[go: up one dir, main page]

WO2001031579A3 - Procedes et dispositifs permettant d'identifier des motifs dans des systemes biologiques et procedes d'utilisation correspondants - Google Patents

Procedes et dispositifs permettant d'identifier des motifs dans des systemes biologiques et procedes d'utilisation correspondants Download PDF

Info

Publication number
WO2001031579A3
WO2001031579A3 PCT/US2000/029712 US0029712W WO0131579A3 WO 2001031579 A3 WO2001031579 A3 WO 2001031579A3 US 0029712 W US0029712 W US 0029712W WO 0131579 A3 WO0131579 A3 WO 0131579A3
Authority
WO
WIPO (PCT)
Prior art keywords
patterns
methods
devices
biological
identifying
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2000/029712
Other languages
English (en)
Other versions
WO2001031579A2 (fr
Inventor
Stephen D Barnhill
Isabelle Guyon
Jason Weston
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BARNHILL TECHNOLOGIES LLC
Original Assignee
BARNHILL TECHNOLOGIES LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/568,301 external-priority patent/US6427141B1/en
Priority claimed from US09/578,011 external-priority patent/US6658395B1/en
Priority claimed from US09/633,850 external-priority patent/US6789069B1/en
Application filed by BARNHILL TECHNOLOGIES LLC filed Critical BARNHILL TECHNOLOGIES LLC
Priority to AU13505/01A priority Critical patent/AU1350501A/en
Publication of WO2001031579A2 publication Critical patent/WO2001031579A2/fr
Anticipated expiration legal-status Critical
Publication of WO2001031579A3 publication Critical patent/WO2001031579A3/fr
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/70—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F18/00—Pattern recognition
    • G06F18/20—Analysing
    • G06F18/21—Design or setup of recognition systems or techniques; Extraction of features in feature space; Blind source separation
    • G06F18/211—Selection of the most significant subset of features
    • G06F18/2115—Selection of the most significant subset of features by evaluating different subsets according to an optimisation criterion, e.g. class separability, forward selection or backward elimination
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F18/00—Pattern recognition
    • G06F18/20—Analysing
    • G06F18/21—Design or setup of recognition systems or techniques; Extraction of features in feature space; Blind source separation
    • G06F18/214—Generating training patterns; Bootstrap methods, e.g. bagging or boosting
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20—Supervised data analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/30—Unsupervised data analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/40—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Data Mining & Analysis (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Theoretical Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Epidemiology (AREA)
  • Evolutionary Computation (AREA)
  • Artificial Intelligence (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Databases & Information Systems (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Bioethics (AREA)
  • Software Systems (AREA)
  • Primary Health Care (AREA)
  • Genetics & Genomics (AREA)
  • General Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention se rapporte à des procédés, à des systèmes et à des dispositifs qui font appel à des machines vectorielles de soutien permettant l'identification de motifs qui s'avèrent importants s'agissant de diagnostic, pronostic et traitement médical. Ces motifs peuvent être trouvés dans de nombreux ensembles de données différents. La présente invention se rapporte également à des procédés et à des compositions permettant le traitement et le diagnostic d'états pathologiques.
PCT/US2000/029712 1999-10-27 2000-10-27 Procedes et dispositifs permettant d'identifier des motifs dans des systemes biologiques et procedes d'utilisation correspondants Ceased WO2001031579A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU13505/01A AU1350501A (en) 1999-10-27 2000-10-27 Methods and devices for identifying patterns in biological systems and methods for uses thereof

Applications Claiming Priority (16)

Application Number Priority Date Filing Date Title
US16180699P 1999-10-27 1999-10-27
US16870399P 1999-12-02 1999-12-02
US18459600P 2000-02-24 2000-02-24
US19121900P 2000-03-22 2000-03-22
US09/568,301 US6427141B1 (en) 1998-05-01 2000-05-09 Enhancing knowledge discovery using multiple support vector machines
US09/578,011 US6658395B1 (en) 1998-05-01 2000-05-24 Enhancing knowledge discovery from multiple data sets using multiple support vector machines
US20702600P 2000-05-25 2000-05-25
US09/568,301 2000-05-25
US60/191,219 2000-05-25
US60/168,703 2000-05-25
US60/207,026 2000-05-25
US60/184,596 2000-05-25
US60/161,806 2000-05-25
US09/578,011 2000-05-25
US09/633,850 2000-08-07
US09/633,850 US6789069B1 (en) 1998-05-01 2000-08-07 Method for enhancing knowledge discovered from biological data using a learning machine

Publications (2)

