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WO2002061405A3 - Method and hand-held device for fluorescence detection - Google Patents

Method and hand-held device for fluorescence detection Download PDF

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Publication number
WO2002061405A3
WO2002061405A3 PCT/CA2002/000129 CA0200129W WO02061405A3 WO 2002061405 A3 WO2002061405 A3 WO 2002061405A3 CA 0200129 W CA0200129 W CA 0200129W WO 02061405 A3 WO02061405 A3 WO 02061405A3
Authority
WO
WIPO (PCT)
Prior art keywords
sample
fluorescence
held device
hand
fluorescence detection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CA2002/000129
Other languages
French (fr)
Other versions
WO2002061405A2 (en
Inventor
Roy H Pottier
Eva F Dickson
Frank Fischer
James C Kennedy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to AU2002227838A priority Critical patent/AU2002227838A1/en
Publication of WO2002061405A2 publication Critical patent/WO2002061405A2/en
Publication of WO2002061405A3 publication Critical patent/WO2002061405A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0601—Apparatus for use inside the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/062—Photodynamic therapy, i.e. excitation of an agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G01N2021/6419—Excitation at two or more wavelengths
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G01N2021/6421—Measuring at two or more wavelengths
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/02—Mechanical
    • G01N2201/022—Casings
    • G01N2201/0221—Portable; cableless; compact; hand-held

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

The present invention provides a portable hand held device (10) for exciting and detecting fluorescence in a biological sample (16) for discriminating between normal and diseased tissue. The device includes a light source (12) to irradiate the sample with excitation light, a detector (18) to detect fluorescence emitted by the sample, the fluorescence resulting from irradiation of the sample with excitation light, and an indicator (26) coupled to the detector to output an indication of the fluorescence. This portable device can be used in a clinic or doctor's office for photodiagnosis (PD) or management of photodynamic therapy (PDT).
PCT/CA2002/000129 2001-01-31 2002-01-31 Method and hand-held device for fluorescence detection Ceased WO2002061405A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002227838A AU2002227838A1 (en) 2001-01-31 2002-01-31 Method and hand-held device for fluorescence detection

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26516401P 2001-01-31 2001-01-31
US60/265,164 2001-01-31

Publications (2)

Publication Number Publication Date
WO2002061405A2 WO2002061405A2 (en) 2002-08-08
WO2002061405A3 true WO2002061405A3 (en) 2002-11-14

Family

ID=23009289

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA2002/000129 Ceased WO2002061405A2 (en) 2001-01-31 2002-01-31 Method and hand-held device for fluorescence detection

Country Status (2)

Country Link
AU (1) AU2002227838A1 (en)
WO (1) WO2002061405A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9955873B2 (en) 2013-12-16 2018-05-01 Samsung Medison Co., Ltd. Photoacoustic probe and photoacoustic diagnostic apparatus

