[go: up one dir, main page]

WO2002000142A3 - Disque intervertebral - Google Patents

Disque intervertebral Download PDF

Info

Publication number
WO2002000142A3
WO2002000142A3 PCT/CA2001/000972 CA0100972W WO0200142A3 WO 2002000142 A3 WO2002000142 A3 WO 2002000142A3 CA 0100972 W CA0100972 W CA 0100972W WO 0200142 A3 WO0200142 A3 WO 0200142A3
Authority
WO
WIPO (PCT)
Prior art keywords
intervertebral disc
engineered biological
constructs
biological material
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CA2001/000972
Other languages
English (en)
Other versions
WO2002000142A2 (fr
Inventor
Rita Kandel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mt Sinai Hospital
Original Assignee
Mt Sinai Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mt Sinai Hospital filed Critical Mt Sinai Hospital
Priority to CA2413353A priority Critical patent/CA2413353C/fr
Priority to DE60141964T priority patent/DE60141964D1/de
Priority to US10/312,655 priority patent/US20040083001A1/en
Priority to EP01949164A priority patent/EP1297107B1/fr
Priority to AT01949164T priority patent/ATE466072T1/de
Priority to AU2001270408A priority patent/AU2001270408A1/en
Publication of WO2002000142A2 publication Critical patent/WO2002000142A2/fr
Publication of WO2002000142A3 publication Critical patent/WO2002000142A3/fr
Anticipated expiration legal-status Critical
Priority to US11/858,716 priority patent/US8163554B2/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843—Connective tissue
    • A61L27/3852—Cartilage, e.g. meniscus
    • A61L27/3856—Intervertebral discs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3612—Cartilage, synovial fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3633—Extracellular matrix [ECM]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3817—Cartilage-forming cells, e.g. pre-chondrocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30667—Features concerning an interaction with the environment or a particular use of the prosthesis
    • A61F2002/30677—Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442—Intervertebral or spinal discs, e.g. resilient
    • A61F2002/4435—Support means or repair of the natural disc wall, i.e. annulus, e.g. using plates, membranes or meshes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442—Intervertebral or spinal discs, e.g. resilient
    • A61F2002/4445—Means for culturing intervertebral disc tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442—Intervertebral or spinal discs, e.g. resilient
    • A61F2002/445—Intervertebral disc tissue harvest sites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00359—Bone or bony tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/38—Materials or treatment for tissue regeneration for reconstruction of the spine, vertebrae or intervertebral discs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Biophysics (AREA)
  • Vascular Medicine (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Thermistors And Varistors (AREA)

Abstract

L'invention concerne un matériau biologique travaillé comprenant des tissus d'un disque intervertébral ou enrichi par ceux-ci; des tissus dérivés d'un matériau biologique travaillé, des constructions comprenant un ou plusieurs tissus issus d'un matériau biologique travaillé, ainsi que des procédés de préparation et d'utilisation des matériaux biologiques travaillés et des constructions.
PCT/CA2001/000972 2000-06-29 2001-06-29 Disque intervertebral Ceased WO2002000142A2 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
CA2413353A CA2413353C (fr) 2000-06-29 2001-06-29 Disque intervertebral
DE60141964T DE60141964D1 (de) 2000-06-29 2001-06-29 Bandscheibe
US10/312,655 US20040083001A1 (en) 2000-06-29 2001-06-29 Intervertebral disc
EP01949164A EP1297107B1 (fr) 2000-06-29 2001-06-29 Disque intervertebral
AT01949164T ATE466072T1 (de) 2000-06-29 2001-06-29 Bandscheibe
AU2001270408A AU2001270408A1 (en) 2000-06-29 2001-06-29 Intervertebral disc
US11/858,716 US8163554B2 (en) 2000-06-29 2007-09-20 Intervertebral disc

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21502200P 2000-06-29 2000-06-29
US60/215,022 2000-06-29

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US10312655 A-371-Of-International 2001-06-29
US11/858,716 Continuation US8163554B2 (en) 2000-06-29 2007-09-20 Intervertebral disc

Publications (2)

Publication Number Publication Date
WO2002000142A2 WO2002000142A2 (fr) 2002-01-03
WO2002000142A3 true WO2002000142A3 (fr) 2002-08-08

Family

ID=22801316

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA2001/000972 Ceased WO2002000142A2 (fr) 2000-06-29 2001-06-29 Disque intervertebral

Country Status (7)

Country Link
US (2) US20040083001A1 (fr)
EP (1) EP1297107B1 (fr)
AT (1) ATE466072T1 (fr)
AU (1) AU2001270408A1 (fr)
CA (1) CA2413353C (fr)
DE (1) DE60141964D1 (fr)
WO (1) WO2002000142A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7556649B2 (en) 2000-04-07 2009-07-07 Zimmer Orthobiologics, Inc. Methods and compositions for treating intervertebral disc degeneration

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2278648T3 (es) 1999-12-06 2007-08-16 Warsaw Orthopedic, Inc. Dispositivo para tratar un disco intervertebral.
US6805695B2 (en) 2000-04-04 2004-10-19 Spinalabs, Llc Devices and methods for annular repair of intervertebral discs
WO2002000142A2 (fr) * 2000-06-29 2002-01-03 Mount Sinai Hospital Disque intervertebral
WO2003066120A1 (fr) * 2002-02-04 2003-08-14 Ferree Bret A Traitement d'une maladie degenerative du disque par transplantation d'un disque allogreffe
US7744651B2 (en) * 2002-09-18 2010-06-29 Warsaw Orthopedic, Inc Compositions and methods for treating intervertebral discs with collagen-based materials
US20040054414A1 (en) 2002-09-18 2004-03-18 Trieu Hai H. Collagen-based materials and methods for augmenting intervertebral discs
CN100394989C (zh) 2002-11-15 2008-06-18 华沙整形外科股份有限公司 包含微粒状基于胶原材料的组合物的制药应用和包含所述组合物的滑膜关节
US20040186471A1 (en) * 2002-12-07 2004-09-23 Sdgi Holdings, Inc. Method and apparatus for intervertebral disc expansion
AU2004208821B2 (en) * 2003-01-31 2009-01-15 Zimmer Orthobiologics Inc. Hydrogel compositions comprising nucleus pulposus tissue
EP1610740A4 (fr) * 2003-04-04 2009-04-08 Theken Disc Llc Prothese de disque artificiel
US8697139B2 (en) 2004-09-21 2014-04-15 Frank M. Phillips Method of intervertebral disc treatment using articular chondrocyte cells
WO2006053016A2 (fr) * 2004-11-10 2006-05-18 Wayne Vicker Procede et systeme d'extraction automatisee rapide et autres processus, mettant en oeuvre une temperature et une pression regulables
JP4907908B2 (ja) * 2005-06-29 2012-04-04 ルネサスエレクトロニクス株式会社 駆動回路及び表示装置
US20070093905A1 (en) * 2005-10-21 2007-04-26 O'neil Michael J Degenerative disc regeneration techniques
US20070213717A1 (en) * 2006-02-14 2007-09-13 Sdgi Holdings, Inc. Biological fusion in the vertebral column
US20070227547A1 (en) * 2006-02-14 2007-10-04 Sdgi Holdings, Inc. Treatment of the vertebral column
US7520888B2 (en) * 2006-02-14 2009-04-21 Warsaw Orthopedic, Inc. Treatment of the vertebral column
US20070213718A1 (en) * 2006-02-14 2007-09-13 Sdgi Holdings, Inc. Treatment of the vertebral column
US8399619B2 (en) * 2006-06-30 2013-03-19 Warsaw Orthopedic, Inc. Injectable collagen material
US8118779B2 (en) * 2006-06-30 2012-02-21 Warsaw Orthopedic, Inc. Collagen delivery device
US20080004703A1 (en) * 2006-06-30 2008-01-03 Warsaw Orthopedic, Inc. Method of treating a patient using a collagen material
US20080004431A1 (en) * 2006-06-30 2008-01-03 Warsaw Orthopedic Inc Method of manufacturing an injectable collagen material
WO2008098366A1 (fr) * 2007-02-14 2008-08-21 Mount Sinai Hospital Echafaudage fibreux pour une utilisation dans l'élaboration de tissus mous
US8109444B2 (en) * 2007-09-12 2012-02-07 Devicefidelity, Inc. Selectively switching antennas of transaction cards
TWI453280B (zh) * 2009-02-26 2014-09-21 Win Ping Deng 治療劑篩檢方法以及椎間盤培養方法
US9044335B2 (en) * 2009-05-05 2015-06-02 Cornell University Composite tissue-engineered intervertebral disc with self-assembled annular alignment
WO2015003251A1 (fr) * 2013-07-12 2015-01-15 Rita Kandel Implant de disque intervertébral
US11285177B2 (en) 2018-01-03 2022-03-29 Globus Medical, Inc. Allografts containing viable cells and methods thereof
CN114343929B (zh) * 2022-01-13 2025-06-03 苏州大学 利用近场直写3d打印技术制备微型仿生椎间盘支架的方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6080579A (en) * 1997-11-26 2000-06-27 Charlotte-Mecklenburg Hospital Authority Method for producing human intervertebral disc cells

