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WO2002008755A3 - Identifying antigen clusters for monitoring a global state of an immune system - Google Patents

Identifying antigen clusters for monitoring a global state of an immune system Download PDF

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Publication number
WO2002008755A3
WO2002008755A3 PCT/IL2001/000660 IL0100660W WO0208755A3 WO 2002008755 A3 WO2002008755 A3 WO 2002008755A3 IL 0100660 W IL0100660 W IL 0100660W WO 0208755 A3 WO0208755 A3 WO 0208755A3
Authority
WO
WIPO (PCT)
Prior art keywords
monitoring
immune system
global state
identifying antigen
antigen clusters
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IL2001/000660
Other languages
French (fr)
Other versions
WO2002008755A2 (en
Inventor
Irun R Cohen
Eytan Domany
Fransisco J Quintana
Guy Hed
Gad Getz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yeda Research and Development Co Ltd
Original Assignee
Yeda Research and Development Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to EP01961032A priority Critical patent/EP1368775A2/en
Priority to IL15383201A priority patent/IL153832A0/en
Priority to US10/332,241 priority patent/US20040014069A1/en
Priority to CA002418217A priority patent/CA2418217A1/en
Priority to AU2001282414A priority patent/AU2001282414A1/en
Application filed by Yeda Research and Development Co Ltd filed Critical Yeda Research and Development Co Ltd
Publication of WO2002008755A2 publication Critical patent/WO2002008755A2/en
Priority to IL153832A priority patent/IL153832A/en
Anticipated expiration legal-status Critical
Publication of WO2002008755A3 publication Critical patent/WO2002008755A3/en
Priority to US12/357,449 priority patent/US8010298B2/en
Priority to IL210570A priority patent/IL210570A/en
Priority to US13/207,486 priority patent/US8703654B2/en
Priority to US14/210,409 priority patent/US10082503B2/en
Priority to US16/123,385 priority patent/US20190004045A1/en
Priority to US16/748,001 priority patent/US11002735B2/en
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/30—Unsupervised data analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20—Supervised data analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Hematology (AREA)
  • Data Mining & Analysis (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Evolutionary Biology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioethics (AREA)
  • Software Systems (AREA)
  • Public Health (AREA)
  • Evolutionary Computation (AREA)
  • Epidemiology (AREA)
  • Databases & Information Systems (AREA)
  • Artificial Intelligence (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)

Abstract

Method, system and an article of manufacture for clustering and thereby identifying predefined antigens reactive with undetermined immunoglobulins of sera derived from patient subjects in need of diagnosis of disease or monitoring of treatment.
PCT/IL2001/000660 2000-07-24 2001-07-18 Identifying antigen clusters for monitoring a global state of an immune system Ceased WO2002008755A2 (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
EP01961032A EP1368775A2 (en) 2000-07-24 2001-07-18 Identifying antigen clusters for monitoring a global state of an immune system
IL15383201A IL153832A0 (en) 2000-07-24 2001-07-18 Identifying antigen clusters for monitoring a global state of an immune system
US10/332,241 US20040014069A1 (en) 2000-07-24 2001-07-18 Identifying antigen clusters for monitoring a global state of an immune system
CA002418217A CA2418217A1 (en) 2000-07-24 2001-07-18 Identifying antigen clusters for monitoring a global state of an immune system
AU2001282414A AU2001282414A1 (en) 2000-07-24 2001-07-18 Identifying antigen clusters for monitoring a global state of an immune system
IL153832A IL153832A (en) 2000-07-24 2003-01-07 Identifying antigen clusters for monitoring a global state of an immune system
US12/357,449 US8010298B2 (en) 2000-07-24 2009-01-22 Identifying antigen clusters for monitoring a global state of an immune system
IL210570A IL210570A (en) 2000-07-24 2011-01-11 Identifying antigen clusters for monitoring a global state of an immune system
US13/207,486 US8703654B2 (en) 2000-07-24 2011-08-11 Identifying antigen clusters for monitoring a global state of an immune system
US14/210,409 US10082503B2 (en) 2000-07-24 2014-03-13 Identifying antigen clusters for monitoring a global state of an immune system
US16/123,385 US20190004045A1 (en) 2000-07-24 2018-09-06 Identifying antigen clusters for monitoring a global state of an immune system
US16/748,001 US11002735B2 (en) 2000-07-24 2020-01-21 Identifying antigen clusters for monitoring a global state of an immune system

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL13746000A IL137460A0 (en) 2000-07-24 2000-07-24 Identifying antigen clusters for monitoring a global state of an immune system
IL137460 2000-07-24

Related Child Applications (3)

Application Number Title Priority Date Filing Date
US10/332,241 A-371-Of-International US20040014069A1 (en) 2000-07-24 2001-07-18 Identifying antigen clusters for monitoring a global state of an immune system
US10332241 A-371-Of-International 2001-07-18
US12/357,449 Continuation US8010298B2 (en) 2000-07-24 2009-01-22 Identifying antigen clusters for monitoring a global state of an immune system

Publications (2)

