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WO2002059151A3 - Isolated human g-protein coupled receptors, nucleic acid molecules encoding human gpcr proteins, and uses thereof - Google Patents

Isolated human g-protein coupled receptors, nucleic acid molecules encoding human gpcr proteins, and uses thereof Download PDF

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Publication number
WO2002059151A3
WO2002059151A3 PCT/US2001/042978 US0142978W WO02059151A3 WO 2002059151 A3 WO2002059151 A3 WO 2002059151A3 US 0142978 W US0142978 W US 0142978W WO 02059151 A3 WO02059151 A3 WO 02059151A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
acid molecules
molecules encoding
protein coupled
coupled receptors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/042978
Other languages
French (fr)
Other versions
WO2002059151A2 (en
Inventor
Zhenya Li
Anibal Cravchik
Natalia Milshina
Ming-Hui Wei
Karen A Ketchum
Francesco Valentina Di
Ellen M Beasley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Biosystems Inc
Original Assignee
PE Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PE Corp filed Critical PE Corp
Publication of WO2002059151A2 publication Critical patent/WO2002059151A2/en
Publication of WO2002059151A3 publication Critical patent/WO2002059151A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the GPCR peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthlogs and paralogs of the GPCR peptides and methods of identifying modulators of the GPCR peptides.
PCT/US2001/042978 2001-01-26 2001-11-06 Isolated human g-protein coupled receptors, nucleic acid molecules encoding human gpcr proteins, and uses thereof Ceased WO2002059151A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76974101A 2001-01-26 2001-01-26
US09/769,741 2001-01-26

Publications (2)

Publication Number Publication Date
WO2002059151A2 WO2002059151A2 (en) 2002-08-01
WO2002059151A3 true WO2002059151A3 (en) 2003-04-17

Family

ID=25086376

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/042978 Ceased WO2002059151A2 (en) 2001-01-26 2001-11-06 Isolated human g-protein coupled receptors, nucleic acid molecules encoding human gpcr proteins, and uses thereof

Country Status (1)

Country Link
WO (1) WO2002059151A2 (en)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998020040A1 (en) * 1996-11-07 1998-05-14 Incyte Pharmaceuticals, Inc. Novel histamine h2 receptor
WO2001036471A2 (en) * 1999-11-17 2001-05-25 Arena Pharmaceuticals, Inc. Endogenous and non-endogenous versions of human g protein-coupled receptors
WO2001062797A2 (en) * 2000-02-23 2001-08-30 Pharmacia & Upjohn Company G protein-coupled receptors
WO2001081410A2 (en) * 2000-04-25 2001-11-01 Pharmacia & Upjohn Company G protein-coupled receptors
WO2001088126A2 (en) * 2000-05-15 2001-11-22 Bayer Aktiengesellschaft REGULATION OF HUMAN α1Α ADRENERGIC RECEPTOR-LIKE G PROTEIN-COUPLED RECEPTOR
EP1243648A1 (en) * 1999-12-28 2002-09-25 Mitsubishi Pharma Corporation Novel guanosine triphosphate-binding protein-coupled receptors, genes thereof and production and uses thereof

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998020040A1 (en) * 1996-11-07 1998-05-14 Incyte Pharmaceuticals, Inc. Novel histamine h2 receptor
WO2001036471A2 (en) * 1999-11-17 2001-05-25 Arena Pharmaceuticals, Inc. Endogenous and non-endogenous versions of human g protein-coupled receptors
EP1243648A1 (en) * 1999-12-28 2002-09-25 Mitsubishi Pharma Corporation Novel guanosine triphosphate-binding protein-coupled receptors, genes thereof and production and uses thereof
WO2001062797A2 (en) * 2000-02-23 2001-08-30 Pharmacia & Upjohn Company G protein-coupled receptors
WO2001081410A2 (en) * 2000-04-25 2001-11-01 Pharmacia & Upjohn Company G protein-coupled receptors
WO2001088126A2 (en) * 2000-05-15 2001-11-22 Bayer Aktiengesellschaft REGULATION OF HUMAN α1Α ADRENERGIC RECEPTOR-LIKE G PROTEIN-COUPLED RECEPTOR

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
HIRASAWA AKIRA ET AL: "Cloning, functional expression and tissue distribution of human alpha-1C-adrenoceptor splice variants.", FEBS LETTERS, vol. 363, no. 3, 1995, pages 256 - 260, XP002216676, ISSN: 0014-5793 *

Also Published As

Publication number Publication date
WO2002059151A2 (en) 2002-08-01

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