WO2002016649A3 - Probes and decoder oligonucleotides - Google Patents
Probes and decoder oligonucleotides Download PDFInfo
- Publication number
- WO2002016649A3 WO2002016649A3 PCT/US2001/026519 US0126519W WO0216649A3 WO 2002016649 A3 WO2002016649 A3 WO 2002016649A3 US 0126519 W US0126519 W US 0126519W WO 0216649 A3 WO0216649 A3 WO 0216649A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- reactions
- oligonucleotides
- probes
- decoder
- arrays
- Prior art date
Links
- 108091034117 Oligonucleotide Proteins 0.000 title 1
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 title 1
- 239000000523 sample Substances 0.000 title 1
- 238000006243 chemical reaction Methods 0.000 abstract 3
- 230000003321 amplification Effects 0.000 abstract 1
- 238000003491 array Methods 0.000 abstract 1
- 238000003205 genotyping method Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000003199 nucleic acid amplification method Methods 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Saccharide Compounds (AREA)
Abstract
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2001288393A AU2001288393A1 (en) | 2000-08-25 | 2001-08-27 | Probes and decoder oligonucleotides |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22794800P | 2000-08-25 | 2000-08-25 | |
| US60/227,948 | 2000-08-25 | ||
| US22885400P | 2000-08-29 | 2000-08-29 | |
| US60/228,854 | 2000-08-29 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2002016649A2 WO2002016649A2 (en) | 2002-02-28 |
| WO2002016649A3 true WO2002016649A3 (en) | 2003-03-13 |
Family
ID=26921901
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US2001/026519 WO2002016649A2 (en) | 2000-08-25 | 2001-08-27 | Probes and decoder oligonucleotides |
Country Status (2)
| Country | Link |
|---|---|
| AU (1) | AU2001288393A1 (en) |
| WO (1) | WO2002016649A2 (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6902921B2 (en) | 2001-10-30 | 2005-06-07 | 454 Corporation | Sulfurylase-luciferase fusion proteins and thermostable sulfurylase |
| US6956114B2 (en) | 2001-10-30 | 2005-10-18 | '454 Corporation | Sulfurylase-luciferase fusion proteins and thermostable sulfurylase |
| US7033754B2 (en) | 1998-06-24 | 2006-04-25 | Illumina, Inc. | Decoding of array sensors with microspheres |
| US7211390B2 (en) | 1999-09-16 | 2007-05-01 | 454 Life Sciences Corporation | Method of sequencing a nucleic acid |
| US7244559B2 (en) | 1999-09-16 | 2007-07-17 | 454 Life Sciences Corporation | Method of sequencing a nucleic acid |
| US7323305B2 (en) | 2003-01-29 | 2008-01-29 | 454 Life Sciences Corporation | Methods of amplifying and sequencing nucleic acids |
| US7575865B2 (en) | 2003-01-29 | 2009-08-18 | 454 Life Sciences Corporation | Methods of amplifying and sequencing nucleic acids |
| US12442038B2 (en) | 2024-09-27 | 2025-10-14 | The Johns Hopkins University | Methods and materials for assessing nucleic acids |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7572642B2 (en) | 2001-04-18 | 2009-08-11 | Ambrigen, Llc | Assay based on particles, which specifically bind with targets in spatially distributed characteristic patterns |
| WO2002090599A1 (en) | 2001-05-09 | 2002-11-14 | Genetic Id, Inc. | Universal microarray system |
| JP2003289869A (en) * | 2002-04-02 | 2003-10-14 | Tosoh Corp | Oligonucleotides and detection methods for detection of atypical mycobacterium Mycobacterium avium |
| US7250496B2 (en) * | 2002-11-14 | 2007-07-31 | Rosetta Genomics Ltd. | Bioinformatically detectable group of novel regulatory genes and uses thereof |
| US7195875B2 (en) | 2003-04-18 | 2007-03-27 | Beckman Coulter, Inc. | Oligonucleotide pairs for multiplexed binding assays |
| WO2005098047A2 (en) * | 2004-02-18 | 2005-10-20 | Isis Pharmaceuticals, Inc. | Compositions for use in identification of bacteria |
| CN110016499B (en) | 2011-04-15 | 2023-11-14 | 约翰·霍普金斯大学 | Safe sequencing system |
| CA2889937C (en) | 2012-10-29 | 2020-12-29 | The Johns Hopkins University | Papanicolaou test for ovarian and endometrial cancers |
| WO2017027653A1 (en) | 2015-08-11 | 2017-02-16 | The Johns Hopkins University | Assaying ovarian cyst fluid |
| WO2019067092A1 (en) | 2017-08-07 | 2019-04-04 | The Johns Hopkins University | Methods and materials for assessing and treating cancer |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0799897A1 (en) * | 1996-04-04 | 1997-10-08 | Affymetrix, Inc. (a California Corporation) | Methods and compositions for selecting tag nucleic acids and probe arrays |
| WO1999028505A1 (en) * | 1997-12-03 | 1999-06-10 | Curagen Corporation | Methods and devices for measuring differential gene expression |