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7738032B2 (en) 2001-11-08 2010-06-15 Johnson & Johnson Consumer Companies, Inc. Apparatus for and method of taking and viewing images of the skin
FR2881225B1 (en) * 2005-01-21 2007-10-26 Cypher Science Sarl PORTABLE DETECTION APPARATUS FOR FIELD DETECTION OF FLUORESCENT-MARKING ELEMENTS
US20060244961A1 (en) * 2005-04-29 2006-11-02 Cole Curtis A Topical composition detection
US20060246020A1 (en) * 2005-04-29 2006-11-02 Cole Curtis A Topical composition detection
US20070004972A1 (en) * 2005-06-29 2007-01-04 Johnson & Johnson Consumer Companies, Inc. Handheld device for determining skin age, proliferation status and photodamage level
HRP20060149B1 (en) * 2006-04-19 2008-11-30 Institut "Ruđer Bošković" Intelligent sequential illuminator photodynamic therapy
US7558416B2 (en) 2006-10-02 2009-07-07 Johnson & Johnson Consumer Companies, Inc. Apparatus and method for measuring photodamage to skin
EP1912059A1 (en) * 2006-10-11 2008-04-16 Basf Se Mobile device for fluorescence detection and its use
WO2008106965A1 (en) * 2007-03-06 2008-09-12 Dia Medico Aps Method and apparatus for in vivo determination of skin fluorescence
FR2916850B1 (en) * 2007-06-01 2013-02-01 Force A PLANT VEGETABLE ANALYSIS APPARATUS, METHOD FOR MONITORING OR CARTOGRAPHY OF CONDITION OR EVOLUTION OF CULTURE, AND METHOD FOR MANAGING PLANT TREATMENT
EP3501384B1 (en) 2008-05-20 2024-07-17 University Health Network Method for fluorescence-based imaging and monitoring
FR2936252B1 (en) * 2008-09-23 2010-11-05 Millipore Corp DEVICE FOR MICROBIOLOGICAL ANALYSIS.
FR2936251B1 (en) * 2008-09-23 2010-11-05 Millipore Corp DEVICE FOR MICROBIOLOGICAL ANALYSIS.
LU91641B1 (en) * 2010-01-21 2011-07-22 Ct De Rech Public Gabriel Lippmann Cancerous or pre-cancerous tissue visualization method and device
FR2955763B1 (en) 2010-02-02 2012-03-09 Commissariat Energie Atomique BI-SPECTRAL PEROPERATIVE OPTIC PROBE
US20150011897A1 (en) * 2012-01-30 2015-01-08 Ccs Inc. Illumination device for tumor detection and illumination device for examinations
WO2014201009A2 (en) * 2013-06-10 2014-12-18 Relevant Play, Llc Systems and methods for infrared detection
CA2955976A1 (en) 2014-07-24 2016-01-28 University Health Network Collection and analysis of data for diagnostic purposes
ES2604304B1 (en) * 2015-09-03 2018-02-22 Universidad De Málaga LED-based lighting device with automated dose control for photodiagnosis of skin diseases related to light exposure, related applications and methods
EP3475873A4 (en) 2016-06-24 2020-02-19 Relevant Play, LLC. Authenticable digital code and associated systems and methods
US10132752B2 (en) 2017-01-27 2018-11-20 The United States Of America, As Represented By The Secretary Of The Navy Hand-held laser biosensor
WO2020014786A1 (en) * 2018-07-17 2020-01-23 Kerber Thomas Bernard Fluoresence imaging apparatus and method

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4608990A (en) * 1983-09-12 1986-09-02 Elings Virgil B Measuring skin perfusion
US5723338A (en) * 1994-11-04 1998-03-03 Amoco Corporation Tagging hydrocarbons for subsequent identification
WO1999066831A2 (en) * 1998-06-19 1999-12-29 Karl Storz Gmbh & Co. Kg. Utilization of 5-aminolevulinic acid or a derivative thereof for photodynamic diagnosis or photodynamic therapy of diseases of the parodontium and teeth
US6069689A (en) * 1997-04-16 2000-05-30 Derma Technologies, Inc. Apparatus and methods relating to optical systems for diagnosis of skin diseases
WO2000075642A1 (en) * 1999-06-06 2000-12-14 Planto Gmbh Device for measuring laser-induced fluorescence of pigments and/or environmental pollutants

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4608990A (en) * 1983-09-12 1986-09-02 Elings Virgil B Measuring skin perfusion
US5723338A (en) * 1994-11-04 1998-03-03 Amoco Corporation Tagging hydrocarbons for subsequent identification
US6069689A (en) * 1997-04-16 2000-05-30 Derma Technologies, Inc. Apparatus and methods relating to optical systems for diagnosis of skin diseases
WO1999066831A2 (en) * 1998-06-19 1999-12-29 Karl Storz Gmbh & Co. Kg. Utilization of 5-aminolevulinic acid or a derivative thereof for photodynamic diagnosis or photodynamic therapy of diseases of the parodontium and teeth
WO2000075642A1 (en) * 1999-06-06 2000-12-14 Planto Gmbh Device for measuring laser-induced fluorescence of pigments and/or environmental pollutants

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9955873B2 (en) 2013-12-16 2018-05-01 Samsung Medison Co., Ltd. Photoacoustic probe and photoacoustic diagnostic apparatus

Also Published As

Publication number Publication date
AU2002227838A1 (en) 2002-08-12
WO2002061405A2 (en) 2002-08-08

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