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WO2002077237A3 - Transporters and ion channels - Google Patents

Transporters and ion channels Download PDF

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Publication number
WO2002077237A3
WO2002077237A3 PCT/US2002/003657 US0203657W WO02077237A3 WO 2002077237 A3 WO2002077237 A3 WO 2002077237A3 US 0203657 W US0203657 W US 0203657W WO 02077237 A3 WO02077237 A3 WO 02077237A3
Authority
WO
WIPO (PCT)
Prior art keywords
ion channels
trich
transporters
provides
polynucleotides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2002/003657
Other languages
French (fr)
Other versions
WO2002077237A2 (en
Inventor
Ernestine A Lee
Li Ding
Mariah R Baughn
Catherine M Tribouley
Christopher M Bruns
Vicki S Elliott
Narinder K Chawla
Ian J Forsythe
Brigitte E Raumann
Neil Burford
Preeti G Lal
Michael Thornton
Ameena R Gandhi
Chandra Arvizu
Monique G Yao
Henry Yue
Yuming Xu
April J A Hafalia
Craig H Ison
Huei-Mei Chen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Incyte Corp
Original Assignee
Incyte Genomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc filed Critical Incyte Genomics Inc
Priority to CA002438206A priority Critical patent/CA2438206A1/en
Priority to JP2002576679A priority patent/JP2004537283A/en
Priority to EP02753752A priority patent/EP1358330A2/en
Priority to US10/467,685 priority patent/US20040116666A1/en
Publication of WO2002077237A2 publication Critical patent/WO2002077237A2/en
Publication of WO2002077237A3 publication Critical patent/WO2002077237A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The invention provides human transporters and ion channels (TRICH) and polynucleotides which identify and encode TRICH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of TRICH.
PCT/US2002/003657 2001-02-09 2002-02-08 Transporters and ion channels Ceased WO2002077237A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002438206A CA2438206A1 (en) 2001-02-09 2002-02-08 Transporters and ion channels
JP2002576679A JP2004537283A (en) 2001-02-09 2002-02-08 Transporters and ion channels
EP02753752A EP1358330A2 (en) 2001-02-09 2002-02-08 Transporters and ion channels
US10/467,685 US20040116666A1 (en) 2002-02-08 2002-02-08 Transporters and ion channels

Applications Claiming Priority (14)

Application Number Priority Date Filing Date Title
US26789201P 2001-02-09 2001-02-09
US60/267,892 2001-02-09
US27116801P 2001-02-23 2001-02-23
US60/271,168 2001-02-23
US27289001P 2001-03-02 2001-03-02
US60/272,890 2001-03-02
US27686001P 2001-03-16 2001-03-16
US60/276,860 2001-03-16
US27825501P 2001-03-23 2001-03-23
US60/278,255 2001-03-23
US28053801P 2001-03-30 2001-03-30
US60/280,538 2001-03-30
US35135902P 2002-01-25 2002-01-25
US60/351,359 2002-01-25

Publications (2)

Publication Number Publication Date
WO2002077237A2 WO2002077237A2 (en) 2002-10-03
WO2002077237A3 true WO2002077237A3 (en) 2003-06-19

Family

ID=27569527

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/003657 Ceased WO2002077237A2 (en) 2001-02-09 2002-02-08 Transporters and ion channels

Country Status (4)

Country Link
EP (1) EP1358330A2 (en)
JP (1) JP2004537283A (en)
CA (1) CA2438206A1 (en)
WO (1) WO2002077237A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002061084A2 (en) * 2000-11-14 2002-08-08 Millennium Pharmaceuticals, Inc. Nt69, a nucleoside transporter family member and uses therefor
WO2002079472A2 (en) * 2000-12-19 2002-10-10 Pe Corporation (Ny) Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
US20040118060A1 (en) * 2001-04-20 2004-06-24 Jensen Bo Skaaning Ion channel arrays
US7504481B2 (en) 2001-08-02 2009-03-17 Bristol-Meyers Squibb Company TRP channel family member, LTRPC3 polypeptides
EP1473303B1 (en) 2002-01-18 2010-02-24 Takeda Pharmaceutical Company Limited Sodium dependent bile acid transporter and use thereof
WO2003095644A1 (en) * 2002-05-14 2003-11-20 Takeda Pharmaceutical Company Limited Novel proteins and dnas thereof
EP1589103A4 (en) 2003-01-17 2006-07-19 Astellas Pharma Inc Method of screening agent for improving memory and learning ability
US7344882B2 (en) 2003-05-12 2008-03-18 Bristol-Myers Squibb Company Polynucleotides encoding variants of the TRP channel family member, LTRPC3

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999018125A1 (en) * 1997-10-01 1999-04-15 St. Vincent's Institute Of Medical Research Human facilitative glucose transport protein glut8
WO2001092304A2 (en) * 2000-05-26 2001-12-06 Incyte Genomics, Inc. Transporters and ion channels
WO2002008261A2 (en) * 2000-07-26 2002-01-31 Stanford University Bstp-trans protein and related reagents and methods of use thereof
WO2002055701A2 (en) * 2000-12-15 2002-07-18 Millennium Pharm Inc Human sugar transporter proteins, potassium channel proteins, phospholipid transporter proteins and methods of use thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999018125A1 (en) * 1997-10-01 1999-04-15 St. Vincent's Institute Of Medical Research Human facilitative glucose transport protein glut8
WO2001092304A2 (en) * 2000-05-26 2001-12-06 Incyte Genomics, Inc. Transporters and ion channels
WO2002008261A2 (en) * 2000-07-26 2002-01-31 Stanford University Bstp-trans protein and related reagents and methods of use thereof
WO2002055701A2 (en) * 2000-12-15 2002-07-18 Millennium Pharm Inc Human sugar transporter proteins, potassium channel proteins, phospholipid transporter proteins and methods of use thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL_EST [online] 29 May 1995 (1995-05-29), HILLIER L ET AL: "Homa sapiens cDNA clone similar to xylose-proton symport", XP002222914, Database accession no. R59842 *
DATABASE EPOP [online] 16 August 2002 (2002-08-16), CURTIS RA: "Human sugar transproter proteins, potassium channel proteins, phospholipid transporter proteins and methos of use thereof", XP002222913, Database accession no. AX481744 *

Also Published As

Publication number Publication date
JP2004537283A (en) 2004-12-16
CA2438206A1 (en) 2002-10-03
EP1358330A2 (en) 2003-11-05
WO2002077237A2 (en) 2002-10-03

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