| WO2000047767A1 (en) * | 1999-02-11 | 2000-08-17 | Astrazeneca Ab | Oligonucleotide array and methods of use |
-
2001
- 2001-08-27 AU AU2001288393A patent/AU2001288393A1/en not_active Abandoned
- 2001-08-27 WO PCT/US2001/026519 patent/WO2002016649A2/en active Application Filing
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0799897A1 (en) * | 1996-04-04 | 1997-10-08 | Affymetrix, Inc. (a California Corporation) | Methods and compositions for selecting tag nucleic acids and probe arrays |
| WO1999028505A1 (en) * | 1997-12-03 | 1999-06-10 | Curagen Corporation | Methods and devices for measuring differential gene expression |
| WO2000047767A1 (en) * | 1999-02-11 | 2000-08-17 | Astrazeneca Ab | Oligonucleotide array and methods of use |
Non-Patent Citations (7)
| Title |
|---|
| BEN-DOR A ET AL: "Universal DNA tag systems: a combinatorial design scheme.", JOURNAL OF COMPUTATIONAL BIOLOGY: A JOURNAL OF COMPUTATIONAL MOLECULAR CELL BIOLOGY. UNITED STATES 2000, vol. 7, no. 3-4, 2000, pages 503 - 519, XP002948494, ISSN: 1066-5277 * |
| BRENNER S ET AL: "Gene expression analysis by massively parallel signature sequencing (MPSS) on microbead arrays.", NATURE BIOTECHNOLOGY. UNITED STATES JUN 2000, vol. 18, no. 6, June 2000 (2000-06-01), pages 630 - 634, XP002199492, ISSN: 1087-0156 * |
| FAN J B ET AL: "Parallel genotyping of human SNPs using generic high-density oligonucleotide tag arrays.", GENOME RESEARCH. UNITED STATES JUN 2000, vol. 10, no. 6, June 2000 (2000-06-01), pages 853 - 860, XP002934219, ISSN: 1088-9051 * |
| GERRY N P ET AL: "Universal DNA microarray method for multiplex detection of low abundance point mutations.", JOURNAL OF MOLECULAR BIOLOGY. ENGLAND 17 SEP 1999, vol. 292, no. 2, 17 September 1999 (1999-09-17), pages 251 - 262, XP002214482, ISSN: 0022-2836 * |
| GUNDERSON K L ET AL: "Mutation detection by ligation to complete n-mer DNA arrays.", GENOME RESEARCH. UNITED STATES NOV 1998, vol. 8, no. 11, November 1998 (1998-11-01), pages 1142 - 1153, XP002130857, ISSN: 1088-9051 * |
| HIRSCHHORN JOEL N ET AL: "SBE-TAGS: An array-based method for efficient single-nucleotide polymorphism genotyping", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 97, no. 22, 24 October 2000 (2000-10-24), pages 12164 - 12169, XP002158215, ISSN: 0027-8424 * |
| SHOEMAKER D D ET AL: "Quantitative phenotypic analysis of yeast deletion mutants using a highly parallel molecular bar-coding strategy.", NATURE GENETICS. UNITED STATES DEC 1996, vol. 14, no. 4, December 1996 (1996-12-01), pages 450 - 456, XP002043431, ISSN: 1061-4036 * |
Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7226734B2 (en) | 1998-06-24 | 2007-06-05 | Illumina, Inc. | Multiplex decoding of array sensors with microspheres |
| US9399795B2 (en) | 1998-06-24 | 2016-07-26 | Illumina, Inc. | Multiplex decoding of array sensors with microspheres |
| US7033754B2 (en) | 1998-06-24 | 2006-04-25 | Illumina, Inc. | Decoding of array sensors with microspheres |
| US7060431B2 (en) | 1998-06-24 | 2006-06-13 | Illumina, Inc. | Method of making and decoding of array sensors with microspheres |
| US7455971B2 (en) | 1998-06-24 | 2008-11-25 | Illumina, Inc. | Multiplex decoding of array sensors with microspheres |
| US7244559B2 (en) | 1999-09-16 | 2007-07-17 | 454 Life Sciences Corporation | Method of sequencing a nucleic acid |
| US7264929B2 (en) | 1999-09-16 | 2007-09-04 | 454 Life Sciences Corporation | Method of sequencing a nucleic acid |
| US7335762B2 (en) | 1999-09-16 | 2008-02-26 | 454 Life Sciences Corporation | Apparatus and method for sequencing a nucleic acid |
| US7211390B2 (en) | 1999-09-16 | 2007-05-01 | 454 Life Sciences Corporation | Method of sequencing a nucleic acid |
| US6902921B2 (en) | 2001-10-30 | 2005-06-07 | 454 Corporation | Sulfurylase-luciferase fusion proteins and thermostable sulfurylase |
| US6956114B2 (en) | 2001-10-30 | 2005-10-18 | '454 Corporation | Sulfurylase-luciferase fusion proteins and thermostable sulfurylase |
| US7323305B2 (en) | 2003-01-29 | 2008-01-29 | 454 Life Sciences Corporation | Methods of amplifying and sequencing nucleic acids |
| US7575865B2 (en) | 2003-01-29 | 2009-08-18 | 454 Life Sciences Corporation | Methods of amplifying and sequencing nucleic acids |
| US12442038B2 (en) | 2024-09-27 | 2025-10-14 | The Johns Hopkins University | Methods and materials for assessing nucleic acids |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002016649A2 (en) | 2002-02-28 |
| AU2001288393A1 (en) | 2002-03-04 |
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