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WO2002012348A3 - Isolation de particules de glucane et utilisations associees - Google Patents

Isolation de particules de glucane et utilisations associees Download PDF

Info

Publication number
WO2002012348A3
WO2002012348A3 PCT/EP2001/008851 EP0108851W WO0212348A3 WO 2002012348 A3 WO2002012348 A3 WO 2002012348A3 EP 0108851 W EP0108851 W EP 0108851W WO 0212348 A3 WO0212348 A3 WO 0212348A3
Authority
WO
WIPO (PCT)
Prior art keywords
isolation
glucan particles
glucan
particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2001/008851
Other languages
English (en)
Other versions
WO2002012348A2 (fr
Inventor
Martin Sauter
Stefan Freimund
Hans Dutler
Othmar Kaeppeli
Ahmad Al-Ghazawi
Eugen Schwarz
Lutz Thomas
Helmut Schoeberl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Priority to CA2418030A priority Critical patent/CA2418030C/fr
Priority to AU2001279796A priority patent/AU2001279796A1/en
Priority to US10/343,604 priority patent/US20040054166A1/en
Priority to EP01958040.6A priority patent/EP1414865B1/fr
Publication of WO2002012348A2 publication Critical patent/WO2002012348A2/fr
Publication of WO2002012348A3 publication Critical patent/WO2002012348A3/fr
Anticipated expiration legal-status Critical
Priority to US11/293,467 priority patent/US9187575B2/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/163—Sugars; Polysaccharides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/20—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
    • A23L29/269—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of microbial origin, e.g. xanthan or dextran
    • A23L29/271—Curdlan; beta-1-3 glucan; Polysaccharides produced by agrobacterium or alcaligenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/52—Sorbents specially adapted for preparative chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Materials Engineering (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Nutrition Science (AREA)
  • Dispersion Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PCT/EP2001/008851 2000-08-03 2001-07-31 Isolation de particules de glucane et utilisations associees Ceased WO2002012348A2 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CA2418030A CA2418030C (fr) 2000-08-03 2001-07-31 Isolation de particules de glucane et utilisations associees
AU2001279796A AU2001279796A1 (en) 2000-08-03 2001-07-31 Isolation of glucan particles and uses thereof
US10/343,604 US20040054166A1 (en) 2000-08-03 2001-07-31 Isolation of glucan particles and uses thereof
EP01958040.6A EP1414865B1 (fr) 2000-08-03 2001-07-31 Isolation de particules de glucane et utilisations associees
US11/293,467 US9187575B2 (en) 2000-08-03 2005-12-02 Isolation of glucan particles and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00116764.2 2000-08-03
EP00116764 2000-08-03

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US10343604 A-371-Of-International 2001-07-31
US11/293,467 Continuation US9187575B2 (en) 2000-08-03 2005-12-02 Isolation of glucan particles and uses thereof

Publications (2)

Publication Number Publication Date
WO2002012348A2 WO2002012348A2 (fr) 2002-02-14
WO2002012348A3 true WO2002012348A3 (fr) 2002-04-25

Family

ID=8169434

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/008851 Ceased WO2002012348A2 (fr) 2000-08-03 2001-07-31 Isolation de particules de glucane et utilisations associees

Country Status (5)

Country Link
US (2) US20040054166A1 (fr)
EP (1) EP1414865B1 (fr)
AU (1) AU2001279796A1 (fr)
CA (1) CA2418030C (fr)
WO (1) WO2002012348A2 (fr)