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5326357A (en) * 1992-03-18 1994-07-05 Mount Sinai Hospital Corporation Reconstituted cartridge tissue
US20020111695A1 (en) * 1995-11-06 2002-08-15 Mount Sinai Hospital Corporation Reconstituted mineralized cartilage tissue
CA2236807A1 (fr) * 1995-11-06 1997-05-15 Rita Kandel Tissu cartilagineux reconstitue et mineralise
WO1997045147A1 (fr) 1996-05-28 1997-12-04 1218122 Ontario Inc. Biomateriau resorbable pour implant forme de particules de phosphate de calcium condensees
US5964807A (en) * 1996-08-08 1999-10-12 Trustees Of The University Of Pennsylvania Compositions and methods for intervertebral disc reformation
US20010006948A1 (en) * 1998-11-25 2001-07-05 James D. Kang Gene transfer to intervertebral disc cells
CA2285161A1 (fr) 1999-10-06 2001-04-06 1218122 Ontario Inc. Tissu de ligament cultive in vitro et methode pour sa production
JP2003512110A (ja) * 1999-10-15 2003-04-02 マウント・シナイ・ホスピタル 組織形成のための合成基材
WO2002000142A2 (fr) * 2000-06-29 2002-01-03 Mount Sinai Hospital Disque intervertebral
US6902932B2 (en) * 2001-11-16 2005-06-07 Tissue Regeneration, Inc. Helically organized silk fibroin fiber bundles for matrices in tissue engineering
AU2003249366A1 (en) * 2002-06-24 2004-01-06 Tufts University Silk biomaterials and methods of use thereof
WO2008098366A1 (fr) 2007-02-14 2008-08-21 Mount Sinai Hospital Echafaudage fibreux pour une utilisation dans l'élaboration de tissus mous

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6080579A (en) * 1997-11-26 2000-06-27 Charlotte-Mecklenburg Hospital Authority Method for producing human intervertebral disc cells

