WO2002011728A3 - Nouvelles compositions pharmaceutiques de medicaments contre la tuberculose et procede de fabrication - Google Patents

Nouvelles compositions pharmaceutiques de medicaments contre la tuberculose et procede de fabrication Download PDF

Info

Publication number: WO2002011728A3
Authority: WO; WIPO (PCT)
Prior art keywords: preparation; pharmaceutical compositions; novel pharmaceutical; tubercular drugs; tubercular
Prior art date: 2000-08-09
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Ceased

Application number

PCT/IN2001/000089

Other languages

English (en)

Other versions

WO2002011728A2 (fr

Inventor

Amarjit Singh

Rajesh Jain

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Panacea Biotec Ltd

Original Assignee

Panacea Biotec Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-08-09

Filing date

2001-04-10

Publication date

2002-04-25

2001-04-10 Priority to PL01355844A priority Critical patent/PL355844A1/xx

2001-04-10 Priority to US10/110,134 priority patent/US7195769B2/en

2001-04-10 Priority to AU56661/01A priority patent/AU778389C/en

2001-04-10 Priority to JP2002517064A priority patent/JP4098620B2/ja

2001-04-10 Priority to CA002386725A priority patent/CA2386725A1/fr

2001-04-10 Priority to IL14903001A priority patent/IL149030A0/xx

2001-04-10 Priority to HU0203451A priority patent/HUP0203451A3/hu

2001-04-10 Priority to EP01929986A priority patent/EP1307199A2/fr

2001-04-10 Priority to MXPA02003596A priority patent/MXPA02003596A/es

2001-04-10 Priority to NZ518216A priority patent/NZ518216A/en

2001-04-10 Application filed by Panacea Biotec Ltd filed Critical Panacea Biotec Ltd

2001-04-10 Priority to BR0107147-5A priority patent/BR0107147A/pt

2001-10-04 Priority to UA2002042825A priority patent/UA74164C2/uk

2002-02-14 Publication of WO2002011728A2 publication Critical patent/WO2002011728A2/fr

2002-04-04 Priority to NO20021599A priority patent/NO322503B1/no

2002-04-08 Priority to IL149030A priority patent/IL149030A/en

2002-04-11 Priority to BG106606A priority patent/BG65848B1/bg

2002-04-25 Publication of WO2002011728A3 publication Critical patent/WO2002011728A3/fr

2003-02-09 Anticipated expiration legal-status Critical

Status Ceased legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/12—Mucolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

Health & Medical Sciences (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pulmonology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

PCT/IN2001/000089 2000-08-09 2001-04-10 Nouvelles compositions pharmaceutiques de medicaments contre la tuberculose et procede de fabrication Ceased WO2002011728A2 (fr)

Priority Applications (15)

Application Number	Priority Date	Filing Date	Title
US10/110,134 US7195769B2 (en)	2000-08-09	2001-04-10	Pharmaceutical compositions of anti-tubercular drugs and process for their preparation
AU56661/01A AU778389C (en)	2000-08-09	2001-04-10	Novel pharmaceutical compositions of anti-tubercular drugs and process for their preparation
JP2002517064A JP4098620B2 (ja)	2000-08-09	2001-04-10	抗結核剤の新規な医薬組成物及びその調製方法
CA002386725A CA2386725A1 (fr)	2000-08-09	2001-04-10	Nouvelles compositions pharmaceutiques de medicaments contre la tuberculose et procede de fabrication
IL14903001A IL149030A0 (en)	2000-08-09	2001-04-10	Pharmaceutical compositions containing rifampicin, isoniazid or combinations thereof
HU0203451A HUP0203451A3 (en)	2000-08-09	2001-04-10	Pharmaceutical compositions of anti-tubercular drugs and process for their preparation
EP01929986A EP1307199A2 (fr)	2000-08-09	2001-04-10	Compositions pharmaceutiques de medicaments contre la tuberculose et procede de fabrication
NZ518216A NZ518216A (en)	2000-08-09	2001-04-10	Pharmaceutical compositions of anti-tubercular drugs and process for their preparation
MXPA02003596A MXPA02003596A (es)	2000-08-09	2001-04-10	Composiciones farmaceuticas novedosas de farmacos anti tubercular y procedimiento para su preparacion.
PL01355844A PL355844A1 (en)	2000-08-09	2001-04-10	Novel pharmaceutical compositions of anti-tubrcular drugs and process for their preparation
BR0107147-5A BR0107147A (pt)	2000-08-09	2001-04-10	Composições farmacêuticas de drogas anti-tuberculosas e processo para as suas preparações
UA2002042825A UA74164C2 (uk)	2000-08-09	2001-10-04	Фармацевтична композиція ліків проти туберкульозу і спосіб її одержання
NO20021599A NO322503B1 (no)	2000-08-09	2002-04-04	Orale farmasoytiske sammensetninger omfattende rifampicin og isoniazid
IL149030A IL149030A (en)	2000-08-09	2002-04-08	Pharmaceutical preparations containing rifampicin, azoniazid or mixtures thereof
BG106606A BG65848B1 (bg)	2000-08-09	2002-04-11	Фармацевтични състави на база противотурбекулозни лекарства и метод за тяхното получаване