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DE60218299T2 (de) * 2001-04-27 2007-10-31 Ajinomoto Co., Inc. Eine Dispersion aus Beta-Glukan enthaltenden hochfeinen Partikel, ein entsprechender Herstellungsprozess und die Verwendung der Dispersion
ES2899590T3 (es) 2004-01-23 2022-03-14 Eden Research Plc Métodos de eliminación de nematodos que comprenden la aplicación de un componente terpénico
SI2338332T1 (sl) * 2004-05-20 2014-06-30 Eden Research Plc Votli delec glukana ali votli delec stene celice, ki enkapsulira komponento terpena
US7740861B2 (en) 2004-06-16 2010-06-22 University Of Massachusetts Drug delivery product and methods
ES2375995T3 (es) 2004-09-17 2012-03-08 University Of Massachusetts Composiciones y sus usos para deficiencias de enzima lisosomal.
EP1828372A1 (fr) * 2004-12-23 2007-09-05 DSMIP Assets B.V. Nouvelle mannoproteine integralement soluble dans le vin, et son application a la stabilisation du vin
US20080107784A1 (en) * 2004-12-23 2008-05-08 Peter Philip Lankhorst Process To Improve Activity Of Mannoprotein As Wine Stabiliser
CA2607004C (fr) 2005-05-05 2016-01-26 Sensient Flavors Inc. Production de beta-glucanes et de mannanes
AP2901A (en) 2005-11-30 2014-05-31 Eden Research Plc Compositions and methods comprising terpenes or terpene mixtures selected form thymol, eugenol, geraniol, citral, and L-carvone
WO2007063267A1 (fr) * 2005-11-30 2007-06-07 Eden Research Plc Compositions contenant des terpenes et procedes de production et d'utilisation de celles-ci
TW200900053A (en) * 2007-02-21 2009-01-01 Biotec Pharmacon Asa Medical uses of glucans
FR2921260B1 (fr) 2007-09-25 2012-08-24 Lesaffre & Cie Utilisation d'un nouvel agent naturel dans des compositions cosmetiques
US8389485B2 (en) 2007-10-29 2013-03-05 University Of Massachusetts Encapsulated nanoparticles for nucleic acid delivery
ITPD20080022A1 (it) 2008-01-23 2009-07-24 Enologica Vason Srl Metodo di produzione di un prodotto per la stabilizzazione tartarica del vino, prodotto per la stabilizzazione e procedimento di stabilizzazione mediante detto prodotto.
US8815818B2 (en) 2008-07-18 2014-08-26 Rxi Pharmaceuticals Corporation Phagocytic cell delivery of RNAI
US9493774B2 (en) 2009-01-05 2016-11-15 Rxi Pharmaceuticals Corporation Inhibition of PCSK9 through RNAi
BRPI0900639C1 (pt) * 2009-02-13 2011-12-20 Hebron Farmaceutica Pesquisa Desenvolvimento E Inovacao Tecnologica Ltda composição farmacêutica e uso desta para tratamento e/ou prevenção de doenças do trato respiratório
AU2011232365A1 (en) 2010-03-24 2012-10-25 Rxi Pharmaceuticals Corporation RNA interference in dermal and fibrotic indications
CN103200945B (zh) 2010-03-24 2016-07-06 雷克西制药公司 眼部症候中的rna干扰
WO2012024229A1 (fr) 2010-08-14 2012-02-23 University Of Massachusetts Particule de paroi cellulaire de levures pour administrer des nanoparticules ciblées sur le récepteur
US9603858B2 (en) 2010-11-29 2017-03-28 Raisio Nutrition Ltd. Compositions for preventing and treating an immune system disorder
GB201220940D0 (en) 2012-11-21 2013-01-02 Eden Research Plc Method P
CA2932753A1 (fr) 2013-12-04 2015-06-11 Rxi Pharmaceuticals Corporation Methodes de traitement de cicatrisation a l'aide d'oligonucleotides chimiquement modifies
WO2015168108A2 (fr) 2014-04-28 2015-11-05 Rxi Pharmaceuticals Corporation Procédés de traitement du cancer au moyen d'un acide nucléique deciblage de mdm2 ou mycn
JP2017514908A (ja) 2014-05-01 2017-06-08 アールエックスアイ ファーマシューティカルズ コーポレーション 核酸分子を利用する目の前部における障害の処置のための方法
EP3188799B1 (fr) 2014-09-05 2022-07-06 Phio Pharmaceuticals Corp. Méthodes de traitement de troubles cutanés et du vieillissement à l'aide d'acides nucléiques ciblant tyr ou mmp1
EP3234141A4 (fr) 2014-12-18 2018-06-20 Alnylam Pharmaceuticals, Inc. Composés reversir tm
JP6983752B2 (ja) 2015-07-06 2021-12-17 フィオ ファーマシューティカルズ コーポレーションPhio Pharmaceuticals Corp. スーパーオキシドディスムターゼ１（ｓｏｄ１）を標的とする核酸分子
WO2017007825A1 (fr) 2015-07-06 2017-01-12 Rxi Pharmaceuticals Corporation Procédés pour le traitement de troubles neurologiques à l'aide d'une petite molécule synergique et approche thérapeutique utilisant des acides nucléiques
JP2018531037A (ja) 2015-10-19 2018-10-25 アールエックスアイ ファーマシューティカルズ コーポレーション 長い非コードｒｎａを標的とする減少したサイズの自己送達型核酸化合物
EP3612152A4 (fr) 2017-04-19 2021-02-17 Phio Pharmaceuticals Corp. Administration topique de composés d'acide nucléique
CA3160657A1 (fr) 2019-11-08 2021-05-14 Phio Pharmaceuticals Corp. Oligonucleotides chimiquement modifies ciblant la proteine a bromodomaine 4 (brd4) pour immunotherapie
US11384160B1 (en) 2021-07-30 2022-07-12 Tissue repair ltd Method of making a beta glucan compound
US11572420B1 (en) 2021-07-30 2023-02-07 Tissue repair ltd Isolated biological polysaccharide compound, methods of use and methods of manufacture thereof
AR131799A1 (es) 2023-02-09 2025-04-30 Alnylam Pharmaceuticals Inc Moléculas de reversir y métodos para su uso
CN120857927A (zh) * 2023-04-14 2025-10-28 三菱商事生命科学株式会社 包含酵母提取物的外用组合物
CN118165137B (zh) * 2024-03-18 2024-09-10 克鲁维酵母科技(海南)有限公司 一种高纯度酵母β-葡聚糖的制备方法

