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WO2001036869A1 - Dispositif d'apport de lumiere - Google Patents

Dispositif d'apport de lumiere Download PDF

Info

Publication number
WO2001036869A1
WO2001036869A1 PCT/GB2000/004373 GB0004373W WO0136869A1 WO 2001036869 A1 WO2001036869 A1 WO 2001036869A1 GB 0004373 W GB0004373 W GB 0004373W WO 0136869 A1 WO0136869 A1 WO 0136869A1
Authority
WO
WIPO (PCT)
Prior art keywords
outlet
light
inlet
source
cavity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB2000/004373
Other languages
English (en)
Inventor
Julian Douglas Fairman
Hugh Douglas Fairman
Stephen Edward Gore
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to AU14041/01A priority Critical patent/AU1404101A/en
Publication of WO2001036869A1 publication Critical patent/WO2001036869A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/0001—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings specially adapted for lighting devices or systems
    • G02B6/0005—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings specially adapted for lighting devices or systems the light guides being of the fibre type
    • G02B6/001—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings specially adapted for lighting devices or systems the light guides being of the fibre type the light being emitted along at least a portion of the lateral surface of the fibre
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/062—Photodynamic therapy, i.e. excitation of an agent

Definitions

  • This invention relates to a light delivery device and in particular, but not exclusively, to a device for delivering photo-therapeutic light or light for use in photo-dynamic therapy.
  • the drug is administered to the patient in a completely darkened environment and the surgeon then illuminates the area of the body, where it is required that the cells be killed i.e. at the site of the tumour.
  • the area of the body where it is required that the cells be killed i.e. at the site of the tumour.
  • US-A-5835648 and WO-A-90/00420 both describe light delivery devices involving cup-like bodies which can be engaged against the tissue surface in an attempt to define an area of illumination.
  • Each of them rely on the inside of the cup-like body being extremely reflective, with the result that the area of illumination is either confined within an area smaller than the outlet of the cup and/or the uniformity of the illumination is uncertain, because it in part depends on the reflectivity of the surface being illuminated.
  • neither configuration is particularly suitable for use in narrow tubes, such as an oesophagus .
  • the Applicant's objective is to remove or mitigate at least some of these disadvantages with various embodiments of the invention.
  • the invention consists in a light delivery device comprising a body defining a cavity having an inlet for receiving light from a source and an outlet opposite the inlet for irradiating an area of a surface facing the outlet whilst the body shields surrounding parts of the surface characterised in that the surface of the cavity extending between the inlet and the outlet is anti-or non- reflective.
  • the body may be hollow and in the shape of a pyramid, a frusto-pyramid, a cone or a frusto-cone. Additionally or alternatively the upper part of the body may be narrower than the lower part and the inlet may be at or adjacent the top of the body and the outlet at or adjacent the bottom.
  • the location of the source and the dimensions of the body may be such that the light will illuminate at least the whole of the outlet. In this case any light which falls directly on the anti-reflective surface is effectively lost and so the illumination which occurs through the outlet will be constant and capable of calibration. Further this "whole outlet” approach enables the surgeon to know precisely what part of the surface of the patients tissue has been illuminated.
  • the device may further include a shutter for closing or partially closing the outlet.
  • the body may be at least generally cylindrical and the outlet may be in the form of a slot .
  • This arrangement is particularly suitable where tumours or the like occur in thin tubes such as the oesophagus .
  • the extent of illumination can again be well defined.
  • the dimensions of the slot can be readily adjusted or the slot can be closed off completely until such time as illumination is required.
  • a particulary convenient embodiment of the shutter in that case is in the form of a sleeve surrounding the body and having a further slot or aperture formed therein so that the dimensions of the outlet slot can be adjusted by the degree of overlap between the slots.
  • the sleeve may have one or more slots, to provide effectively calibrated outlets .
  • the light source could be located at the inlet directly, but more conveniently it will be remote and connected to the light source by a fibre optic or other light wave guide.
  • the device may include the light source.
  • the device may further include a handle attached to the body and an interconnection may be provided whereby the relative positions of the handle and body are adjustable.
  • the handle may act as a guide for a fibre optic .
  • the body may conveniently be formed of surgical steel or other appropriate material and the cavity may be coated, by an anti-reflective surface or the material itself may be rendered anti-reflective.
  • the outer surface of the device may also be anti-reflective.
  • Figure 1 is a schematic part-sectional view of a light delivery device applied to tissue;
  • Figure 2 is an enlargement of the indicated area in
  • Figure 3 is a perspective view of a practical embodiment of the invention.
  • Figure 4 is an exploded view of the device of Figure 3;
  • Figures 5a and 5b are perspective views of an alternative device with a shutter in a respective position
  • Figures 6a - c are sectional views of the embodiment of Figure 5 with the shutter in different positions;
  • Figure 7 is an enlarged cross-sectional view of the operative end of the embodiment of Figure 5.
  • Figure 8 shows the device of Figure 5 in use in situ.
  • a light delivery system generally indicated at 10, comprises a frusto-cone 11 which defines a cavity 12 having an anti-reflective coating 13.
  • An optical head 14 can be mounted at the upper or inlet end 15 of the body 11.
  • the optical head is in turn connected to a light source, such as a laser, 16 by a fibre optic 17.
  • the cone 11 defines an outlet 16 for light emanating from the head 14.
  • the geometry of the device is selected so that the cone of light 19 which is emitted from the head 14 illuminates an area, which coincides with the cross-sectional area of the outlet 18.
  • the device will work with its full efficacy. If some of the light strikes the coating 13, then it will simply be absorbed and the illumination through the outlet 18 will be constant. Thus when the body 11 is pressed against the surface
  • Figure 2 shows the body 11 lightly engaged against the surface 20, but in practice it will be pressed sufficiently hard against the surface 20 to remove the effect of any irregularities. This also has the advantage that it marks the skin around the area which has been treated.
  • Figures 3 and 4 show how the device 10 can conveniently include a handle 23, which can both act as a guide for the fibre optic and a means of manipulation for the surgeon.
  • a pivot ratchet mechanism is provided at 24 to allow the relative orientations of the body 11 and the handle 23 to be altered as required for the particular procedure .
  • the method of using the device 10 has already been outlined above.
  • the device 10 of Figures 1 - 4 is not particularly suitable for the treatment of tumours and the like in relatively narrow passageways such as the oesophagus .
  • An alternative device 10a is therefore illustrated in Figures 5 and 6.
  • a body 11a is generally cylindrical and continuous with the handle 23a, up which the fibre optic 17a can be fed.
  • the body defines a generally cylindrical cavity 12a, which again has an anti-reflective surface 13a.
  • the cavity 12a has a slot-like opening 25 to one side.
  • a sleeve 26 surrounds the body 11 and is rotatably mounted thereon by means of a circular crimped indentation 27 which runs in a co-operating annular groove 28 in the body. Conveniently the sleeve 26 is tensioned in this position by a spring 29, so that there is sufficient friction to maintain the sleeve 26 in any position in which it is placed.
  • the sleeve has slots 30 and 31 which can be respectively aligned with the outlet 25 so as to define a particular illumination.
  • FIG. 8 shows the device 10a in use in a bodily tube 32, such as an oesophagus, treating an area 33. Whilst this arrangement does not provide quite such good shielding of the surrounding area, the relatively small dimensions of the tube, in which the device is being used, means that the shielding is probably adequate.