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IN720DE2000		2000-08-09
IN720/DEL/2000		2000-08-09

Publications (2)

Publication Number	Publication Date
WO2002011728A2 WO2002011728A2 (fr)	2002-02-14
WO2002011728A3 true WO2002011728A3 (fr)	2002-04-25

Family

ID=11097078

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PCT/IN2001/000089 Ceased WO2002011728A2 (fr)	2000-08-09	2001-04-10	Nouvelles compositions pharmaceutiques de medicaments contre la tuberculose et procede de fabrication

Country Status (22)

Country	Link
US (1)	US7195769B2 (fr)
EP (1)	EP1307199A2 (fr)
JP (2)	JP4098620B2 (fr)
KR (1)	KR100620404B1 (fr)
CN (1)	CN1388758A (fr)
AU (1)	AU778389C (fr)
BG (1)	BG65848B1 (fr)
BR (1)	BR0107147A (fr)
CA (1)	CA2386725A1 (fr)
CZ (1)	CZ20021319A3 (fr)
HU (1)	HUP0203451A3 (fr)
IL (2)	IL149030A0 (fr)
MX (1)	MXPA02003596A (fr)
NO (1)	NO322503B1 (fr)
NZ (1)	NZ518216A (fr)
PL (1)	PL355844A1 (fr)
RU (1)	RU2240795C9 (fr)
TR (1)	TR200200966T1 (fr)
UA (1)	UA74164C2 (fr)
WO (1)	WO2002011728A2 (fr)
YU (1)	YU26102A (fr)
ZA (1)	ZA200202637B (fr)

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US7300670B2 (en) *	2002-04-03	2007-11-27	Unilab Pharmatech, Ltd.	Oral suspension formulation
US20050084455A1 (en) *	2003-10-16	2005-04-21	Council Of Scientific & Industrial Research	Inhalable biodegradable microparticles for target-specific drug delivery in tuberculosis and a process thereof
CN1319525C (zh) *	2004-09-16	2007-06-06	北京圣医耀科技发展有限责任公司	紫杉醇－海藻酸钠微球血管栓塞剂及其制备
HRP20080349T3 (hr) *	2004-11-18	2009-01-31	Bristol-Myers Squibb Company	Zrna premazana enteričkom smjesom koja sadrže iksabepilon
US20060134214A1 (en) *	2004-11-18	2006-06-22	Ismat Ullah	Enteric coated bead comprising epothilone or epothilone analog, and preparation and administration thereof
GB0516604D0 (en) *	2005-08-12	2005-09-21	Sandoz Ag	Rapidly dispersing/disintegrating compositions
CN1857220B (zh) *	2006-04-04	2010-10-06	济南康泉医药科技有限公司	一种抗结核病药物缓释剂
RU2327457C1 (ru) *	2007-06-26	2008-06-27	Автономная некоммерческая организация "Институт молекулярной диагностики" (АНО "ИнМоДи")	Лекарственное средство на основе рифабутина, препарат противомикробного действия, содержащий наночастицы, и способ его получения
US20090280173A1 (en) *	2008-05-09	2009-11-12	Ishwar Chauhan	Multilayer Omeprazole Tablets
WO2009137648A1 (fr) *	2008-05-09	2009-11-12	Aptapharma, Inc.	Pastilles multicouches inhibant la pompe à protons
US20100159001A1 (en) *	2008-12-19	2010-06-24	Cardinal John R	Extended-Release Pharmaceutical Formulations
US20100160363A1 (en) *	2008-12-19	2010-06-24	Aaipharma Services Corp.	Extended-release pharmaceutical formulations
KR101197277B1 (ko) *	2009-02-05	2012-11-05	(주) 벡스코아	경구용 결핵의 치료용 또는 예방용 고형 제형
WO2010093588A1 (fr) *	2009-02-10	2010-08-19	Celgene Corporation	Méthodes d'utilisation et compositions comprenant des modulateurs de pde4 pour traiter, prévenir, et gérer la tuberculose
AP2012006117A0 (en) *	2009-07-23	2012-02-29	Cadila Pharmaceuticals Ltd	Pharmaceutical composition of rifampicin.
AP2012006119A0 (en) *	2009-07-31	2012-02-29	Cadila Pharmaceuticals Ltd	Pharmaceutical composition of isoniazid.
WO2011126352A2 (fr) *	2010-04-07	2011-10-13	Товарищество С Ограниченной Ответственностью "Фармацевтическая Компания "Ромат"	Médicament contre la tuberculose sur la base d'un complexe d'inclusion de cyclodextrine et de rifampicine ainsi qu'un procédé de fabrication correspondant.
RU2423977C1 (ru) *	2010-04-20	2011-07-20	Открытое Акционерное Общество "Фармасинтез"	Противотуберкулезное лекарственное средство на основе 4-тиоуреидоиминометилпиридиния перхлората, способ его получения и способ лечения
RU2435611C1 (ru) *	2010-05-17	2011-12-10	Общество с ограниченной ответственностью "ФАРМХИМ" (ООО "ФАРМХИМ")	Способ получения полимерного комплекса
IT1400989B1 (it) *	2010-07-13	2013-07-05	Segix Italia S R L Ora Istituto Biochimico Naz Savio S R L	Forme di somministrazione orale a rilascio controllato di rifampicina per il trattamento di infezioni batteriche dell' apparato intestinale.
US8470365B2 (en)	2010-07-29	2013-06-25	Taiwan Biotech Co., Ltd.	Process for preparation of anti-tubercular combination and pharmaceutical composition prepared therefrom
TWI391134B (zh) *	2010-07-29	2013-04-01	Taiwan Biotech Co Ltd	製備抗結核病之組合的改良方法及由其製得之醫藥組合物
EA016410B1 (ru) *	2010-11-13	2012-04-30	Ооо "Нпк Наносистема"	Фармацевтическая композиция на основе наночастиц циклодекстрина, содержащих рифабутин, способ ее получения, способ лечения микобактериоза и геликобактерной инфекции (варианты)
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WO2013166114A1 (fr) *	2012-05-01	2013-11-07	Althera Life Sciences, Llc	Formulation de comprimé oral constituée d'une combinaison fixe d'atorvastatine et d'ézétimibe
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KR101301700B1 (ko) *	2012-11-14	2013-08-30	(주)비씨월드제약	용해도 및 안정성이 개선된 리팜피신을 포함하는 결핵 치료용 약학 조성물 및 이의 제조방법
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2001
- 2001-04-10 MX MXPA02003596A patent/MXPA02003596A/es active IP Right Grant
- 2001-04-10 KR KR1020027004329A patent/KR100620404B1/ko not_active Expired - Fee Related
- 2001-04-10 JP JP2002517064A patent/JP4098620B2/ja not_active Expired - Fee Related
- 2001-04-10 WO PCT/IN2001/000089 patent/WO2002011728A2/fr not_active Ceased
- 2001-04-10 AU AU56661/01A patent/AU778389C/en not_active Ceased
- 2001-04-10 IL IL14903001A patent/IL149030A0/xx active IP Right Grant
- 2001-04-10 PL PL01355844A patent/PL355844A1/xx not_active IP Right Cessation
- 2001-04-10 HU HU0203451A patent/HUP0203451A3/hu unknown
- 2001-04-10 YU YU26102A patent/YU26102A/sh unknown
- 2001-04-10 US US10/110,134 patent/US7195769B2/en not_active Expired - Fee Related
- 2001-04-10 BR BR0107147-5A patent/BR0107147A/pt not_active Application Discontinuation
- 2001-04-10 CZ CZ20021319A patent/CZ20021319A3/cs unknown
- 2001-04-10 TR TR2002/00966T patent/TR200200966T1/xx unknown
- 2001-04-10 RU RU2002115283/15A patent/RU2240795C9/ru not_active IP Right Cessation
- 2001-04-10 CA CA002386725A patent/CA2386725A1/fr not_active Abandoned
- 2001-04-10 CN CN01802338A patent/CN1388758A/zh active Pending
- 2001-04-10 EP EP01929986A patent/EP1307199A2/fr not_active Withdrawn
- 2001-04-10 NZ NZ518216A patent/NZ518216A/en unknown
- 2001-10-04 UA UA2002042825A patent/UA74164C2/uk unknown
2002
- 2002-04-04 ZA ZA200202637A patent/ZA200202637B/en unknown
- 2002-04-04 NO NO20021599A patent/NO322503B1/no not_active IP Right Cessation
- 2002-04-08 IL IL149030A patent/IL149030A/en not_active IP Right Cessation
- 2002-04-11 BG BG106606A patent/BG65848B1/bg unknown
2007
- 2007-11-14 JP JP2007295610A patent/JP2008056696A/ja not_active Withdrawn

Patent Citations (3)

* Cited by examiner, † Cited by third party
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GB2135879A (en) *	1983-03-07	1984-09-12	Ciba Geigy Ag	Pharmaceutical preparations with uniform elution properties
BE1010972A6 (fr) *	1996-10-09	1999-03-02	Lupin Lab Ltd	Composition pharmaceutique antituberculeuse et procede destine a produire ladite composition.
WO1999047123A1 (fr) *	1998-03-18	1999-09-23	Bristol-Myers Squibb Company	Composition pharmaceutique contenant une statine et de l'aspirine

