06 2006-09-05 Duke University Fourier domain low-coherence interferometry for light scattering spectroscopy apparatus and method
US7840098B2 (en) * 2005-01-20 2010-11-23 Intel Corporation Variable optical power limiter
JP4628820B2 (en) * 2005-02-25 2011-02-09 サンテック株式会社 Wavelength scanning fiber laser light source
US8456738B2 (en) * 2005-04-14 2013-06-04 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Ultrahigh-resolution fiber-optic confocal microscope and method
US20060293644A1 (en) * 2005-06-21 2006-12-28 Donald Umstadter System and methods for laser-generated ionizing radiation
WO2007002898A2 (en) * 2005-06-29 2007-01-04 University Of South Florida Variable tomographic scanning with wavelength scanning digital interface holography
US8537366B2 (en) 2005-10-11 2013-09-17 Duke University Systems and methods for endoscopic angle-resolved low coherence interferometry
WO2007044821A1 (en) * 2005-10-11 2007-04-19 Duke University Systems and method for endoscopic angle-resolved low coherence interferometry
JP4887989B2 (en) * 2005-12-02 2012-02-29 ナノフォトン株式会社 Optical microscope and spectrum measuring method
WO2008011580A2 (en) * 2006-07-21 2008-01-24 Oncoscope, Inc. Protective probe tip, particularly for use on a fiber-optic probe used in an endoscopic application
EP2139392B1 (en) * 2007-04-26 2014-02-26 Koninklijke Philips N.V. Localization system
AU2008298551A1 (en) * 2007-09-13 2009-03-19 Duke University Apparatuses, systems, and methods for low-coherence interferometry (LCI)
WO2009089344A1 (en) * 2008-01-08 2009-07-16 Oncoscope, Inc. Systems and methods for tissue examination, diagnostic, treatment, and/or monitoring
US8644913B2 (en) 2011-03-28 2014-02-04 Avinger, Inc. Occlusion-crossing devices, imaging, and atherectomy devices
US8062316B2 (en) 2008-04-23 2011-11-22 Avinger, Inc. Catheter system and method for boring through blocked vascular passages
US9125562B2 (en) * 2009-07-01 2015-09-08 Avinger, Inc. Catheter-based off-axis optical coherence tomography imaging system
US7896498B2 (en) * 2009-03-30 2011-03-01 Ottawa Hospital Research Institute Apparatus and method for optical measurements
WO2010129075A1 (en) 2009-04-28 2010-11-11 Avinger, Inc. Guidewire support catheter
JP6101078B2 (en) 2009-05-28 2017-03-29 アビンガー・インコーポレイテッドAvinger, Inc. Optical coherence tomography for bioimaging
EP2448502B1 (en) 2009-07-01 2022-04-06 Avinger, Inc. Atherectomy catheter with laterally-displaceable tip
WO2011072068A2 (en) 2009-12-08 2011-06-16 Avinger, Inc. Devices and methods for predicting and preventing restenosis
US9823127B2 (en) 2010-01-22 2017-11-21 Duke University Systems and methods for deep spectroscopic imaging of biological samples with use of an interferometer and spectrometer
CA2787696A1 (en) 2010-01-22 2011-07-28 Adam Wax Multiple window processing schemes for spectroscopic optical coherence tomography (oct) and fourier domain low coherence interferometry
