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WO2002043566A3 - Devices and methods for treating low blood sugar levels - Google Patents

Devices and methods for treating low blood sugar levels Download PDF

Info

Publication number
WO2002043566A3
WO2002043566A3 PCT/US2001/044552 US0144552W WO0243566A3 WO 2002043566 A3 WO2002043566 A3 WO 2002043566A3 US 0144552 W US0144552 W US 0144552W WO 0243566 A3 WO0243566 A3 WO 0243566A3
Authority
WO
WIPO (PCT)
Prior art keywords
subject
source
area
intact skin
devices
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/044552
Other languages
French (fr)
Other versions
WO2002043566A2 (en
Inventor
Martin G Baum
Roger T Putman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to AU2002230509A priority Critical patent/AU2002230509A1/en
Publication of WO2002043566A2 publication Critical patent/WO2002043566A2/en
Publication of WO2002043566A3 publication Critical patent/WO2002043566A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention relates to methods and devices employed to control the onset of blood sugar levels below a predetermined minimum level over an extended period of time. The invention includes methods and devices for producing a therapeutic effect in a subject including placing a source of glucose or glucagon in a transdermal patch in transmitting relationship to an area of intact skin; and administering glucose or glucagon to the subject from the source through the area of intact skin for an extended period of time at a therapeutically effective rate for a substantial portion of the extended period of time to prevent the onset of a low blood sugar level in the subject. The methods and devices may include administering glucose or glucagon to the subject from the source through the area of intact skin for at least 4 hours, or longer, perhaps 24 hours or more, and are particularly well suited for administering glucose or glucagon to the subject from the source through the area of intact skin between usual sleeping hours. Additional therapeutic substances may also be administered to the subject from the source through the area of intact skin, including one or more nutritional supplements such as vitamins A, C, or D.
PCT/US2001/044552 2000-11-28 2001-11-28 Devices and methods for treating low blood sugar levels Ceased WO2002043566A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002230509A AU2002230509A1 (en) 2000-11-28 2001-11-28 Devices and methods for treating low blood sugar levels

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72383700A 2000-11-28 2000-11-28
US09/723,837 2000-11-28

Publications (2)

Publication Number Publication Date
WO2002043566A2 WO2002043566A2 (en) 2002-06-06
WO2002043566A3 true WO2002043566A3 (en) 2002-09-26

Family

ID=24907892

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/044552 Ceased WO2002043566A2 (en) 2000-11-28 2001-11-28 Devices and methods for treating low blood sugar levels

Country Status (2)

Country Link
AU (1) AU2002230509A1 (en)
WO (1) WO2002043566A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7655618B2 (en) 2002-12-27 2010-02-02 Diobex, Inc. Compositions and methods for the prevention and control of insulin-induced hypoglycemia
WO2004060387A1 (en) 2002-12-27 2004-07-22 Diobex, Inc. Compositions and methods for the prevention and control of insulin-induced hypoglycemia
US7591801B2 (en) 2004-02-26 2009-09-22 Dexcom, Inc. Integrated delivery device for continuous glucose sensor
EP4098177A1 (en) 2007-10-09 2022-12-07 DexCom, Inc. Integrated insulin delivery system with continuous glucose sensor
AU2008316630A1 (en) 2007-10-25 2009-04-30 Dexcom, Inc. Systems and methods for processing sensor data

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5234906A (en) * 1991-01-10 1993-08-10 Amylin Pharmaceuticals, Inc. Hyperglycemic compositions
US5360614A (en) * 1993-04-26 1994-11-01 The Estee Corporation Method of controlling the release of carbohydrates by encapsulation and composition therefor
US5707641A (en) * 1994-10-13 1998-01-13 Pharmaderm Research & Development Ltd. Formulations comprising therapeutically-active proteins or polypeptides
US5766620A (en) * 1995-10-23 1998-06-16 Theratech, Inc. Buccal delivery of glucagon-like insulinotropic peptides

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5234906A (en) * 1991-01-10 1993-08-10 Amylin Pharmaceuticals, Inc. Hyperglycemic compositions
US5360614A (en) * 1993-04-26 1994-11-01 The Estee Corporation Method of controlling the release of carbohydrates by encapsulation and composition therefor
US5707641A (en) * 1994-10-13 1998-01-13 Pharmaderm Research & Development Ltd. Formulations comprising therapeutically-active proteins or polypeptides
US5766620A (en) * 1995-10-23 1998-06-16 Theratech, Inc. Buccal delivery of glucagon-like insulinotropic peptides

Also Published As

Publication number Publication date
WO2002043566A2 (en) 2002-06-06
AU2002230509A1 (en) 2002-06-11

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