Also Published As

Publication number	Publication date
HUP0203451A2 (hu)	2003-02-28
CN1388758A (zh)	2003-01-01
HUP0203451A3 (en)	2004-05-28
AU778389B2 (en)	2004-12-02
IL149030A0 (en)	2002-11-10
YU26102A (sh)	2004-12-31
BG65848B1 (bg)	2010-03-31
JP2008056696A (ja)	2008-03-13
NO20021599L (no)	2002-06-10
US20030072800A1 (en)	2003-04-17
US7195769B2 (en)	2007-03-27
EP1307199A2 (fr)	2003-05-07
IL149030A (en)	2007-06-17
JP2004505918A (ja)	2004-02-26
TR200200966T1 (tr)	2002-09-23
NO322503B1 (no)	2006-10-16
KR20020061602A (ko)	2002-07-24
JP4098620B2 (ja)	2008-06-11
ZA200202637B (en)	2003-08-20
RU2240795C9 (ru)	2005-09-27
CA2386725A1 (fr)	2002-02-14
MXPA02003596A (es)	2003-10-14
BG106606A (bg)	2002-12-29
NO20021599D0 (no)	2002-04-04
AU778389C (en)	2006-12-14
UA74164C2 (uk)	2005-11-15
RU2240795C2 (ru)	2004-11-27
RU2002115283A (ru)	2004-01-27
PL355844A1 (en)	2004-05-31
KR100620404B1 (ko)	2006-09-13
CZ20021319A3 (cs)	2002-08-14
NZ518216A (en)	2004-11-26
AU5666101A (en)	2002-02-18
WO2002011728A2 (fr)	2002-02-14
BR0107147A (pt)	2002-06-18

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AU2002216701A1 (en)	2002-05-27	Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs
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IL149618A0 (en)	2002-12-01	Pharmaceutical compositions comprising thiazolidinedione and process for preparation thereof
HUP0302319A3 (en)	2013-04-29	Pharmaceutical composition for oral administration of active ingredient
HUP0401537A3 (en)	2005-06-28	Thiohydantoins, process for their preparation, pharmaceutical compositions containing them and use thereof for preparation of pharmaceutical compositions
HUP0302358A3 (en)	2007-09-28	Piperazinedione compounds and use of them for producing pharmaceutical compositions
HUP0204110A3 (en)	2003-08-28	Amphiphilic prodrugs, process for preparation and use of pharmaceutical compositions containing them
HUP0302519A3 (en)	2008-10-28	Crystalline forms of atorvastatin, process for their preparation and pharmaceutical compositions containing them
PL367447A1 (en)	2005-02-21	Novel 2h-pyridazine-3-one derivatives, pharmaceutical compositions containing the same and a process for the preparation of the active ingredient
HUP0302130A3 (en)	2005-06-28	Combination pharmaceutical compositions and process for their preparation
NO20034709D0 (no)	2003-10-21	Fremgangsmåte for fremstilling av lav dose farmasöytisk sammensetning med jevn medikament fordeling og potens
HUP0202654A3 (en)	2003-11-28	Pharmaceutical compositions of fibrinolytic agent and process for preparation thereof
HUP0300370A3 (en)	2005-07-28	2-hydroxy-mutilin carbamate derivatives of antibacterial effect process for preparation and pharmaceutical compositions containing them
EP1181022A4 (fr)	2004-02-11	Compositions medicinales et leur procede de preparation
HUP0204563A3 (en)	2004-12-28	Process for preparation of 3,3-diarylpropylamine derivatives and their intermediates and their use for preparation of pharmaceutical compositions
AP2001002355A0 (en)	2001-12-31	Derivatives of purine their preparation process and pharmaceutical compositions containing them
IL161348A (en)	2010-11-30	Substituted 4- phenyl-4-[1h - imidazol-2-yl] piperidine derivatives and their use for the preparation of pharmaceutical compositions
HUP0303731A3 (en)	2006-02-28	Sulfonylguanidines and their use for preparation of pharmaceutical compositions
HUP0301317A3 (en)	2006-06-28	Use of neuroprotective 7-beta-hydroxysteroids for preparation of pharmaceutical compositions
HUP0300402A3 (en)	2005-07-28	Quinolinyl-piperidin-4-ylidene-methyl-benzamide derivatives for the treatment of pain and pharmaceutical compositions containing them
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IL166098A0 (en)	2006-01-15	3-guanindinocarbonyl-1-heteroaryl-indole derivatives preparation process their use as medicaments and pharmaceutical compositions comprising them

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