WO2014039096A1 (en) 2012-09-06 2014-03-13 Avinger, Inc. Re-entry stylet for catheter
US11382653B2 (en) 2010-07-01 2022-07-12 Avinger, Inc. Atherectomy catheter
US10548478B2 (en) 2010-07-01 2020-02-04 Avinger, Inc. Balloon atherectomy catheters with imaging
US9345510B2 (en) 2010-07-01 2016-05-24 Avinger, Inc. Atherectomy catheters with longitudinally displaceable drive shafts
US9949754B2 (en) 2011-03-28 2018-04-24 Avinger, Inc. Occlusion-crossing devices
EP2768406B1 (en) 2011-10-17 2019-12-04 Avinger, Inc. Atherectomy catheters and non-contact actuation mechanism for catheters
US9345406B2 (en) 2011-11-11 2016-05-24 Avinger, Inc. Occlusion-crossing devices, atherectomy devices, and imaging
WO2013172970A1 (en) 2012-05-14 2013-11-21 Avinger, Inc. Atherectomy catheters with imaging
EP2849660B1 (en) 2012-05-14 2021-08-25 Avinger, Inc. Atherectomy catheter drive assemblies
EP2849636B1 (en) 2012-05-14 2020-04-22 Avinger, Inc. Optical coherence tomography with graded index fiber for biological imaging
US11284916B2 (en) 2012-09-06 2022-03-29 Avinger, Inc. Atherectomy catheters and occlusion crossing devices
US9498247B2 (en) 2014-02-06 2016-11-22 Avinger, Inc. Atherectomy catheters and occlusion crossing devices
JP6291025B2 (en) 2013-03-15 2018-03-14 アビンガー・インコーポレイテッドAvinger, Inc. Optical pressure sensor assembly
EP2967507B1 (en) 2013-03-15 2018-09-05 Avinger, Inc. Tissue collection device for catheter
US9854979B2 (en) 2013-03-15 2018-01-02 Avinger, Inc. Chronic total occlusion crossing devices with imaging
EP3019096B1 (en) 2013-07-08 2023-07-05 Avinger, Inc. System for identification of elastic lamina to guide interventional therapy
JP6539669B2 (en) 2014-02-06 2019-07-03 アビンガー・インコーポレイテッドAvinger, Inc. Atherectomy catheter and crossing obstruction device
CN107106190B (en) 2014-07-08 2020-02-28 阿维格公司 High-speed chronic total occlusion traversing device
CN107920780B (en) 2015-07-13 2022-01-11 阿维格公司 Micro-molded anamorphic reflective lens for image guided therapy/diagnostic catheter
AU2017212407A1 (en) 2016-01-25 2018-08-02 Avinger, Inc. OCT imaging catheter with lag correction
CN108882948A (en) 2016-04-01 2018-11-23 阿维格公司 Atherectomy catheter with serrated cutter
WO2017210466A1 (en) 2016-06-03 2017-12-07 Avinger, Inc. Catheter device with detachable distal end
WO2018006041A1 (en) 2016-06-30 2018-01-04 Avinger, Inc. Atherectomy catheter with shapeable distal tip
DE102018101554B4 (en) 2018-01-24 2021-04-01 Precitec Gmbh & Co. Kg Device and method for distance measurement for a laser processing system, and laser processing system
EP3781021B1 (en) 2018-04-19 2023-03-22 Avinger, Inc. Occlusion-crossing devices
EP4044942A4 (en) 2019-10-18 2023-11-15 Avinger, Inc. Occlusion-crossing devices
JP2023115662A (en) * 2022-02-08 2023-08-21 古河電気工業株式会社 optical coherence tomography
CN115741721B (en) * 2022-12-16 2025-03-25 武汉科技大学 A robot welding trajectory correction method based on optical low-coherence technology

