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WO2002092818A3 - Sequence du genome streptococcus agalactiae et ses utilisations - Google Patents

Sequence du genome streptococcus agalactiae et ses utilisations Download PDF

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Publication number
WO2002092818A3
WO2002092818A3 PCT/IB2002/003059 IB0203059W WO02092818A3 WO 2002092818 A3 WO2002092818 A3 WO 2002092818A3 IB 0203059 W IB0203059 W IB 0203059W WO 02092818 A3 WO02092818 A3 WO 02092818A3
Authority
WO
WIPO (PCT)
Prior art keywords
genome sequence
therapeutic targets
streptococcus agalactiae
diagnostic tools
identifying therapeutic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2002/003059
Other languages
English (en)
Other versions
WO2002092818A8 (fr
WO2002092818A2 (fr
Inventor
Philippe Glaser
Christophe Rusniok
Fabien Chevalier
Lionel Frangeul
Lila Lalioui
Mohamed Zouine
Elisabeth Couve
Carmen Buchrieser
Claire Poyart
Patrick Trieu-Cuot
Frank Kunst
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Institut Pasteur
Original Assignee
Centre National de la Recherche Scientifique CNRS
Institut Pasteur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS, Institut Pasteur filed Critical Centre National de la Recherche Scientifique CNRS
Priority to AU2002319867A priority Critical patent/AU2002319867A1/en
Publication of WO2002092818A2 publication Critical patent/WO2002092818A2/fr
Publication of WO2002092818A3 publication Critical patent/WO2002092818A3/fr
Anticipated expiration legal-status Critical
Publication of WO2002092818A8 publication Critical patent/WO2002092818A8/fr
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention a pour objet la séquence génomique et des séquences nucléotidiques codant pour des polypeptides de Streptococcus agalactiae, tels que des polypeptides d'enveloppe cellulaire, ou des polypeptides sécrétés ou spécifiques, ou impliqués dans le métabolisme et dans le processus de réplication, ainsi que des vecteurs ou cellules incluant lesdites séquences. L'invention porte également sur leur application au développement de vaccins, d'outils de diagnostic, de puces à ADN et à l'identification de cibles thérapeutiques.
PCT/IB2002/003059 2001-04-26 2002-04-26 Sequence du genome streptococcus agalactiae et ses utilisations Ceased WO2002092818A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002319867A AU2002319867A1 (en) 2001-04-26 2002-04-26 Streptococcus agalactiae genome sequence, use for developing vaccines, diagnostic tools, and for identifying therapeutic targets

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0105642A FR2824074A1 (fr) 2001-04-26 2001-04-26 Sequence du genome streptococcus agalactiae, application au developpement de vaccins, d'outils de diagnostic, et a l'identification de cibles therapeutiques
FR2001/05642 2001-04-26

Publications (3)

Publication Number Publication Date
WO2002092818A2 WO2002092818A2 (fr) 2002-11-21
WO2002092818A3 true WO2002092818A3 (fr) 2003-08-28
WO2002092818A8 WO2002092818A8 (fr) 2004-03-04

Family

ID=8862732

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2002/003059 Ceased WO2002092818A2 (fr) 2001-04-26 2002-04-26 Sequence du genome streptococcus agalactiae et ses utilisations

Country Status (3)