Publication Number Publication Date
WO2001031579A2 WO2001031579A2 (fr) 2001-05-03
WO2001031579A3 true WO2001031579A3 (fr) 2002-07-11

Family

ID=27575021

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/029712 Ceased WO2001031579A2 (fr) 1999-10-27 2000-10-27 Procedes et dispositifs permettant d'identifier des motifs dans des systemes biologiques et procedes d'utilisation correspondants

Country Status (2)

Country Link
AU (1) AU1350501A (fr)
WO (1) WO2001031579A2 (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7096206B2 (en) 2000-06-19 2006-08-22 Correlogic Systems, Inc. Heuristic method of classification
BR0112667A (pt) 2000-07-18 2006-05-09 Correlogic Systems Inc processo de distinção entre estados biológicos baseados em padrões ocultos de dados biológicos
CA2429327A1 (fr) 2000-11-16 2003-04-17 Ciphergen Biosystems, Inc. Procede d'analyse de spectres de masse
WO2003015001A2 (fr) * 2001-08-03 2003-02-20 Synt:Em S.A. Méthode d'identification de la fonction protéique
EP1449108A4 (fr) * 2001-11-07 2006-11-22 Health Discovery Corp Classement de caracteristiques pretraitees pour une machine a vecteur de support
JP3896868B2 (ja) 2002-02-27 2007-03-22 日本電気株式会社 パターンの特徴選択方法及び分類方法及び判定方法及びプログラム並びに装置
AR040711A1 (es) 2002-07-29 2005-04-13 Us Agriculture Un metodo para verificacion de calidad/control de calidad para proceso de bioensayo de alto rendimiento
WO2004061410A2 (fr) 2002-12-18 2004-07-22 Ciphergen Biosystems, Inc. Biomarqueurs seriques du cancer du poumon
US7072772B2 (en) 2003-06-12 2006-07-04 Predicant Bioscience, Inc. Method and apparatus for modeling mass spectrometer lineshapes
JP4774534B2 (ja) 2003-12-11 2011-09-14 アングーク ファーマシューティカル カンパニー，リミティド 集中化適応モデル及び遠隔操作サンプルプロセッシングの使用を介した生物学的状態の診断方法
CN101855553B (zh) 2007-06-29 2014-06-11 韩国安国药品株式会社 卵巢癌的预测标记
AU2009212193B2 (en) * 2008-02-08 2015-08-27 Health Discovery Corporation Method and system for analysis of flow cytometry data using support vector machines
CA2750155A1 (fr) 2008-12-30 2010-07-08 Centocor Ortho Biotech Inc. Marqueurs seriques predisant la reponse clinique a des anticorps anti-tnf.alpha. chez les patients souffrant de spondylarthrite ankylosante
US8972899B2 (en) 2009-02-10 2015-03-03 Ayasdi, Inc. Systems and methods for visualization of data analysis
US8738303B2 (en) 2011-05-02 2014-05-27 Azure Vault Ltd. Identifying outliers among chemical assays
US8660968B2 (en) 2011-05-25 2014-02-25 Azure Vault Ltd. Remote chemical assay classification
US10288626B2 (en) 2012-09-14 2019-05-14 University Of Kentucky Research Foundation Secreted tumor-associated cytochrome as a blood-based biomarker for cancer
US10776760B2 (en) 2017-11-17 2020-09-15 The Boeing Company Machine learning based repair forecasting
CN109460420A (zh) * 2018-09-28 2019-03-12 北京赛博贝斯数据科技有限责任公司 结构化数据的知识挖掘方法及系统
CN111612231B (zh) * 2020-05-13 2023-09-01 云南电网有限责任公司电力科学研究院 一种配网线路重跳模型融合处理方法及装置
US12227307B2 (en) 2020-07-22 2025-02-18 The Boeing Company Predictive maintenance model design system

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999022019A1 (fr) * 1997-10-29 1999-05-06 Rutgers, The State University Of New Jersey Etablissement d'un lien entre une sequence genique et une fonction genique par determination de la structure proteique tridimensionnelle
WO1999053101A1 (fr) * 1998-04-13 1999-10-21 Isis Pharmaceuticals, Inc. Identification de cibles genetiques destinees a etre modulees par des oligonucleotides et formation d'oligonucleotides destines a subir une modulation genique
WO1999057622A2 (fr) * 1998-05-01 1999-11-11 Barnhill Technologies, Llc Pre-traitement et post-traitement permettant d'ameliorer la decouverte de connaissances au moyen de machines a vecteurs de soutien

