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WO2001028975A3 - Procede de production de 3-nitryloxy-2,2-bis(nitryloxymethyl)-propanal - Google Patents

Procede de production de 3-nitryloxy-2,2-bis(nitryloxymethyl)-propanal Download PDF

Info

Publication number
WO2001028975A3
WO2001028975A3 PCT/DE2000/003677 DE0003677W WO0128975A3 WO 2001028975 A3 WO2001028975 A3 WO 2001028975A3 DE 0003677 W DE0003677 W DE 0003677W WO 0128975 A3 WO0128975 A3 WO 0128975A3
Authority
WO
WIPO (PCT)
Prior art keywords
nitryloxymethyl
nitryloxy
propanal
bis
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/DE2000/003677
Other languages
German (de)
English (en)
Other versions
WO2001028975A2 (fr
Inventor
Ulrich Hess
Holger Brosig
Gerd Koenig
Michael Stoeter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Puren Pharma GmbH and Co KG
Original Assignee
Alpharma Isis GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alpharma Isis GmbH and Co KG filed Critical Alpharma Isis GmbH and Co KG
Priority to AU21483/01A priority Critical patent/AU2148301A/en
Priority to DE10083167T priority patent/DE10083167D2/de
Publication of WO2001028975A2 publication Critical patent/WO2001028975A2/fr
Publication of WO2001028975A3 publication Critical patent/WO2001028975A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/02—Preparation of esters of nitric acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Emergency Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'invention concerne un procédé de production de 3-nitryloxy-2,2-bis(nitryloxyméthyl)-propanal.
PCT/DE2000/003677 1999-10-19 2000-10-19 Procede de production de 3-nitryloxy-2,2-bis(nitryloxymethyl)-propanal Ceased WO2001028975A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU21483/01A AU2148301A (en) 1999-10-19 2000-10-19 Method for production of 3-nitryloxy-2,2-bis(nitryloxymethyl)-propanal
DE10083167T DE10083167D2 (de) 1999-10-19 2000-10-19 Verfahren zur Herstellung von 3-Nitryloxy-2,2-bis(Nitryloxymethyl)-Propanal

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19950483.0 1999-10-19
DE1999150483 DE19950483A1 (de) 1999-10-19 1999-10-19 Verfahren zur Herstellung von 3-Nitryloxy-2,2-bis(nitryloxymethyl)-propanal

Publications (2)

Publication Number Publication Date
WO2001028975A2 WO2001028975A2 (fr) 2001-04-26
WO2001028975A3 true WO2001028975A3 (fr) 2002-02-28

Family

ID=7926254

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE2000/003677 Ceased WO2001028975A2 (fr) 1999-10-19 2000-10-19 Procede de production de 3-nitryloxy-2,2-bis(nitryloxymethyl)-propanal

Country Status (3)

Country Link
AU (1) AU2148301A (fr)
DE (2) DE19950483A1 (fr)
WO (1) WO2001028975A2 (fr)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE932793C (de) * 1953-11-28 1955-09-08 Riedel De Haeen Ag Verfahren zur Herstellung von aromatischen Nitrocarbonylverbindungen
WO1998015521A1 (fr) * 1996-10-10 1998-04-16 Isis Pharma Gmbh Nouveaux derives de la pentaerythrite, leur production, leur utilisation, et intermediaires pour leur synthese
WO1998056759A2 (fr) * 1997-06-11 1998-12-17 Isis Pharma Gmbh Nouveaux derives de pentaerythrite, leur production, leur utilisation et intermediaires pour leur synthese
WO1999067430A2 (fr) * 1998-06-24 1999-12-29 Alpharma-Isis Gmbh & Co. Kg Substrats analytiques et agents antioxydants

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE932793C (de) * 1953-11-28 1955-09-08 Riedel De Haeen Ag Verfahren zur Herstellung von aromatischen Nitrocarbonylverbindungen
WO1998015521A1 (fr) * 1996-10-10 1998-04-16 Isis Pharma Gmbh Nouveaux derives de la pentaerythrite, leur production, leur utilisation, et intermediaires pour leur synthese
WO1998056759A2 (fr) * 1997-06-11 1998-12-17 Isis Pharma Gmbh Nouveaux derives de pentaerythrite, leur production, leur utilisation et intermediaires pour leur synthese
WO1999067430A2 (fr) * 1998-06-24 1999-12-29 Alpharma-Isis Gmbh & Co. Kg Substrats analytiques et agents antioxydants

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
BULL. ACAD. POL. SCI., SER. SCI. CHIM., vol. 18, no. 7, 1970, pages 385 - 390 *
CHEMICAL ABSTRACTS, vol. 100, no. 16, 16 April 1984, Columbus, Ohio, US; abstract no. 129741e, MILES, M. HOWARD ET AL.: "Free radicals in gamma-irradiated PETN" page 553; column 2; XP002161973 *
CHEMICAL ABSTRACTS, vol. 100, no. 24, 11 June 1984, Columbus, Ohio, US; abstract no. 194541d, MILES, MAURICE ET AL.: "Molecular decomposition of polymeric binders and energetic materials." page 153; column 1; XP002161975 *
CHEMICAL ABSTRACTS, vol. 109, no. 8, 22 August 1988, Columbus, Ohio, US; abstract no. 64640k, VARENTSOV, E. A. ET AL.: "Formation of radicals during the fracture of organic molecular crystals." page 678; column 1; XP002161974 *
CHEMICAL ABSTRACTS, vol. 129, no. 11, 14 September 1998, Columbus, Ohio, US; abstract no. 131056c, DIKALOV, S. ET AL.: "Most nitrovasodilators except PETN induce formation of reactive oxygen species and nitrate tolerance in vascular cells." page 34; column 2; XP002161976 *
CHEMICAL ABSTRACTS, vol. 74, no. 13, 29 March 1971, Columbus, Ohio, US; abstract no. 63726q, HETNARSKI ET AL.: "Esters of nitric acid as electron acceptors." page 265; column 1; XP002161972 *
IND. ENG. CHEM. PROD. RES. DEV., vol. 23, no. 2, 1984, pages 304 - 307 *
J. MATER. SCI., vol. 19, no. 2, 1984, pages 467 - 472 *
PORTLAND PRESS PROC., vol. 15, no. 6, 1998, pages 299 *
ZH. FIZ. KHIM., vol. 62, no. 4, 1988, pages 1089 - 1091 *

Also Published As

Publication number Publication date
DE10083167D2 (de) 2002-09-05
AU2148301A (en) 2001-04-30
WO2001028975A2 (fr) 2001-04-26
DE19950483A1 (de) 2001-05-10

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