Country Link
AU (1) AU2002319867A1 (fr)
FR (1) FR2824074A1 (fr)
WO (1) WO2002092818A2 (fr)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6890539B2 (en) 1998-12-22 2005-05-10 Microscience, Ltd. Genes and proteins, and their use
EP2284182A1 (fr) 2000-10-27 2011-02-16 Novartis Vaccines and Diagnostics S.r.l. Acides nucléiques et protéines dérivés des groupes de streptocoques A et B
US7691571B2 (en) 2001-01-31 2010-04-06 Mayo Foundation For Medical Education And Research Detection of bordetella
WO2002066650A2 (fr) 2001-02-21 2002-08-29 Shire Biochem Inc. Polypeptides de streptococcus pyogenes et fragments d'adn correspondants
AU2002317107B2 (en) 2001-07-06 2008-06-12 Id Biomedical Corporation Group B streptococcus antigens and corresponding DNA fragments
GB0210128D0 (en) * 2002-05-02 2002-06-12 Chiron Spa Nucleic acids and proteins from streptococcus groups A & B
WO2004018683A1 (fr) * 2002-08-12 2004-03-04 Akzo Nobel N.V. Proteine streptococcus uberis, sequence d'acide nucleique codant pour cette proteine et utilisation de cette derniere dans un vaccin contre la mammite
US7074598B2 (en) 2002-09-25 2006-07-11 Mayo Foundation For Medical Education And Research Detection of vancomycin-resistant enterococcus spp.
US7365176B2 (en) 2002-09-26 2008-04-29 Mayo Foundation For Medical Education And Research Detection of Epstein-Barr virus
CN102174533A (zh) 2002-10-15 2011-09-07 英特塞尔股份公司 编码b族链球菌粘着因子的核酸、b族链球菌的粘着因子和它们的用途
EP2287315A1 (fr) 2003-03-04 2011-02-23 Intercell AG Antigènes pyogènes streptococcus
EP1615950A2 (fr) 2003-04-15 2006-01-18 Intercell AG Antigenes s-pneumoniae
CN101864431A (zh) 2003-05-07 2010-10-20 英特塞尔股份公司 无乳链球菌抗原ⅰ和ⅱ
US7709009B2 (en) 2003-07-31 2010-05-04 Novartis Vaccines And Diagnostics, Srl Immunogenic compositions for streptococcus pyogenes
WO2005028618A2 (fr) * 2003-09-15 2005-03-31 Chiron Corporation Compositions immunogenes pour streptococcus agalactiae
US8945589B2 (en) 2003-09-15 2015-02-03 Novartis Vaccines And Diagnostics, Srl Immunogenic compositions for Streptococcus agalactiae
US20070212311A1 (en) * 2003-10-07 2007-09-13 University Of Florida Research Foundation, Inc. Recombinant Alkalinizing Bacteria
US7427475B2 (en) 2003-11-18 2008-09-23 Mayo Foundation For Medical Education And Research Detection of group B streptococcus
EP2612679A1 (fr) * 2004-07-29 2013-07-10 Novartis Vaccines and Diagnostics, Inc. Compositions immunogènes pour une bactérie à gram positif telle que streptococcus agalactiae
JP2008525033A (ja) * 2004-12-22 2008-07-17 ノバルティス ヴァクシンズ アンド ダイアグノスティクス， インコーポレイテッド Ｂ群連鎖球菌
WO2006086438A2 (fr) * 2005-02-07 2006-08-17 Gen-Probe Incorporated Compositions et procedes pour detecter des streptocoques du groupe b
EP1919934A2 (fr) * 2005-05-13 2008-05-14 Novartis Vaccines and Diagnostics, Inc. Facteurs de resistance au serum de bacteries a gram positif
JP2009540819A (ja) * 2006-06-19 2009-11-26 ミュタビリス エス アー Ｂ群レンサ球菌の病原性に関与する遺伝子の同定
CN101490083A (zh) * 2006-07-07 2009-07-22 英特塞尔股份公司 小化脓性链球菌抗原及其用途
US8287885B2 (en) 2007-09-12 2012-10-16 Novartis Ag GAS57 mutant antigens and GAS57 antibodies
CA2758687A1 (fr) 2008-11-14 2010-05-20 Gen-Probe Incorporated Compositions, kits et procedes pour la detection d'acide nucleique de campylobacter
WO2012138470A2 (fr) 2011-04-04 2012-10-11 Intelligent Medical Devices, Inc. Oligonucléotides optimisés et leurs procédés d'utilisation pour la détection, l'isolement, l'amplification, la quantification, la surveillance, le criblage et le séquençage de streptococcus de groupe b
EP2557424A1 (fr) * 2011-08-11 2013-02-13 InGen Biosciences Procédé pour le diagnostic d'infections par les genres Streptococcus, Enterococcus et Pepstostreptococcus
CA2865028A1 (fr) * 2012-02-24 2013-08-29 Novartis Ag Proteines de pilus et compositions
DK3411389T3 (da) 2016-02-04 2021-06-21 Genovis Ab Nye streptokokproteaser
PL239045B1 (pl) * 2018-01-09 2021-11-02 Inst Immunologii I Terapii Doswiadczalnej Polskiej Akademii Nauk Epitop specyficzny dla zakaźnych Streptococcus agalactiae oraz sposób wykrywania zakażenia pacjenta szczepem Streptococcus agalactiae

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001014421A1 (fr) * 1999-08-25 2001-03-01 Medimmune, Inc. Homologues d'une proteine pneumococcique et fragments pour vaccins

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ID27482A (id) * 1998-02-20 2001-04-12 Iaf Biochem Int Antigen streptococcus kelompok b

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001014421A1 (fr) * 1999-08-25 2001-03-01 Medimmune, Inc. Homologues d'une proteine pneumococcique et fragments pour vaccins

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 11 February 1999 (1999-02-11), SPELLERBERG B. ET AL.: "Streptococcus agalactiae Lmb (lmb) gene, complete cds; and unknown gene", XP002221154, Database accession no. AF062533 *
DATABASE SWALL [online] 1 March 2001 (2001-03-01), DE BOEVER, E.H. ET AL.: "TraG-related protein", XP002221155, Database accession no. Q9F1G0 *
DORAN, T. I. ET AL.: "Factors Influencing Release of Type III Antigens by Group B Streptococci", INFECT. IMMUN., vol. 31, no. 2, February 1981 (1981-02-01), pages 615 - 623, XP002191322 *
ERIKA H. DE BOEVER ET AL.: "Enterococcus faecalis conjugative plasmid pAM373: complete nucleotide sequence and genetic analysis of sex phromone response", MOLECULAR MICROBIOLOGY, vol. 37, no. 6, 2000, pages 1327 - 1341 *
SPELLERBERG B ET AL: "LMB, A PROTEIN WITH SIMILARITIES TO THE LRAI ADHESIN FAMILY, MEDIATES ATTACHMENT OF STREPTOCOCCUS AGALACTIAE TO HUMAN LAMININ", INFECTION AND IMMUNITY, AMERICAN SOCIETY FOR MICROBIOLOGY. WASHINGTON, US, vol. 67, no. 2, AF062533, February 1999 (1999-02-01), pages 871 - 878, XP000973065, ISSN: 0019-9567 *

Also Published As

Publication number Publication date
WO2002092818A8 (fr) 2004-03-04
WO2002092818A2 (fr) 2002-11-21
AU2002319867A1 (en) 2002-11-25
FR2824074A1 (fr) 2002-10-31

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