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WO2002066504A3 - Obtention d'un plus grand nombre d'interactions proteine-proteine dans la saccharomyces cerevisiae - Google Patents

Obtention d'un plus grand nombre d'interactions proteine-proteine dans la saccharomyces cerevisiae Download PDF

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Publication number
WO2002066504A3
WO2002066504A3 PCT/EP2002/002299 EP0202299W WO02066504A3 WO 2002066504 A3 WO2002066504 A3 WO 2002066504A3 EP 0202299 W EP0202299 W EP 0202299W WO 02066504 A3 WO02066504 A3 WO 02066504A3
Authority
WO
WIPO (PCT)
Prior art keywords
protein
saccharomyces cerevisiae
polypeptides
proteins
interactions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2002/002299
Other languages
English (en)
Other versions
WO2002066504A2 (fr
Inventor
Pierre Legrain
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aton SA
Original Assignee
Hybrigenics SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hybrigenics SA filed Critical Hybrigenics SA
Priority to AU2002251058A priority Critical patent/AU2002251058A1/en
Publication of WO2002066504A2 publication Critical patent/WO2002066504A2/fr
Anticipated expiration legal-status Critical
Publication of WO2002066504A3 publication Critical patent/WO2002066504A3/fr
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1055—Protein x Protein interaction, e.g. two hybrid selection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C07K14/395—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts from Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Plant Pathology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Immunology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Cette invention se rapporte à des protéines qui interagissent avec d'autres protéines de Saccharomyces cerevisiae. De manière plus spécifique, cette invention se rapporte : à des complexes de polypeptides ou de polynucléotides codant les polypeptides et des fragments de ces polypeptides ; à des anticorps dirigés contre ces complexes ; à des domaines d'interaction sélectionnés (SID®), qui sont identifiés grâce aux interactions protéine-protéine ; à des procédés de criblage d'agents qui modulent l'interaction des protéines ainsi qu'à des compositions pouvant moduler les interactions protéine-protéine, telles que des médicaments dans des compositions pharmaceutiques.
PCT/EP2002/002299 2001-02-16 2002-02-14 Obtention d'un plus grand nombre d'interactions proteine-proteine dans la saccharomyces cerevisiae Ceased WO2002066504A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002251058A AU2002251058A1 (en) 2001-02-16 2002-02-14 Protein-protein interactions in saccharomyces cerevisiae

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26926601P 2001-02-16 2001-02-16
US60/269,266 2001-02-16

Publications (2)

Publication Number Publication Date
WO2002066504A2 WO2002066504A2 (fr) 2002-08-29
WO2002066504A3 true WO2002066504A3 (fr) 2003-12-18

Family

ID=23026527

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/002299 Ceased WO2002066504A2 (fr) 2001-02-16 2002-02-14 Obtention d'un plus grand nombre d'interactions proteine-proteine dans la saccharomyces cerevisiae

Country Status (2)

Country Link
AU (1) AU2002251058A1 (fr)
WO (1) WO2002066504A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2511295A1 (fr) * 2011-04-15 2012-10-17 Institut National De La Sante Et De La Recherche Medicale Compositions pour la prévention et/ou le traitement d'une infection par un virus VIH-1

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6083693A (en) * 1996-06-14 2000-07-04 Curagen Corporation Identification and comparison of protein-protein interactions that occur in populations
WO2000066722A1 (fr) * 1999-04-30 2000-11-09 Hybrigenics S.A. Collection d'adn procaryote d'helicobacter pylori permettant l'identification des interactions proteine-proteine utilisable pour deux systemes hybrides et applications
WO2002050259A2 (fr) * 2000-12-18 2002-06-27 National Research Council Of Canada Compositions, methods and kits for identifying protein-protein interaction disrupting agents

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6083693A (en) * 1996-06-14 2000-07-04 Curagen Corporation Identification and comparison of protein-protein interactions that occur in populations
WO2000066722A1 (fr) * 1999-04-30 2000-11-09 Hybrigenics S.A. Collection d'adn procaryote d'helicobacter pylori permettant l'identification des interactions proteine-proteine utilisable pour deux systemes hybrides et applications
WO2002050259A2 (fr) * 2000-12-18 2002-06-27 National Research Council Of Canada Compositions, methods and kits for identifying protein-protein interaction disrupting agents

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
FINLEY R L ET AL: "TWO-HYBRID ANALYSIS OF GENETIC REGULATORY NETWORKS. THE YEAST TWO-HYBRID SYSTEM", YEAST TWO-HYBRID SYSTEM ( ADVANCES IN MOLECULAR BIOLOGY ), XX, XX, PAGE(S) 197-214, XP002922642 *
VIDAL M ET AL: "REVERSE TWO-HYBRID AND ONE-HYBRID SYSTEMS TO DETECT DISSOCIATION OF PROTEIN-PROTEIN AND DNA-PROTEIN INTERACTIONS", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 93, 1 September 1996 (1996-09-01), pages 10315 - 10320, XP000749719, ISSN: 0027-8424 *

Also Published As

Publication number Publication date
AU2002251058A1 (en) 2002-09-04
WO2002066504A2 (fr) 2002-08-29

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