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WO2002085943A3 - Nucleic acids of the human abcc12 gene, vectors containing such nucleic acids and uses thereof - Google Patents

Nucleic acids of the human abcc12 gene, vectors containing such nucleic acids and uses thereof Download PDF

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Publication number
WO2002085943A3
WO2002085943A3 PCT/EP2002/003320 EP0203320W WO02085943A3 WO 2002085943 A3 WO2002085943 A3 WO 2002085943A3 EP 0203320 W EP0203320 W EP 0203320W WO 02085943 A3 WO02085943 A3 WO 02085943A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acids
gene
vectors containing
abcc12
abcc12 gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2002/003320
Other languages
French (fr)
Other versions
WO2002085943A2 (en
Inventor
Marie-Francoise Rosier-Montus
Catherine Prades
Isabelle Arnould-Reguigne
Patrice Denefle
Michael Dean
Rando Allikmets
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
US Department of Health and Human Services
Government of the United States of America
Original Assignee
Aventis Pharma SA
US Department of Health and Human Services
Government of the United States of America
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma SA, US Department of Health and Human Services, Government of the United States of America filed Critical Aventis Pharma SA
Priority to JP2002583469A priority Critical patent/JP2004537983A/en
Priority to CA002439693A priority patent/CA2439693A1/en
Priority to EP02712956A priority patent/EP1370585A2/en
Publication of WO2002085943A2 publication Critical patent/WO2002085943A2/en
Publication of WO2002085943A3 publication Critical patent/WO2002085943A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Psychology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The present invention relates to a novel human ABCC12 gene as well as the cDNAs encoding the novel short and long of ABCC12 proteins isoforms. The invention also relates to vectors and recombinant host cells comprising such nucleic acids, nucleotide probes and primers, and means for the detection of polymorphisms and mutations in the ABCC12 gene or in the corresponding proteins isoforms produced by the allelic form of the ABCC12 gene.
PCT/EP2002/003320 2001-03-05 2002-03-05 Nucleic acids of the human abcc12 gene, vectors containing such nucleic acids and uses thereof Ceased WO2002085943A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2002583469A JP2004537983A (en) 2001-03-05 2002-03-05 Nucleic acids of the human ABCC12 gene, vectors containing such nucleic acids, and uses thereof
CA002439693A CA2439693A1 (en) 2001-03-05 2002-03-05 Nucleic acids of the human abcc12 gene, vectors containing such nucleic acids and uses thereof
EP02712956A EP1370585A2 (en) 2001-03-05 2002-03-05 Nucleic acids of the human abcc12 gene, vectors containing such nucleic acids and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27275901P 2001-03-05 2001-03-05
US60/272,759 2001-03-05

Publications (2)

Publication Number Publication Date
WO2002085943A2 WO2002085943A2 (en) 2002-10-31
WO2002085943A3 true WO2002085943A3 (en) 2003-04-17

Family

ID=23041149

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/003320 Ceased WO2002085943A2 (en) 2001-03-05 2002-03-05 Nucleic acids of the human abcc12 gene, vectors containing such nucleic acids and uses thereof

Country Status (4)

Country Link
EP (1) EP1370585A2 (en)
JP (1) JP2004537983A (en)
CA (1) CA2439693A1 (en)
WO (1) WO2002085943A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002072632A2 (en) * 2001-03-05 2002-09-19 Aventis Pharma S.A. Nucleic acids of the human abcc11 gene, vectors containing such nucleic acids and uses thereof.

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001057214A2 (en) * 2000-02-03 2001-08-09 Lexicon Genetics Incorporated Human transporter proteins and polynucleotides encoding the same
WO2001075067A2 (en) * 2000-03-31 2001-10-11 Hyseq, Inc. Novel nucleic acids and polypeptides
WO2002072632A2 (en) * 2001-03-05 2002-09-19 Aventis Pharma S.A. Nucleic acids of the human abcc11 gene, vectors containing such nucleic acids and uses thereof.

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001057214A2 (en) * 2000-02-03 2001-08-09 Lexicon Genetics Incorporated Human transporter proteins and polynucleotides encoding the same
WO2001075067A2 (en) * 2000-03-31 2001-10-11 Hyseq, Inc. Novel nucleic acids and polypeptides
WO2002072632A2 (en) * 2001-03-05 2002-09-19 Aventis Pharma S.A. Nucleic acids of the human abcc11 gene, vectors containing such nucleic acids and uses thereof.

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
ALLIKMETS R ET AL: "Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the Expressed Sequence Tags Database", HUMAN MOLECULAR GENETICS, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 5, no. 10, 1996, pages 1649 - 1655, XP002120400, ISSN: 0964-6906 *
BENNETT LYNDA B ET AL: "A locus for paroxysmal kinesigenic dyskinesia maps to human chromosome 16.", NEUROLOGY, vol. 54, no. 1, 11 January 2000 (2000-01-11), pages 125 - 130, XP009004537, ISSN: 0028-3878 *
DATABASE EMBL [online] 1 February 2000 (2000-02-01), STRAUSBERG R: "hd13d01.x1 Soares_NFL_T_GBC_S1 Homo sapiens cDNA clone IMAGE:2909377 3' similar to TR:O14517 O14517 SMRP. ;, mRNA sequence.", XP002228124, Database accession no. AW341683 *
DATABASE EMBL [online] 21 May 1999 (1999-05-21), BRUCE D ET AL.,: "Homo sapiens chromosome 16 clone RP11-264A16, complete sequence.", XP002228126, Database accession no. AC007600 *
DATABASE GENESEQ [online] 13 February 2002 (2002-02-13), DRMANAC RT. ET AL.: "DNA encoding novel human diagnostic protein #25888.", XP002228127, Database accession no. AAS90084 *
DATABASE GENESEQ [online] 18 February 2002 (2002-02-18), DRMANAC RT ET AL.,: "Novel human diagnostic protein #25888.", XP002228128, Database accession no. ABG25897 *
DATABASE SWISS-PROT [online] 15 July 1998 (1998-07-15), BELINSKY MG, ET AL.,: "Multidrug resistance-associated protein 5 (Multi-specific organic anion tranporter-C) (MOAT-C) (pABC11) (SMRP).", XP002228125, Database accession no. O14517 *
TAMMUR J ET AL: "Two new genes from the human ATP-binding cassette transporter superfamily, ABCC11 and ABCC12, tandemly duplicated on chromosome 16q12", GENE: AN INTERNATIONAL JOURNAL ON GENES AND GENOMES, ELSEVIER SCIENCE PUBLISHERS, BARKING, GB, vol. 273, no. 1, 25 July 2001 (2001-07-25), pages 89 - 96, XP004296790, ISSN: 0378-1119 *
TOMITA HIRO-AKI ET AL: "Paroxysmal kinesigenic choreoathetosis locus maps to chromosome 16p11.2-q12.1.", AMERICAN JOURNAL OF HUMAN GENETICS, vol. 65, no. 6, December 1999 (1999-12-01), pages 1688 - 1697, XP002228122, ISSN: 0002-9297 *
YABUUCHI HIKARU ET AL: "Multiple splicing variants of two new human ATP-binding cassette transporters, ABCC11 and ABCC12.", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 288, no. 4, 9 November 2001 (2001-11-09), pages 933 - 939, XP002228123, ISSN: 0006-291X *

Also Published As

Publication number Publication date
JP2004537983A (en) 2004-12-24
EP1370585A2 (en) 2003-12-17
CA2439693A1 (en) 2002-10-31
WO2002085943A2 (en) 2002-10-31

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