Publication Number Publication Date
WO2002008755A2 WO2002008755A2 (en) 2002-01-31
WO2002008755A3 true WO2002008755A3 (en) 2003-09-12

Family

ID=11074431

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2001/000660 Ceased WO2002008755A2 (en) 2000-07-24 2001-07-18 Identifying antigen clusters for monitoring a global state of an immune system

Country Status (6)

Country Link
US (6) US20040014069A1 (en)
EP (1) EP1368775A2 (en)
AU (1) AU2001282414A1 (en)
CA (1) CA2418217A1 (en)
IL (3) IL137460A0 (en)
WO (1) WO2002008755A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112259219B (en) * 2020-09-30 2024-02-02 吾征智能技术(北京)有限公司 System, equipment and storage medium for predicting diseases based on upper gastrointestinal bleeding

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IL137460A0 (en) 2000-07-24 2001-07-24 Yeda Res & Dev Identifying antigen clusters for monitoring a global state of an immune system
US8460243B2 (en) * 2003-06-10 2013-06-11 Abbott Diabetes Care Inc. Glucose measuring module and insulin pump combination
US7722536B2 (en) * 2003-07-15 2010-05-25 Abbott Diabetes Care Inc. Glucose measuring device integrated into a holster for a personal area network device
US20050260770A1 (en) * 2004-04-01 2005-11-24 Cohen Irun R Antigen array and diagnostic uses thereof
US20060010098A1 (en) 2004-06-04 2006-01-12 Goodnow Timothy T Diabetes care host-client architecture and data management system
US9267945B2 (en) * 2008-11-12 2016-02-23 Yeda Research And Development Co. Ltd. Diagnosis of multiple sclerosis
WO2011041531A1 (en) 2009-09-30 2011-04-07 Abbott Diabetes Care Inc. Interconnect for on-body analyte monitoring device
ES2560809T3 (en) 2010-02-12 2016-02-22 Yeda Research And Development Co. Ltd. Diagnosis of systemic lupus erythematosus
US20140011879A1 (en) * 2010-09-29 2014-01-09 Janssen Biotech, Inc. Serum markers for identification of cutaneous systemic sclerosis subjects
US10136845B2 (en) 2011-02-28 2018-11-27 Abbott Diabetes Care Inc. Devices, systems, and methods associated with analyte monitoring devices and devices incorporating the same
US8652999B1 (en) 2012-07-24 2014-02-18 Dow Agrosciences, Llc. Herbicidal compositions comprising 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylic acid or a derivative thereof and a sulfonylaminocarbonyltriazolinone
EP3090263A4 (en) 2013-12-31 2017-08-23 Yeda Research and Development Co., Ltd. Methods for assaying immunological competence
WO2015101988A1 (en) 2013-12-31 2015-07-09 Yeda Research And Development Co. Ltd. Diagnosis of systemic lupus erythematosus using oligonucleotides antigens
CN107533048A (en) 2015-02-05 2018-01-02 美国免疫阵列公司 For diagnosing the method and composition of brain damage or neurodegeneration
WO2016139659A1 (en) 2015-03-01 2016-09-09 Immunarray Ltd. Diagnosis of systemic lupus erythematosus using protein, peptide and oligonucleotide antigens
WO2019177152A1 (en) * 2018-03-16 2019-09-19 Ｋｏｔａｉバイオテクノロジーズ株式会社 Effective clustering of immunological entities
JP6500144B1 (en) * 2018-03-28 2019-04-10 Ｋｏｔａｉバイオテクノロジーズ株式会社 Efficient clustering of immune entities
JP7641912B2 (en) 2019-04-19 2025-03-07 シナーキン・ファーマ・ベスローテン・フエンノートシャップ Fusion proteins containing IL13
MY208431A (en) 2019-06-03 2025-05-08 Aihol Corp Hyaluronan conjugates and uses thereof
WO2024151949A1 (en) * 2023-01-13 2024-07-18 The Broad Institute, Inc. Methods for generating dual targeting biotherapeutics that specifically bind proteins present in a surface proteome

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112259219B (en) * 2020-09-30 2024-02-02 吾征智能技术(北京)有限公司 System, equipment and storage medium for predicting diseases based on upper gastrointestinal bleeding

Also Published As

Publication number Publication date
IL153832A (en) 2011-02-28
US11002735B2 (en) 2021-05-11
IL210570A0 (en) 2011-03-31
IL210570A (en) 2012-10-31
IL137460A0 (en) 2001-07-24
AU2001282414A1 (en) 2002-02-05
US20090258790A1 (en) 2009-10-15
US20110301065A1 (en) 2011-12-08
US10082503B2 (en) 2018-09-25
US20140200159A1 (en) 2014-07-17
US8010298B2 (en) 2011-08-30
US20190004045A1 (en) 2019-01-03
WO2002008755A2 (en) 2002-01-31
CA2418217A1 (en) 2002-01-31
EP1368775A2 (en) 2003-12-10
US20040014069A1 (en) 2004-01-22
US20200225223A1 (en) 2020-07-16
US8703654B2 (en) 2014-04-22

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