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

L'invention concerne un système d'apport de lumière, indiqué en général par le numéro (10), lequel système comprend un corps tronconique (11) définissant une cavité (12) pourvue d'une revêtement antireflet (13). Une tête optique (14), qui peut être montée au niveau de l'extrémité (15) supérieure ou d'entrée du corps (11), est reliée à une source de lumière, notamment un laser (16), par l'intermédiaire d'une fibre optique (17). Le cône (11) définit un orifice de sortie (16) pour la lumière émanant de ladite tête (14).
PCT/GB2000/004373 1999-11-19 2000-11-17 Dispositif d'apport de lumiere Ceased WO2001036869A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU14041/01A AU1404101A (en) 1999-11-19 2000-11-17 Light delivery device

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9927305.4 1999-11-19
GBGB9927305.4A GB9927305D0 (en) 1999-11-19 1999-11-19 Light delivery device

Publications (1)

Publication Number Publication Date
WO2001036869A1 true WO2001036869A1 (fr) 2001-05-25

Family

ID=10864757

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2000/004373 Ceased WO2001036869A1 (fr) 1999-11-19 2000-11-17 Dispositif d'apport de lumiere

Country Status (3)

Country Link
AU (1) AU1404101A (fr)
GB (1) GB9927305D0 (fr)
WO (1) WO2001036869A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010100540A1 (fr) * 2009-03-02 2010-09-10 Michal Fraier Appareil portable comportant des unités d'extension déformables pour application d'un rayonnement sur la peau

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990000420A1 (fr) * 1988-07-13 1990-01-25 Adrian Charles Rowland Systeme d'amenee de lumiere
US5835648A (en) * 1996-03-07 1998-11-10 Miravant Systems, Inc. Surface illuminator for photodynamic therapy

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990000420A1 (fr) * 1988-07-13 1990-01-25 Adrian Charles Rowland Systeme d'amenee de lumiere
US5835648A (en) * 1996-03-07 1998-11-10 Miravant Systems, Inc. Surface illuminator for photodynamic therapy

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010100540A1 (fr) * 2009-03-02 2010-09-10 Michal Fraier Appareil portable comportant des unités d'extension déformables pour application d'un rayonnement sur la peau

Also Published As

Publication number Publication date
GB9927305D0 (en) 2000-01-12
AU1404101A (en) 2001-05-30

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