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5013907A (en) * 1990-03-27 1991-05-07 Tektronix, Inc. Optical time domain testing instrument
US5291267A (en) * 1992-01-22 1994-03-01 Hewlett-Packard Company Optical low-coherence reflectometry using optical amplification
WO1999046557A1 (en) * 1998-03-13 1999-09-16 Optical Biopsy Technologies, Inc. Method and apparatus for measuring optical reflectivity and imaging through a scattering medium

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8713810D0 (en) 1987-06-12 1987-07-15 Hypoguard Uk Ltd Measured dose dispensing device
US5226895A (en) 1989-06-05 1993-07-13 Eli Lilly And Company Multiple dose injection pen
US6501551B1 (en) * 1991-04-29 2002-12-31 Massachusetts Institute Of Technology Fiber optic imaging endoscope interferometer with at least one faraday rotator
US5465147A (en) * 1991-04-29 1995-11-07 Massachusetts Institute Of Technology Method and apparatus for acquiring images using a ccd detector array and no transverse scanner
US5321501A (en) 1991-04-29 1994-06-14 Massachusetts Institute Of Technology Method and apparatus for optical imaging with means for controlling the longitudinal range of the sample
US5956355A (en) 1991-04-29 1999-09-21 Massachusetts Institute Of Technology Method and apparatus for performing optical measurements using a rapidly frequency-tuned laser
US6485413B1 (en) * 1991-04-29 2002-11-26 The General Hospital Corporation Methods and apparatus for forward-directed optical scanning instruments
US5267016A (en) 1991-11-27 1993-11-30 United Technologies Corporation Laser diode distance measurement
US5371587A (en) 1992-05-06 1994-12-06 The Boeing Company Chirped synthetic wavelength laser radar
US5434662A (en) 1993-12-23 1995-07-18 Hughes Aircraft Company Speckle resistant method and apparatus with chirped laser beam
US5459564A (en) * 1994-02-18 1995-10-17 Chivers; James T. Apparatus and method for inspecting end faces of optical fibers and optical fiber connectors
ES2180597T4 (en) 1994-08-18 2003-07-01 Zeiss Carl SURGICAL DEVICE ASSISTED BY OPTICAL COHERENCE TOMOGRAPHY.
US5549575A (en) 1994-09-13 1996-08-27 Becton Dickinson And Company Cartridge retainer assembly for medication delivery pen
US5688251A (en) 1995-09-19 1997-11-18 Becton Dickinson And Company Cartridge loading and priming mechanism for a pen injector
US6020963A (en) 1996-06-04 2000-02-01 Northeastern University Optical quadrature Interferometer
US5908445A (en) 1996-10-28 1999-06-01 Ep Technologies, Inc. Systems for visualizing interior tissue regions including an actuator to move imaging element
US5760901A (en) 1997-01-28 1998-06-02 Zetetic Institute Method and apparatus for confocal interference microscopy with background amplitude reduction and compensation
US6002480A (en) 1997-06-02 1999-12-14 Izatt; Joseph A. Depth-resolved spectroscopic optical coherence tomography
US5921926A (en) 1997-07-28 1999-07-13 University Of Central Florida Three dimensional optical imaging colposcopy
DE19750320C1 (en) 1997-11-13 1999-04-01 Max Planck Gesellschaft Light pulse amplification method
DE19814070B4 (en) 1998-03-30 2009-07-16 Carl Zeiss Meditec Ag Method and arrangement for coherence tomography with increased transversal resolution
US6053613A (en) 1998-05-15 2000-04-25 Carl Zeiss, Inc. Optical coherence tomography with new interferometer
US5975697A (en) 1998-11-25 1999-11-02 Oti Ophthalmic Technologies, Inc. Optical mapping apparatus with adjustable depth resolution
EP1149556B1 (en) * 2000-04-26 2007-08-15 FUJIFILM Corporation Optical tomograph

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5013907A (en) * 1990-03-27 1991-05-07 Tektronix, Inc. Optical time domain testing instrument
US5291267A (en) * 1992-01-22 1994-03-01 Hewlett-Packard Company Optical low-coherence reflectometry using optical amplification
WO1999046557A1 (en) * 1998-03-13 1999-09-16 Optical Biopsy Technologies, Inc. Method and apparatus for measuring optical reflectivity and imaging through a scattering medium

Also Published As

Publication number Publication date
CA2421113C (en) 2009-12-01
WO2002021074A2 (en) 2002-03-14
US20030184758A1 (en) 2003-10-02
AU2001285718B2 (en) 2006-11-02
EP1432960A2 (en) 2004-06-30
US6853457B2 (en) 2005-02-08
CA2421113A1 (en) 2002-03-14
AU8571801A (en) 2002-03-22

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