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999022019A1 (fr) * 1997-10-29 1999-05-06 Rutgers, The State University Of New Jersey Etablissement d'un lien entre une sequence genique et une fonction genique par determination de la structure proteique tridimensionnelle
WO1999053101A1 (fr) * 1998-04-13 1999-10-21 Isis Pharmaceuticals, Inc. Identification de cibles genetiques destinees a etre modulees par des oligonucleotides et formation d'oligonucleotides destines a subir une modulation genique
WO1999057622A2 (fr) * 1998-05-01 1999-11-11 Barnhill Technologies, Llc Pre-traitement et post-traitement permettant d'ameliorer la decouverte de connaissances au moyen de machines a vecteurs de soutien

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
AMARI S ET AL: "Improving support vector machine classifiers by modifying kernel functions", NEURAL NETWORKS, ELSEVIER SCIENCE PUBLISHERS, BARKING, GB, vol. 12, no. 6, July 1999 (1999-07-01), pages 783 - 789, XP004174075, ISSN: 0893-6080 *
MORIK K ET AL: "COMBINING STATISTICAL LEARNING WITH A KNOWLEDGE-BASED APPROACH -A CASE STUDY IN INTENSIVE CARE MONITORING", MACHINE LEARNING. PROCEEDINGS OF THE INTERNATIONAL CONFERENCE, XX, XX, 27 June 1999 (1999-06-27), pages 268 - 277, XP001030158 *
SUGAYA S ET AL: "Support vector machines for knowledge discovery", PRINCIPLES OF DATA MINING AND KNOWLEDGE DISCOVERY. THIRD EUROPEAN CONFERENCE, PKDD'99. PROCEEDINGS. (LECTURE NOTES IN ARTIFICIAL INTELLIGENCE VOL.1704), PRINCIPLES OF DATA MINING AND KNOWLEDGE DISCOVERY. THIRD EUROPEAN CONFERENCE, PKDD'99, PRAGUE, CZ, 1999, Berlin, Germany, Springer-Verlag, Germany, pages 561 - 567, XP001030152, ISBN: 3-540-66490-4 *

Also Published As

Publication number Publication date
WO2001031579A2 (fr) 2001-05-03
AU1350501A (en) 2001-05-08

Similar Documents

Publication Publication Date Title
WO2001031580A3 (fr) Procedes et dispositifs pouvant identifier des modeles dans des systemes biologiques, et procedes d'utilisation
WO2001031579A3 (fr) Procedes et dispositifs permettant d'identifier des motifs dans des systemes biologiques et procedes d'utilisation correspondants
WO2002059822A3 (fr) Procedes d'identification de motifs dans des systemes biologiques et utilisations desdits procedes
WO1999054286A3 (fr) Inhibiteurs btk et leurs procedes d'identification et d'utilisation
AU2002361602A1 (en) Identity card and system for tracking the use of the card
WO2001036977A3 (fr) Procedes et compositions d'identification de marqueurs de maladie
MXPA03005389A (es) Metodos y aparatos para procesar selectivamente huevos que tienen caracteristicas identificadas.
AU2002257615A1 (en) Methods and devices for treating and/or processing data
WO1999036550A3 (fr) Molecules de proteases humaines
AU2002366641A1 (en) Methods for inhibiting ocular processes
AU2002325835A1 (en) Treatment method, which promotes the removal of dirt, for the surfaces of textiles and non-textiles
WO2002103103A3 (fr) Composes contenant du fluor et polymeres derives de ces composes
WO2001075178A3 (fr) Methodes d'identification d'aptameres peptidiques pouvant alterer un phenotype cellulaire
EP1800691A3 (fr) Compositions et procédés permettant la prévention ou le traitement du cancer et de la perte osseuse associée au cancer
TWI268199B (en) Polishing system comprising a highly branched polymer
WO2002098355A3 (fr) Methodes et compositions pour diagnostic et traitement de la resistance a l'insuline et des etats associes
ATE318328T1 (de) Diagnostika und therapeutika für osteoporose
WO2004087066A3 (fr) Inhibiteurs de hif-1
EP1376359A3 (fr) Traitement des informations de configuration pour dispositifs de stockage réseau
WO1999041373A3 (fr) Molecules humaines associees au transport
WO2003044047A3 (fr) Genes de virulence, proteines, et leurs utilisations
WO2003028536A3 (fr) Methodes permettant de diagnostiquer et de traiter les maladies cardiaques
NZ514691A (en) Method to type prion proteins
WO2002072883A3 (fr) Support nucleotidique destine au diagnostic et a la therapie de maladies buccales
WO2003091690A3 (fr) Acides nucleiques et polypeptides associes au cancer

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

AK Designated states

Kind code of ref document: A3

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP