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WO2002099094A3 - Human serine/threonine protein kinase-like enzyme - Google Patents

Human serine/threonine protein kinase-like enzyme Download PDF

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Publication number
WO2002099094A3
WO2002099094A3 PCT/EP2002/006137 EP0206137W WO02099094A3 WO 2002099094 A3 WO2002099094 A3 WO 2002099094A3 EP 0206137 W EP0206137 W EP 0206137W WO 02099094 A3 WO02099094 A3 WO 02099094A3
Authority
WO
WIPO (PCT)
Prior art keywords
protein kinase
enzyme
threonine protein
human serine
reagents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2002/006137
Other languages
French (fr)
Other versions
WO2002099094A2 (en
Inventor
Alex Smolyar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Priority to AU2002312976A priority Critical patent/AU2002312976A1/en
Publication of WO2002099094A2 publication Critical patent/WO2002099094A2/en
Publication of WO2002099094A3 publication Critical patent/WO2002099094A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

Reagents that regulate human serine/threonine protein kinase-like enzyme and reagents which bind to human serine/threonine protein kinase-like enzyme gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, cancer, cardiovascular disorders, CNS, COPD, obesity, genito-urinary disorders and diabetes.
PCT/EP2002/006137 2001-06-07 2002-06-04 Human serine/threonine protein kinase-like enzyme Ceased WO2002099094A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002312976A AU2002312976A1 (en) 2001-06-07 2002-06-04 Human serine/threonine protein kinase-like enzyme

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29616501P 2001-06-07 2001-06-07
US60/296,165 2001-06-07

Publications (2)

Publication Number Publication Date
WO2002099094A2 WO2002099094A2 (en) 2002-12-12
WO2002099094A3 true WO2002099094A3 (en) 2003-03-20

Family

ID=23140884

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/006137 Ceased WO2002099094A2 (en) 2001-06-07 2002-06-04 Human serine/threonine protein kinase-like enzyme

Country Status (2)

Country Link
AU (1) AU2002312976A1 (en)
WO (1) WO2002099094A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998001756A1 (en) * 1996-07-09 1998-01-15 Washington University DNA SEQUENCES ENCODING HUMAN TcAK1 KINASE
WO2000073469A2 (en) * 1999-05-28 2000-12-07 Sugen, Inc. Protein kinases

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998001756A1 (en) * 1996-07-09 1998-01-15 Washington University DNA SEQUENCES ENCODING HUMAN TcAK1 KINASE
WO2000073469A2 (en) * 1999-05-28 2000-12-07 Sugen, Inc. Protein kinases

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 10 August 1999 (1999-08-10), WAGGONER S.N. ET AL.: "Homo sapiens serine/threonine protein kinase Kp78 splice variant CTAK75a mRNA, complete cds", XP002224047, retrieved from EBI Database accession no. AF159295 *
DATABASE EMBL [online] 14 March 2002 (2002-03-14), "Homo sapiens, clone MGC:29880 IMAGE:5138958, mRNA, complete cds", XP002224049, retrieved from EBI Database accession no. BC024773 *
DATABASE EMBL [online] 24 January 1992 (1992-01-24), MAHESHWARI K.K. ET AL.: "Human protein p78 mRNA, complete cds", XP002224045, retrieved from EBI Database accession no. M80359 *
DATABASE EMBL [online] 24 January 2001 (2001-01-24), "6 2269460F1 NIH_MGC_84 Homo sapiens cDNA clone IMAGE:4357671 5', mRNA sequence", XP002224048, retrieved from EBI Database accession no. BF968374 *
DATABASE EMBL [online] 28 April 1998 (1998-04-28), PENG C.Y. ET AL.: "Homo sapiens Cdc25C associated protein kinase C-TAK1 mRNA, complete cds", XP002224046, retrieved from EBI Database accession no. U64205 *
DATABASE EMBL [online] 4 February 2002 (2002-02-04), "Homo sapiens MAP/microtubule affinity-regulating kinase 3 long isoform (MARK3) mRNA, complete cds; alternatively spliced", XP002224050, retrieved from EBI Database accession no. AF465413 *

Also Published As

Publication number Publication date
WO2002099094A2 (en) 2002-12-12
AU2002312976A1 (en) 2002-12-16

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