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EP0416343A2 (fr) * 1989-09-04 1991-03-13 Consiglio Nazionale Delle Ricerche Procédé pour la préparation d'un produit contenant du glucane à partir de candida albicans BMM-12
WO1991007091A1 (fr) * 1989-11-09 1991-05-30 Donzis Byron A Extrait de levure insoluble
EP0440725A1 (fr) * 1988-10-28 1991-08-14 Alpha Beta Technology Additifs alimentaires a base de glucane.
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WO1994003500A1 (fr) * 1992-08-10 1994-02-17 Consiglio Nazionale Delle Ricerche Glucanes a activite immunostimulante

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EP0440725A1 (fr) * 1988-10-28 1991-08-14 Alpha Beta Technology Additifs alimentaires a base de glucane.
EP0416343A2 (fr) * 1989-09-04 1991-03-13 Consiglio Nazionale Delle Ricerche Procédé pour la préparation d'un produit contenant du glucane à partir de candida albicans BMM-12
WO1991007091A1 (fr) * 1989-11-09 1991-05-30 Donzis Byron A Extrait de levure insoluble
WO1992007064A1 (fr) * 1990-10-17 1992-04-30 Cpc International Inc. Traitement de dechets de levure et produit resultant dudit traitement
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Also Published As

Publication number Publication date
US20060134759A1 (en) 2006-06-22
EP1414865A2 (fr) 2004-05-06
WO2002012348A2 (fr) 2002-02-14
US20040054166A1 (en) 2004-03-18
US9187575B2 (en) 2015-11-17
CA2418030C (fr) 2010-10-26
CA2418030A1 (fr) 2002-02-14
EP1414865B1 (fr) 2014-04-09
AU2001279796A1 (en) 2002-02-18

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