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
MIZUNO H ET AL: "Tissue engineering of a composite intervertebral disc.", TISSUE ENGINEERING, vol. 6, no. 6, December 2000 (2000-12-01), Third Biennial Meeting of the Tissue Engineering Society;Orlando, Florida, USA; November 30-December 03, 2000, pages 666, XP002195743, ISSN: 1076-3279 *
OKUMA MASAHIKO ET AL: "Reinsertion of stimulated nucleus pulposus cells retards intervertebral disc degeneration: An in vitro and in vivo experimental study.", JOURNAL OF ORTHOPAEDIC RESEARCH, vol. 18, no. 6, November 2000 (2000-11-01), pages 988 - 997, XP001064826, ISSN: 0736-0266 *
REINECKE J A ET AL: "In vitro transfer of genes into spinal tissues.", ZEITSCHRIFT FUER ORTHOPAEDIE UND IHRE GRENZGEBIETE, vol. 135, no. 5, 1997, pages 412 - 416, XP001064896, ISSN: 0044-3220 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7556649B2 (en) 2000-04-07 2009-07-07 Zimmer Orthobiologics, Inc. Methods and compositions for treating intervertebral disc degeneration

Also Published As

Publication number Publication date
DE60141964D1 (de) 2010-06-10
US20080119936A1 (en) 2008-05-22
CA2413353A1 (fr) 2002-01-03
EP1297107A2 (fr) 2003-04-02
CA2413353C (fr) 2013-01-29
US20040083001A1 (en) 2004-04-29
AU2001270408A1 (en) 2002-01-08
WO2002000142A2 (fr) 2002-01-03
US8163554B2 (en) 2012-04-24
ATE466072T1 (de) 2010-05-15
EP1297107B1 (fr) 2010-04-28

Similar Documents

Publication Publication Date Title
WO2002000142A3 (fr) Disque intervertebral
WO2004032713A3 (fr) Scellants pour la peau et autres tissus
WO2004041075A3 (fr) Systeme semi-biologique de remplacement de disque intervertebral
AU2002340807A1 (en) Method for the devitalisation of natural organs and/or for the preparation of extracellular matrices for tissue engineering
AU2001284857A1 (en) Surgical instrumentation and method for treatment of the spine
AU2001255662A1 (en) Miniaturized surgical forceps and methods of making the same
AU2002366083A1 (en) Matrix for the production of tissue engineered ligaments, tendons and other tissue
WO2001083755A3 (fr) Anticorps humains anti-cd40, et leurs procedes de production et d'utilisation
WO2000074741A3 (fr) Produit de synthese biologique pour articulation
WO2002096272A3 (fr) Element vaso-occlusif implantable absorbable
ATE555798T1 (de) Gewebeimplantate und verfahren zur ihrer herstellung und verwendung
AU2001282926A1 (en) Spinal implants, insertion instruments, and methods of use
AU2002323457A1 (en) Implant for partial disc and cancellous bone replacement
DE60129007D1 (de) Vermehrung des weich- sowie des knochengewebes anhand von aus muskeln stammenden vorläuferzellen, sowie damit verbundene zusammensetzungen und behandlungsformen
AU1515901A (en) Implant consisting of bone material
AU2002361860A1 (en) Calcium phosphate bone replacement materials and methods of use thereof
WO2001057082A3 (fr) Extraction de facteurs de croissance a partir du tissu
AU2002351277A1 (en) Biodegradable, porous structures useful for growing living tissue, and methods of manufacture
AU2001245461A1 (en) Product and method for biological anchoring of connective tissue to bone
WO2006081435A3 (fr) Procede d'obtention de materiau cellulaire derive de sang de cordon facilement utilisable, et compositions correspondantes
WO2006093857A3 (fr) Procede de production d'une substance cellulaire facilement disponible derivee du sang peripherique et composition de cette substance
AU2001273475A1 (en) Coagulator and spinal disk surgery
WO2001091700A8 (fr) Composition et procede destine a ameliorer l'elasticite des tissus
AU2002353078A1 (en) Tissue graft compositions and methods for producing same
AU2001234831A1 (en) Magnetoliposome composition for targeted treatment of biological tissue and associated methods

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

WWE Wipo information: entry into national phase

Ref document number: 2413353

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2001949164

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2001949164

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWE Wipo information: entry into national phase

Ref document number: 10312655

Country of ref document: US

NENP Non-entry into the national phase

Ref country code: JP