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WO2002086074A3 - Compositions for delivery of compounds to cells and methods of use - Google Patents

Compositions for delivery of compounds to cells and methods of use Download PDF

Info

Publication number
WO2002086074A3
WO2002086074A3 PCT/US2002/012607 US0212607W WO02086074A3 WO 2002086074 A3 WO2002086074 A3 WO 2002086074A3 US 0212607 W US0212607 W US 0212607W WO 02086074 A3 WO02086074 A3 WO 02086074A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
delivery
compositions
cells
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2002/012607
Other languages
French (fr)
Other versions
WO2002086074A2 (en
Inventor
Clifford J Steer
Betsy T Kren
Cheryle Linehan-Stieers
Scott R Mcivor
Perry B Hackett
Srilalitha Belur
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Minnesota Twin Cities
University of Minnesota System
Original Assignee
University of Minnesota Twin Cities
University of Minnesota System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/861,014 external-priority patent/US20020115216A1/en
Application filed by University of Minnesota Twin Cities, University of Minnesota System filed Critical University of Minnesota Twin Cities
Priority to AU2002256304A priority Critical patent/AU2002256304A1/en
Publication of WO2002086074A2 publication Critical patent/WO2002086074A2/en
Publication of WO2002086074A3 publication Critical patent/WO2002086074A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/645—Polycationic or polyanionic oligopeptides, polypeptides or polyamino acids, e.g. polylysine, polyarginine, polyglutamic acid or peptide TAT

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention provides molecular complexes that include a DNA condensing reagent and a biologically active compound. The invention further provides methods for delivering a biologically active compound to a vertebrate cell, and methods for expressing a coding sequence in a vertebrate cell.
PCT/US2002/012607 2001-04-20 2002-04-22 Compositions for delivery of compounds to cells and methods of use Ceased WO2002086074A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002256304A AU2002256304A1 (en) 2001-04-20 2002-04-22 Compositions for delivery of compounds to cells and methods of use

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US28516701P 2001-04-20 2001-04-20
US28512101P 2001-04-20 2001-04-20
US60/285,167 2001-04-20
US60/285,121 2001-04-20
US09/861,014 2001-05-19
US09/861,014 US20020115216A1 (en) 2000-05-19 2001-05-19 Composition for delivery of compounds to cells

Publications (2)

Publication Number Publication Date
WO2002086074A2 WO2002086074A2 (en) 2002-10-31
WO2002086074A3 true WO2002086074A3 (en) 2003-07-17

Family

ID=27403505

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/012607 Ceased WO2002086074A2 (en) 2001-04-20 2002-04-22 Compositions for delivery of compounds to cells and methods of use

Country Status (2)

Country Link
AU (1) AU2002256304A1 (en)
WO (1) WO2002086074A2 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102017210143A1 (en) 2017-06-16 2018-12-20 Henkel Ag & Co. Kgaa Viscoelastic, solid surfactant composition
DE102017210141A1 (en) 2017-06-16 2018-12-20 Henkel Ag & Co. Kgaa Portion to provide surfactant-containing fleets
DE102017223456A1 (en) 2017-12-20 2019-06-27 Henkel Ag & Co. Kgaa Viscoelastic, high solids surfactant composition
EP3638755A1 (en) 2017-06-16 2020-04-22 Henkel AG & Co. KGaA Viscoelastic solid surfactant composition having a high surfactant content
DE102017223460A1 (en) 2017-12-20 2019-06-27 Henkel Ag & Co. Kgaa Viscose-elastic, high-surfactant, solid surfactant composition
WO2018229036A1 (en) 2017-06-16 2018-12-20 Henkel Ag & Co. Kgaa Viscoelastic, solid-state surfactant composition having a high surfactant content
DE102018201830A1 (en) 2018-02-06 2019-08-08 Henkel Ag & Co. Kgaa Viscoelastic, solid surfactant composition
DE102018209002A1 (en) 2018-06-07 2019-12-12 Henkel Ag & Co. Kgaa Detergent composition with yield value
DE102018219415A1 (en) 2018-11-14 2020-05-14 Henkel Ag & Co. Kgaa Textile pretreatment composition containing a shaped body with a low molecular weight gel former
DE102018219413A1 (en) 2018-11-14 2020-05-14 Henkel Ag & Co. Kgaa Textile pretreatment composition containing a shaped body with a glucosamine derivative as a low-molecular gelling agent
DE102018221671A1 (en) 2018-12-13 2020-06-18 Henkel Ag & Co. Kgaa Device and method for producing a water-soluble casing and detergent or cleaning agent portions containing this water-soluble casing with viscoelastic, solid filler substance
DE102018221674A1 (en) 2018-12-13 2020-06-18 Henkel Ag & Co. Kgaa Device and method for producing a water-soluble casing and detergent or cleaning agent portions containing this water-soluble casing
CN110438162B (en) * 2019-08-22 2021-06-25 广州晶欣生物科技有限公司 Improved non-liposome transfection kit and application method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6225121B1 (en) * 1992-09-14 2001-05-01 Institute Of Molecular Biology And Biotechnology/Forth Eukaryotic transposable element
WO2001081565A2 (en) * 2000-04-27 2001-11-01 Max-Delbrück-Centrum für Molekulare Medizin Sleeping beauty, a transposon vector with a broad host range for the genetic transformation in vertebrates
US6489458B2 (en) * 1997-03-11 2002-12-03 Regents Of The University Of Minnesota DNA-based transposon system for the introduction of nucleic acid into DNA of a cell

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6225121B1 (en) * 1992-09-14 2001-05-01 Institute Of Molecular Biology And Biotechnology/Forth Eukaryotic transposable element
US6489458B2 (en) * 1997-03-11 2002-12-03 Regents Of The University Of Minnesota DNA-based transposon system for the introduction of nucleic acid into DNA of a cell
WO2001081565A2 (en) * 2000-04-27 2001-11-01 Max-Delbrück-Centrum für Molekulare Medizin Sleeping beauty, a transposon vector with a broad host range for the genetic transformation in vertebrates
DE10120829A1 (en) * 2000-04-27 2001-12-20 Max Delbrueck Centrum Gene transfer method, useful in therapy, diagnosis and preparing transgenic animals, uses both components of the Sleeping Beauty transfer system

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
IVICS ET AL: "Molecular reconstruction of sleeping beauty, a TC-1-like transposon from fish and its transposition in human cells", CELL, vol. 91, 14 November 1997 (1997-11-14), pages 501 - 510, XP002946963 *
LUO ET AL.: "Chromosomal transposition of a Tc1/mariner-like element in mouse embryonic stem cells", PROC. NATL. ACAD. SCI. USA, vol. 95, September 1998 (1998-09-01), pages 10769 - 10773, XP002946962 *

Also Published As

Publication number Publication date
AU2002256304A1 (en) 2002-11-05
WO2002086074A2 (en) 2002-10-31

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